Breast-Conserving Surgery and Radiation Therapy in Treating Patients with Multiple Ipsilateral Breast Cancer

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Basic Trial Information

PhaseTypeAgeTrial IDs
No phase specifiedBiomarker/Laboratory analysis, Prevention40 and overZ11102
NCI-2012-00707, ACOSOG-Z11102, CDR0000728605, NCT01556243

Trial Description

Summary

This phase II trial studies how well breast-conserving surgery and radiation therapy work in treating patients with breast cancer with two or more tumors in the same breast (multiple ipsilateral). Breast-conserving surgery is a less invasive type of surgery for breast cancer and may have fewer side effects and improve recovery. Radiation therapy uses high-energy x rays to kill tumor cells. Giving radiation therapy after surgery may kill any tumor cells that remain after surgery.

Further Study Information

PRIMARY OBJECTIVES:

I. To assess the local recurrence (LR) rate with breast conservation in patients with multiple ipsilateral primary breast cancer (MIBC).

SECONDARY OBJECTIVES:

I. To examine the conversion rate to mastectomy secondary to persistent positive margins; poor cosmesis within the first year of attempting breast conservation surgery (BCS) or inability to satisfy the radiation dose constraints on the boost to the lumpectomy bed of each site of disease.

II. To assess whether patients who did not undergo re-excision for close margins (< 2 mm) have a higher local recurrence (LR) rate than patients for whom negative margins were achieved.

III. To assess patient’s perception of cosmesis and incidence of breast lymphedema.

IV. To assess incidence of breast lymphedema.

V. To examine the type and severity of adverse effects of breast conserving surgery and radiation for women with multiple ipsilateral primary breast cancer (MIBC).

VI. To examine the radiation-related side effects of whole-breast radiation with a boost to 1 large or > 1 lumpectomy site.

TERTIARY OBJECTIVES:

I. To evaluate protein and gene expression patterns in tissue taken from each breast lesion and to evaluate the concordance of the findings between these lesions.

II. To compare the extent of disease described on imaging (mammography, bilateral breast magnetic resonance imaging [MRI] and other adjunctive imaging modalities) with surgical findings.

OUTLINE:

Patients undergo breast-conserving surgery (BCS) with all lesions resected to negative margins using 1 lumpectomy or 2-3 separate lumpectomy incisions at the discretion of the surgeon. Within 12 weeks following surgery, patients receive adjuvant chemotherapy and/or endocrine therapy at the discretion of the treating medical oncologist based on tumor characteristics.

Within 6-10 weeks after surgery or 8 weeks after completion of cytotoxic chemotherapy, patients undergo adjuvant whole-breast irradiation (WBI) 5 days a week for approximately 6 weeks.

After completion of study treatment, patients are followed up every 6 months 5 years.

Eligibility Criteria

Inclusion Criteria:

Ability to complete questionnaire(s) by themselves or with assistance

Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0, 1, or 2

cN0 or cN1 disease

Bilateral mammogram =< 90 days prior to date of surgery; Note: for patients undergoing more than 1 breast operation, this is the date of the first breast surgery for breast cancer treatment

Patients may be registered AFTER surgery and PRIOR TO radiation therapy if either of the criteria is met:

An area of atypia > 2 cm from the index lesion excised at the time of cancer operation is upgraded to DCIS or invasive carcinoma thereby identifying MIBC OR

Patient underwent resection of two or three foci of malignancy by breast conservation surgery with a minimum of one invasive focus of breast cancer and a minimum of 2 cm of normal breast tissue between the lesions on final pathology

Upon clinical exam and pre-operative imaging by mammogram +/- MRI, two or three foci of biopsy proven breast cancer separated by >= 2 cm of normal breast tissue; foci must include at least one focus of invasive breast carcinoma with another focus of either invasive breast carcinoma or ductal carcinoma in situ (DCIS); no more than 2 quadrants with biopsy proven breast cancer; Note: the shortest distance between lesions must be reported on mammogram +/- MRI and eligibility criteria must be met on both, if both are obtained; Note: patient is eligible for study if lesion is not visualized on all imaging modalities (i.e., any of the lesion (s) is/are visualized on MRI but not on mammogram OR visualized on mammogram but not on MRI); ultrasound cannot be used to determine patient eligibility; eligibility to be determined by bilateral mammogram +/- MRI only; fine needle aspirate of the second or third lesion to document malignancy is allowed if the first focus is shown to be invasive by core needle biopsy; patient may remain on study if, upon pathological assessment, two or three lesions identified on pre-operative imaging represent one contiguous lesion

