Diet in Altering Disease Progression in Patients With Prostate Cancer on Active Surveillance

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
No phase specifiedBiomarker/Laboratory analysis, TreatmentActive50 to 80NCI, OtherCDR0000687958
CALGB-70807, NCT01238172

Trial Description

Summary

RATIONALE: Eating a diet high in vegetables may slow down disease progression in patients with prostate cancer.

PURPOSE: This randomized clinical trial is studying how well diet works in altering disease progression in patients with prostate cancer on active surveillance.

Further Study Information

OBJECTIVES:

Primary

  • To determine if a telephone-based dietary intervention compared to no intervention will decrease clinical progression in AS patients.

Secondary

  • To compare the incidence of active treatment (surgery, irradiation, local ablation, or androgen deprivation) in AS patients receiving dietary intervention compared to no intervention.
  • To compare prostate cancer-related anxiety in AS patients receiving dietary intervention compared to no intervention.
  • To compare health-related quality of life in AS patients receiving dietary intervention compared to no intervention.

OUTLINE: This is a multicenter study. Patients are stratified according to age (≤ 70 years vs > 70 years), race (African American vs other), and time of baseline prostate biopsy (0-12 months before registration vs > 12-24 months before registration). Patients are randomized to 1 of 2 treatment arms.

  • Arm I: Patients receive the MEAL program intervention with dietary education and telephone counseling sessions for 24 months. Patients receive the "Participant Notebook", which provides written material describing the counseling program. It also outlines the dietary targets, offers supporting information on strategies to achieve these targets, supplies referent tools to help patients accurately estimate servings of target foods, and offers recipes and articles about diet and prostate cancer. The counseling sessions are divided into 4 phases, with the first three phases completed in 7 months and the fourth phase continuing for 17 months. The first phase comprises 6 counseling calls focusing on education and the rapid development of self-efficacy, the second phase comprises 4 calls over a 2-month period focusing on practical and consistent implementation of the dietary pattern, the third phase comprises 4 calls over a 4-month period helping patients habituate to the dietary pattern by providing regular performance reviews, and the fourth phase comprises 8 calls over a 17-month period and is a maintenance phase. Patients are encouraged to achieve 7 servings per day of vegetables (2 cruciferous, 2 tomato products, 3 other vegetables), 2 servings per day of whole grains, 1 serving per day of beans or other legumes, and 2 servings per day of fruit. Patients also receive 8 regularly scheduled newsletters over the course of 24 months. The newsletters focus on study goals and progress and provide tips on achieving and maintaining diet change. They also include information on diet and cancer, the challenges of diet change, the advances in prostate cancer control, and new recipes.
  • Arm II: Patients receive standard United States Department of Agriculture dietary guidelines for Americans. Patients also receive 8 regularly scheduled newsletters over the course of 24 months. The newsletters contain general information about diet and healthy lifestyle.

Blood (plasma and serum) and tissue samples are collected at baseline and at 12 and 24 months for biomarker and pharmacogenomic studies.

Patients complete quality-of-life assessments (Personal Habits Questionnaire, Functional Assessment of Cancer Therapy Scale-Prostate (FACT-P), Memorial Anxiety Scare for Prostate Cancer (Max-PC), International Prostate Symptom Score (IPSS), Expanded Prostate Cancer Index Composite 26 (EPIC-26), and Nutrition Self-Efficacy and Satisfaction with the MEAL Program) at baseline and at 6, 12, 18, and 24 months.

After study entry, patients are followed up every 3 months for 2 years.

