Clinical Trials Search Results

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Initial search results include only NCI-sponsored clinical trials. To search all trials, click the "REFINE SEARCH" button, scroll down to the Trial ID/Sponsor section and select the "All" check box in the Sponsor of Trial section.

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Drug:  metformin hydrochloride
Find trials that include:  Any drugs shown
Trial Status:  Active
Results 1-25 of 81 for your search:
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Paclitaxel and Carboplatin With or Without Metformin Hydrochloride in Treating Patients With Stage III, IV, or Recurrent Endometrial Cancer
Phase: Phase III, Phase II
Type: Biomarker/Laboratory analysis, Treatment
Status: Active
Age: 18 and over
Sponsor: NCI, Other
Protocol IDs: GOG-0286B, NCI-2013-02284, U10CA027469, U10CA180868, NCT02065687
An Endometrial Cancer Chemoprevention Study of Metformin
Phase: Phase III
Type: Behavioral study, Biomarker/Laboratory analysis, Prevention
Status: Active
Age: 50 to 60
Sponsor: NCI, Other
Protocol IDs: 2011-0739, 5P50-CA098258, NCI-2013-00834, NCT01697566
The Metformin Active Surveillance Trial (MAST) Study
Phase: Phase III
Type: Biomarker/Laboratory analysis, Treatment
Status: Active
Age: 18 to 79
Sponsor: Other
Protocol IDs: MAST 01, NCT01864096
Metformin Hydrochloride in Patients With Atypical Hyperplasia or In Situ Breast Cancer to Placebo in Decreasing Atypical Cells in Patients With Atypical Hyperplasia or in Situ Breast Cancer
Phase: Phase III
Type: Biomarker/Laboratory analysis, Prevention, Treatment
Status: Approved-not yet active
Age: 25 to 55
Sponsor: NCI, Other
Protocol IDs: A211102, U10CA031946, NCI-2013-00995, NCT01905046
Placebo Controlled Double Blind Crossover Trial of Metformin for Brain Repair in Children With Cranial-Spinal Radiation for Medulloblastoma
Phase: Phase III
Type: Supportive care
Status: Active
Age: 5 to 17
Sponsor: Other
Protocol IDs: 1000039383, NCT02040376
Primary Prevention Hepatocellular Carcinoma by Metformin
Phase: Phase III
Type: Prevention
Status: Approved-not yet active
Age: 18 and over
Sponsor: Other
Protocol IDs: P120138, NCT02319200
Gemcitabine+Nab-paclitaxel and FOLFIRINOX and Molecular Profiling for Patients With Advanced Pancreatic Cancer
Phase: Phase II, Phase I
Type: Biomarker/Laboratory analysis, Treatment
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: PCRT 11-002, NCT01488552
A Phase I/II Trial of Vemurafenib and Metformin to Melanoma Patients
Phase: Phase II, Phase I
Type: Treatment
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: BCC-MEL-11-03, NCT01638676
A Study of Metformin With or Without Rapamycin as Maintenance Therapy After Induction Chemotherapy in Subjects With Pancreatic Cancer
Phase: Phase II, Phase I
Type: Treatment
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: J13146, NA_00090282, NCT02048384
Study of Dabrafenib, Trametinib and Metformin for Melanoma Patients
Phase: Phase II, Phase I
Type: Treatment
Status: Active
Age: Over 18
Sponsor: Other
Protocol IDs: BCC-MEL-14-01, NCT02143050
Efficacy and Safety of Adjuvant Metformin for Operable Breast Cancer Patients
Phase: Phase II
Type: Treatment
Status: Active
Age: 20 and over
Sponsor: Other
Protocol IDs: adjuvant metformin for BC, NCT00909506
A Trial of Standard Chemotherapy With Metformin (vs Placebo) in Women With Metastatic Breast Cancer
Phase: Phase II
Type: Biomarker/Laboratory analysis, Treatment
Status: Active
Age: 18 to 75
Sponsor: Other
Protocol IDs: OZM-027, NCT01310231
Exercise and Metformin in Colorectal and Breast Cancer Survivors
Phase: Phase II
Type: Biomarker/Laboratory analysis, Educational/Counseling/Training, Treatment
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: 11-009, NCT01340300
Phase II Short-term Adjuvant Therapy and Biomarker Studies With Targeted Agents in Women With Estrogen Receptor Negative Breast Cancer
Phase: Phase II
Type: Biomarker/Laboratory analysis, Prevention
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: 2010-0794, NCI-2012-00037, KG09 1020, NCT01471106
Study of Metformin With Simvastatin for Men With Prostate Carcinoma
Phase: Phase II
Type: Treatment
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: H-28936, NCT01561482
Metformin Plus Neoadjuvant Chemotherapy in Breast Cancer
Phase: Phase II
Type: Treatment
Status: Approved-not yet active
Age: 18 to 70
Sponsor: Other
Protocol IDs: MET-INCAN-1, NCT01566799
Evaluation of Metformin, Targeting Cancer Stem Cells for Prevention of Relapse in Gynecologic Patients
Phase: Phase II
Type: Treatment
Status: Active
Age: 19 to 79
Sponsor: Other
Protocol IDs: UMCC 2011.037, HUM 47900, NCT01579812
Neoadjuvant Letrozole Plus Metformin vs Letrozole Plus Placebo for ER-positive Postmenopausal Breast Cancer
Phase: Phase II
Type: Treatment
Status: Active
Age: 18 to 80
Sponsor: Other
Protocol IDs: KBCSG 013, NCT01589367
Castration Compared to Castration Plus Metformin as First Line Treatment for Patients With Advanced Prostate Cancer
Phase: Phase II
Type: Treatment
Status: Active
Age: 18 and over
Sponsor: Other
Protocol IDs: CTRC 10-21, HSC20110273H, NCT01620593
Metformin Plus Modified FOLFOX 6 in Metastatic Pancreatic Cancer
Phase: Phase II
Type: Biomarker/Laboratory analysis, Treatment
Status: Active
Age: 18 and over
Sponsor: NCI, Other
Protocol IDs: CASE1212, NCI-2012-01322, NCT01666730
Impact of the Addition of Metformin to Abiraterone in Metastatic Prostate Cancer Patients
Phase: Phase II
Type: Treatment
Status: Active
Age: 18 to 90
Sponsor: Other
Protocol IDs: MetAb-Pro, NCT01677897
Improving the Treatment for Women With Early Stage Cancer of the Uterus
Phase: Phase II
Type: Treatment
Status: Active
Age: Over 18
Sponsor: Other
Protocol IDs: feMMe, NCT01686126
Metformin as a Chemoprevention Agent in Non-small Cell Lung Cancer
Phase: Phase II
Type: Prevention
Status: Active
Age: Over 18
Sponsor: Other
Protocol IDs: 12-006865, NCT01717482
The Chemopreventive Effect of Metformin in Patients With Familial Adenomatous Polyposis: Double Blinded Randomized Controlled Study
Phase: Phase II
Type: Prevention
Status: Active
Age: 20 to 65
Sponsor: Other
Protocol IDs: 4-2012-0491, NCT01725490
A Pilot Study of Metformin Therapy in Patients With Relapsed Chronic Lymphocytic Leukemia (CLL) and Untreated CLL
Phase: Phase II
Type: Treatment
Status: Active
Age: 18 to 80
Sponsor: Other
Protocol IDs: UMCC 2012.025, NCT01750567
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