Enzalutamide with or without Abiraterone Acetate and Prednisone in Treating Patients with Castration-Resistant Metastatic Prostate Cancer

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Basic Trial Information

PhaseTypeStatusAgeTrial IDs
Phase IIIBiomarker/Laboratory analysis, TreatmentActive18 and overA031201
NCI-2013-01737, CALGB-A031201, NCT01949337

Trial Description

Summary

This randomized phase III trial studies enzalutamide to see how well it works compared to enzalutamide, abiraterone acetate, and prednisone in treating patients with prostate cancer that has spread to other places in the body and keeps growing even when the amount of testosterone in the body is reduced to very low levels. Androgens can cause the growth of prostate cancer cells. Drugs, such as enzalutamide, abiraterone acetate, and prednisone, may lessen the amount of androgens made by the body.

Further Study Information

PRIMARY OBJECTIVES:

I. To compare the overall survival of patients with progressive metastatic castration-resistant prostate cancer (CRPC) treated with either a) enzalutamide only or b) enzalutamide with abiraterone (abiraterone acetate) and prednisone.

SECONDARY OBJECTIVES:

I. To assess the grade 3 or higher toxicity profile and compare safety by treatment arm.

II. To assess and compare post-treatment prostate-specific antigen (PSA) declines by treatment arm.

III. To compare radiographic progression free survival defined by Prostate Cancer Working Group 2 (PCWG2), and objective response rate, by treatment arm.

IV. To test for radiographic progression free survival (rPFS) treatment interaction in predicting overall survival.

V. To assess pre- and post-treatment measures of tumor burden and bone activity using sodium fluoride (NaF) positron emission tomography (PET)/computed tomography (CT) and technetium (Tc) methylene diphosphonate (MDP) bone scintigraphy and correlate these measures with overall survival.

VI. To develop and validate prognostic and predictive models of overall survival that include baseline clinical and molecular markers.

TERTIARY OBJECTIVES:

I. To determine whether pre-treatment serum adrenal androgen (SA) levels are prognostic factors of overall survival and to test whether SA levels are predictive factors of overall survival.

II. To evaluate specific pre-treatment ribonucleic acid (RNA) levels as prognostic factors for overall survival (OS), including the 6- and 9-gene signatures, the circulating tumor cells (CTC) RNA profile, and the circulating tumor stem cell RNA profile.

III. To evaluate the predictive ability of specific pre-treatment and post-treatment RNA, levels on the OS and progression free survival (PFS).

IV. To evaluate specific pre-treatment microRNA levels as prognostic factors for OS.

V. To test whether the microRNA are predictive factors for overall survival.

VI. To determine whether pre-treatment angiokine levels are prognostic factors for OS and PFS.

VII. To test whether pretreatment angiokine levels are predictive factors for OS and PFS and to assess whether post-treatment angiokine levels are predictive factors for OS and PFS.

VIII. To investigate a drug by cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1) interaction with respect to overall survival.

IX. To assay candidate variants and loci hypothesized to be associated with other clinical phenotypes (e.g., progression-free survival or toxicity) or other expression quantitative trait loci (eQTLs).

X. To identify specific single-nucleotide polymorphisms (SNPs) and/or copy number variations that are associated with the response to and toxicity associated with therapy.

XI. To define the effect of abiraterone on reducing enzalutamide metabolic clearance (i.e. increasing enzalutamide area under the curve [AUC]) when the drugs are used in combination.

XII. To define the exposure (AUC) toxicity and exposure (AUC) anti-tumor effect relationship, including biomarkers for enzalutamide alone and enzalutamide combined with abiraterone in prostate cancer patients.

XIII. To develop a population pharmacokinetic model for enzalutamide alone and enzalutamide combined with abiraterone taking account of relevant intrinsic and extrinsic factors.

XIV. To determine the intrapatient and interpatient variability of abiraterone exposure (AUC) in prostate cancer patients receiving abiraterone when combined with enzalutamide.

