Radiation Therapy With or Without Chemotherapy in Patients With Stage I or Stage II Cervical Cancer Who Previously Underwent Surgery

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Basic Trial Information

PhaseTypeAgeTrial IDs
Phase IIITissue collection/Repository, Treatment18 and overGOG-0263
NCI-2011-02037, CDR0000670125, NCT01101451

Trial Description

Summary

This randomized phase III trial studies radiation therapy with chemotherapy to see how well it works compared to radiation therapy alone in treating patients with stage I or stage II cervical cancer who previously underwent surgery. Radiation therapy uses high-energy x-rays to kill tumor cells. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. It is not yet known whether giving radiation therapy together with chemotherapy is more effective than radiation therapy alone in treating patients with cervical cancer.

Further Study Information

PRIMARY OBJECTIVES:

I. To determine if post-operative adjuvant chemo-radiation therapy (CRT) can significantly improve recurrence-free survival (RFS) when compared to radiation therapy (RT) alone in stage I-IIA cervical cancer patients with intermediate-risk factors after treatment with radical hysterectomy.

SECONDARY OBJECTIVES:

I. To determine whether post-operative adjuvant CRT can improve overall survival (OS) when compared to RT alone in stage I-IIA cervical cancer patients with intermediate risk factors after treatment with radical hysterectomy.

II. To assess differences (across treatment arms) in incidence and severity of therapy-attributed adverse events utilizing the active version of Common Terminology Criteria for Adverse Events (CTCAE).

III. To provide assessment of patient risk vs benefit (positive study only).

IV. To determine whether post-operative adjuvant CRT improves the health-related quality-of-life (QOL) (compared to RT alone) as measured by Functional Assessment of Cancer Therapy-Cervix (FACT-Cx) Trial Outcome Index (TOI) and produce favorable toxicity profiles (with particular focus on treatment related genitourinary, gastrointestinal, neurological, pain and sexual adverse events).

TERTIARY OBJECTIVES:

I. To bank archival tumor tissue for research studies, including studies that evaluate the association between biomarkers, RFS, OS, and clinical-surgical-pathologic characteristics in patients randomized to post-operative adjuvant CRT compared to RT alone.

II. To bank deoxyribonucleic acid (DNA) from whole blood for research studies, including studies that evaluate associations between single nucleotide polymorphisms (SNPs), and measures of clinical outcome, including RFS, OS, and adverse events in patients randomized to post-operative adjuvant CRT compared to RT alone.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients undergo pelvic external-beam radiation therapy (EBRT) or intensity-modulated radiation therapy (IMRT) 5 days a week for 5.5 weeks.

ARM II: Patients receive cisplatin IV over 1-2 hours on day 1 and undergo radiotherapy as in Arm I. Treatment with cisplatin repeats every 7 days for up to 6 courses in the absence of disease progression or unacceptable toxicity.

After completion of study therapy, patients are followed up every 3 months for 2 years, every 6 months for 3 years, and then annually thereafter.

Eligibility Criteria

Inclusion Criteria:

Serum glutamic oxaloacetic transaminase (SGOT) ≤ 3 times normal

Absolute neutrophil count (ANC) ≥ 1,500/mcl

Platelets ≥ 100,000/mcl

Bilirubin ≤ 1.5 times normal

Creatinine ≤ upper limit of normal (ULN) or calculated creatinine clearance ≥ 60 mL/min

Alkaline phosphate ≤ 3 times normal

Patients must have signed an approved informed consent and authorization permitting release of personal health information

Pathologically proven primary cervical cancer I-IIA with squamous cell carcinoma, adenosquamous carcinoma or adenocarcinoma initially treated with a standard radical hysterectomy with pelvic lymphadenectomy

Patients with the following characteristics (depth of stromal invasion and lymphovascular space involvement to be pathologically confirmed):

Positive capillary-lymphovascular space involvement and one of the following:

  • Deep third penetration
  • Middle third penetration, clinical tumor ≥ 2 cm
  • Superficial third penetration, clinical tumor ≥ 5 cm

Negative capillary-lymphatic space involvement

  • Middle or deep third penetration, clinical tumor ≥ 4 cm

Gynecologic Oncology Group (GOG) performance status 0, 1, 2

Patients should not be randomized less than 3 weeks post-surgery but will not be acceptable for randomization more than 8 weeks post-surgery

Patients who have met the pre-entry requirements

Exclusion Criteria:

Patients with tumor in the parametria, pelvic lymph nodes or any other extra uterine site or with positive surgical margins

Patients with septicemia or severe infection

Patients with intestinal obstruction or gastrointestinal bleeding

Patients with postoperative fistula

Patients with cervix cancer who have received any previous radiation or chemotherapy

Patients whose circumstances do not permit completion of the study or the required follow-up

Patients with a history of other invasive malignancies, with the exception of non-melanoma skin cancer, are excluded if there is any evidence of other malignancy being present within the last five years; patients are also excluded if their previous cancer treatment contraindicates this protocol therapy

Patients with GOG performance status of 3 or 4

Patients with renal abnormalities requiring modification of radiation field (pelvic kidney, renal transplant, etc.)