Eligibility Criteria

DISEASE CHARACTERISTICS:

  • Biopsy-proven (consisting of ≥ 10 tissue cores) adenocarcinoma of the prostate diagnosed within 24 months prior to presentation
  • < 25% of biopsy tissue cores positive for cancer
  • ≤ 50% of any one biopsy tissue core positive for cancer
  • Clinical stage ≤ T2a
  • Patients who have prostate cancer with distant metastases are not eligible
  • For men ≤ 70 years, biopsy Gleason score ≤ 6; for men > 70 years, biopsy Gleason score ≤ (3 + 4) = 7
  • Serum PSA < 10 ng/mL
  • Baseline PSA for determination of eligibility must be measured after discontinuation of any 5-alpha reductase inhibitors
  • Patients are offered registration to the correlative study CALGB-151105

PATIENT CHARACTERISTICS:

  • Life expectancy of at least 3 years
  • Patients must be able to read and comprehend English language text and be able to understand spoken English over the phone
  • Patients who have had a history of non-cutaneous malignancy (other than nonmelanoma skin cancer) in the previous 5 years are not eligible
  • Successful completion of three 24-hour dietary recalls during the run-in period

PRIOR CONCURRENT THERAPY:

  • Patients who have had prior treatment for prostate cancer by surgery, irradiation, local ablative (i.e., cryosurgery or high-intensity focused ultrasound), or androgen-deprivation therapy are not eligible
  • Patients who are currently taking vitamin supplements including lycopene and beta-carotene are eligible
  • Patients who are currently taking coumadin are not eligible
  • Patients consuming ≥ 6 servings per day of fruits and vegetables (not including juices), as measured by the run-in dietary recalls, are not eligible
  • Patients receiving treatment with 5-alpha reductase inhibitors within 90 days prior to preregistration are not eligible

Trial Contact Information

Trial Lead Organizations/Sponsors

Alliance for Clinical Trials in Oncology

  • National Cancer Institute
J. Kellogg Parsons, MD, MHS, Study Chair
James Marshall, Study Chair

Trial Sites

U.S.A.

Alaska
Fairbanks

Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital

Craig R. Nichols
Ph: 503-215-6412
Email: vmmc.cancer_clinical_research@VirginiaMason.org

