Definition:

stage III melanomalisten (... MEH-luh-NOH-muh)

The tumor may be any thickness, with or without ulceration (a break in the skin), and one or more of the following is true: (1) cancer has spread to one or more lymph nodes; (2) lymph nodes may be joined together (matted); (3) cancer may be in a lymph vessel between the primary tumor and nearby lymph nodes; and/or (4) very small tumors may be found on or under the skin, not more than 2 centimeters away from where the cancer first started.

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Stage III melanoma; drawing shows a primary tumor on the lower arm. In the top inset, cancer is shown (a) in lymph nodes near a blood vessel. In the bottom inset, cancer is shown (b) in lymph nodes that are joined together (matted), (c) in a lymph vessel, and (d) not more than 2 centimeters away from the primary tumor.

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