A Study to Evaluate Genetic Predictors of Aromatase Inhibitor Musculoskeletal Symptoms (AIMSS)

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
No phase specifiedBiomarker/Laboratory analysis, Supportive careActive18 and overNCI, OtherE1Z11
NCI-2013-00426, U10CA037403, NCT01824836

Trial Description

Summary

E1Z11 is a study to determine whether certain genetic information can predict which breast cancer patients will discontinue treatment with AIs due to the development of musculoskeletal symptoms (MSS). Women with stage 1-111 breast cancer who are prescribed the aromatase inhibitor anastrozole as treatment may join.

Further Study Information

PRIMARY OBJECTIVES:

I. To validate previously identified associations between 10 specific single nucleotide polymorphisms (single nucleotide polymorphisms [SNPs]) and discontinuation of treatment with aromatase inhibitors (AIs) due to the development of musculoskeletal symptoms (MSS) among women with breast cancer.

SECONDARY OBJECTIVES:

I. To determine whether other SNPs in cytochrome P450 enzymes (CYP), glucuronosyltransferases (UGT), Vitamin D, serotonin and other receptors are associated with discontinuation of treatment due to the development of severe aromatase inhibitor-associated musculoskeletal symptoms (AIMSS).

II. To determine whether other SNPs in CYP, UGT, Vitamin D, serotonin and other receptors are associated with the development of other potential complications of AI therapy.

III. To develop a gene signature that can identify patients at risk for developing severe anastrozole-related AIMSS and other potential complications of AI therapy.

IV. To determine the epidemiology and predictors of severe AIMSS and of AI discontinuation.

V. To describe patient reported outcomes for minority patients with breast cancer treated with AIs.

VI. To assess the utility of the Patient Reported Outcomes Management Information System (PROMIS) system to collect patient reported outcomes in a cooperative group study, and validate the PROMIS Physical Function 20a form in patients with AIMSS.

VII. To develop a model that incorporates patient ratings of treatment burden, fear of recurrence and adherence behaviors to describe patient decisions to continue or discontinue anastrozole.

VIII. To collect serum samples for future testing for biomarkers of AIMSS.

OUTLINE:

Patients receive anastrozole orally (PO) once daily (QD) for 12 months.

After the completion of study treatment, patients are followed up for 12 months.

Eligibility Criteria

Inclusion Criteria:

  • Patients must be post-menopausal; post-menopausal will be defined as women meeting any of the following criteria:
  • >= 60 years of age; or
  • < 60 years of age and amenorrheic for >= 12 months prior to day 1 if uterus/ovaries are intact; or
  • < 60 years of age, and the last menstrual period 6-12 months prior to day 1, if intact uterus/ovaries and meets biochemical criteria for menopause (follicle-stimulating hormone [FSH] and estradiol within institutional standard for postmenopausal status); or
  • < 60 years of age, without a uterus, and meets biochemical criteria for menopause (FSH and estradiol within institutional standards for postmenopausal status); or
  • < 60 years of age and history of bilateral oophorectomy; surgery must have been completed at least 4 weeks prior to day 1; or
  • Prior radiation castration with amenorrhea for at least 6 months
  • Patients must have estrogen and/or progesterone receptor positive histologically confirmed stage I-III adenocarcinoma of the breast
  • Patients must have completed recommended local therapy and adjuvant chemotherapy for breast cancer
  • Patients must not have received prior AI therapy with exemestane, letrozole, or anastrozole as adjuvant therapy or for prevention of breast cancer; prior tamoxifen as adjuvant therapy or for prevention is allowed
  • Plan to treat with anastrozole for at least 12 months
  • Eastern Cooperative Oncology Group (ECOG) performance status between 0-2
  • Patients must not be currently taking (or have taken in the past 6 months) ongoing, daily analgesic medication for active, chronic conditions (i.e., rheumatoid arthritis, carpal tunnel syndrome, tenosynovitis, systemic lupus erythematosus, gout, fibromyalgia, or severe osteoarthritis involving the hands, wrists, hips, knees, feet or ankles); (note: patients taking daily low dose aspirin are allowed to participate in this trial)
  • Patients must not have a prior history of deep vein thrombosis (DVT) or pulmonary embolism in the past 5 years
  • Patients must have worst pain rated as less than 4 out of 10 on the following question: "In the past week, how much pain have you had on a scale of 0 to 10, where 0 equals no pain and 10 means the worst pain you can imagine; " NOTE: This question regarding patient's pain should be completed within one week prior to registration; this pain item may be completed orally prior to consent up to 7 days prior to registration; it is not necessary to complete this pain item via the PROMIS website
  • Patients must have adequate hepatic, hematologic and renal functioning to be able to be administered anastrozole at the discretion of the treating physician

Trial Contact Information

Trial Lead Organizations/Sponsors

Eastern Cooperative Oncology Group

  • National Cancer Institute
Vered Stearns, Principal Investigator

Trial Sites

U.S.A.

California
Anaheim

Kaiser Permanente Medical Center - Anaheim/Orange County

Jonathan A. Polikoff
Ph: 626-564-3455

Baldwin Park

Kaiser Permanente Medical Center - Baldwin Park

Jonathan A. Polikoff
Ph: 626-564-3455

Bellflower

Kaiser Permanente Medical Center - Bellflower

Jonathan A. Polikoff
Ph: 626-564-3455

Burbank

Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center

Kelly S Perlewitz
Ph: 503-537-1463

Dublin

Epic Care-Dublin

James H. Feusner
Ph: 510-450-7600

Emeryville

Bay Area Breast Surgeons, Incorporated

James H. Feusner
Ph: 510-450-7600

Epic Care - Oakland

James H. Feusner
Ph: 510-450-7600

Fairfield

North Bay Cancer Center

Brian G Vikstrom
Ph: 707-646-4016

Fontana

Kaiser Permanente Medical Center - Fontana

Jonathan A. Polikoff
Ph: 626-564-3455

Harbor City

Kaiser Permanente Medical Center - Harbor City

Jonathan A. Polikoff
Ph: 626-564-3455

Irvine

Kaiser Permanente - Irvine

Jonathan A. Polikoff
Ph: 626-564-3455

Los Angeles

Kaiser Foundation Hospital - West Los Angeles

Jonathan A. Polikoff
Ph: 626-564-3455

Kaiser Permanente Medical Center - Los Angeles

Jonathan A. Polikoff
Ph: 626-564-3455

Martinez

Contra Costa Regional Medical Center

James H. Feusner
Ph: 510-450-7600

Oakland

Alta Bates Summit Medical Center - Summit Campus

James H. Feusner
Ph: 510-450-7600

CCOP - Bay Area Tumor Institute

James H. Feusner
Ph: 510-450-7600

Larry G Strieff MD Medical Corporation

James H. Feusner
Ph: 510-450-7600

Panorama City

Kaiser Permanente Medical Group

Jonathan A. Polikoff
Ph: 626-564-3455

Paradise

Feather River Hospital Cancer Center

Sam Mazj
Ph: 530-876-7995
Email: haleew@ah.org

Pleasanton

Valley Medical Oncology Consultants - Pleasanton

James H. Feusner
Ph: 510-450-7600

Riverside

Kaiser Permanente Medical Center - Riverside

Jonathan A. Polikoff
Ph: 626-564-3455

San Diego

Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego

Jonathan A. Polikoff
Ph: 626-564-3455

Kaiser Permanente Medical Office -Vandever Medical Office

Jonathan A. Polikoff
Ph: 626-564-3455

Naval Medical Center - San Diego

Preston S. Gable
Ph: 619-532-8712

San Jose

Santa Clara Valley Medical Center

Sangeeta Aggarwal
Ph: 888-823-5923
Email: ctsucontact@westat.com

San Marcos

Kaiser Permanente Health Care

Jonathan A. Polikoff
Ph: 626-564-3455

Woodland Hills

Kaiser Permanente Medical Cener - Woodland Hills

Jonathan A. Polikoff
Ph: 626-564-3455

Colorado
Aurora

Medical Center of Aurora - South Campus

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Aurora

Keren Sturtz
Ph: 888-785-6789

Boulder

Boulder Community Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 888-785-6789