Ability to provide written informed consent

Men are excluded from this study

Life expectancy of at least 5 years, excluding diagnosis of breast cancer (comorbid conditions should be taken into consideration, but breast cancer diagnosis is not a consideration)

Willing to return to enrolling institution for follow-up during the Active Monitoring Phase (the active treatment and observation portions) of the study; patients are encouraged to return to the enrolling institution; however, patients may receive radiation therapy at a different institution other than the enrolling institution

Exclusion Criteria:

Surgical axillary staging procedure prior to first definitive breast operation; Note: fine-needle aspiration (FNA) or core needle biopsy of axillary node is permitted

Planned partial breast radiation

Prior or current LCIS, DCIS or invasive breast cancer in the opposite breast (i.e., bilateral disease is not allowed)

Uncontrolled intercurrent illness including, but not limited to, ongoing or active infection, symptomatic congestive heart failure, unstable angina pectoris, cardiac arrhythmia, or psychiatric illness/social situations that would limit compliance with study requirements

Treatment including radiation therapy, chemotherapy, biotherapy, or hormonal therapy for this cancer prior to surgery (i.e., any neoadjuvant chemotherapy or endocrine therapy is not allowed); patients who undergo surgical resection with breast conservation and then are treated with adjuvant systemic therapy are eligible to enroll prior to the start of radiotherapy

Patients with known breast cancer (BRCA) mutations; patients who are not tested or whose testing result is not returned at the time of registration are not excluded from registering to this study

Other active malignancy =< 5 years prior to registration; EXCEPTIONS: non-melanotic skin cancer or carcinoma-in-situ of the cervix; Note: if there is a history of prior malignancy, they must not be receiving other specific treatment for their cancer

Co-morbid systemic illnesses or other severe concurrent disease which, in the judgment of the investigator, would interfere significantly with whole-breast irradiation (such as connective tissue disorders, lupus, or scleroderma)

Breast implants at time of diagnosis; Note: patients who have had implants previously removed prior to diagnosis are eligible

cNX, cN2, or cN3 disease

Prior history of ipsilateral breast cancer (DCIS, LCIS [lobular cancer in situ] or invasive)

Clinical or radiographic evidence of metastatic disease

Largest single focus of disease > 5 centimeters by either mammogram or MRI or both; Note: measurement of the largest single focus should include any satellite lesions within 1 centimeter of the index lesion

Any of the following:

Pregnant women

Nursing women

Women of childbearing potential who are unwilling to employ adequate contraception (as determined by the treating physician)

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

Alliance for Clinical Trials in Oncology

  • National Cancer Institute
Judy C. Szemere Boughey, Principal Investigator

Trial Sites

U.S.A.

California
Dublin

Epic Care-Dublin

Jon M. Greif
Ph: 510-835-9900

Jon M. Greif
Principal Investigator

Emeryville

Bay Area Breast Surgeons Inc

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Epic Care Partners in Cancer Care

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

La Jolla

UC San Diego Moores Cancer Center

Sarah L. Blair
Ph: 858-822-5354
Email: cancercto@ucsd.edu

Sarah L. Blair
Principal Investigator

Los Angeles

Cedars-Sinai Medical Center

Armando Elario Giuliano
Ph: 310-423-8965

Armando Elario Giuliano
Principal Investigator

Martinez

Contra Costa Regional Medical Center

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Oakland

Alta Bates Summit Medical Center - Summit Campus

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Bay Area Tumor Institute

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Hematology and Oncology Associates-Oakland