California
Concord

Cancer Care Center at John Muir Health - Concord Campus

Kenneth C Hsiao
Ph: 925-674-2580

La Jolla

Rebecca and John Moores UCSD Cancer Center

J. Kellogg Parsons

Loma Linda

Loma Linda University Cancer Institute at Loma Linda University Medical Center

Herbert C Ruckle
Ph: 909-558-3375

Los Angeles

Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai Medical Center

Hyung L Kim
Ph: 310-423-8965

Orange

Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center

Edward M Uchio
Ph: 877-827-8839
Email: ucstudy@uci.edu

San Diego

Naval Medical Center - San Diego

Sean P Stroup
Ph: 619-532-8712

San Francisco

UCSF Helen Diller Family Comprehensive Cancer Center

Maxwell V Meng
Ph: 877-827-3222

Walnut Creek

John Muir/Mt. Diablo Comprehensive Cancer Center

Kenneth C Hsiao
Ph: 925-674-2580

Colorado
Aurora

University of Colorado Cancer Center at UC Health Sciences Center

Paul D Maroni
Ph: 720-848-0650

Fort Collins

Poudre Valley Hospital

Regina J Brown
Ph: 970-297-6150

Glenwood Springs

Valley View Hospital Cancer Center

Paul D Maroni
Ph: 720-848-0650

Connecticut
Hartford

Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Middletown

Middlesex Hospital Cancer Center

Susanna Hong
Ph: 860-358-2058

West Haven

Veterans Affairs Medical Center - West Haven

Charles N Walker
Ph: 203-937-3421ext2832

Delaware
Lewes

Tunnell Cancer Center at Beebe Medical Center

Stephen Scott Grubbs
Ph: 302-733-6227

Newark

Christiana Gynecologic Oncology, LLC

Stephen Scott Grubbs
Ph: 302-733-6227

Delaware Clinical and Laboratory Physicians

Stephen Scott Grubbs
Ph: 302-733-6227

Helen F. Graham Cancer Center at Christiana Hospital

Stephen Scott Grubbs
Ph: 302-733-6227

Stephen Scott Grubbs
Ph: 302-733-6227

Medical Oncology Hematology Consultants, PA at Helen F. Graham Cancer Center

Stephen Scott Grubbs
Ph: 302-733-6227

Regional Hematology/Oncology, PA - Newark

Stephen Scott Grubbs
Ph: 302-733-6227

Rehoboth Beach

Beebe Health Campus

Stephen Scott Grubbs
Ph: 302-733-6227

Seaford

Nanticoke Memorial Hospital

Stephen Scott Grubbs
Ph: 302-733-6227

Wilmington

Christiana Care Health System-Wilmington Hospital

Stephen Scott Grubbs
Ph: 302-733-6227

Florida
Lakeland

Lakeland Regional Cancer Center at Lakeland Regional Medical Center

Gameel B Hodge
Ph: 863-904-1900

Weston

Cleveland Clinic Florida - Weston

Nicolas A Muruve
Ph: 954-659-5705

Georgia
Albany

Phoebe Cancer Center at Phoebe Putney Memorial Hospital

Chirag R Jani
Ph: 229-312-2251

Atlanta

CCOP - Atlanta Regional

Thomas E. Seay
Ph: 404-303-3355

Northside Hospital Cancer Center

Thomas E. Seay
Ph: 404-303-3355

Piedmont Hospital

Thomas E. Seay
Ph: 404-303-3355

Saint Joseph's Hospital of Atlanta

Thomas E. Seay
Ph: 404-303-3355

Austell

WellStar Cobb Hospital

Thomas E. Seay
Ph: 404-303-3355

Columbus

John B. Amos Cancer Center

Thomas E. Seay
Ph: 404-303-3355

Decatur

Charles B. Eberhart Cancer Center at DeKalb Medical Center

Thomas E. Seay
Ph: 404-303-3355

Fayetteville

Piedmont Fayette Hospital

Thomas E. Seay
Ph: 404-303-3355

Lawrenceville

Gwinnett Medical Center

Thomas E. Seay
Ph: 404-303-3355

Marietta

Kennestone Cancer Center at Wellstar Kennestone Hospital

Thomas E. Seay
Ph: 404-303-3355

Riverdale

Southern Regional Medical Center

Thomas E. Seay
Ph: 404-303-3355

Rome

Harbin Clinic Cancer Center - Medical Oncology

Thomas E. Seay
Ph: 404-303-3355

Hawaii
Aiea

Kapiolani Medical Center at Pali Momi

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Ph: 808-586-2979

Honolulu

Cancer Research Center of Hawaii

Jeffrey L. Berenberg
Ph: 808-586-2979

Kapiolani Medical Center for Women and Children

Jeffrey L. Berenberg
Ph: 808-586-2979

OnCare Hawaii, Incorporated - Kuakini

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Ph: 808-586-2979

OnCare Hawaii, Incorporated - Lusitana

Jeffrey L. Berenberg
Ph: 808-586-2979

Queen's Cancer Institute at Queen's Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Straub Clinic and Hospital, Incorporated

Jeffrey L. Berenberg
Ph: 808-586-2979

Lihue

Kauai Medical Clinic

Jeffrey L. Berenberg
Ph: 808-586-2979

Idaho
Boise

Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Philip J. Stella
Ph: 734-712-4673

Coeur D'Alene

Kootenai Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Lewiston

St. Joseph Regional Medical Center

John A Keech
Ph: 907-458-5380

Post Falls

Kootenai Cancer Center - Post Falls

Benjamin Thomas Marchello
Ph: 800-648-6274

Sandpoint

Kootenai Cancer

Benjamin Thomas Marchello
Ph: 800-648-6274

Illinois
Bloomington

Illinois CancerCare - Bloomington

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

St. Joseph Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Canton

Illinois CancerCare - Canton

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Carbondale

Memorial Hospital of Carbondale

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Carthage

Illinois CancerCare - Carthage

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Centralia

Centralia Oncology Clinic

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Chicago

Louis A. Weiss Memorial Hospital

Keith L. Shulman
Ph: 773-564-5044

Resurrection Medical Center

James P Brown
Ph: 773-792-5116

University of Chicago Cancer Research Center

Scott E Eggener
Ph: 773-834-7424

Danville

Carle on Vermilion

Vamsi K Vasireddy
Ph: 800-446-5532

Decatur

Cancer Care Center of Decatur

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Decatur Memorial Hospital Cancer Care Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Effingham