Colorado Springs

Penrose Cancer Center at Penrose Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers at the Pavilion

Keren Sturtz
Ph: 888-785-6789

Denver

CCOP - Colorado Cancer Research Program

Keren Sturtz
Ph: 888-785-6789

Colorado Blood Cancer Institute

Keren Sturtz
Ph: 888-785-6789

Porter Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Presbyterian - St. Luke's Medical Center

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Denver Midtown

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers-Rose

Keren Sturtz
Ph: 888-785-6789

Rose Medical Center

Keren Sturtz
Ph: 888-785-6789

St. Joseph Hospital

Keren Sturtz
Ph: 888-785-6789

Durango

Mercy Medical Center

Cynthia K. Cathcart
Ph: 888-785-6789

Southwest Oncology, PC

Keren Sturtz
Ph: 888-785-6789

Englewood

Comprehensive Cancer Care and Research Institute of Colorado LLC

Keren Sturtz
Ph: 888-785-6789

Swedish Medical Center

Keren Sturtz
Ph: 888-785-6789

Fort Collins

Poudre Valley Hospital

Regina J Brown
Ph: 970-297-6150

Golden

Mountain Blue Cancer Care Center

Keren Sturtz
Ph: 888-785-6789

Greeley

North Colorado Medical Center

Keren Sturtz
Ph: 888-785-6789

Greenwood Village

Breast Cancer Care Consultants

Keren Sturtz
Ph: 888-785-6789

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Keren Sturtz
Ph: 888-785-6789

St. Anthony Central Hospital

Keren Sturtz
Ph: 888-785-6789

Littleton

Littleton Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Littleton

Keren Sturtz
Ph: 888-785-6789

Lone Tree

Rocky Mountain Cancer Centers - Lone Tree

Keren Sturtz
Ph: 888-785-6789

Sky Ridge Medical Center

Keren Sturtz
Ph: 888-785-6789

Longmont

Hope Cancer Care Center at Longmont United Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Longmont

Keren Sturtz
Ph: 888-785-6789

Loveland

McKee Medical Center

Keren Sturtz
Ph: 888-785-6789

Parker

Parker Adventist Hospital

Keren Sturtz
Ph: 888-785-6789

Rocky Mountain Cancer Centers - Parker

Keren Sturtz
Ph: 888-785-6789

Pueblo

Rocky Mountain Cancer Centers - Pueblo

Keren Sturtz
Ph: 888-785-6789

St. Mary - Corwin Regional Medical Center

Keren Sturtz
Ph: 888-785-6789

Thornton

Rocky Mountain Cancer Centers - Thornton

Keren Sturtz
Ph: 888-785-6789

Wheat Ridge

Exempla Lutheran Medical Center

Keren Sturtz
Ph: 888-785-6789

Connecticut
Greenwich

Bendheim Cancer Center at Greenwich Hospital

Beverly J Drucker
Ph: 203-863-3698

Hartford

Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Manchester

Manchester Memorial Hospital

Michael A Reale
Ph: 860-533-4000

Middletown

Middlesex Hospital Cancer Center

Susanna Hong
Ph: 860-358-2058

Delaware
Dover

Kent General Hospital

Iftekhar A. Khan
Ph: 302-744-6755
Email: mary_ella_quillen@bayhealth.org

Lewes

Tunnell Cancer Center at Beebe Medical Center

Gregory A. Masters
Ph: 302-733-6227

Newark

Christiana Gynecologic Oncology, LLC

Gregory A. Masters
Ph: 302-733-6227

Delaware Clinical and Laboratory Physicians

Gregory A. Masters
Ph: 302-733-6227

Helen F. Graham Cancer Center at Christiana Hospital

Gregory A. Masters
Ph: 302-733-6227

Gregory A. Masters
Ph: 302-733-6227

Medical Oncology Hematology Consultants, PA at Helen F. Graham Cancer Center

Gregory A. Masters
Ph: 302-733-6227

Regional Hematology/Oncology, PA - Newark

Gregory A. Masters
Ph: 302-733-6227

Rehoboth Beach

Beebe Health Campus

Gregory A. Masters
Ph: 302-733-6227

Seaford

Nanticoke Memorial Hospital

Gregory A. Masters
Ph: 302-733-6227

Wilmington

Christiana Care Health System-Wilmington Hospital

Gregory A. Masters
Ph: 302-733-6227

District of Columbia
Washington

Sibley Memorial Hospital

Karen L Smith
Ph: 202-243-2373

Florida
Jacksonville

St. Vincent's Medical Center

Joel A. Stone
Ph: 904-538-3667

Lakeland

Lakeland Regional Cancer Center at Lakeland Regional Medical Center

Madhavi L. Venigalla
Ph: 863-904-1900

Miami Beach

CCOP - Mount Sinai Medical Center

Elisa Krill-Jackson
Ph: 305-674-2625
Email: info@msccop.com

Georgia
Columbus

John B. Amos Cancer Center

Andrew W. Pippas
Ph: 706-660-6404

Savannah

Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center

Harvey C. Lebos
Ph: 912-350-8568

Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

Mark A. Taylor
Ph: 912-350-8568

Hawaii
Aiea

Kapiolani Medical Center at Pali Momi

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Ph: 808-586-2979

Honolulu

Cancer Research Center of Hawaii

Jeffrey L. Berenberg
Ph: 808-586-2979

OnCare Hawaii, Incorporated - Kuakini

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Ph: 808-586-2979

OnCare Hawaii, Incorporated - Lusitana

Jeffrey L. Berenberg
Ph: 808-586-2979

Queen's Cancer Institute at Queen's Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Straub Clinic and Hospital, Incorporated