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

Pleasanton

Valley Medical Oncology Consultants

James Henry Feusner
Ph: 510-450-7600

James Henry Feusner
Principal Investigator

San Diego

Naval Medical Center -San Diego

Tawakalitu Omosalewa Oseni
Ph: 619-532-8712

Tawakalitu Omosalewa Oseni
Principal Investigator

Colorado
Aurora

University of Colorado Cancer Center - Anschutz Cancer Pavilion

Nicole Kounalakis
Ph: 720-848-0650

Nicole Kounalakis
Principal Investigator

Connecticut
Hartford

Saint Francis Hospital and Medical Center

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Delaware
Lewes

Beebe Medical Center

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Newark

Christiana Care Health System-Christiana Hospital

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Christiana Gynecologic Oncology LLC

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Delaware Clinical and Laboratory Physicians PA

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Helen F Graham Cancer Center

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Medical Oncology Hematology Consultants PA

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Regional Hematology and Oncology PA

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Rehoboth Beach

Beebe Health Campus

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Seaford

Nanticoke Memorial Hospital

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Wilmington

Christiana Care Health System-Wilmington Hospital

Diana Dickson-Witmer
Ph: 302-733-6227

Diana Dickson-Witmer
Principal Investigator

Florida
Clearwater

Morton Plant Hospital

Peter William Blumencranz
Ph: 727-461-8519

Peter William Blumencranz
Principal Investigator

Miami

University of Miami Miller School of Medicine-Sylvester Cancer Center

Eli Avisar
Ph: 866-574-5124
Email: Sylvester@emergingmed.com

Eli Avisar
Principal Investigator

Georgia
Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Howard A. Zaren
Ph: 800-622-6877

Howard A. Zaren
Principal Investigator

Hawaii
Aiea

Oncare Hawaii Inc-Pali Momi

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Pali Momi Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Ewa Beach

The Cancer Center of Hawaii-Leeward

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Honolulu

Kapiolani Medical Center for Women and Children

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Kuakini Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Oncare Hawaii Inc-Kuakini

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Oncare Hawaii Inc-POB II

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

OnCare Hawaii-Liliha

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Queen's Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Straub Clinic and Hospital

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

The Cancer Center of Hawaii-Liliha

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

University of Hawaii Cancer Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Lihue

Wilcox Memorial Hospital and Kauai Medical Clinic

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Idaho
Boise

Saint Alphonsus Cancer Care Center-Boise

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Coeur D'Alene

Kootenai Medical Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Post Falls

Kootenai Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Sandpoint

Kootenai Cancer

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Illinois
Bloomington

Illinois CancerCare-Bloomington

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Saint Joseph Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Canton

Illinois CancerCare-Canton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carbondale

Memorial Hospital of Carbondale

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Carthage

Illinois CancerCare-Carthage

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Centralia

Centralia Oncology Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Chicago

University of Illinois

Alejandra M. Perez-Tamayo
Ph: 312-567-2600

Alejandra M. Perez-Tamayo
Principal Investigator

Decatur

Cancer Care Center of Decatur

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Decatur Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Effingham

Crossroads Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Eureka

Illinois CancerCare-Eureka

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Galesburg

Illinois CancerCare Galesburg

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Western Illinois Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Harvey

Ingalls Memorial Hospital

Mark Farrell Kozloff
Ph: 708-915-4673
Email: clinicaltrials@ingalls.org

Mark Farrell Kozloff
Principal Investigator

Kewanee

Illinois CancerCare-Kewanee Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Macomb

Illinois CancerCare-Macomb

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Ottawa

Illinois CancerCare-Ottawa Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Radiation Oncology of Northern Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin

Illinois CancerCare-Pekin

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Pekin Cancer Treatment Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Methodist Medical Center of Illinois

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Peru

Illinois CancerCare-Peru

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Valley Radiation Oncology

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Princeton

Illinois CancerCare-Princeton

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield

Central Illinois Hematology Oncology Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Memorial Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southern Illinois University School of Medicine