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

Gynecologic Oncology Group

  • National Cancer Institute
Sang Young Ryu, Principal Investigator

Trial Sites

U.S.A.

Alaska
Anchorage

Alaska Breast Care and Surgery LLC

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Alaska Women's Cancer Care

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Anchorage Oncology Centre

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Katmai Oncology Group

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Providence Alaska Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Fairbanks

Fairbanks Memorial Hospital

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Arizona
Phoenix

Saint Joseph's Hospital and Medical Center

John Hall Farley
Ph: 301-319-2100

John Hall Farley
Principal Investigator

California
Auburn

Sutter Auburn Faith Hospital

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sutter Cancer Centers Radiation Oncology Services-Auburn

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Berkeley

Alta Bates Summit Medical Center-Herrick Campus

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Burbank

Providence Saint Joseph Medical Center/Disney Family Cancer Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Burlingame

Mills - Peninsula Hospitals

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Cameron Park

Sutter Cancer Centers Radiation Oncology Services-Cameron Park

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Concord

John Muir Medical Center-Concord Campus

Babak Edraki
Ph: 925-674-2580

Babak Edraki
Principal Investigator

Davis

Sutter Davis Hospital

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Loma Linda

Loma Linda University Medical Center

Yevgeniya Jane Mikhailovn Ioffe
Ph: 909-558-4050

Yevgeniya Jane Mikhailovn Ioffe
Principal Investigator

Modesto

Memorial Medical Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Mountain View

Palo Alto Medical Foundation-Camino Division

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Palo Alto Medical Foundation-Gynecologic Oncology

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Novato

Sutter Cancer Research Consortium

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Orange

UC Irvine Health/Chao Family Comprehensive Cancer Center

Krishnansu Sujata Tewari
Ph: 714-456-6191
Email: awallick@uci.edu

Krishnansu Sujata Tewari
Principal Investigator

Palo Alto

Palo Alto Medical Foundation Health Care

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Pomona

Pomona Valley Hospital Medical Center

Yallapragada S. (Ram) Rao
Ph: 909-865-9555

Yallapragada S. (Ram) Rao
Principal Investigator

Roseville

Sutter Cancer Centers Radiation Oncology Services-Roseville

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sutter Roseville Medical Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sacramento

Sutter General Hospital

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

San Francisco

California Pacific Medical Center-Pacific Campus

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Santa Rosa

Sutter Pacific Medical Foundation

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sunnyvale

Palo Atlo Medical Foundation-Sunnyvale

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Sylmar

Olive View-University of California Los Angeles Medical Center

Christine H. Holschneider
Ph: 888-798-0719

Christine H. Holschneider
Principal Investigator

Vacaville

Sutter Cancer Centers Radiation Oncology Services-Vacaville

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Vallejo

Sutter Solano Medical Center/Cancer Center

John K. Chan
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

John K. Chan
Principal Investigator

Walnut Creek

John Muir Medical Center-Walnut Creek

Babak Edraki
Ph: 925-674-2580

Babak Edraki
Principal Investigator

Colorado
Aurora

Rocky Mountain Cancer Centers-Aurora

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

The Medical Center of Aurora

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Boulder

Boulder Community Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Colorado Springs

Penrose-Saint Francis Healthcare

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Penrose

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Denver

Colorado Blood Cancer Institute

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Colorado Cancer Research Program CCOP

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Exempla Saint Joseph Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Porter Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Presbyterian - Saint Lukes Medical Center - Health One

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Midtown

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Rose

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rose Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Durango

Mercy Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Southwest Oncology PC

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Englewood

Comprehensive Cancer Care and Research Institute of Colorado LLC

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Swedish Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Golden

Mountain Blue Cancer Care Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Greeley

North Colorado Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Greenwood Village

Rocky Mountain Cancer Centers-Greenwood Village

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Saint Anthony Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Littleton

Littleton Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Littleton

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Lone Tree

Rocky Mountain Cancer Centers-Sky Ridge

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Sky Ridge Medical Center

Eduardo R. Pajon
Ph: 888-336-8262

Eduardo R. Pajon
Principal Investigator

Longmont

Longmont United Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Longmont

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Loveland

McKee Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Parker

Parker Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Rocky Mountain Cancer Centers-Parker

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Pueblo

Rocky Mountain Cancer Centers - Pueblo

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Saint Mary Corwin Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Thornton

Rocky Mountain Cancer Centers-Thornton

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Wheat Ridge

Exempla Lutheran Medical Center

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Connecticut
Hartford

Hartford Hospital

James S. Hoffman
Ph: 860-224-5660

James S. Hoffman
Principal Investigator

Saint Francis Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

New Britain

The Hospital of Central Connecticut

James S. Hoffman
Ph: 860-224-5660

James S. Hoffman
Principal Investigator

New Haven

Yale University

Masoud Azodi
Ph: 203-785-5702

Masoud Azodi
Principal Investigator

District of Columbia
Washington

Sibley Memorial Hospital

Mildred R. Chernofsky
Ph: 202-243-2373

Mildred R. Chernofsky
Principal Investigator

Florida
Deerfield Beach

University of Miami Sylvester Comprehensive Cancer Center at Deerfield Beach

Aaron H. Wolfson
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Aaron H. Wolfson
Principal Investigator