XV. To determine the intra-patient and inter-patient variability of enzalutamide exposure (AUC) in prostate cancer patients receiving enzalutamide alone and abiraterone plus enzalutamide.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM A: Patients receive enzalutamide orally (PO) once daily (QD) on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

ARM B: Patients receive enzalutamide PO QD, abiraterone acetate PO QD, and prednisone PO twice daily (BID) on days 1-28. Courses repeat every 28 days in the absence of disease progression or unacceptable toxicity.

After completion of study treatment, patients are followed up every 12 weeks for 5 years and then every 6 months for 5 years.

Eligibility Criteria

Inclusion Criteria:

Progressive castration-resistant metastatic prostate cancer with histologically or cytologically confirmed adenocarcinoma of the prostate without neuroendocrine differentiation or small cell features

For visceral or extra-nodal lesions to be considered measurable, they must be >= 10 mm in one dimension, using spiral CT

For lymph nodes to be considered measureable (i.e., target or evaluable lesions), they must be >= 20 mm in at least one dimension, using spiral CT

All other lesions, including small lesions (longest diameter < 20 mm with conventional techniques or < 10 mm with spiral CT scan) and truly non-measurable lesions; lesions that are considered non-measurable include bone lesions (only)

Patients with node only disease (i.e. no presence of visceral, extra nodal lesions or bone lesions) must have node(s) that measure >= 15 mm in short axis

Patients must have progressive disease at study entry defined as one or more of the following three criteria that occurred while the patient was on androgen deprivation therapy; for patients enrolling on the basis of soft tissue or bone progression, the baseline scan must show progression relative to a comparison scan; if the comparison scan is not available, the baseline scan report must reference the previous scan to document progression

PSA progression defined by a minimum of two rising PSA levels with an interval of >= 1 week between each determination; patients who received an anti-androgen must have progression documented by a minimum of two rising PSA levels with an interval of >=1 week between each determination such that at least the second of these rises is >= 4 weeks since last flutamide, bicalutamide or nilutamide; the PSA value at the screening should be >= 2 ug/L (2 ng/mL)

Soft tissue disease progression defined by at least 20% increase in the sum of the diameters of target lesions, taking as reference the smallest sum on study (this includes the baseline sum if that is the smallest on study)

Bone disease progression defined by PCWG2 with two or more new lesions on bone scan

No treatment with prior taxane-based chemotherapy for metastatic disease

Patients who received prior taxane-based chemotherapy as neoadjuvant or adjuvant therapy for local disease, or who received taxane-based therapy in the PSA clinical (non-metastatic) state is allowable provided that the total duration of exposure was six cycles or less and chemotherapy was completed more than 6 months prior to registration

Taxane-based chemotherapy that was aborted due to allergic reactions or intolerance to chemotherapy and therefore received 1 cycle of prior therapy is allowable

No prior enzalutamide, abiraterone, or other novel antiandrogen or androgen synthesis inhibitor

No treatment with any of the following for prostate cancer within 4 weeks prior to enrollment:

Hormonal therapy (e.g., androgen receptor [AR] antagonists, 5 alpha reductase inhibitors, estrogens); Note: treatment with bicalutamide and nilutamide within 4 weeks prior to enrollment is not allowed; treatment with flutamide within 4 weeks prior to enrollment is not allowed; treatment with all other gonadotropin-releasing hormone (GnRH) analogues or antagonists is allowed

Chemotherapy

Biologic therapy

Investigational therapy

Immunotherapy

No use of herbal products that may decrease PSA levels within 4 weeks prior to enrollment

No chronic use of systemic steroids greater than the equivalent of 10 mg of prednisone/prednisolone per day within 4 weeks prior to enrollment

No prior use of ketoconazole for greater than 7 days

No prior radiation therapy or radionuclide therapy for the treatment of metastasis within four weeks prior to enrollment

Patients receiving bisphosphonate therapy or denosumab must have been on a stable dose for at least 4 weeks prior to enrollment

Patients must maintain ongoing androgen deprivation therapy with a GnRH analogue, antagonist, or bilateral orchiectomy (i.e., surgical or medical castration)