Jeffrey L. Berenberg
Ph: 808-586-2979

Tripler Army Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Lihue

Kauai Medical Clinic

Jeffrey L. Berenberg
Ph: 808-586-2979

Idaho
Boise

Mountain States Tumor Institute at St. Luke's Regional Medical Center

Paul G. Montgomery
Ph: 800-845-4624

Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

Philip J. Stella
Ph: 734-712-4673

Fruitland

Saint Luke's Mountain States Tumor Institute - Fruitland

Paul G. Montgomery
Ph: 800-845-4624

Meridian

Mountain States Tumor Institute - Meridian

Paul G. Montgomery
Ph: 800-845-4624

Nampa

Saint Luke's Mountain States Tumor Institute

Paul G. Montgomery
Ph: 800-845-4624

Post Falls

Kootenai Cancer Center - Post Falls

Benjamin Thomas Marchello
Ph: 800-648-6274

Twin Falls

Mountain States Tumor Institute at St. Luke's

Paul G. Montgomery
Ph: 800-845-4624

Illinois
Aurora

Rush-Copley Cancer Care Center

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Berwyn

MacNeal Cancer Center at MacNeal Hospital

Jeffrey K Zawacki
Ph: 773-564-5044

Bloomington

Illinois CancerCare - Bloomington

Nguyet A Le-Lindqwister
Ph: 800-793-2262

St. Joseph Medical Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Canton

Illinois CancerCare - Canton

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Carbondale

Memorial Hospital of Carbondale

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Carthage

Illinois CancerCare - Carthage

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Centralia

Centralia Oncology Clinic

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Chicago

Creticos Cancer Center at Advocate Illinois Masonic Medical Center

Sangeetha Nimmagadda
Ph: 773-296-5360

John H. Stroger, Jr. Hospital of Cook County

Thomas E. Lad
Ph: 312-864-6000

Louis A. Weiss Memorial Hospital

Keith L. Shulman
Ph: 773-564-5044

Mount Sinai Hospital Medical Center

Mohammed A Kassem
Ph: 773-257-5960
Email: suhi@sinai.org

Resurrection Medical Center

Christopher G. Rose
Ph: 773-792-5116

Swedish Covenant Hospital

Elyse A Lambiase
Ph: 847-316-6994

Danville

Carle on Vermilion

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Decatur

Cancer Care Center of Decatur

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Decatur Memorial Hospital Cancer Care Institute

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Effingham

Carle Physician Group-Effingham

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Crossroads Cancer Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Eureka

Illinois CancerCare - Eureka

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Evanston

St. Francis Hospital

Elyse A Lambiase
Ph: 847-316-6994

Galesburg

Galesburg Clinic, PC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Medical and Surgical Specialists, LLC

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Harvey

Ingalls Cancer Care Center at Ingalls Memorial Hospital

Mark F. Kozloff
Ph: 708-915-4673
Email: clinicaltrials@ingalls.org

Hinsdale

Hinsdale Hematology Oncology Associates

Elyse Cheryl Schneiderman
Ph: 630-654-1790
Email: info@hhoaltd.com

Kewanee

Illinois CancerCare - Kewanee Clinic

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Macomb

Illinois CancerCare - Macomb

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Mattoon

Carle Physician Group-Mattoon/Charleston

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Mount Vernon

Good Samaritan Regional Health Center

Jay W Carlson
Ph: 800-821-7532

Ottawa

Illinois CancerCare - Ottawa

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Pekin

Cancer Treatment Center at Pekin Hospital

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Illinois CancerCare - Pekin

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Peoria

Illinois CancerCare - Peoria

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Methodist Medical Center of Illinois

Nguyet A Le-Lindqwister
Ph: 800-793-2262

OSF St. Francis Medical Center

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Peru

Illinois CancerCare - Princeton

Nguyet A Le-Lindqwister
Ph: 800-793-2262

Princeton

Illinois CancerCare - Princeton

Nguyet A Le-Lindqwister
Ph: 800-793-2262

River Forest

West Suburban Center for Cancer Care

Isoken Koko
Ph: 708-488-0882

Rockford

Advanced Care and Treatment Medical Group, PC

Harvey Eric Einhorn
Ph: 779-696-9400
Email: cancercare@swedishamerican.org

Springfield

Regional Cancer Center at Memorial Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Urbana