Miami

Jackson Memorial Hospital-Holtz Children's Hospital

Aaron H. Wolfson
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Aaron H. Wolfson
Principal Investigator

University of Miami Miller School of Medicine-Sylvester Cancer Center

Aaron H. Wolfson
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Aaron H. Wolfson
Principal Investigator

Georgia
Atlanta

Northside Hospital

Guilherme Henrique C. Cantuaria
Ph: 404-303-3355
Email: clinicaltrials@northside.com

Guilherme Henrique C. Cantuaria
Principal Investigator

Piedmont Hospital

Adam Wayne Nowlan
Ph: 404-425-7943
Email: ORS@piedmont.org

Adam Wayne Nowlan
Principal Investigator

Saint Joseph's Hospital of Atlanta

Thomas Edwin Seay
Ph: 404-303-3355

Thomas Edwin Seay
Principal Investigator

Columbus

John B Amos Cancer Center

Gregory Peter Sfakianos
Ph: 706-660-6404

Gregory Peter Sfakianos
Principal Investigator

Decatur

Dekalb Medical Center

Thomas Edwin Seay
Ph: 404-303-3355

Thomas Edwin Seay
Principal Investigator

Gainesville

Northeast Georgia Medical Center

Andrew Emmons Green
Ph: 770-219-8800
Email: cancerpatient.navigator@nghs.com

Andrew Emmons Green
Principal Investigator

Marietta

Wellstar Kennestone Hospital

Thomas Edwin Seay
Ph: 404-303-3355

Thomas Edwin Seay
Principal Investigator

Riverdale

Southern Regional Medical Center

Thomas Edwin Seay
Ph: 404-303-3355

Thomas Edwin Seay
Principal Investigator

Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

William Edward Richards
Ph: 800-622-6877

William Edward Richards
Principal Investigator

Low Country Cancer Care Associates PC

James Joseph Burke
Ph: 912-350-8568

James Joseph Burke
Principal Investigator

Memorial University Medical Center

James Joseph Burke
Ph: 912-350-8568

James Joseph Burke
Principal Investigator

Summit Cancer Care-Memorial

James Joseph Burke
Ph: 912-350-8568

James Joseph Burke
Principal Investigator

Hawaii
Honolulu

Queen's Medical Center

Michael Ethan Carney
Ph: 808-983-6090

Michael Ethan Carney
Principal Investigator

Idaho
Boise

Saint Alphonsus Cancer Care Center-Boise

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Illinois
Bloomington

Illinois CancerCare-Bloomington

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Saint Joseph Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Canton

Illinois CancerCare-Canton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carbondale

Memorial Hospital of Carbondale

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carthage

Illinois CancerCare-Carthage

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Centralia

Centralia Oncology Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Decatur

Cancer Care Center of Decatur

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Decatur Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Effingham

Crossroads Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Eureka

Illinois CancerCare-Eureka

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Galesburg

Illinois CancerCare Galesburg

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Western Illinois Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Hinsdale

Sudarshan K Sharma MD Limted-Gynecologic Oncology

Sudarshan K. Sharma
Ph: 630-856-6757

Sudarshan K. Sharma
Principal Investigator

Kewanee

Illinois CancerCare-Kewanee Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Macomb

Illinois CancerCare-Macomb

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Mount Vernon

Good Samaritan Regional Health Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Ottawa

Illinois CancerCare-Ottawa Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Radiation Oncology of Northern Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin

Illinois CancerCare-Pekin

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Methodist Medical Center of Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peru

Illinois CancerCare-Peru

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Valley Radiation Oncology

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Princeton

Illinois CancerCare-Princeton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield

Central Illinois Hematology Oncology Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Memorial Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southern Illinois University School of Medicine

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Swansea

Cancer Care Specialists of Illinois-Swansea

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Warrenville

Cadence Cancer Center in Warrenville

LaToya J. Perry
Ph: 630-208-4563
Email: kevin.tomczyk@delnor.com

LaToya J. Perry
Principal Investigator

Indiana
Fort Wayne

Parkview Hospital Randallia

Brian K. Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Brian K. Chang
Principal Investigator

Radiation Oncology Associates PC

Brian K. Chang
Ph: 260-373-8888
Email: parkviewresearch@parkview.com

Brian K. Chang
Principal Investigator

Indianapolis

Indiana University/Melvin and Bren Simon Cancer Center

Jeanne Marie Schilder
Ph: 317-274-2552

Jeanne Marie Schilder
Principal Investigator

Saint Vincent Oncology Center

Gregory P. Sutton
Ph: 574-237-1328

Gregory P. Sutton
Principal Investigator

Richmond

Reid Hospital and Health Care Services

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Iowa
Ames

Mary Greeley Medical Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

McFarland Clinic PC-William R Bliss Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Boone

McFarland Clinic PC-Boone

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Des Moines

Iowa Lutheran Hospital

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Iowa Methodist Medical Center