No known or suspected brain metastases (NOTE: patients with treated epidural disease are allowed)

No planned palliative procedures for alleviation of bone pain such as radiation therapy or surgery

No structurally unstable bone lesions suggesting impending fracture

No history of seizure or any condition that may increase the patient’s seizure risk (e.g., prior cortical stroke, significant brain trauma); no history of transient ischemic attack (TIA) within 12 months of enrollment

No clinically significant cardiovascular disease including:

Myocardial infarction (MI) within 6 months

Uncontrolled angina within 3 months

Congestive heart failure (CHF) with New York Heart Association (NYHA) class 3 or 4, or patients with NYHA class 3 or 4 in the past, unless a screening echocardiogram (echo) or multi gated acquisition scan (MUGA) performed within three months demonstrates an ejection fraction (EF) > 45%

History of clinically significant ventricular arrhythmias (e.g., ventricular tachycardia, ventricular fibrillation, torsades de pointes)

History of Mobitz II second degree or third degree heart block without a permanent pacemaker in place

Hypotension (systolic blood pressure [BP] < 86 mmHg) or bradycardia (< 50 beats per minute [bpm]) at screening

Uncontrolled hypertension (systolic BP > 170 mmHg or diastolic BP > 105 mmHg at screening)

No gastrointestinal (GI) disorder that negatively affects absorption

No major surgery within 4 weeks prior to enrollment

Eastern Cooperative Oncology Group (ECOG) performance status 0-1

Asymptomatic or mildly symptomatic from prostate cancer

A score of 0-1 on Brief Pain Inventory-Short Form (BPI-SF) Question #3 (worst pain in last 24 hours) will be considered asymptomatic, and a score of 2-3 will be considered mildly symptomatic

Granulocytes >= 1,500/uL

Platelet count >= 100,000/uL

Hemoglobin >= 9 g/dL

Creatinine =< 2 x upper limits of normal (ULN)

Bilirubin =< 1.5 x ULN

Aspartate aminotransferase (AST) or alanine aminotransferase (ALT) =< 2 x ULN

Albumin >= 3 g/dl

Testosterone =< 50 ng/dL (1.7 nmol/L)

Trial Contact Information

Trial Lead Organizations / Sponsors / Collaborators

Alliance for Clinical Trials in Oncology

  • National Cancer Institute
Michael J. Morris, Principal Investigator

Trial Sites

U.S.A.

Alabama
Birmingham

University of Alabama at Birmingham Cancer Center

Guru P. Sonpavde
Ph: 205-934-0309

Guru P. Sonpavde
Principal Investigator

Mobile

Southern Cancer Center PC-Providence

Brian Joseph Heller
Ph: 251-380-5298
Email: dr.heller@southerncancercenter.com

Brian Joseph Heller
Principal Investigator

Alaska
Anchorage

Katmai Oncology Group

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Providence Alaska Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Arizona
Scottsdale

Mayo Clinic in Arizona

Alan Haruo Bryce
Ph: 507-538-7623

Alan Haruo Bryce
Principal Investigator

Tucson

The University of Arizona Cancer Center-North Campus

Parminder Singh
Ph: 520-626-9008

Parminder Singh
Principal Investigator

The University of Arizona Cancer Center-Orange Grove Campus

Parminder Singh
Ph: 520-626-9008

Parminder Singh
Principal Investigator

The University of Arizona Medical Center-University Campus

Parminder Singh
Ph: 520-626-9008

Parminder Singh
Principal Investigator

Arkansas
Jonesboro

Fowler Family Center for Cancer Care

Carroll Dean Scroggin
Ph: 870-934-3678
Email: carroll.scroggin@neabc.com

Carroll Dean Scroggin
Principal Investigator

Little Rock

University of Arkansas for Medical Sciences

Konstantinos Arnaoutakis
Ph: 501-686-8274

Konstantinos Arnaoutakis
Principal Investigator

Veteran's Administration Medical Center

Rangaswamy Govindarajan
Ph: 501-686-6342
Email: govindarajanrang@uams.edu

Rangaswamy Govindarajan
Principal Investigator

California
Anaheim

Kaiser Permanente-Anaheim

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Antioch

Kaiser Permanente-Deer Valley Medical Center

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Baldwin Park

Kaiser Permanente-Baldwin Park

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Bellflower

Kaiser Permanente-Bellflower

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Berkeley

Alta Bates Summit Medical Center-Herrick Campus

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Burbank

Providence Saint Joseph Medical Center/Disney Family Cancer Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Duarte