Carle Physician Group-Effingham

Vamsi K Vasireddy
Ph: 800-446-5532

Crossroads Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Eureka

Illinois CancerCare - Eureka

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Galesburg

Galesburg Clinic, PC

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

InterCommunity Cancer Center of Western Illinois

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Hines

Veterans Affairs Medical Center - Hines

Nirmala Bhoopalam
Ph: 708-202-8387

Kewanee

Illinois CancerCare - Kewanee Clinic

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Macomb

Illinois CancerCare - Macomb

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Mattoon

Carle Physician Group-Mattoon/Charleston

Vamsi K Vasireddy
Ph: 800-446-5532

Ottawa

Illinois CancerCare - Ottawa

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Radiation Oncology of Northern Illinois

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Pekin

Cancer Treatment Center at Pekin Hospital

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Illinois CancerCare - Pekin

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Peoria

Illinois CancerCare - Peoria

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Methodist Medical Center of Illinois

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

OSF St. Francis Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Peru

Illinois CancerCare - Princeton

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Valley Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Princeton

Illinois CancerCare - Princeton

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

River Forest

West Suburban Center for Cancer Care

Isoken Koko
Ph: 708-488-0882

Springfield

Central Illinois Hematology Oncology Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Regional Cancer Center at Memorial Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Simmons Cooper Cancer Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Springfield Clinic - Main Campus

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Urbana

Carle Cancer Center at Carle Foundation Hospital

Vamsi K Vasireddy
Ph: 800-446-5532

Vamsi K Vasireddy
Ph: 800-446-5532

Indiana
Elkhart

Michiana Hematology-Oncology, PC - Elkhart

Rafat H. Ansari
Ph: 574-234-5123

Michigan City

Saint Anthony Memorial Health Centers

Vamsi K Vasireddy
Ph: 800-446-5532

Woodland Cancer Care Center

Vamsi K Vasireddy
Ph: 800-446-5532

Mishawaka

Michiana Hematology-Oncology, PC - Mishawaka

Rafat H. Ansari
Ph: 574-234-5123

Saint Joseph's Medical Center

Rafat H. Ansari
Ph: 574-234-5123

Plymouth

Michiana Hematology Oncology PC - Plymouth

Rafat H. Ansari
Ph: 574-234-5123

South Bend

CCOP - Northern Indiana CR Consortium

Rafat H. Ansari
Ph: 574-234-5123

Michiana Hematology-Oncology, PC - South Bend

Rafat H. Ansari
Ph: 574-234-5123

Westville

Michiana Hematology Oncology-PC Westville

Rafat H. Ansari
Ph: 574-234-5123

Iowa
Ames

McFarland Clinic, PC

Joseph James Merchant
Ph: 515-239-2621

William R. Bliss Cancer Center at Mary Greeley Medical Center

Joseph James Merchant
Ph: 515-239-2621

Boone

McFarland Clinic PC-Boone

Joseph James Merchant
Ph: 515-239-2621

Fort Dodge

Trinity Regional Medical Center

Joseph James Merchant
Ph: 515-239-2621

Jefferson

McFarland Clinic PC-Jefferson

Joseph James Merchant
Ph: 515-239-2621

Marshalltown

McFarland Clinic PC-Marshalltown

Joseph James Merchant
Ph: 515-239-2621

Kansas
Emporia

Newman Regional Health

Peter J. VanVeldhuizen
Ph: 800-525-1483

Garden City

St. Catherine Hospital Cancer Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Great Bend

St. Rose Ambulatory and Surgery Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Hays