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Iowa Oncology Research Association CCOP

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Medical Oncology and Hematology Associates-Des Moines

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Fort Dodge

McFarland Clinic PC-Trinity Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Iowa City

University of Iowa/Holden Comprehensive Cancer Center

David Paul Bender
Ph: 800-237-1225

David Paul Bender
Principal Investigator

Jefferson

McFarland Clinic PC-Jefferson

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Marshalltown

McFarland Clinic PC-Marshalltown

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Sioux City

Siouxland Regional Cancer Center

Donald B. Wender
Ph: 712-252-0088

Donald B. Wender
Principal Investigator

West Des Moines

Methodist West Hospital

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Kansas
Kansas City

University of Kansas Cancer Center

Gary Alan Johnson
Ph: 913-945-7552
Email: ctnursenav@kumc.edu

Gary Alan Johnson
Principal Investigator

Kentucky
Crestview Hills

Oncology Hematology Care Inc-Crestview

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Louisiana
Baton Rouge

Mary Bird Perkins Cancer Center

Augusto C. Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Augusto C. Ochoa
Principal Investigator

Woman's Hospital

Giles Fort
Ph: 225-231-5296
Email: Ericka.Seidemann@womans.org

Giles Fort
Principal Investigator

Covington

Mary Bird Cancer Center/Saint Tammany Parish

Augusto C. Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Augusto C. Ochoa
Principal Investigator

New Orleans

Louisiana State University Health Science Center

Augusto C. Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Augusto C. Ochoa
Principal Investigator

Maine
Scarborough

Maine Medical Center- Scarborough Campus

Ian Jared Bristol
Ph: 207-396-8090
Email: wrighd@mmc.org

Ian Jared Bristol
Principal Investigator

Maryland
Baltimore

Greater Baltimore Medical Center

Paul Celano
Ph: 443-849-3706

Paul Celano
Principal Investigator

Bethesda

Walter Reed National Military Medical Center

William J. Lowery
Ph: 301-319-2100

William J. Lowery
Principal Investigator

Silver Spring

Holy Cross Hospital

Sheela Darsani Modin
Ph: 310-754-7552

Sheela Darsani Modin
Principal Investigator

Michigan
Ann Arbor

Saint Joseph Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Dearborn

Oakwood Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Detroit

Saint John Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Flint

Genesys Hurley Cancer Institute

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Hurley Medical Center

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Jackson

Allegiance Health

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Kalamazoo

West Michigan Cancer Center

Sunil Nagpal
Ph: 269-373-7458

Sunil Nagpal
Principal Investigator

Lansing

Sparrow Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Livonia

Saint Mary Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Pontiac

Saint Joseph Mercy Oakland

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Port Huron

Saint Joseph Mercy Port Huron

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Saginaw

Saint Mary's of Michigan

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Southfield

Providence Hospital

Vinay Kumar Malviya
Ph: 248-849-5337
Email: jaswinder.grewal@stjohn.org

Vinay Kumar Malviya
Principal Investigator

Warren

Saint John Macomb-Oakland Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Minnesota
Burnsville

Fairview Ridges Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Coon Rapids

Mercy Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Edina

Fairview-Southdale Hospital

Patrick James Flynn
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Patrick James Flynn
Principal Investigator

Fridley

Unity Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Hutchinson

Hutchinson Area Health Care

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Maplewood

Minnesota Oncology Hematology PA-Maplewood

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Saint John's Hospital - Healtheast

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Minneapolis

Abbott-Northwestern Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Health Partners Inc

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Hennepin County Medical Center

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

New Ulm

New Ulm Medical Center

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Robbinsdale

North Memorial Medical Health Center

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Rochester

Mayo Clinic

Harry J. Long
Ph: 507-538-7623

Harry J. Long
Principal Investigator

Saint Louis Park

Park Nicollet Clinic - Saint Louis Park

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Saint Paul

Regions Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

United Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Shakopee

Saint Francis Regional Medical Center

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Stillwater

Lakeview Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Waconia

Ridgeview Medical Center

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Willmar

Rice Memorial Hospital

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Woodbury

Minnesota Oncology and Hematology PA-Woodbury

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Mississippi
Jackson

University of Mississippi Medical Center

James Tate Thigpen
Ph: 601-815-6700

James Tate Thigpen
Principal Investigator

Pascagoula

Singing River Hospital

James E. Clarkson
Ph: 228-809-5292

James E. Clarkson
Principal Investigator

Missouri
Bolivar

Central Care Cancer Center-Carrie J Babb Cancer Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Bonne Terre

Parkland Health Center-Bonne Terre

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Branson

CoxHealth Cancer Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southeast Cancer Center

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Columbia

University of Missouri - Ellis Fischel

Mark Ira Hunter
Ph: 573-882-7440

Mark Ira Hunter
Principal Investigator

Jefferson City

Capital Region Medical Center-Goldschmidt Cancer Center

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Joplin

Freeman Health System

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Mercy Hospital-Joplin

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Rolla

Phelps County Regional Medical Center

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Saint John's Clinic-Rolla-Cancer and Hematology