Carle Cancer Center at Carle Foundation Hospital

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Yorkville

Rush-Copley Healthcare Center

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Indiana
Elkhart

Michiana Hematology-Oncology, PC - Elkhart

Jose A. Bufill
Ph: 574-237-1328

Indianapolis

Indiana University Melvin and Bren Simon Cancer Center

Kathy Miller
Ph: 317-274-2552

Michigan City

Saint Anthony Memorial Health Centers

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Woodland Cancer Care Center

Maria T Grosse-Perdekamp
Ph: 800-446-5532

Mishawaka

Memorial Regional Cancer Center Day Road

Thomas Joseph Reid
Ph: 800-284-7370

Michiana Hematology-Oncology, PC - Mishawaka

Jose A. Bufill
Ph: 574-237-1328

Saint Joseph's Medical Center

Jose A. Bufill
Ph: 574-237-1328

Muncie

Cancer Center at Ball Memorial Hospital

Dejuania A Brown
Ph: 765-751-5850

Plymouth

Michiana Hematology Oncology PC - Plymouth

Jose A. Bufill
Ph: 574-237-1328

Richmond

Reid Hospital & Health Care Services

Howard M. Gross
Ph: 937-775-1350

South Bend

CCOP - Northern Indiana CR Consortium

Jose A. Bufill
Ph: 574-237-1328

Memorial Hospital of South Bend

Jose A. Bufill
Ph: 574-237-1328

Michiana Hematology-Oncology, PC - South Bend

Jose A. Bufill
Ph: 574-237-1328

Westville

Michiana Hematology Oncology-PC Westville

Jose A. Bufill
Ph: 574-237-1328

Iowa
Ames

McFarland Clinic, PC

Joseph James Merchant
Ph: 515-239-2621

William R. Bliss Cancer Center at Mary Greeley Medical Center

Joseph James Merchant
Ph: 515-239-2621

Boone

McFarland Clinic PC-Boone

Joseph James Merchant
Ph: 515-239-2621

Cedar Rapids

Cedar Rapids Oncology Associates

Deborah W Wilbur
Ph: 319-363-2690

Mercy Regional Cancer Center at Mercy Medical Center

Deborah W Wilbur
Ph: 319-363-2690

Clive

Medical Oncology and Hematology Associates-West Des Moines

Robert J Behrens
Ph: 515-282-2921

Mercy Cancer Center - West Lakes

Robert J Behrens
Ph: 515-282-2921

Des Moines

CCOP - Iowa Oncology Research Association

Robert J Behrens
Ph: 515-282-2921

John Stoddard Cancer Center at Iowa Lutheran Hospital

Robert J Behrens
Ph: 515-282-2921

John Stoddard Cancer Center at Iowa Methodist Medical Center

Robert J Behrens
Ph: 515-282-2921

Medical Oncology and Hematology Associates at John Stoddard Cancer Center

Robert J Behrens
Ph: 515-282-2921

Medical Oncology and Hematology Associates at Mercy Cancer Center

Robert J Behrens
Ph: 515-282-2921

Mercy Cancer Center at Mercy Medical Center - Des Moines

Robert J Behrens
Ph: 515-282-2921

Fairfield

JCHC McCreery Cancer Center

Robert J Behrens
Ph: 515-282-2921

Fort Dodge

Trinity Regional Medical Center

Joseph James Merchant
Ph: 515-239-2621

Jefferson

McFarland Clinic PC-Jefferson

Joseph James Merchant
Ph: 515-239-2621

Marshalltown

McFarland Clinic PC-Marshalltown

Joseph James Merchant
Ph: 515-239-2621

Mason City

Mercy Cancer Center at Mercy Medical Center - North Iowa

Arvind Y Vemula
Ph: 800-433-3883

Ottumwa

South Iowa Radiation Oncology Center at Ottumwa Regional Health Center

Robert J Behrens
Ph: 515-282-2921

Sioux City

Siouxland Hematology-Oncology Associates, LLP

Donald Bruce Wender
Ph: 712-252-0088

West Des Moines

Methodist West Hospital

Robert J Behrens
Ph: 515-282-2921

Robert J Behrens
Ph: 515-282-2921

Kansas
Chanute

Cancer Center of Kansas, PA - Chanute

Shaker R. Dakhil
Ph: 316-262-4467

Dodge City

Cancer Center of Kansas, PA - Dodge City

Shaker R. Dakhil
Ph: 316-262-4467

El Dorado

Cancer Center of Kansas, PA - El Dorado

Shaker R. Dakhil
Ph: 316-262-4467

Fort Scott

Cancer Center of Kansas - Fort Scott

Shaker R. Dakhil
Ph: 316-262-4467

Independence

Cancer Center of Kansas-Independence

Shaker R. Dakhil
Ph: 316-262-4467

Kingman

Cancer Center of Kansas, PA - Kingman

Shaker R. Dakhil
Ph: 316-262-4467

Lawrence

Lawrence Memorial Hospital

Shaker R. Dakhil
Ph: 316-262-4467

Liberal

Cancer Center of Kansas, PA - Liberal

Shaker R. Dakhil
Ph: 316-262-4467

Newton

Cancer Center of Kansas, PA - Newton

Shaker R. Dakhil
Ph: 316-262-4467

Overland Park

Menorah Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Luke's Hospital - South

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Parsons

Cancer Center of Kansas, PA - Parsons

Shaker R. Dakhil
Ph: 316-262-4467

Pratt

Cancer Center of Kansas, PA - Pratt

Shaker R. Dakhil
Ph: 316-262-4467

Salina

Cancer Center of Kansas, PA - Salina

Shaker R. Dakhil
Ph: 316-262-4467

Wellington

Cancer Center of Kansas, PA - Wellington

Shaker R. Dakhil
Ph: 316-262-4467

Wichita

Associates in Women's Health, PA - North Hillside

Shaker R. Dakhil
Ph: 316-262-4467

Cancer Center of Kansas, PA - Medical Arts Tower

Shaker R. Dakhil
Ph: 316-262-4467

Cancer Center of Kansas, PA - Wichita

Shaker R. Dakhil
Ph: 316-262-4467

Via Christi Cancer Center at Via Christi Regional Medical Center

Shaker R. Dakhil
Ph: 316-262-4467

Winfield

Cancer Center of Kansas, PA - Winfield

Shaker R. Dakhil
Ph: 316-262-4467

Kentucky
Corbin

Baptist Regional Medical Center

Firas B Badin
Ph: 859-260-6425

Crestview Hills

Oncology Hematology Care, Incorporated - Crestview Hills

Howard M. Gross
Ph: 937-775-1350

Lexington

Central Baptist Hospital

Firas B Badin
Ph: 859-260-6425

University of Kentucky Chandler Medical Center

Mara D Chambers
Ph: 859-257-3379

Louisiana
Baton Rouge

Ochsner Health Center - Bluebonnet

John T Cole
Ph: 888-562-4763

Monroe

Louisiana State University Health Sciences Center - Monroe

Gary V Burton
Ph: 318-813-1412

New Orleans

Ochsner Cancer Institute at Ochsner Clinic Foundation

John T Cole
Ph: 888-562-4763

Shreveport

Feist-Weiller Cancer Center at Louisiana State University Health Sciences

Gary V Burton
Ph: 318-813-1412

Maine
York

York Hospital's Oncology Treatment Center

Jonathan D Eneman
Ph: 207-351-3777

Maryland
Baltimore

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

Vered Stearns
Ph: 410-955-8804
Email: jhcccro@jhmi.edu

Bethesda

Suburban Hospital

Carolyn Bennett Hendricks
Ph: 301-896-2719
Email: Bsquiller@suburbanhospital.org

Cumberland

Regional Cancer Center at Western Maryland Health System - Sacred Heart Campus

Blanche Mavromatis
Ph: 240-964-1400

Easton

Shore Regional Cancer Center at Memorial Hospital - Easton

Susan T Forlifer
Ph: 410-820-6800ext108
Email: srichter@shorehealth.org

Silver Spring

Holy Cross Hospital

Cheryl A. Aylesworth
Ph: 301-896-2719
Email: Bsquiller@suburbanhospital.org

Massachusetts
Attleboro

Sturdy Memorial Hospital

Colleen K Yavarow
Ph: 508-236-7059

Beverly

Beverly Hospital

Angus P. McIntyre
Ph: 978-283-4000ext559

Cambridge

Mount Auburn Hospital

Lisa B Weissmann
Ph: 888-823-5923
Email: ctsucontact@westat.com

Fall River

Hudner Oncology Center at Saint Anne's Hospital - Fall River

John L Yang
Ph: 508-674-5600

Lowell

Lowell General Hospital

Blair Ardman
Ph: 978-788-7084
Email: ghincks@lowellgeneral.org

Michigan
Adrian

Hickman Cancer Center at Bixby Medical Center

Rex B Mowat
Ph: 800-444-3561

Ann Arbor

Saint Joseph Mercy Cancer Center

Philip J. Stella
Ph: 734-712-4673

University of Michigan Comprehensive Cancer Center

Norah L Henry
Ph: 800-865-1125

Battle Creek

Battle Creek Health System Cancer Care Center

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Dearborn

Oakwood Cancer Center at Oakwood Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Detroit

Van Elslander Cancer Center at St. John Hospital and Medical Center

Philip J. Stella
Ph: 734-712-4673

Escanaba

Green Bay Oncology, Limited - Escanaba

Brian L Burnette
Ph: 800-432-6049

Flint

Genesys Hurley Cancer Institute

Philip J. Stella
Ph: 734-712-4673

Hurley Medical Center

Philip J. Stella
Ph: 734-712-4673

Grand Rapids

Butterworth Hospital at Spectrum Health

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Lacks Cancer Center at Saint Mary's Health Care

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Iron Mountain

Green Bay Oncology - Iron Mountain

Brian L Burnette
Ph: 800-432-6049

Jackson

Gayle M. Jacob Cancer Center at Allegiance Health

Philip J. Stella
Ph: 734-712-4673

Kalamazoo

Borgess Medical Center

Raymond Sterling Lord
Ph: 269-373-7458

Bronson Methodist Hospital

Raymond Sterling Lord
Ph: 269-373-7458

West Michigan Cancer Center

Raymond Sterling Lord
Ph: 269-373-7458

Lansing

Sparrow Regional Cancer Center

Philip J. Stella
Ph: 734-712-4673

Livonia

St. Mary Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Monroe

Community Cancer Center of Monroe

Rex B Mowat
Ph: 800-444-3561

Muskegon

Mercy General Health Partners

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Niles

Lakeland Hospital - Niles

Jose A. Bufill
Ph: 574-237-1328

Pontiac

St. Joseph Mercy Oakland

Philip J. Stella
Ph: 734-712-4673

Port Huron

Mercy Regional Cancer Center at Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Reed City