Hays Medical Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Kansas City

Kansas City Cancer Centers - West

Peter J. VanVeldhuizen
Ph: 800-525-1483

Kansas Masonic Cancer Research Institute at the University of Kansas Medical Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Olathe

Olathe Medical Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Overland Park

Kansas City Cancer Centers - Southwest

Peter J. VanVeldhuizen
Ph: 800-525-1483

Pittsburg

Mount Carmel Regional Cancer Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Salina

Tammy Walker Cancer Center at Salina Regional Health Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Topeka

Cotton-O'Neil Cancer Center

David E Einspahr
Ph: 785-270-4963

St. Francis Comprehensive Cancer Center

Peter J. VanVeldhuizen
Ph: 800-525-1483

Louisiana
Baton Rouge

Mary Bird Perkins Cancer Center - Baton Rouge

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

New Orleans

Medical Center of Louisiana - New Orleans

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Stanley S. Scott Cancer Center at Louisiana State University Medical Center - New Orleans

Augusto C Ochoa
Ph: 504-568-2428
Email: emede1@lsuhsc.edu

Maine
Portland

Maine Medical Center - Bramhall Campus

Matthew H Hayn
Ph: 207-396-8377

Scarborough

Maine Medical Center- Scarborough Campus

Matthew H Hayn
Ph: 207-396-8377

York

York Hospital's Oncology Treatment Center

Jonathan D Eneman
Ph: 207-351-3777

Maryland
Bethesda

National Naval Medical Center

David C Van Echo
Ph: 301-319-2100

Massachusetts
Boston

Beth Israel Deaconess Medical Center

Adam Stuart Kibel
Ph: 617-724-5200

Dana-Farber/Brigham and Women's Cancer Center

Adam Stuart Kibel
Ph: 617-724-5200

Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute

Adam Stuart Kibel
Ph: 617-724-5200

Hyannis

Davenport-Mugar Cancer Center at Cape Cod Hospital

Kelly M Swanson
Ph: 508-862-5799

Michigan
Adrian

Hickman Cancer Center at Bixby Medical Center

Rex B Mowat
Ph: 800-444-3561

Ann Arbor

Saint Joseph Mercy Cancer Center

Philip J. Stella
Ph: 734-712-4673

Battle Creek

Battle Creek Health System Cancer Care Center

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Dearborn

Oakwood Cancer Center at Oakwood Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Detroit

Van Elslander Cancer Center at St. John Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Flint

Genesys Hurley Cancer Institute

Philip J. Stella
Ph: 734-712-4673

Hurley Medical Center

Philip J. Stella
Ph: 734-712-4673

Grand Rapids

Butterworth Hospital at Spectrum Health

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Lacks Cancer Center at Saint Mary's Health Care

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Jackson

Gayle M. Jacob Cancer Center at Allegiance Health

Philip J. Stella
Ph: 734-712-4673

Kalamazoo

Borgess Medical Center

Raymond Sterling Lord
Ph: 269-373-7458

Bronson Methodist Hospital

Raymond Sterling Lord
Ph: 269-373-7458

West Michigan Cancer Center

Raymond Sterling Lord
Ph: 269-373-7458

Lansing

Sparrow Regional Cancer Center

Philip J. Stella
Ph: 734-712-4673

Livonia

St. Mary Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Monroe

Community Cancer Center of Monroe

Rex B Mowat
Ph: 800-444-3561

Muskegon

Mercy General Health Partners

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Niles

Lakeland Hospital - Niles

Rafat H. Ansari
Ph: 574-234-5123

Pontiac

St. Joseph Mercy Oakland

Philip J. Stella
Ph: 734-712-4673

Port Huron

Mercy Regional Cancer Center at Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Reed City