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Saint Louis

Mercy Hospital Saint Louis

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Missouri Baptist Medical Center

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Saint Louis Cancer and Breast Institute-South City

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Springfield

CoxHealth South Hospital

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Mercy Hospital Springfield

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Sullivan

Missouri Baptist Sullivan Hospital

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Nebraska
Omaha

Nebraska Methodist Hospital

Peter Craig Morris
Ph: 402-354-7939
Email: kathryn.bartz@nmhs.org

Peter Craig Morris
Principal Investigator

Nevada
Las Vegas

Women's Cancer Center of Nevada

Nicola M. Spirtos
Ph: 702-851-4672

Nicola M. Spirtos
Principal Investigator

New Hampshire
Lebanon

Dartmouth Hitchcock Medical Center

Leslie R. DeMars
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Leslie R. DeMars
Principal Investigator

New Jersey
Basking Ridge

Memorial Sloan Kettering Cancer Center at Basking Ridge

Mario Mendes Leitao
Ph: 212-639-7202

Mario Mendes Leitao
Principal Investigator

Long Branch

Monmouth Medical Center

Mitchell F. Weiss
Ph: 732-923-7689

Mitchell F. Weiss
Principal Investigator

Mount Holly

Fox Chase Cancer Center at Virtua Memorial Hospital of Burlington County

Randolph Bruce Deger
Ph: 888-847-8823

Randolph Bruce Deger
Principal Investigator

Paramus

The Valley Hospital-Luckow Pavilion

Noah A. Goldman
Ph: 201-634-5792

Noah A. Goldman
Principal Investigator

Ridgewood

Valley Hospital

Noah A. Goldman
Ph: 201-634-5792

Noah A. Goldman
Principal Investigator

Vineland

Inspira Medical Center Vineland

Ramakrishna R. Sudhindra
Ph: 856-641-7933

Ramakrishna R. Sudhindra
Principal Investigator

Voorhees

Virtua West Jersey Hospital Voorhees

Randolph Bruce Deger
Ph: 888-847-8823

Randolph Bruce Deger
Principal Investigator

Westwood

Oncology Hematology and Internal Medicine

Noah A. Goldman
Ph: 201-634-5792

Noah A. Goldman
Principal Investigator

Woodbury

Inspira Medical Center Woodbury

Ramakrishna R. Sudhindra
Ph: 856-641-7933

Ramakrishna R. Sudhindra
Principal Investigator

New Mexico
Albuquerque

Southwest Gynecologic Oncology Associates Inc

Carolyn Y. Muller
Ph: 505-272-6972

Carolyn Y. Muller
Principal Investigator

University of New Mexico

Samuel Ryu
Email: sryu1@hfhs.org

Samuel Ryu
Principal Investigator

University of New Mexico Cancer Center

Carolyn Y. Muller
Ph: 505-272-6972

Carolyn Y. Muller
Principal Investigator

Las Cruces

Memorial Medical Center - Las Cruces

Carolyn Y. Muller
Ph: 505-272-6972

Carolyn Y. Muller
Principal Investigator

New York
Albany

Women's Cancer Care Associates LLC

Daniel Casey Kredentser
Ph: 518-458-1390

Daniel Casey Kredentser
Principal Investigator

Bronx

Montefiore Medical Center-Einstein Campus

Mark H. Einstein
Ph: 718-904-2730
Email: aecc@aecom.yu.edu

Mark H. Einstein
Principal Investigator

Brooklyn

State University of New York Downstate Medical Center

Ovadia Abulafia
Ph: 718-270-8216
Email: sima.terebelo@downstate.edu

Ovadia Abulafia
Principal Investigator

The New York Methodist Hospital

Katherine Economos
Ph: 718-780-5240

Katherine Economos
Principal Investigator

Commack

Memorial Sloan Kettering Cancer Center Commack

Mario Mendes Leitao
Ph: 212-639-7202

Mario Mendes Leitao
Principal Investigator

New York

Memorial Sloan-Kettering Cancer Center

Mario Mendes Leitao
Ph: 212-639-7202

Mario Mendes Leitao
Principal Investigator

Rockville Centre

Memorial Sloan-Kettering Cancer Center Rockville Centre

Mario Mendes Leitao
Ph: 212-639-7202

Mario Mendes Leitao
Principal Investigator

Sleepy Hollow

Memorial Sloan-Kettering Cancer Center Sleepy Hollow

Mario Mendes Leitao
Ph: 212-639-7202

Mario Mendes Leitao
Principal Investigator

Stony Brook

Stony Brook University Medical Center

Michael L. Pearl
Ph: 800-862-2215

Michael L. Pearl
Principal Investigator

West Harrison

Memorial Sloan-Kettering Cancer Center West Harrison

Mario Mendes Leitao
Ph: 212-639-7202

Mario Mendes Leitao
Principal Investigator

North Carolina
Asheboro

Randolph Hospital

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Burlington

Cone Health Cancer Center at Alamance Regional

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Chapel Hill

University of North Carolina at Chapel Hill

Linda Van Le
Ph: 877-668-0683
Email: cancerclinicaltrials@med.unc.edu

Linda Van Le
Principal Investigator

Charlotte

Novant Health Presbyterian Medical Center

John Matthew McDonald
Ph: 704-384-5369

John Matthew McDonald
Principal Investigator

Clinton

Southeastern Medical Oncology Center-Clinton

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Goldsboro

Southeastern Medical Oncology Center-Goldsboro

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Wayne Memorial Hospital

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Greensboro

Cone Health Cancer Center

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Jacksonville

Onslow Memorial Hospital

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Southeastern Medical Oncology Center-Jacksonville