Spectrum Health Reed City Hospital

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Saginaw

Seton Cancer Institute at Saint Mary's - Saginaw

Philip J. Stella
Ph: 734-712-4673

Saint Joseph

Lakeside Cancer Specialists, PLLC

Jose A. Bufill
Ph: 574-237-1328

Southfield

Providence Hospital - Southfield

Andrew A Muskovitz
Ph: 248-849-5337
Email: jaswinder.grewal@stjohn.org

St. Joseph

Lakeland Regional Cancer Care Center - St. Joseph

Jose A. Bufill
Ph: 574-237-1328

Traverse City

Munson Medical Center

Gilbert D Padula
Ph: 616-685-5225
Email: connie.szczepanek@grcop.org

Warren

St. John Macomb Hospital

Philip J. Stella
Ph: 734-712-4673

Minnesota
Bemidji

MeritCare Bemidji

Preston D. Steen
Ph: 701-234-6161

Brainerd

St. Joseph's Medical Center

Bret E Friday
Ph: 888-203-7267

Burnsville

Fairview Ridges Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Coon Rapids

Mercy and Unity Cancer Center at Mercy Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Duluth

CCOP - Duluth

Bret E Friday
Ph: 888-203-7267

Essentia Health - Duluth Clinic

Bret E Friday
Ph: 888-203-7267

Miller - Dwan Medical Center

Bret E Friday
Ph: 888-203-7267

St. Luke's Hospital Cancer Care Center

Basem S Goueli
Ph: 888-823-5923
Email: ctsucontact@westat.com

Edina

Fairview Southdale Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Fergus Falls

Lake Region Healthcare Corporation-Cancer Care

Bret E Friday
Ph: 888-203-7267

Fridley

Mercy and Unity Cancer Center at Unity Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Hutchinson

Hutchinson Area Health Care

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Maplewood

HealthEast Cancer Care at St. John's Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Minnesota Oncology - Maplewood

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Minneapolis

Health Partners Inc

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Hennepin County Medical Center - Minneapolis

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Virginia Piper Cancer Institute at Abbott - Northwestern Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

New Ulm

New Ulm Medical Center

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Robbinsdale

Humphrey Cancer Center at North Memorial Outpatient Center

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Saint Cloud

CentraCare Clinic - Women and Children

Donald J Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Coborn Cancer Center

Donald J Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Saint Louis Park

Park Nicollet Cancer Center

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Saint Paul

Regions Hospital Cancer Care Center

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

United Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Shakopee

St. Francis Cancer Center at St. Francis Medical Center

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Stillwater

Lakeview Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Waconia

Ridgeview Medical Center

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Willmar

Willmar Cancer Center at Rice Memorial Hospital

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Woodbury

Minnesota Oncology - Woodbury

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Missouri
Bonne Terre

Parkland Health Center-Bonne Terre

Bryan A Faller
Ph: 800-392-0936

Branson

Skaggs Cancer Center at Skaggs Regional Medical Center

Jay W Carlson
Ph: 800-821-7532

Cape Girardeau

Saint Francis Medical Center

James L. Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

Southeast Cancer Center

Bryan A Faller
Ph: 800-392-0936

Independence

Independence Regional Health Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Jefferson City

Goldschmidt Cancer Center

Bryan A Faller
Ph: 800-392-0936

Joplin

St. John's Regional Medical Center

Jay W Carlson
Ph: 800-821-7532

Kansas City

Heartland Hematology Oncology Associates, Incorporated

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Research Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Luke's Hospital

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Lee's Summit

Saint Luke's East - Lee's Summit

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Liberty

Parvin Radiation Oncology

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Rolla

Mercy Clinic Cancer and Hematology - Rolla

Jay W Carlson
Ph: 800-821-7532

Phelps County Regional Medical Center

Jay W Carlson
Ph: 800-821-7532

Saint Joseph

Heartland Regional Medical Center

Rakesh Gaur
Ph: 913-948-5588
Email: aroland@kccop.org

Saint Louis

David C. Pratt Cancer Center at St. John's Mercy

Jay W Carlson
Ph: 800-821-7532

Mercy Clinic St. Louis Cancer and Breast Institute

Jay W Carlson
Ph: 800-821-7532

Missouri Baptist Cancer Center

Bryan A Faller
Ph: 800-392-0936

Sainte Genevieve

Sainte Genevieve County Memorial Hospital

Bryan A Faller
Ph: 800-392-0936

Springfield

Hulston Cancer Center at Cox Medical Center South

Jay W Carlson
Ph: 800-821-7532

St. John's Regional Health Center

Jay W Carlson
Ph: 800-821-7532

Sullivan

Missouri Baptist Sullivan Hospital

Bryan A Faller
Ph: 800-392-0936

Sunset Hills

Missouri Baptist Outpatient Center-Sunset Hills

Bryan A Faller
Ph: 800-392-0936

Montana
Billings

Billings Clinic Cancer Center - 801 N 29th Street

Benjamin Thomas Marchello
Ph: 800-648-6274

CCOP - Montana Cancer Consortium

Benjamin Thomas Marchello
Ph: 800-648-6274

St. Vincent Healthcare Cancer Care Services

Benjamin Thomas Marchello
Ph: 800-648-6274

Bozeman

Bozeman Deaconess Cancer Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Butte

St. James Healthcare Cancer Care

Benjamin Thomas Marchello
Ph: 800-648-6274

Great Falls

Benefis Sletten Cancer Institute

Benjamin Thomas Marchello
Ph: 800-648-6274

Helena

St. Peter's Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Kalispell

Kalispell Regional Medical Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Missoula

Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

Benjamin Thomas Marchello
Ph: 800-648-6274

Nebraska
Kearney

Good Samaritan Cancer Center at Good Samaritan Hospital

Nicholas J Hartl
Ph: 308-865-7963

Lincoln

Cancer Resource Center - Lincoln

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Nebraska Hematology and Oncology

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Southeast Nebraska Hematology Oncology Consultants at Southeast Nebraska Cancer Center

Gamini S. Soori
Ph: 402-991-8070
Email: mwilwerding@mvcc.cc

Norfolk

Carson Cancer Center at Faith Regional Hospital

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

North Platte

Callahan Cancer Center at Great Plains Regional Medical Center

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Omaha

CCOP - Missouri Valley Cancer Consortium

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Oncology Hematology West PC

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Oncology Hematology West, PC - Omaha Bergan

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Scottsbluff

Cancer Treatment Center at Regional West Medical Center

Gamini S. Soori
Ph: 402-991-8070ext202
Email: mwilwerding@mvcc.cc

Nevada
Henderson

21st Century Oncology - Henderson

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Henderson

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada-Southeast Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center - Henderson

John Allan Ellerton
Ph: 702-384-0013

Las Vegas

21st Century Oncology - Fort Apache

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Sunrise

John Allan Ellerton
Ph: 702-384-0013

21st Century Oncology - Vegas Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Fort Apache

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Shadow

John Allan Ellerton
Ph: 702-384-0013

Cancer and Blood Specialists-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Cancer Institute of Nevada at Summerlin Hospital Medical Center

