punch biopsy (... BY-op-see)
A procedure in which a small round piece of tissue about the size of a pencil eraser is removed using a sharp, hollow, circular instrument. The tissue is then checked under a microscope for signs of disease. A punch biopsy may be used to check for certain types of cancer, including skin, vulvar, and cervical cancer. It may also be used to check for certain skin conditions and changes that may lead to cancer.