Spectrum Health Reed City Hospital

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Royal Oak

William Beaumont Hospital - Royal Oak Campus

Howard J. Korman
Ph: 248-551-7695

Saginaw

Seton Cancer Institute at Saint Mary's - Saginaw

Philip J. Stella
Ph: 734-712-4673

Saint Joseph

Lakeside Cancer Specialists, PLLC

Rafat H. Ansari
Ph: 574-234-5123

St. Joseph

Lakeland Regional Cancer Care Center - St. Joseph

Rafat H. Ansari
Ph: 574-234-5123

Traverse City

Munson Medical Center

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Troy

William Beaumont Hospital - Troy Campus

Howard J. Korman
Ph: 248-551-7695

Warren

St. John Macomb Hospital

Philip J. Stella
Ph: 734-712-4673

Minnesota
Saint Cloud

CentraCare Clinic - Women and Children

Donald J Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Coborn Cancer Center

Donald J Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Sartell

Adult and Pediatric Urology, PLLP

Donald J Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Missouri
Bonne Terre

Parkland Health Center-Bonne Terre

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Cape Girardeau

Saint Francis Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Southeast Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Columbia

Veterans Affairs Medical Center - Columbia (Truman Memorial)

Shadi M Haddadin
Ph: 888-823-5923
Email: ctsucontact@westat.com

Jefferson City

Goldschmidt Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Kansas City

Kansas City Cancer Centers - North

Peter J. VanVeldhuizen
Ph: 800-525-1483

Kansas City Cancer Centers - South

Peter J. VanVeldhuizen
Ph: 800-525-1483

Truman Medical Center - Hospital Hill

Peter J. VanVeldhuizen
Ph: 800-525-1483

Veterans Affairs Medical Center - Kansas City

Peter J. VanVeldhuizen
Ph: 800-525-1483

Lee's Summit

Kansas City Cancer Centers - East

Peter J. VanVeldhuizen
Ph: 800-525-1483

Saint Louis

Barnes-Jewish West County Hospital

Seth A Strope
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Missouri Baptist Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

Seth A Strope
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Saint Peters

Siteman Cancer Center at Barnes-Jewish St. Peters Hospital - St. Peters

Seth A Strope
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Sullivan

Missouri Baptist Sullivan Hospital

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Montana
Billings

Billings Clinic Cancer Center - 801 N 29th Street

Benjamin Thomas Marchello
Ph: 800-648-6274

CCOP - Montana Cancer Consortium

Benjamin Thomas Marchello
Ph: 800-648-6274

St. Vincent Healthcare Cancer Care Services

Benjamin Thomas Marchello
Ph: 800-648-6274

Bozeman

Bozeman Deaconess Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Butte

St. James Healthcare Cancer Care

Benjamin Thomas Marchello
Ph: 800-648-6274

Great Falls

Benefis Sletten Cancer Institute

Benjamin Thomas Marchello
Ph: 800-648-6274

Helena

St. Peter's Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Kalispell

Kalispell Regional Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Missoula

Community Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Nevada
Henderson

21st Century Oncology - Henderson

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada-Southeast Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center - Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas

21st Century Oncology - Fort Apache

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Sunrise

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Fort Apache

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Shadow

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer Institute of Nevada at Summerlin Hospital Medical Center