John Allan Ellerton
Ph: 702-384-0013

Cancer Therapy and Integrative Medicine

John Allan Ellerton
Ph: 702-384-0013

CCOP - Nevada Cancer Research Foundation

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Northwest

John Allan Ellerton
Ph: 702-384-0013

Comprehensive Cancer Centers of Nevada - Southwest

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

Las Vegas Cancer Center-Medical Center

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Downtown Location

John Allan Ellerton
Ph: 702-384-0013

Radiation Oncology Centers of Las Vegas - Eastern Location

John Allan Ellerton
Ph: 702-384-0013

University Medical Center of Southern Nevada

John Allan Ellerton
Ph: 702-384-0013

New Hampshire
Concord

New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care

Douglas Jay Weckstein
Ph: 603-224-2556

Dover

Seacoast Cancer Center at Wentworth - Douglass Hospital

Barbara Shea
Ph: 603-740-2150

Hooksett

New Hampshire Oncology - Hematology, PA - Hooksett

Douglas Jay Weckstein
Ph: 603-224-2556

Laconia

Lakes Region General Hospital

Jeanna H Walsh
Ph: 800-339-6484

Lebanon

Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center

Gary N Schwartz
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Nashua

Oncology Center at St. Joseph Hospital

Mary Ann Voltz
Ph: 603-880-3408
Email: carcieri@sjh-nh.org

New Jersey
Englewood

Dizzy Gillespie Cancer Institute at Englewood Hospital and Medical Center

Jill S Morrison
Ph: 201-894-3456

Long Branch

Monmouth Medical Center

Seth D Cohen
Ph: 732-923-7689

Mount Holly

Virtua Fox Chase Health Cancer Program at Virtua Memorial Hospital Burlington County