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Springfield Clinic

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Swansea

Cancer Care Specialists of Illinois-Swansea

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Indiana
Avon

IU Health West Hospital

Linda K. Han
Ph: 317-274-2552

Linda K. Han
Principal Investigator

Carmel

IU Health North Hospital

Linda K. Han
Ph: 317-274-2552

Linda K. Han
Principal Investigator

Elkhart

Michiana Hematology Oncology PC-Elkhart

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

Fishers

IU Health Central Indiana Cancer Centers-Fishers

Linda K. Han
Ph: 317-274-2552

Linda K. Han
Principal Investigator

Indianapolis

Indiana University/Melvin and Bren Simon Cancer Center

Linda K. Han
Ph: 317-274-2552

Linda K. Han
Principal Investigator

IU Health Methodist Hospital

Linda K. Han
Ph: 317-274-2552

Linda K. Han
Principal Investigator

Sidney and Lois Eskenazi Hospital

Linda K. Han
Ph: 317-274-2552

Linda K. Han
Principal Investigator

Mishawaka

Memorial Regional Cancer Center Day Road

Thomas Joseph Reid
Ph: 800-284-7370

Thomas Joseph Reid
Principal Investigator

Michiana Hematology Oncology PC-Mishawaka

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

Saint Joseph Regional Medical Center-Mishawaka

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

Plymouth

Michiana Hematology Oncology PC-Plymouth

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

South Bend

Memorial Hospital of South Bend

Thomas Joseph Reid
Ph: 800-284-7370

Thomas Joseph Reid
Principal Investigator

Michiana Hematology Oncology PC-South Bend

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

Northern Indiana Cancer Research Consortium CCOP

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

Westville

Michiana Hematology Oncology PC-Westville

Robin T. Zon
Ph: 574-234-5123

Robin T. Zon
Principal Investigator

Iowa
Ames

Mary Greeley Medical Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

McFarland Clinic PC-William R Bliss Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Boone

McFarland Clinic PC-Boone

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Clive

Medical Oncology and Hematology Associates-West Des Moines

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Mercy Cancer Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Des Moines

Iowa Lutheran Hospital

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Iowa Methodist Medical Center

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Iowa Oncology Research Association CCOP

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Medical Oncology and Hematology Associates-Des Moines

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Medical Oncology and Hematology Associates-Laurel

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Mercy Medical Center - Des Moines

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Fort Dodge

McFarland Clinic PC-Trinity Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Jefferson

McFarland Clinic PC-Jefferson

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Marshalltown

McFarland Clinic PC-Marshalltown

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

West Des Moines

Mercy Medical Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Methodist West Hospital

Robert J. Behrens
Ph: 515-282-2921

Robert J. Behrens
Principal Investigator

Kansas
Overland Park

Menorah Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Luke's South Hospital

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Kentucky
Edgewood

Saint Elizabeth Medical Center South

Joseph Michael Guenther
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Joseph Michael Guenther
Principal Investigator

Fort Thomas

Saint Elizabeth Fort Thomas

Joseph Michael Guenther
Ph: 859-301-5473
Email: darla.hehman@stelizabeth.com

Joseph Michael Guenther
Principal Investigator

Lexington

Saint Joseph Hospital East

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Saint Joseph Radiation Oncology Resource Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Louisville

Jewish Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Jewish Hospital Medical Center Northeast

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

The James Graham Brown Cancer Center at University of Louisville

Nicolas Ajkay
Ph: 866-530-5516

Nicolas Ajkay
Principal Investigator

Maine
Bangor

Eastern Maine Medical Center

Thomas H. Openshaw
Ph: 207-973-4274

Thomas H. Openshaw
Principal Investigator

Maryland
Baltimore

MedStar Franklin Square Medical Center/Weinberg Cancer Institute

Bridget A. Oppong
Ph: 202-444-0381

Bridget A. Oppong
Principal Investigator

Saint Agnes Hospital

Richard S. Hudes
Ph: 410-368-2910

Richard S. Hudes
Principal Investigator

Sinai Hospital of Baltimore

Mayer Gorbaty
Ph: 410-601-6120
Email: pridgely@lifebridgehealth.org

Mayer Gorbaty
Principal Investigator

Rockville

Cancer Trials Support Unit

Judy C. Szemere Boughey

Judy C. Szemere Boughey
Principal Investigator

Massachusetts
Boston

Dana-Farber Cancer Institute

Katherina Zabicki Calvillo
Ph: 888-823-5923
Email: ctsucontact@westat.com

Katherina Zabicki Calvillo
Principal Investigator

South Weymouth

Dana-Farber/Brigham and Women's Cancer Center at South Shore

Katherina Zabicki Calvillo
Ph: 888-823-5923
Email: ctsucontact@westat.com

Katherina Zabicki Calvillo
Principal Investigator

Michigan
Ann Arbor

Saint Joseph Mercy Hospital

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Battle Creek

Bronson Battle Creek

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Dearborn

Oakwood Hospital and Medical Center

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Detroit

Saint John Hospital and Medical Center

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Wayne State University/Karmanos Cancer Institute