City of Hope Comprehensive Cancer Center

Przemyslaw W. Twardowski
Ph: 800-826-4673
Email: becomingapatient@coh.org

Przemyslaw W. Twardowski
Principal Investigator

Fontana

Kaiser Permanente Hospital

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Fremont

Kaiser Permanente-Fremont

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Fresno

California Cancer Center - North Fresno

Uzair Bashir Chaudhary
Ph: 559-256-9680
Email: uchaudhary@fresno.ucsf.edu

Uzair Bashir Chaudhary
Principal Investigator

Kaiser Permanente

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

University Oncology Associates

Uzair Bashir Chaudhary
Ph: 559-256-9681
Email: uchaudhary@fresno.ucsf.edu

Uzair Bashir Chaudhary
Principal Investigator

Greenbrae

Marin Cancer Care Inc

Peter David Eisenberg
Ph: 415-925-5000
Email: info@marinspecialtycare.com

Peter David Eisenberg
Principal Investigator

Harbor City

Kaiser Permanente - Harbor City

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Irvine

Kaiser Permanente-Irvine

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

La Jolla

UC San Diego Moores Cancer Center

James Michael Randall
Ph: 858-822-5354
Email: cancercto@ucsd.edu

James Michael Randall
Principal Investigator

Loma Linda

Loma Linda University Medical Center

Chien-Shing (C.S.) Chen
Ph: 909-558-0702
Email: cschen@llu.edu

Chien-Shing (C.S.) Chen
Principal Investigator

Los Angeles

Kaiser Permanente Los Angeles Medical Center

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Kaiser Permanente-Cadillac

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Los Angeles County-USC Medical Center

Amir Goldkorn
Ph: 323-865-0451

Amir Goldkorn
Principal Investigator

USC / Norris Comprehensive Cancer Center

Amir Goldkorn
Ph: 323-865-0451

Amir Goldkorn
Principal Investigator

Modesto

Kaiser Permanente-Modesto

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Newport Beach

USC Norris Oncology/Hematology-Newport Beach

Amir Goldkorn
Ph: 323-865-0451

Amir Goldkorn
Principal Investigator

Oakland

Kaiser Permanente-Oakland

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Orange

UC Irvine Health/Chao Family Comprehensive Cancer Center

John Paul Fruehauf
Ph: 877-827-8839
Email: ucstudy@uci.edu

John Paul Fruehauf
Principal Investigator

Palo Alto

Palo Alto Medical Foundation Health Care

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Panorama City

Kaiser Permanente - Panorama City

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Paradise

Feather River Cancer Center

Sam Mazj
Ph: 530-876-7995
Email: haleew@ah.org

Sam Mazj
Principal Investigator

Redwood City

Kaiser Permanente-Redwood City

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Richmond

Kaiser Permanente-Richmond

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Riverside

Kaiser Permanente-Riverside

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Roseville

Kaiser Permanente-Roseville

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Sacramento

Kaiser Permanente - Sacramento

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Kaiser Permanente-South Sacramento

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

University of California Davis Comprehensive Cancer Center

Primo Nery Lara
Ph: 916-734-3089

Primo Nery Lara
Principal Investigator

San Diego

Kaiser Permanente-San Diego Zion

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Naval Medical Center -San Diego