Michael S. Entmacher
Ph: 888-847-8823

Voorhees

Fox Chase Virtua Health Cancer Program at Virtua West Jersey

Michael S. Entmacher
Ph: 888-847-8823

New York
Bronx

Albert Einstein Cancer Center at Albert Einstein College of Medicine

Christine M. Pellegrino
Ph: 718-904-2730
Email: aecc@aecom.yu.edu

Jack D. Weiler Hospital at Montefiore Medical Center - East Campus

Christine M. Pellegrino
Ph: 718-904-2730
Email: aecc@aecom.yu.edu

Montefiore Medical Center

Christine M. Pellegrino
Ph: 718-904-2730
Email: aecc@aecom.yu.edu

Buffalo

Roswell Park Cancer Institute

Ellis G. Levine
Ph: 877-275-7724

Cooperstown

Bassett Healthcare Regional Cancer Program at Mary Imogene Bassett Hospital

Eric Bravin
Ph: 607-547-3073
Email: diana.crean@bassett.org

Manhasset

Don Monti Comprehensive Cancer Center at North Shore University Hospital

Vincent P. Vinciguerra
Ph: 516-562-3467

Middletown

Tucker Center for Cancer Care at Orange Regional Medical Center

Jeffrey M. Stewart
Ph: 845-342-7609

New Hyde Park

Long Island Jewish Medical Center

Vincent P. Vinciguerra
Ph: 516-562-3467

Monter Cancer Center of the North Shore-LIJ Health System

Vincent P. Vinciguerra
Ph: 516-562-3467

New York

Beth Israel Medical Center - Petrie Division

Paula Klein
Ph: 212-367-1729

Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center

Dawn Hershman
Ph: 212-305-8615

St. Luke's - Roosevelt Hospital Center - St.Luke's Division

Paula Klein
Ph: 212-367-1729

Rochester

Lipson Cancer and Blood Center at Rochester General Hospital

Peter Bushunow
Ph: 585-922-3536
Email: tia.derosa@rochestergeneral.org

White Plains

Dickstein Cancer Treatment Center at White Plains Hospital Center

Karen B Green
Ph: 914-681-2290

North Carolina
Clinton

Southeastern Medical Oncology Center-Clinton

James N. Atkins
Ph: 919-580-0000

Goldsboro

Southeastern Medical Oncology Center - Goldsboro

James N. Atkins
Ph: 919-580-0000

Wayne Memorial Hospital, Incorporated

James N. Atkins
Ph: 919-580-0000

Hendersonville

Comprehensive Cancer Center at Pardee Hospital

James E. Radford
Ph: 828-696-4716

Hendersonville Hematology and Oncology

James E. Radford
Ph: 828-696-4716

Jacksonville

Southeastern Medical Oncology Center-Jacksonville

James N. Atkins
Ph: 919-580-0000

Leland

Cape Fear Cancer Specialists-Leland

Cyrus A. Kotwall
Ph: 910-342-3000
Email: cancer.research@nhrmc.org

Wilmington

Cape Fear Cancer Specialists

Cyrus A. Kotwall
Ph: 910-342-3000
Email: cancer.research@nhrmc.org

Zimmer Cancer Center at New Hanover Regional Medical Center

Cyrus A. Kotwall
Ph: 910-342-3000
Email: cancer.research@nhrmc.org

Wilson

Southeastern Medical Oncology Center - Wilson

James N. Atkins
Ph: 919-580-0000

North Dakota
Bismarck

Medcenter One Hospital Cancer Care Center

Preston D. Steen
Ph: 701-234-6161

Fargo

Roger Maris Cancer Center at MeritCare Hospital

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Ph: 701-234-6161

Sanford Clinic North-Fargo

Preston D. Steen
Ph: 701-234-6161

Minot

Trinity CancerCare Center

Stephen N Makoni
Ph: 800-862-0005

Ohio
Belpre

Strecker Cancer Center-Belpre

J. Philip Kuebler
Ph: 614-566-3275

Canton

Mercy Cancer Center at Mercy Medical Center

Mitchell Haut
Ph: 888-293-4673

Centerville

Miami Valley Hospital South

Howard M. Gross
Ph: 937-775-1350

Chillicothe

Adena Regional Medical Center

J. Philip Kuebler
Ph: 614-566-3275

Cincinnati

Oncology Hematology Care Inc - Western Hills

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Anderson

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Blue Ash

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Kenwood

Howard M. Gross
Ph: 937-775-1350

Oncology Hematology Care, Incorporated - Mt. Auburn/Taft Road

Howard M. Gross
Ph: 937-775-1350

Cleveland

MetroHealth Cancer Care Center at MetroHealth Medical Center

Bruce J. Averbook
Ph: 216-778-8526
Email: kbauchens@metrohealth.org

Columbus

Columbus Oncology Associates, Incorporated

J. Philip Kuebler
Ph: 614-566-3275

Doctors Hospital at Ohio Health

J. Philip Kuebler
Ph: 614-566-3275

Grant Medical Center Cancer Care

J. Philip Kuebler
Ph: 614-566-3275

Mount Carmel Health - West Hospital

J. Philip Kuebler
Ph: 614-566-3275

Riverside Methodist Hospital Cancer Care

J. Philip Kuebler
Ph: 614-566-3275

Zangmeister Center

J. Philip Kuebler
Ph: 614-566-3275

Dayton

David L. Rike Cancer Center at Miami Valley Hospital

Howard M. Gross
Ph: 937-775-1350

Good Samaritan Hospital

Howard M. Gross
Ph: 937-775-1350

Samaritan North Cancer Care Center

Howard M. Gross
Ph: 937-775-1350

Delaware

Delaware Health Center

J. Philip Kuebler
Ph: 614-566-3275

Delaware Radiation Oncology

J. Philip Kuebler
Ph: 614-566-3275

Grady Memorial Hospital

J. Philip Kuebler
Ph: 614-566-3275

Fairfield

Oncology Hematology Care, Incorporated - Fairfield Healthplex

Howard M. Gross
Ph: 937-775-1350

Findlay

Blanchard Valley Regional Cancer Center

Howard M. Gross
Ph: 937-775-1350

Franklin

Atrium Medical Center

Howard M. Gross
Ph: 937-775-1350

Greenville

Wayne Hospital

Howard M. Gross
Ph: 937-775-1350

Kettering

Charles F. Kettering Memorial Hospital

Howard M. Gross
Ph: 937-775-1350

Lancaster

Fairfield Medical Center

J. Philip Kuebler
Ph: 614-566-3275

Marietta

Strecker Cancer Center at Marietta Memorial Hospital

J. Philip Kuebler
Ph: 614-566-3275

Maumee

Northwest Ohio Oncology Center

Rex B Mowat
Ph: 800-444-3561

Rex B Mowat
Ph: 800-444-3561

Mount Vernon

Knox Community Hospital

J. Philip Kuebler
Ph: 614-566-3275

Newark

Licking Memorial Cancer Care Program at Licking Memorial Hospital

J. Philip Kuebler
Ph: 614-566-3275

Newark Radiation Oncology

J. Philip Kuebler
Ph: 614-566-3275

Oregon

St. Charles Mercy Hospital

Rex B Mowat
Ph: 800-444-3561

Portsmouth

Southern Ohio Medical Center Cancer Center

J. Philip Kuebler
Ph: 614-566-3275

Springfield

Community Hospital of Springfield and Clark County

J. Philip Kuebler
Ph: 614-566-3275

Toledo

St. Anne Mercy Hospital

Rex B Mowat
Ph: 800-444-3561

Toledo Clinic, Incorporated - Main Clinic

Rex B Mowat
Ph: 800-444-3561

Troy

UVMC Cancer Care Center at Upper Valley Medical Center

Howard M. Gross
Ph: 937-775-1350

Westerville

Mount Carmel St. Ann's Cancer Center

J. Philip Kuebler
Ph: 614-566-3275

Wright-Patterson Afb

United States Air Force Medical Center - Wright-Patterson

Brandon J Cutler
Ph: 937-257-1398

Zanesville

Genesis - Good Samaritan Hospital

J. Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

Oklahoma
Oklahoma City

Stephenson Cancer Center at the University of Oklahoma

Wajeeha Razaq
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Oregon
Clackamas