Mary Ann Kosir
Ph: 313-576-9363

Mary Ann Kosir
Principal Investigator

Flint

Genesys Hurley Cancer Institute

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Hurley Medical Center

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Grand Rapids

Mercy Health Saint Mary's

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Spectrum Health at Butterworth Campus

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Jackson

Allegiance Health

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Kalamazoo

Borgess Medical Center

Sunil Nagpal
Ph: 269-373-7458

Sunil Nagpal
Principal Investigator

Bronson Methodist Hospital

Raymond Sterling Lord
Ph: 269-373-7458

Raymond Sterling Lord
Principal Investigator

West Michigan Cancer Center

Raymond Sterling Lord
Ph: 269-373-7458

Raymond Sterling Lord
Principal Investigator

Lansing

Sparrow Hospital

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Livonia

Saint Mary Mercy Hospital

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Muskegon

Mercy Health Mercy Campus

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Pontiac

Saint Joseph Mercy Oakland

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Port Huron

Saint Joseph Mercy Port Huron

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Royal Oak

William Beaumont Hospital-Royal Oak

Nayana S. Dekhne
Ph: 248-551-7695

Nayana S. Dekhne
Principal Investigator

Saginaw

Saint Mary's of Michigan

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Traverse City

Munson Medical Center

Gilbert D.A. Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Gilbert D.A. Padula
Principal Investigator

Troy

William Beaumont Hospital - Troy

Nayana S. Dekhne
Ph: 248-551-7695

Nayana S. Dekhne
Principal Investigator

Warren

Saint John Macomb-Oakland Hospital

Tari Suzanne Stull
Ph: 989-667-6257

Tari Suzanne Stull
Principal Investigator

Minnesota
Burnsville

Fairview Ridges Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Coon Rapids

Mercy Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Edina

Fairview-Southdale Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Fridley

Unity Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Hutchinson

Hutchinson Area Health Care

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Maplewood

Minnesota Oncology Hematology PA-Maplewood

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Saint John's Hospital - Healtheast

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Minneapolis

Abbott-Northwestern Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Health Partners Inc

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Hennepin County Medical Center

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Robbinsdale

North Memorial Medical Health Center

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Saint Cloud

Coborn Cancer Center at Saint Cloud Hospital

Donald James Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Donald James Jurgens
Principal Investigator

Saint Cloud Hospital

Donald James Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Donald James Jurgens
Principal Investigator

Saint Louis Park

Park Nicollet Clinic - Saint Louis Park

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Saint Paul

Regions Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

United Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Shakopee

Saint Francis Regional Medical Center

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Waconia

Ridgeview Medical Center

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Willmar

Rice Memorial Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Woodbury

Minnesota Oncology and Hematology PA-Woodbury

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Missouri
Bonne Terre

Parkland Health Center-Bonne Terre

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southeast Cancer Center

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Jefferson City

Capital Region Medical Center-Goldschmidt Cancer Center

Alan P. Lyss
Ph: 800-392-0936

Alan P. Lyss
Principal Investigator

Kansas City

Heartland Hematology and Oncology Associates Incorporated

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Research Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Luke's Hospital of Kansas City

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Lee's Summit

Saint Luke's East - Lee's Summit

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Liberty

Liberty Radiation Oncology Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Joseph

Heartland Regional Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Louis

Missouri Baptist Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Washington University School of Medicine

Julie A. Margenthaler
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Julie A. Margenthaler
Principal Investigator

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Sullivan

Missouri Baptist Sullivan Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Montana
Billings

Billings Clinic Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Montana Cancer Consortium CCOP

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Saint Vincent Healthcare

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Bozeman

Bozeman Deaconess Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Butte

Saint James Community Hospital and Cancer Treatment Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Great Falls

Benefis Healthcare- Sletten Cancer Institute

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Helena

Saint Peter's Community Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Kalispell

Kalispell Regional Medical Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Missoula