Preston S. Gable
Ph: 619-532-8712

Preston S. Gable
Principal Investigator

Sharp Memorial Hospital

Robert M. Barone
Ph: 858-939-5015

Robert M. Barone
Principal Investigator

San Francisco

Kaiser Permanente-San Francisco

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

UCSF Medical Center-Mission Bay

Terence Ware Friedlander
Ph: 877-827-3222

Terence Ware Friedlander
Principal Investigator

Veterans Affairs Medical Center - San Francisco

Terence Ware Friedlander
Ph: 877-827-3222

Terence Ware Friedlander
Principal Investigator

San Jose

Kaiser Permanente-Santa Teresa-San Jose

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

San Leandro

Kaiser Permanente San Leandro

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

San Marcos

Kaiser Permanente-San Marcos

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

San Rafael

Kaiser Permanente-San Rafael

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Santa Clara

Kaiser Permanente Medical Center - Santa Clara

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Santa Cruz

Palo Alto Medical Foundation-Santa Cruz

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Santa Rosa

Kaiser Permanente-Santa Rosa

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

South San Francisco

Kaiser Permanente-South San Francisco

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Stockton

Kaiser Permanente-Stockton

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Saint Joseph's Medical Center

Ajithkumar Puthillath
Ph: 209-466-2626

Ajithkumar Puthillath
Principal Investigator

Sunnyvale

Palo Alto Medical Foundation-Sunnyvale

Peter Paul Yu
Ph: 415-209-2686
Email: bernicl@sutterhealth.org

Peter Paul Yu
Principal Investigator

Vacaville

Kaiser Permanente Medical Center-Vacaville

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Vallejo

Kaiser Permanente-Vallejo

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Walnut Creek

Kaiser Permanente-Walnut Creek

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Woodland Hills

Kaiser Permanente

Jonathan A. Polikoff
Ph: 626-564-3455

Jonathan A. Polikoff
Principal Investigator

Colorado
Boulder

Rocky Mountain Cancer Centers-Boulder

Keren Sturtz
Ph: 303-777-2642
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Colorado Springs

Memorial Hospital Colorado Springs

Anthony David Elias
Ph: 720-848-0650

Anthony David Elias
Principal Investigator

Denver

Kaiser Permanente-Franklin

Alexander Menter
Ph: 303-649-5480
Email: alex.menter@kp.org

Alexander Menter
Principal Investigator

Durango

Southwest Oncology PC

Keren Sturtz
Ph: 303-777-2642
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Fort Collins