Clackamas Radiation Oncology Center

Kelly S Perlewitz
Ph: 503-537-1463

Grants Pass

Three Rivers Community Hospital

Charles R. Dibb
Ph: 541-789-6176

Medford

Dubs Cancer Center at Rogue Valley Medical Center

Charles R. Dibb
Ph: 541-789-6176

Providence Cancer Center at PMCC

Charles R. Dibb
Ph: 541-789-6176

Newberg

Providence Newberg Medical Center

Kelly S Perlewitz
Ph: 503-537-1463

Oregon City

Willamette Falls Hospital

Kelly S Perlewitz
Ph: 503-537-1463

Portland

Providence Cancer Center at Providence Portland Medical Center

Kelly S Perlewitz
Ph: 503-537-1463

Providence St. Vincent Medical Center

Kelly S Perlewitz
Ph: 503-537-1463

Pennsylvania
Abington

Rosenfeld Cancer Center at Abington Memorial Hospital

Willard G. Andrews
Ph: 215-481-2402

Bryn Mawr

Bryn Mawr Hospital

Albert S DeNittis
Ph: 866-225-5654

Carlisle

Carlisle Cancer Center

Cristina I. Truica
Ph: 410-601-6120
Email: CTO@hmc.psu.edu

Danville

Geisinger Cancer Institute at Geisinger Health

Victor Gerald Vogel
Ph: 570-271-5251

Erie

Regional Cancer Center - Erie

Christopher R Marsh
Ph: 814-838-0448
Email: mhaynes@trcc.org

Hazleton

Geisinger Hazleton Cancer Center

Victor Gerald Vogel
Ph: 570-271-5251

Hershey

Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center

Cristina I. Truica
Ph: 410-601-6120
Email: CTO@hmc.psu.edu

Lancaster

Lancaster General Hospital

Elizabeth Horenkamp
Ph: 717-544-5511

Lewisburg

Geisinger Medical Oncology at Evangelical Community Hospital

Victor Gerald Vogel
Ph: 570-271-5251

Lewistown

Lewistown Hospital

Victor Gerald Vogel
Ph: 570-271-5251

Media

Riddle Memorial Hospital Cancer Center

Albert S DeNittis
Ph: 866-225-5654

Paoli

Cancer Center of Paoli Memorial Hospital

Albert S DeNittis
Ph: 866-225-5654

Phoenixville

Cancer Center at Phoenixville Hospital

Carl W. Sharer
Ph: 610-983-1908

Pittsburgh

UPMC Cancer Centers

Shannon L Puhalla
Ph: 412-647-2811

Pottsville

Geisinger Medical Oncology-Pottsville

Victor Gerald Vogel
Ph: 570-271-5251

Reading

St. Joseph Medical Center

Marc Rovito
Ph: 610-378-2336
Email: danielward2@catholichealth.net

State College

Geisinger Medical Group - Scenery Park

Victor Gerald Vogel
Ph: 570-271-5251

West Chester

Cancer Center of Chester County

William E. Luginbuhl
Ph: 610-431-5297

West Reading

McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

Terrence P. Cescon
Ph: 610-988-9323

Wilkes-Barre

Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center

Victor Gerald Vogel
Ph: 570-271-5251

Wynnewood

Lankenau Cancer Center at Lankenau Hospital

Albert S DeNittis
Ph: 866-225-5654

Rhode Island
Pawtucket

Memorial Hospital of Rhode Island

Anthony G. Thomas
Ph: 401-729-2700

Providence

Miriam Hospital

Mary Anne Fenton
Ph: 401-444-1488

Rhode Island Hospital Comprehensive Cancer Center

Mary Anne Fenton
Ph: 401-444-1488

Women and Infants Hospital of Rhode Island

Bachir J Sakr
Ph: 401-274-1122

South Carolina
Beaufort

Keyserling Cancer Center at Beaufort Memorial Hospital

Majd Chahin
Ph: 843-522-7819

Florence

McLeod Regional Medical Center

Rajesh Bajaj
Ph: 843-679-7256

Greenville

Cancer Centers of the Carolinas - Faris Road

Jeffrey Kent Giguere
Ph: 864-241-6251

Cancer Centers of the Carolinas - Grove Commons

Jeffrey Kent Giguere
Ph: 864-241-6251

CCOP - Greenville

Jeffrey Kent Giguere
Ph: 864-241-6251

Greenville Memorial Hospital

Jeffrey Kent Giguere
Ph: 864-241-6251

Greenwood

Self Regional Cancer Center at Self Regional Medical Center

Joanna K Metzner-Sadurski
Ph: 864-725-4771

Greer

Cancer Centers of the Carolinas - Greer Radiation Oncology

Jeffrey Kent Giguere
Ph: 864-241-6251

Seneca

Cancer Centers of the Carolinas - Seneca

Jeffrey Kent Giguere
Ph: 864-241-6251

Spartanburg

Cancer Centers of the Carolinas - Spartanburg

Jeffrey Kent Giguere
Ph: 864-241-6251

South Dakota
Aberdeen

Conklin Regional Cancer Center

Richard J. Conklin
Ph: 605-622-5613

Rapid City

Rapid City Regional Hospital

Mark T Schroeder
Ph: 605-716-3982
Email: research@rcrh.org

Sioux Falls

Avera Cancer Institute

Amy K Krie
Ph: 800-657-4377
Email: Jan.Healy@avera.org

Sanford Cancer Center at Sanford USD Medical Center

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Ph: 701-234-6161

Tennessee
Kingsport

Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center

Asheesh Shipstone
Ph: 423-578-8538

Kingsport Hematology-Oncology Associates

Asheesh Shipstone
Ph: 423-578-8538

Virginia
Charlottesville

Martha Jefferson Hospital Cancer Care Center

Erika J Struble
Ph: 434-654-8400

Fredericksburg

Hematology Oncology Associates of Fredericksburg Inc

Mary H Hackney
Ph: 804-628-1939

Norton

Southwest Virginia Regional Cancer Center at Wellmonth Health

Asheesh Shipstone
Ph: 423-578-8538

Richmond

Virginia Commonwealth University Massey Cancer Center

Mary H Hackney
Ph: 804-628-1939

Washington
Longview

Lower Columbia Regional Cancer Center at PeaceHealth-St. John Medical Center

Kelly S Perlewitz
Ph: 503-537-1463

Vancouver

Southwest Washington Medical Center Cancer Center

Kelly S Perlewitz
Ph: 503-537-1463

Wisconsin
Antigo

Langlade Memorial Hospital

Hamied R. Rezazadeh
Ph: 877-405-6866

Appleton

Fox Valley Hematology and Oncology - East Grant Street

William A Conkright
Ph: 920-749-1171

Burlington

Aurora Cancer Care-Burlington

Rubina Qamar
Ph: 888-709-2080

Chippewa Falls

Marshfield Clinic - Chippewa Center

Rezwan Islam
Ph: 715-393-1400

Eau Claire

Marshfield Clinic Cancer Care at Regional Cancer Center

Rezwan Islam
Ph: 715-393-1400

Elkhorn

Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn

Rubina Qamar
Ph: 888-709-2080

Grafton

Aurora Cancer Care-Grafton

Rubina Qamar
Ph: 888-709-2080

Green Bay

Bellin Memorial Hospital

Patrick J Mansky
Ph: 240-566-3584
Email: clinicaltrials@fmh.org

Green Bay Oncology, Limited at St. Mary's Hospital

Brian L Burnette
Ph: 800-432-6049

Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center

Brian L Burnette
Ph: 800-432-6049

St. Mary's Hospital Medical Center - Green Bay

Brian L Burnette
Ph: 800-432-6049

St. Vincent Hospital Regional Cancer Center

Brian L Burnette
Ph: 800-432-6049

Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center

Rubina Qamar
Ph: 888-709-2080

Janesville

Mercy Regional Cancer Center

Robert Delaune
Ph: 800-928-1103

Johnson Creek

UW Cancer Center Johnson Creek

Jim Cleary
Ph: 877-405-6866

Kenosha

Oncology Alliance - Kenosha South

Rubina Qamar
Ph: 888-709-2080

La Crosse

Gundersen Lutheran Center for Cancer and Blood

Kurt Oettel
Ph: 608-775-2385
Email: cancerctr@gundluth.org

Madison

Dean Hematology & Oncology Clinic

Amit Sanyal
Ph: 608-410-2700

University of Wisconsin Paul P. Carbone Comprehensive Cancer Center

Jim Cleary
Ph: 877-405-6866

Manitowoc

Holy Family Memorial Medical Center Cancer Care Center

Brian L Burnette
Ph: 800-432-6049

Marinette

Bay Area Cancer Care Center at Bay Area Medical Center

Brian L Burnette
Ph: 800-432-6049

Vince Lombardi Cancer Clinic - Marinette

Rubina Qamar
Ph: 888-709-2080

Marshfield

Marshfield Clinic - Marshfield Center

Rezwan Islam
Ph: 715-393-1400

Menomonee Falls

Aurora Advanced Healthcare Inc-Menomonee Falls

Rubina Qamar
Ph: 888-709-2080

Mequon

Columbia Saint Mary's Hospital - Ozaukee

Charles H. I. Tiber
Ph: 414-326-2675
Email: clinicaltrials@columbia-stmarys.org

Milwaukee

Aurora Cancer Care-Milwaukee

Rubina Qamar
Ph: 888-709-2080

Aurora Sinai Medical Center

Rubina Qamar
Ph: 888-709-2080

Columbia-Saint Mary's Cancer Care Center

Charles H. I. Tiber
Ph: 414-326-2675
Email: clinicaltrials@columbia-stmarys.org

Oncology Alliance, SC - Milwaukee - South

Rubina Qamar
Ph: 888-709-2080

Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center

Rubina Qamar
Ph: 888-709-2080

Minocqua

Marshfield Clinic - Lakeland Center

Rezwan Islam
Ph: 715-393-1400

Mukwonago

D.N. Greenwald Center

Timothy R Wassenaar
Ph: 262-928-7878

New Richmond

Cancer Center of Western Wisconsin

Joseph W Leach
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Oconomowoc

Regional Cancer Center at Oconomowoc Memorial Hospital

Timothy R Wassenaar
Ph: 262-928-7878

Oconto Falls

Green Bay Oncology, Limited - Oconto Falls

Brian L Burnette
Ph: 800-432-6049

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Rubina Qamar
Ph: 888-709-2080

Racine

Aurora Health Center - Racine

Rubina Qamar
Ph: 888-709-2080

Rhinelander

Ministry Medical Group at Saint Mary's Hospital

Rezwan Islam
Ph: 715-393-1400

Rice Lake

Marshfield Clinic - Indianhead Center

Rezwan Islam
Ph: 715-393-1400

Sheboygan

Saint Nicholas Hospital

Brian L Burnette
Ph: 800-432-6049

Vince Lombardi Cancer Clinic - Sheboygan

Rubina Qamar
Ph: 888-709-2080

Stevens Point

Marshfield Clinic at Saint Michael's Hospital

Rezwan Islam
Ph: 715-393-1400

Sturgeon Bay

Green Bay Oncology, Limited - Sturgeon Bay

Brian L Burnette
Ph: 800-432-6049

Summit

Aurora Medical Center

Rubina Qamar
Ph: 888-709-2080

Two Rivers

Vince Lombardi Cancer Clinic - Two Rivers

Rubina Qamar
Ph: 888-709-2080

Waukesha

Aurora Cancer Care-Waukesha

Rubina Qamar
Ph: 888-709-2080

Waukesha Memorial Hospital Regional Cancer Center

Timothy R Wassenaar
Ph: 262-928-7878

Wausau

Marshfield Clinic - Wausau Center

Rezwan Islam
Ph: 715-393-1400

University of Wisconcin Cancer Center at Aspirus Wausau Hospital

Hamied R. Rezazadeh
Ph: 877-405-6866

Wauwatosa

Oncology Alliance, SC - Milwaukee - West

Rubina Qamar
Ph: 888-709-2080

West Allis

Aurora Women's Pavilion of West Allis Memorial Hospital

Rubina Qamar
Ph: 888-709-2080

Weston

Marshfield Clinic - Weston Center

Rezwan Islam
Ph: 715-393-1400

Wisconsin Rapids

Marshfield Clinic - Wisconsin Rapids Center

Rezwan Islam
Ph: 715-393-1400

Riverview UW Cancer Center at Riverview Hospital

Ron James Kirschling
Ph: 877-405-6866

Wyoming
Cheyenne

Cheyenne Regional Medical Center

Keren Sturtz
Ph: 888-785-6789

Sheridan

Welch Cancer Center at Sheridan Memorial Hospital

Benjamin Thomas Marchello
Ph: 800-648-6274

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01824836
ClinicalTrials.gov processed this data on May 11, 2015

Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.