Community Medical Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Saint Patrick Hospital - Community Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Nebraska
Grand Island

CHI Health Saint Francis

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Kearney

CHI Health Good Samaritan

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Omaha

Alegent Health Bergan Mercy Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Alegent Health Immanuel Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Alegent Health Lakeside Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Creighton University Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Papillion

Midlands Community Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Nevada
Henderson

21st Century Oncology - Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada-Southeast Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Las Vegas Cancer Center-Henderson

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Las Vegas

21st Century Oncology

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

21st Century Oncology - Fort Apache

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

21st Century Oncology - Vegas Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Fort Apache

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Shadow

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer and Blood Specialists-Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Cancer Therapy and Integrative Medicine

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Northwest

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada-Summerlin

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Las Vegas Cancer Center-Medical Center

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Nevada Cancer Research Foundation CCOP

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Radiation Oncology Centers of Nevada Central

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Radiation Oncology Centers of Nevada Southeast

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

University Medical Center of Southern Nevada

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

New Hampshire
Lebanon

Dartmouth Hitchcock Medical Center

Kari Michelle Rosenkranz
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Kari Michelle Rosenkranz
Principal Investigator

New Jersey
Basking Ridge

Memorial Sloan Kettering Cancer Center at Basking Ridge

Kimberly Joan Van Zee
Ph: 212-639-7202

Kimberly Joan Van Zee
Principal Investigator

New Brunswick

Saint Peter's University Hospital

Susan A. McManus
Ph: 732-745-8600ext6163
Email: kcovert@saintpetersuh.com

Susan A. McManus
Principal Investigator

New Mexico
Albuquerque

Lovelace Women's Hospital

Calvin Allen Ridgeway
Ph: 505-272-6972

Calvin Allen Ridgeway
Principal Investigator

University of New Mexico

Calvin Allen Ridgeway
Ph: 505-272-6972

Calvin Allen Ridgeway
Principal Investigator

New York
Commack

Memorial Sloan Kettering Cancer Center Commack

Kimberly Joan Van Zee
Ph: 212-639-7202

Kimberly Joan Van Zee
Principal Investigator

Manhasset

North Shore University Hospital

Dominic A. Filardi
Ph: 516-562-3467

Dominic A. Filardi
Principal Investigator

New Hyde Park

North Shore-LIJ Health System/Center for Advanced Medicine

Dominic A. Filardi
Ph: 516-562-3467

Dominic A. Filardi
Principal Investigator

New York

Memorial Sloan-Kettering Cancer Center

Kimberly Joan Van Zee
Ph: 212-639-7202

Kimberly Joan Van Zee
Principal Investigator

Poughkeepsie

Vassar Brothers Medical Center

Gregory John Zanieski
Ph: 845-483-6483

Gregory John Zanieski
Principal Investigator

Rochester

University of Rochester

Kristin Anne Skinner
Ph: 585-275-5830

Kristin Anne Skinner
Principal Investigator

Rockville Centre

Memorial Sloan-Kettering Cancer Center Rockville Centre

Kimberly Joan Van Zee
Ph: 212-639-7202

Kimberly Joan Van Zee
Principal Investigator

Sleepy Hollow

Memorial Sloan-Kettering Cancer Center Sleepy Hollow

Kimberly Joan Van Zee
Ph: 212-639-7202

Kimberly Joan Van Zee
Principal Investigator

West Harrison

Memorial Sloan-Kettering Cancer Center West Harrison

Kimberly Joan Van Zee
Ph: 212-639-7202

Kimberly Joan Van Zee
Principal Investigator

North Carolina
Asheboro

Randolph Hospital

Faera Ledford Byerly
Ph: 336-832-0821

Faera Ledford Byerly
Principal Investigator

Belmont

Gaston Hematology and Oncology Associates-Belmont

Paula Ann Lundgren
Ph: 704-834-2932

Paula Ann Lundgren
Principal Investigator

Charlotte

Carolinas Medical Center/Levine Cancer Institute

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Carolinas Medical Center/Levine Cancer Institute-Pineville

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Carolinas Medical Center/Levine Cancer Institute-University

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

CMC-LCI Radiation Therapy-Pineville

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Levine Cancer Institute-Ballantyne