Poudre Valley Hospital

Anthony David Elias
Ph: 720-848-0650

Anthony David Elias
Principal Investigator

Lakewood

Rocky Mountain Cancer Centers-Lakewood

Keren Sturtz
Ph: 303-777-2642
Email: kgeisen@co-cancerresearch.org

Keren Sturtz
Principal Investigator

Connecticut
Greenwich

Greenwich Hospital

Daniel P. Petrylak
Ph: 203-785-5702

Daniel P. Petrylak
Principal Investigator

Hartford

Smilow Cancer Hospital Care Center at Saint Francis

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Middletown

Middlesex Hospital

Susanna Hong
Ph: 860-358-2058

Susanna Hong
Principal Investigator

Norwalk

Norwalk Hospital

Richard C. Frank
Ph: 203-855-3539
Email: jennifer.long@norwalkhealth.org

Richard C. Frank
Principal Investigator

Norwich

Eastern Connecticut Hematology and Oncology Associates

Dennis E. Slater
Ph: 860-886-8362

Dennis E. Slater
Principal Investigator

Stamford

Stamford Hospital/Bennett Cancer Center

Anthony P. Gulati
Ph: 203-325-2535
Email: agulati@stamhealth.org

Anthony P. Gulati
Principal Investigator

West Haven

Veterans Affairs Connecticut Healthcare System-West Haven Campus

Herta Huey-An Chao
Ph: 203-937-3421ext2832

Herta Huey-An Chao
Principal Investigator

District of Columbia
Washington

MedStar Georgetown University Hospital

Nancy Ann Dawson
Ph: 202-444-0381

Nancy Ann Dawson
Principal Investigator

Sibley Memorial Hospital

Emmanuel S. Antonarakis
Ph: 410-955-8804
Email: jhcccro@jhmi.edu

Emmanuel S. Antonarakis
Principal Investigator

Veterans Affairs Medical Center -Washington DC

Anthony Gerard S. Arcenas
Ph: 877-328-2621

Anthony Gerard S. Arcenas
Principal Investigator

Florida
Lakeland

Lakeland Regional Cancer Center

Gameel Byron Hodge
Ph: 863-904-1900

Gameel Byron Hodge
Principal Investigator

Miami Beach

Mount Sinai Medical Center

Michael A. Schwartz
Ph: 305-674-2625
Email: info@msccop.com

Michael A. Schwartz
Principal Investigator

Orlando

Florida Hospital Orlando

Lee M. Zehngebot
Ph: 407-303-5623

Lee M. Zehngebot
Principal Investigator

UF Cancer Center at Orlando Health

Julio Jose Hajdenberg
Ph: 321-841-7246
Email: CancerClinicalTrials@orlandohealth.com

Julio Jose Hajdenberg
Principal Investigator

Pensacola

Sacred Heart Hospital

James F. Watkins
Ph: 850-416-4611
Email: ttamayo@shhpens.org

James F. Watkins
Principal Investigator

Georgia
Atlanta

Northside Hospital

Pradeep Jolly
Ph: 404-303-3355

Pradeep Jolly
Principal Investigator

Columbus

John B Amos Cancer Center

Andrew W. Pippas
Ph: 706-660-6404

Andrew W. Pippas
Principal Investigator

Decatur

Atlanta VA Medical Center

Wayne Bernard Harris
Ph: 404-778-4389
Email: wharr01@emory.edu

Wayne Bernard Harris
Principal Investigator

Macon

Medical Center of Central Georgia

Frederick M. Schnell
Ph: 478-633-1226

Frederick M. Schnell
Principal Investigator

Savannah

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Mark Alexander Taylor
Ph: 912-350-8568

Mark Alexander Taylor
Principal Investigator

Valdosta

South Georgia Medical Center

Samuel N. Ofori
Ph: 229-259-4601
Email: maryann.heddon@sgmc.org

Samuel N. Ofori
Principal Investigator

Hawaii
Aiea

Oncare Hawaii Inc-Pali Momi

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Pali Momi Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Honolulu

Island Urology

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Kaiser Permanente Moanalua Medical Center

Tatjana Kolevska
Ph: 626-564-3455

Tatjana Kolevska
Principal Investigator

Kuakini Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Oncare Hawaii Inc-POB II

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

OnCare Hawaii-Kuakini

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

OnCare Hawaii-Liliha

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Queen's Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Straub Clinic and Hospital

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Tripler Army Medical Center

Jeffrey L. Berenberg
Ph: 808-586-2979
Email: Jeffrey.l.Berenberg.civ@mail.mil

Jeffrey L. Berenberg
Principal Investigator

University of Hawaii Cancer Center

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Lihue

Wilcox Memorial Hospital and Kauai Medical Clinic

Jeffrey L. Berenberg
Ph: 808-586-2979

Jeffrey L. Berenberg
Principal Investigator

Idaho
Boise

Saint Alphonsus Cancer Care Center-Boise

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Post Falls

Kootenai Cancer Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Illinois
Chicago