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Mebane

Cone Heath Cancer Center at Mebane

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Reidsville

Annie Penn Memorial Hospital

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Wilson

Southeastern Medical Oncology Center-Wilson

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Winston-Salem

Wake Forest University Health Sciences

Samuel Smith Lentz
Ph: 336-713-6771

Samuel Smith Lentz
Principal Investigator

Ohio
Akron

Summa Akron City Hospital/Cooper Cancer Center

Vivian E. von Gruenigen
Ph: 330-375-6101

Vivian E. von Gruenigen
Principal Investigator

Belpre

Strecker Cancer Center-Belpre

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Centerville

Miami Valley Hospital South

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Chillicothe

Adena Regional Medical Center

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Cincinnati

Oncology Hematology Care Inc - Anderson

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Oncology Hematology Care Inc - Kenwood

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Oncology Hematology Care Inc-Blue Ash

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Oncology Hematology Care Inc-Eden Park

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Oncology Hematology Care Inc-Mercy West

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

University of Cincinnati

Eric Lawrence Eisenhauer
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Eric Lawrence Eisenhauer
Principal Investigator

Cleveland

Case Western Reserve University

Steven E. Waggoner
Ph: 800-641-2422

Steven E. Waggoner
Principal Investigator

Cleveland Clinic Cancer Center/Fairview Hospital

Peter G. Rose
Ph: 866-223-8100

Peter G. Rose
Principal Investigator

Cleveland Clinic Foundation

Peter G. Rose
Ph: 866-223-8100

Peter G. Rose
Principal Investigator

Columbus

Columbus Oncology and Hematology Associates Inc

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Doctors Hospital

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Grant Medical Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Mount Carmel East Hospital

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Mount Carmel Health Center West

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Ohio State University Comprehensive Cancer Center

David M. O'Malley
Ph: 800-293-5066
Email: Jamesline@osumc.edu

David M. O'Malley
Principal Investigator

Riverside Methodist Hospital

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

The Mark H Zangmeister Center

John Philip Kuebler
Ph: 502-361-8496

John Philip Kuebler
Principal Investigator

Dayton

Good Samaritan Hospital - Dayton

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Miami Valley Hospital

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Samaritan North Health Center

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Delaware

Delaware Health Center-Grady Cancer Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Delaware Radiation Oncology

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Grady Memorial Hospital

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Fairfield

Oncology Hematology Care Inc-Healthplex

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Findlay

Blanchard Valley Hospital

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Franklin

Atrium Medical Center-Middletown Regional Hospital

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Greenville

Wayne Hospital

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Kettering

Kettering Medical Center

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Lancaster

Fairfield Medical Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Marietta

Marietta Memorial Hospital

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Marion

OneHealth Marion General Hospital

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Mayfield Heights

Hillcrest Hospital Cancer Center

Peter G. Rose
Ph: 866-223-8100

Peter G. Rose
Principal Investigator

Mentor

Lake University Ireland Cancer Center

Steven E. Waggoner
Ph: 800-641-2422

Steven E. Waggoner
Principal Investigator

Mount Vernon

Knox Community Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Newark

Licking Memorial Hospital

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Newark Radiation Oncology

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Portsmouth

Southern Ohio Medical Center

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Springfield

Springfield Regional Cancer Center

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Springfield Regional Medical Center

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Troy

Upper Valley Medical Center

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Westerville

Saint Ann's Hospital

John Philip Kuebler
Ph: 800-446-5532

John Philip Kuebler
Principal Investigator

Zanesville

Genesis HealthCare System

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Oklahoma
Oklahoma City

University of Oklahoma Health Sciences Center

Robert S. Mannel
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Robert S. Mannel
Principal Investigator

Tulsa

Tulsa Cancer Institute

Robert S. Mannel
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Robert S. Mannel
Principal Investigator

Oregon
Clackamas

Clackamas Radiation Oncology Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Providence Oncology and Hematology Care Southeast

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Newberg

Providence Newberg Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Oregon City

Providence Willamette Falls Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Portland

Providence Portland Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Providence Saint Vincent Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Pennsylvania
Abington