John Allan Ellerton
Ph: 702-384-0013

Cancer Therapy and Integrative Medicine

John Allan Ellerton
Ph: 702-384-0013

CCOP - Nevada Cancer Research Foundation

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Northwest

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Southwest

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center-Medical Center

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Downtown Location

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Eastern Location

John Allan Ellerton
Ph: 702-384-0013

University Medical Center of Southern Nevada

John Allan Ellerton
Ph: 702-384-0013

New Hampshire
Manchester

Elliot Regional Cancer Center at Elliot Hospital

Brian R Knab
Ph: 603-663-1800

New Jersey
Camden

Cancer Institute of New Jersey at Cooper University Hospital - Camden

Robert A Somer
Ph: 856-325-6757

Englewood

Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center

Eric J Margolis
Ph: 201-816-1900

Somerville

Somerset Medical Center

Dhiren S Dave
Ph: 908-927-0300

Voorhees

Cancer Institute of New Jersey at Cooper - Voorhees

Robert A Somer
Ph: 856-325-6757

New York
Bay Shore

Southside Hospital

Manish A Vira
Ph: 516-562-3467

Brooklyn

Maimonides Cancer Center at Maimonides Medical Center

David A Silver
Ph: 718-765-2500

Buffalo

Veterans Affairs Medical Center - Buffalo

Lynn Marie Steinbrenner
Ph: 716-862-3191

Glens Falls

Charles R. Wood Cancer Center at Glens Falls Hospital

Aqeel A Gillani
Ph: 518-926-6700

Manhasset

Don Monti Comprehensive Cancer Center at North Shore University Hospital

Manish A Vira
Ph: 516-562-3467

Middletown

Tucker Center for Cancer Care at Orange Regional Medical Center

Jeffrey M. Stewart
Ph: 845-342-7609

New Hyde Park

Long Island Jewish Medical Center

Manish A Vira
Ph: 516-562-3467

Monter Cancer Center of the North Shore-LIJ Health System

Manish A Vira
Ph: 516-562-3467

Rochester

James P. Wilmot Cancer Center at University of Rochester Medical Center

Jonathan W Friedberg
Ph: 585-275-5830

Stony Brook

Stony Brook University Cancer Center

Howard L Adler
Ph: 800-862-2215

North Carolina
Chapel Hill

Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill

Michael E Woods
Ph: 877-668-0683
Email: cancerclinicaltrials@med.unc.edu

High Point

High Point Regional Hospital

M. Craig Hall
Ph: 336-687-1451

Ohio
Akron

McDowell Cancer Center at Akron General Medical Center

Esther H. Rehmus
Ph: 330-344-6348

Cincinnati

Christ Hospital Cancer Center

Brian A Mannion
Ph: 513-585-2859

Maumee

Northwest Ohio Oncology Center

Rex B Mowat
Ph: 800-444-3561

Rex B Mowat
Ph: 800-444-3561

Oregon

St. Charles Mercy Hospital

Rex B Mowat
Ph: 800-444-3561

Sylvania

Flower Hospital Cancer Center

Rex B Mowat
Ph: 800-444-3561

Toledo

CCOP - Toledo Community Hospital

Rex B Mowat
Ph: 800-444-3561

St. Anne Mercy Hospital

Rex B Mowat
Ph: 800-444-3561

Toledo Clinic, Incorporated - Main Clinic

Rex B Mowat
Ph: 800-444-3561

University of Toledo Medical Center

Rex B Mowat
Ph: 800-444-3561

Oklahoma
Oklahoma City

Stephenson Cancer Center at the University of Oklahoma

Sindhu Singh
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Tulsa

Cancer Care Associates-Yale

Sindhu Singh
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Oregon
Coos Bay

Bay Area Hospital

Leo Kusuda
Ph: 541-269-8392
Email: cherie.cox@bayareahospital.org

Pennsylvania
Allentown

Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest

Suresh G. Nair
Ph: 610-402-2273

Bethlehem

Lehigh Valley Hospital - Muhlenberg

Suresh G. Nair
Ph: 610-402-2273

Philadelphia

Fox Chase Cancer Center - Philadelphia

Marc C Smaldone
Ph: 215-728-4790

Phoenixville

Cancer Center at Phoenixville Hospital

Carl W. Sharer
Ph: 610-983-1908

State College

Mount Nittany Medical Center

Jerome Derdel
Ph: 814-231-7813
Email: smoyer@mountnittany.org

Tennessee
Nashville

MBCCOP - Meharry Medical College - Nashville

Philip E Lammers
Ph: 615-327-5724
Email: jmurray@mmc.edu

Texas
Houston

Ben Taub General Hospital

Guilherme Godoy
Ph: 713-798-1354
Email: burton@bcm.edu

Dan L. Duncan Cancer Center at Baylor College of Medicine

Guilherme Godoy
Ph: 713-798-1354
Email: burton@bcm.edu

Veterans Affairs Medical Center - Houston

Guilherme Godoy
Ph: 713-798-1354
Email: burton@bcm.edu

San Antonio

Cancer Therapy and Research Center

Joseph W Basler
Ph: 210-450-3800
Email: CTO@uthscsa.edu

University Hospital - San Antonio

Joseph W Basler
Ph: 210-450-3800
Email: CTO@uthscsa.edu

University of Texas Health Science Center at San Antonio

Joseph W Basler
Ph: 210-450-3800
Email: CTO@uthscsa.edu

Veterans Affairs Medical Center - San Antonio (Murphy)