Advocate Illinois Masonic Medical Center

Mebea Aklilu
Ph: 773-296-5360

Mebea Aklilu
Principal Investigator

Mount Sinai Hospital Medical Center

Pam G. Khosla
Ph: 773-257-5960
Email: suhi@sinai.org

Pam G. Khosla
Principal Investigator

Rush University Medical Center

Nicklas Robert Pfanzelter
Ph: 312-942-3192
Email: clinical_trials@rush.edu

Nicklas Robert Pfanzelter
Principal Investigator

Weiss Memorial Hospital

Stuart A. Krauss
Ph: 773-564-5021
Email: skrauss@vhschicago.com

Stuart A. Krauss
Principal Investigator

Decatur

Cancer Care Center of Decatur

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Decatur Memorial Hospital

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Effingham

Crossroads Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Evanston

NorthShore University HealthSystem-Evanston Hospital

Daniel H. Shevrin
Ph: 847-570-2109

Daniel H. Shevrin
Principal Investigator

Geneva

Northwestern Medicine Cancer Center Delnor

Robert Michael Eisner
Ph: 630-352-5489
Email: Claudine.Gamster@CadenceHealth.org

Robert Michael Eisner
Principal Investigator

Glenview

NorthShore University HealthSystem-Glenbrook Hospital

Daniel H. Shevrin
Ph: 847-570-2109

Daniel H. Shevrin
Principal Investigator

Harvey

Ingalls Memorial Hospital

Mark Farrell Kozloff
Ph: 708-915-4673
Email: clinicaltrials@ingalls.org

Mark Farrell Kozloff
Principal Investigator

Highland Park

NorthShore University HealthSystem-Highland Park Hospital

Daniel H. Shevrin
Ph: 847-570-2109

Daniel H. Shevrin
Principal Investigator

Hines

Hines Veterans Administration Hospital

Elizabeth Henry
Ph: 708-226-4357

Elizabeth Henry
Principal Investigator

Peoria

Illinois CancerCare-Peoria

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Quincy

Quincy Medical Group-Clinic

Raymond P. Smith
Ph: 217-277-3500
Email: rsmith@quincymedgroup.com

Raymond P. Smith
Principal Investigator

River Forest

West Suburban Medical Center

Stuart A. Krauss
Ph: 773-564-5021
Email: skrauss@vhschicago.com

Stuart A. Krauss
Principal Investigator

Rockford

Saint Anthony Medical Center

Shylendra B. Sreenivasappa
Ph: 815-227-2633

Shylendra B. Sreenivasappa
Principal Investigator

Springfield

Memorial Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Urbana

Carle Cancer Center

Vamsi Krishna Vasireddy
Ph: 800-446-5532

Vamsi Krishna Vasireddy
Principal Investigator

Warrenville

Northwestern Medicine Cancer Center Warrenville

Robert Michael Eisner
Ph: 630-315-1918
Email: Claudine.Gamster@CadenceHealth.org

Robert Michael Eisner
Principal Investigator

Indiana
Fort Wayne

Fort Wayne Medical Oncology and Hematology Inc - Jefferson Boulevard

Sreenivasa R. Nattam
Ph: 260-484-8830
Email: ledgar@fwmoh.com

Sreenivasa R. Nattam
Principal Investigator

Fort Wayne Medical Oncology and Hematology Inc-Parkview

Sreenivasa R. Nattam
Ph: 260-484-8830
Email: ledgar@fwmoh.com

Sreenivasa R. Nattam
Principal Investigator

Munster

The Community Hospital

Mohamad Kassar
Ph: 219-836-3349

Mohamad Kassar
Principal Investigator

South Bend

Memorial Hospital of South Bend

Thomas Joseph Reid
Ph: 800-284-7370

Thomas Joseph Reid
Principal Investigator

Iowa
Ames

McFarland Clinic PC-William R Bliss Cancer Center

Joseph James Merchant
Ph: 515-239-2621

Joseph James Merchant
Principal Investigator

Bettendorf

Hematology Oncology Associates-Quad Cities

Shobha R. Chitneni
Ph: 563-344-5459
Email: kedaprile@rccqc.com

Shobha R. Chitneni
Principal Investigator

Clive

Medical Oncology and Hematology Associates-West Des Moines

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Mercy Cancer Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Davenport

Genesis Medical Center - East Campus

George Kovach
Ph: 800-446-6088
Email: werners@genesishealth.com

George Kovach
Principal Investigator

Des Moines

Medical Oncology and Hematology Associates-Laurel

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Mercy Medical Center - Des Moines