Abington Memorial Hospital

Parviz Hanjani
Ph: 215-481-2402

Parviz Hanjani
Principal Investigator

Bethlehem

Saint Luke's University Hospital-Bethlehem Campus

Nicholas P. Taylor
Ph: 610-954-3582
Email: infolink@slhn.org

Nicholas P. Taylor
Principal Investigator

Danville

Geisinger Medical Center

Radhika P. Gogoi
Ph: 570-271-5251

Radhika P. Gogoi
Principal Investigator

Easton

Easton Hospital

Sonyo Shin
Ph: 610-250-4000

Sonyo Shin
Principal Investigator

Philadelphia

Drexel University School of Medicine

Scott Daniel Richard
Ph: 866-884-4484

Scott Daniel Richard
Principal Investigator

Temple University Hospital

Enrique Hernandez
Ph: 215-728-2983

Enrique Hernandez
Principal Investigator

University of Pennsylvania/Abramson Cancer Center

Robert Allen Burger
Ph: 215-746-7406

Robert Allen Burger
Principal Investigator

West Reading

Reading Hospital

Bernice L. Robinson-Bennett
Ph: 610-988-9323

Bernice L. Robinson-Bennett
Principal Investigator

Wilkes-Barre

Geisinger Wyoming Valley/Henry Cancer Center

Radhika P. Gogoi
Ph: 570-271-5251

Radhika P. Gogoi
Principal Investigator

Rhode Island
Providence

Women and Infants Hospital

Carolyn Kay McCourt
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Carolyn Kay McCourt
Principal Investigator

South Carolina
Easley

Greenville Health System Cancer Institute-Easley

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Greenville

Greenville Health System Cancer Institute-Andrews

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Greenville Health System Cancer Institute-Butternut

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Greenville Health System Cancer Institute-Eastside

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Greenville Health System Cancer Institute-Faris

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Greenville Memorial Hospital

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Greer

Greenville Health System Cancer Institute-Greer

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Seneca

Greenville Health System Cancer Institute-Seneca

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

Spartanburg

Greenville Health System Cancer Institute-Spartanburg

Jeffrey W. Elder
Ph: 864-679-3966

Jeffrey W. Elder
Principal Investigator

South Dakota
Rapid City

Black Hills Obstetrics and Gynecology

Helen L. Frederickson
Ph: 605-343-9224

Helen L. Frederickson
Principal Investigator

Rapid City Regional Hospital

Helen L. Frederickson
Ph: 605-343-9224

Helen L. Frederickson
Principal Investigator

Sioux Falls

Avera Cancer Institute

Luis A. Rojas-Espaillat
Ph: 800-657-4377
Email: Jan.Healy@avera.org

Luis A. Rojas-Espaillat
Principal Investigator

Tennessee
Knoxville

University of Tennessee - Knoxville

Larry Clinton Kilgore
Ph: 865-544-9773

Larry Clinton Kilgore
Principal Investigator

Texas
Austin

University Medical Center Brackenridge

Mark Allen Crozier
Ph: 512-324-7991

Mark Allen Crozier
Principal Investigator

Dallas

Parkland Memorial Hospital

David Scott Miller
Ph: 214-648-7097

David Scott Miller
Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

David Scott Miller
Ph: 214-648-7097

David Scott Miller
Principal Investigator

Galveston

University of Texas Medical Branch

Lyuba Levine
Ph: 409-772-1950
Email: clinical.research@utmb.edu

Lyuba Levine
Principal Investigator

Houston

Memorial Hermann Texas Medical Center

Joseph Anthony Lucci
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Joseph Anthony Lucci
Principal Investigator

The Methodist Hospital System

Aparna A. Kamat
Ph: 713-790-2700

Aparna A. Kamat
Principal Investigator

Utah
American Fork

American Fork Hospital / Huntsman Intermountain Cancer Center

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Cedar City

Sandra L Maxwell Cancer Center

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Logan

Logan Regional Hospital

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Murray

Intermountain Medical Center

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Ogden

McKay-Dee Hospital Center

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Provo

Utah Valley Regional Medical Center

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Saint George

Dixie Medical Center Regional Cancer Center

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Salt Lake City

Huntsman Cancer Institute/University of Utah

Matthew M. Poppe
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Matthew M. Poppe
Principal Investigator

LDS Hospital

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Utah Cancer Specialists-Salt Lake City

R. Jeffrey Lee
Ph: 801-507-3950

R. Jeffrey Lee
Principal Investigator

Virginia
Portsmouth

Naval Medical Center - Portsmouth

Edward F. Miles
Ph: 757-953-5939

Edward F. Miles
Principal Investigator

Washington
Auburn

MultiCare Auburn Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Bainbridge Island

Virginia Mason Bainbridge Island Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Bellevue

Overlake Hospital Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Federal Way

Virginia Mason Federal Way Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Gig Harbor

MultiCare Gig Harbor Medical Park

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Gig Harbor

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Kennewick

Kadlec Clinic Hematology and Oncology

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Northwest Cancer Clinic

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tri-Cities Cancer Center

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Kirkland

EvergreenHealth Medical Center

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Seattle Cancer Care Alliance at EvergreenHealth

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Longview

Saint John Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Lynnwood

Virginia Mason Lynnwood Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Mount Vernon

Skagit Valley Hospital

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Skagit Valley Hospital Regional Cancer Care Center

