stage IV maxillary sinus cancer (...MAK-sih-LAYR-ee SY-nus KAN-ser)
Stage IV maxillary sinus cancer is divided into stages IVA, IVB, and IVC. In stage IVA, cancer (1) has spread to one lymph node on the same side of the neck as the cancer and the lymph node is larger than 3 centimeters but not larger than 6 centimeters; or to more than one lymph node on the same side of the neck as the original tumor and the lymph nodes are not larger than 6 centimeters; or to lymph nodes on the opposite side of the neck as the original tumor or on both sides of the neck, and the lymph nodes are not larger than 6 centimeters, and cancer has also spread to any of the following: the lining of the maxillary sinus, bones around the maxillary sinus (including the roof of the mouth and the nose), tissues under the skin, the eye socket, the base of the skull, and/or the ethmoid sinuses; or (2) has spread to any of the following: the front of the eye, skin of the cheek, base of the skull, behind the jaw, the bone between the eyes, and/or the sphenoid or frontal sinuses, and cancer may also have spread to one or more lymph nodes 6 centimeters or smaller, anywhere in the neck. In stage IVB, cancer (1) has spread to any of the following: the back of the eye, brain, middle parts of the skull, nerves in the head that go to the brain, upper part of the throat behind the nose, and/or the base of the skull, and cancer may be found in one or more lymph nodes of any size, anywhere in the neck; or (2) is found in a lymph node larger than 6 centimeters. Cancer may also be found anywhere in or near the maxillary sinus. In stage IVC, cancer may be anywhere in or near the maxillary sinus, may have spread to lymph nodes, and has spread to organs far away from the maxillary sinus, such as the lungs.