Joseph W Basler
Ph: 210-450-3800
Email: CTO@uthscsa.edu

Utah
American Fork

American Fork Hospital

Jay T Bishoff
Ph: 801-507-3950

Cedar City

Sandra L. Maxwell Cancer Center

Jay T Bishoff
Ph: 801-507-3950

Logan

Logan Regional Hospital

Jay T Bishoff
Ph: 801-507-3950

Murray

Jon and Karen Huntsman Cancer Center at Intermountain Medical Center

Jay T Bishoff
Ph: 801-507-3950

Ogden

Val and Ann Browning Cancer Center at McKay-Dee Hospital Center

Jay T Bishoff
Ph: 801-507-3950

Provo

Utah Valley Regional Medical Center - Provo

Jay T Bishoff
Ph: 801-507-3950

Saint George

Dixie Regional Medical Center - East Campus

Jay T Bishoff
Ph: 801-507-3950

Salt Lake City

Huntsman Cancer Institute at University of Utah

Christopher B Dechet
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

LDS Hospital

Jay T Bishoff
Ph: 801-507-3950

Utah Cancer Specialists at UCS Cancer Center

Jay T Bishoff
Ph: 801-507-3950

Washington
Auburn

Auburn Regional Center for Cancer Care

John A Keech
Ph: 907-458-5380

Bellevue

Overlake Cancer Center at Overlake Hospital Medical Center

John A Keech
Ph: 907-458-5380

Centralia

Providence Centralia Hospital

John A Keech
Ph: 907-458-5380

Everett

Providence Regional Cancer Partnership

John A Keech
Ph: 907-458-5380

Federal Way

St. Francis Hospital

John A Keech
Ph: 907-458-5380

Lacey

Western Washington Oncology, Incorporated, PS at Western Washington Cancer Center

John A Keech
Ph: 907-458-5380

Lakewood

St. Clare Hospital

John A Keech
Ph: 907-458-5380

Puyallup

Good Samaritan Cancer Center

John A Keech
Ph: 907-458-5380

Seattle

Pacific Medical Center

Craig R. Nichols
Ph: 503-215-6412
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Virginia Mason Medical Center

Craig R. Nichols
Ph: 503-215-6412
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Tacoma

Madigan Army Medical Center - Tacoma

Timothy C Brand
Ph: 253-968-0129
Email: mamcdci@amedd.army.mil

MultiCare Regional Cancer Center at Tacoma General Hospital

John A Keech
Ph: 907-458-5380

Northwest Medical Specialties, PLLC - Tacoma

John A Keech
Ph: 907-458-5380

Walla Walla

St. Mary Regional Cancer Center at St. Mary Medical Center

James R Cunningham
Ph: 800-422-6237

Wisconsin
La Crosse

Gundersen Lutheran Center for Cancer and Blood

Kurt Oettel
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Mukwonago

D.N. Greenwald Center

Timothy R Wassenaar
Ph: 262-928-7878

Oconomowoc

Regional Cancer Center at Oconomowoc Memorial Hospital

Timothy R Wassenaar
Ph: 262-928-7878

Waukesha

Waukesha Memorial Hospital Regional Cancer Center

Timothy R Wassenaar
Ph: 262-928-7878

Wyoming
Cody

Big Horn Basin Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Billings Clinic-Cody

Benjamin Thomas Marchello
Ph: 800-648-6274

Sheridan

Welch Cancer Center at Sheridan Memorial Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01238172
ClinicalTrials.gov processed this data on November 12, 2014

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.