Benjamin E. Greer
Ph: 206-616-8289

Benjamin E. Greer
Principal Investigator

Port Angeles

Olympic Medical Center

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Poulsbo

Peninsula Cancer Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Puyallup

MultiCare Good Samaritan Hospital

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Puyallup

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Seattle

Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Northwest Hospital

Benjamin E. Greer
Ph: 206-616-8289

Benjamin E. Greer
Principal Investigator

Seattle Cancer Care Alliance

Benjamin E. Greer
Ph: 206-616-8289

Benjamin E. Greer
Principal Investigator

University of Washington Medical Center

Benjamin E. Greer
Ph: 206-616-8289

Benjamin E. Greer
Principal Investigator

Virginia Mason Medical Center

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Women's Cancer Center of Seattle

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Sequim

Olympic Medical Cancer Care Center

Benjamin E. Greer
Ph: 206-616-8289

Benjamin E. Greer
Principal Investigator

Spokane

Cancer Care Northwest - Spokane South

Benjamin E. Greer
Ph: 206-616-8289

Benjamin E. Greer
Principal Investigator

Cancer Care Northwest-North Spokane

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Cancer Care Northwest-Valley

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

Tacoma

Multicare Health System

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Jackson Hall

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Tacoma/Valley Radiation Oncology Centers-Saint Joe's

John A. Keech
Ph: 907-458-5380

John A. Keech
Principal Investigator

Vancouver

PeaceHealth Southwest Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Wenatchee

Wenatchee Valley Hospital and Clinics

Heidi Joy Gray
Ph: 206-616-8289

Heidi Joy Gray
Principal Investigator

West Virginia
Wheeling

Wheeling Hospital/Schiffler Cancer Center

Jondavid Pollock
Ph: 304-243-6442

Jondavid Pollock
Principal Investigator

Wisconsin
Fond Du Lac

Aurora Health Center-Fond du Lac

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Green Bay

Aurora BayCare Medical Center

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Saint Vincent Hospital

Jonathan Edward Tammela
Ph: 920-433-8889

Jonathan Edward Tammela
Principal Investigator

La Crosse

Gundersen Lutheran Medical Center

Kurt Oettel
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Kurt Oettel
Principal Investigator

Marinette

Vince Lombardi Cancer Clinic-Marinette

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Milwaukee

Aurora Saint Luke's Medical Center

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Froedtert and the Medical College of Wisconsin

William H. Bradley
Ph: 414-805-4380

William H. Bradley
Principal Investigator

New Richmond

Cancer Center of Western Wisconsin

Matthew P. Boente
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Matthew P. Boente
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Sheboygan

Vince Lombardi Cancer Clinic-Sheboygan

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Summit

Aurora Medical Center in Summit

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Two Rivers

Vince Lombardi Cancer Clinic

Ali Mahdavi
Ph: 414-649-5717

Ali Mahdavi
Principal Investigator

Wyoming
Cheyenne

Cheyenne Regional Medical Center-West

Keren Sturtz
Ph: 888-785-6789

Keren Sturtz
Principal Investigator

Japan

Kagoshima City

Kagoshima City Hospital

Toshiaki Nakamura
Ph: 011 81 099 224 2101

Toshiaki Nakamura
Principal Investigator

Kure

Kure National Hospital

Takashi Sawasaki
Ph: (0823) 22-3111

Takashi Sawasaki
Principal Investigator

Matsuyama

Shikoku Cancer Center

Kazuhiro Takehara
Ph: 089-999-1172

Kazuhiro Takehara
Principal Investigator

Morioka

Iwate Medical University School of Medicine

Toru Sugiyama
Ph: 019-651-5111

Toru Sugiyama
Principal Investigator

Niigata City

Niigata University Medical and Dental Hospital

Takayuki Enomoto
Ph: 81-025-223-6161

Takayuki Enomoto
Principal Investigator

Osaka, Osaka

Kinki University

Masaki Mandai
Ph: 072-366-0221

Masaki Mandai
Principal Investigator

Sendai

Tohoku University School of Medicine

Nobuo Yaegashi
Email: med-som@bureau.tohoku.ac.jp

Nobuo Yaegashi
Principal Investigator

Republic of Korea

Goyang-si

National Cancer Center-Korea

Sang Yoon Park
Ph: 011-82-760-2384

Sang Yoon Park
Principal Investigator

Jung-Ku

Keimyung University-Dongsan Medical Center

Chi-Heum Cho
Email: ho@dsmc.or.kr

Chi-Heum Cho
Principal Investigator

Seongnam City

Seoul National University Bundang Hospital

Kidong Kim
Ph: 011-82-760-2384

Kidong Kim
Principal Investigator

Seoul

Asan Medical Center

Young-Tak Kim
Email: irbksh@amc.seoul.kr

Young-Tak Kim
Principal Investigator

Gangnam Severance Hospital

Jae-Hoon Kim
Email: clinical.trial@bms.com

Jae-Hoon Kim
Principal Investigator

Korea Cancer Center Hospital

Beob-Jong Kim
Ph: 011-82-02-9702-114

Beob-Jong Kim
Principal Investigator

Seoul National University Hospital

Jae Weon Kim
Ph: 011-82-760-2384

Jae Weon Kim
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01101451

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.