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Levine Cancer Institute-Tryon

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Novant Health Presbyterian Medical Center

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

University Radiation Therapy Center

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Gastonia

CaroMont Breast Surgical Specialists-Gastonia

Paula Ann Lundgren
Ph: 704-834-2932

Paula Ann Lundgren
Principal Investigator

Gaston Hematology and Oncology Associates

Paula Ann Lundgren
Ph: 704-834-2932

Paula Ann Lundgren
Principal Investigator

Gaston Memorial Hospital

Paula Ann Lundgren
Ph: 704-834-2932

Paula Ann Lundgren
Principal Investigator

Greensboro

Cone Health Cancer Center

Faera Ledford Byerly
Ph: 336-832-0821

Faera Ledford Byerly
Principal Investigator

Monroe

Carolinas HealthCare System Union

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

Reidsville

Annie Penn Memorial Hospital

Faera Ledford Byerly
Ph: 336-832-0821

Faera Ledford Byerly
Principal Investigator

Ohio
Belpre

Strecker Cancer Center-Belpre

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Chillicothe

Adena Regional Medical Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Cincinnati

Bethesda North Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Good Samaritan Hospital - Cincinnati

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

The Christ Hospital

Jennifer B. Manders
Ph: 513-585-2859

Jennifer B. Manders
Principal Investigator

Columbus

Columbus Oncology and Hematology Associates Inc

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Doctors Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Grant Medical Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Mount Carmel Health Center West

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Riverside Methodist Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

The Mark H Zangmeister Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Delaware

Delaware Health Center-Grady Cancer Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Delaware Radiation Oncology

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Grady Memorial Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Lancaster

Fairfield Medical Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Marietta

Marietta Memorial Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Marion

OneHealth Marion General Hospital

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Mount Vernon

Knox Community Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Newark

Licking Memorial Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Newark Radiation Oncology

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Portsmouth

Southern Ohio Medical Center

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Springfield

Springfield Regional Medical Center

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Westerville

Saint Ann's Hospital

John Philip Kuebler
Ph: 614-566-3275

John Philip Kuebler
Principal Investigator

Zanesville

Genesis HealthCare System

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Oklahoma
Oklahoma City

Mercy Hospital Oklahoma City

Alan Berch Hollingsworth
Ph: 405-751-4343

Alan Berch Hollingsworth
Principal Investigator

University of Oklahoma Health Sciences Center

William Chesnut Dooley
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

William Chesnut Dooley
Principal Investigator

Oregon
Portland

Oregon Health and Science University

Charlotte Dai Kubicky
Ph: 503-494-1080
Email: trials@ohsu.edu

Charlotte Dai Kubicky
Principal Investigator

Pennsylvania
Allentown

Lehigh Valley Hospital-Cedar Crest

Suresh G. Nair
Ph: 610-402-2273

Suresh G. Nair
Principal Investigator

Bethlehem

Lehigh Valley Hospital - Muhlenberg

Suresh G. Nair
Ph: 610-402-2273

Suresh G. Nair
Principal Investigator

Bryn Mawr

Bryn Mawr Hospital

Albert S. DeNittis
Ph: 866-225-5654

Albert S. DeNittis
Principal Investigator

Lancaster

Lancaster General Hospital

Daleela Getsiv Dodge
Ph: 717-544-0511

Daleela Getsiv Dodge
Principal Investigator

Pittsburgh

University of Pittsburgh Cancer Institute (UPCI)

Gretchen McGuire Ahrendt
Ph: 412-647-2811

Gretchen McGuire Ahrendt
Principal Investigator

Wynnewood

Lankenau Medical Center

Albert S. DeNittis
Ph: 866-225-5654

Albert S. DeNittis
Principal Investigator

Rhode Island
Providence

Roger Williams Medical Center

R. James Koness
Ph: 401-456-2268
Email: rdavies@rwmc.org

R. James Koness
Principal Investigator

South Carolina
Hilton Head Island

Hilton Head Regional Medical Center

Rochelle L. Ringer
Ph: 843-792-9321

Rochelle L. Ringer
Principal Investigator

Rock Hill

Levine Cancer Institute-Rock Hill

Richard L. White
Ph: 704-355-2884

Richard L. White
Principal Investigator

South Dakota
Sioux Falls

Avera Cancer Institute

Wade Edward Dosch
Ph: 800-657-4377
Email: Jan.Healy@avera.org

Wade Edward Dosch
Principal Investigator

Tennessee
Chattanooga

Memorial Hospital

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Texas
Amarillo

Texas Tech University Health Science Center-Amarillo

Rakhshanda Layeequr Rahman
Ph: 806-354-5411

Rakhshanda Layeequr Rahman
Principal Investigator

Dallas

Parkland Memorial Hospital

Ann Marilyn Leitch
Ph: 214-648-7097

Ann Marilyn Leitch
Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

Ann Marilyn Leitch
Ph: 214-648-7097

Ann Marilyn Leitch
Principal Investigator

Houston

M D Anderson Cancer Center

Elizabeth A. Mittendorf
Ph: 713-792-3245

Elizabeth A. Mittendorf
Principal Investigator

The Methodist Hospital System

Barbara Lee Bass
Ph: 713-790-2700

Barbara Lee Bass
Principal Investigator

Laredo

Doctor's Hospital of Laredo

Gary Walter Unzeitig
Email: calgbco@calgb.org

Gary Walter Unzeitig
Principal Investigator

Utah
Salt Lake City

Huntsman Cancer Institute/University of Utah

Matthew M. Poppe
Ph: 801-581-4477
Email: clinical.trials@hci.utah.edu

Matthew M. Poppe
Principal Investigator

Vermont
Berlin

Central Vermont Medical Center/National Life Cancer Treatment

Michelle Sowden
Ph: 802-656-4101

Michelle Sowden
Principal Investigator

Burlington

University of Vermont College of Medicine

Michelle Sowden
Ph: 802-656-4101

Michelle Sowden
Principal Investigator

Saint Johnsbury

Norris Cotton Cancer Center-North

Anna Kristine Fariss
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Anna Kristine Fariss
Principal Investigator

Virginia
Charlottesville

Martha Jefferson Hospital

Lynn Thacher Dengel
Ph: 434-654-8400

Lynn Thacher Dengel
Principal Investigator

Washington
Bremerton

Harrison HealthPartners Hematology and Oncology-Bremerton

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Harrison Medical Center

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Burien

Highline Medical Center-Main Campus

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Seattle

Virginia Mason CCOP

Janie Grumley
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Janie Grumley
Principal Investigator

Virginia Mason Medical Center

Janie Grumley
Ph: 206-342-6954
Email: vmmc.cancer_clinical_research@VirginiaMason.org

Janie Grumley
Principal Investigator

Tacoma

Northwest Medical Specialties PLLC

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Wisconsin
Green Bay

Aurora BayCare Medical Center

William Lewis Owens
Ph: 800-252-2990

William Lewis Owens
Principal Investigator

Green Bay Oncology at Saint Vincent Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Green Bay Oncology Limited at Saint Mary's Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Saint Mary's Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Saint Vincent Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

La Crosse

Gundersen Lutheran Medical Center

Jeanne M. Johnson
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Jeanne M. Johnson
Principal Investigator

Milwaukee

Aurora Saint Luke's Medical Center

Judy Angela Tjoe
Ph: 800-252-2990

Judy Angela Tjoe
Principal Investigator

Aurora Sinai Medical Center

Judy Angela Tjoe
Ph: 800-252-2990

Judy Angela Tjoe
Principal Investigator

Froedtert and the Medical College of Wisconsin

Tina W. F. Yen
Ph: 414-805-4380

Tina W. F. Yen
Principal Investigator

New Richmond

Cancer Center of Western Wisconsin

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

William Lewis Owens
Ph: 800-252-2990

William Lewis Owens
Principal Investigator

Summit

Aurora Medical Center in Summit

William Lewis Owens
Ph: 800-252-2990

William Lewis Owens
Principal Investigator

West Allis

Aurora West Allis Medical Center

Judy Angela Tjoe
Ph: 800-252-2990

Judy Angela Tjoe
Principal Investigator

Wyoming
Cody

Big Horn Basin Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Billings Clinic-Cody

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Sheridan

Welch Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifer NCT01556243

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.