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Iowa City

Iowa City VA Healthcare System

Laith Abushahin
Ph: 800-237-1225

Laith Abushahin
Principal Investigator

University of Iowa/Holden Comprehensive Cancer Center

Daniel Alberto Vaena
Ph: 800-237-1225

Daniel Alberto Vaena
Principal Investigator

Mason City

Mercy Medical Center - North Iowa

Steven Robert Snyder
Ph: 641-428-6361
Email: snydersr@mercyhealth.com

Steven Robert Snyder
Principal Investigator

Sioux City

Siouxland Regional Cancer Center

Donald B. Wender
Ph: 712-252-9359
Email: drednew@msn.com

Donald B. Wender
Principal Investigator

West Des Moines

Mercy Medical Center-West Lakes

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Kansas
Chanute

Cancer Center of Kansas - Chanute

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Dodge City

Cancer Center of Kansas - Dodge City

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

El Dorado

Cancer Center of Kansas - El Dorado

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Emporia

Newman Regional Health

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Fort Scott

Cancer Center of Kansas - Fort Scott

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Garden City

Saint Catherine Hospital

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Great Bend

Saint Rose Ambulatory and Surgery Center

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Hays

Hays Medical Center

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Independence

Cancer Center of Kansas-Independence

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Kansas City

The University of Kansas Cancer Center-West

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

University of Kansas Cancer Center

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Kingman

Cancer Center of Kansas-Kingman

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Liberal

Cancer Center of Kansas-Liberal

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Newton

Cancer Center of Kansas - Newton

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Olathe

Olathe Medical Center

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Overland Park

Saint Luke's South Hospital

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

The University of Kansas Cancer Center-Overland Park

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Parsons

Cancer Center of Kansas - Parsons

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Pittsburg

Via Christi Hospital-Pittsburg

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Pratt

Cancer Center of Kansas - Pratt

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Salina

Cancer Center of Kansas - Salina

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Salina Regional Health Center

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Topeka

Saint Francis Hospital and Medical Center - Topeka

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Wellington

Cancer Center of Kansas - Wellington

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Wichita

Cancer Center of Kansas - Main Office

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Cancer Center of Kansas-Wichita Medical Arts Tower

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Winfield

Cancer Center of Kansas - Winfield

Shaker R. Dakhil
Ph: 316-262-4467

Shaker R. Dakhil
Principal Investigator

Kentucky
Lexington

Saint Joseph Hospital East

Mehmet Sitki Copur
Ph: 308-398-5351
Email: mcopur@sfmc-gi.org

Mehmet Sitki Copur
Principal Investigator

Louisiana
Alexandria

Christus Saint Frances Cabrini Hospital

Marc R. Matrana
Ph: 504-842-4533
Email: mamatrana@ochsner.org

Marc R. Matrana
Principal Investigator

Baton Rouge

Hematology/Oncology Clinic LLP

Hana F. Safah
Ph: 504-988-2368
Email: hsafah@tulane.edu

Hana F. Safah
Principal Investigator

Ochsner Health Center-Summa

Marc R. Matrana
Ph: 888-562-4763

Marc R. Matrana
Principal Investigator

Kenner

Ochsner Medical Center Kenner

Marc R. Matrana
Ph: 888-562-4763

Marc R. Matrana
Principal Investigator

Metairie

East Jefferson General Hospital

Augusto C. Ochoa
Ph: 504-210-2970
Email: emede1@lsuhsc.edu

Augusto C. Ochoa
Principal Investigator

New Orleans

Ochsner Medical Center Jefferson

Marc R. Matrana
Ph: 888-562-4763

Marc R. Matrana
Principal Investigator

Tulane University Health Sciences Center

Hana F. Safah
Ph: 504-988-6121

Hana F. Safah
Principal Investigator

Maine
Augusta

Harold Alfond Center for Cancer Care

Thomas H. Openshaw
Ph: 207-973-7807
Email: topenshaw@emh.org

Thomas H. Openshaw
Principal Investigator

Bangor

Eastern Maine Medical Center

Thomas H. Openshaw
Ph: 207-973-7807
Email: topenshaw@emh.org

Thomas H. Openshaw
Principal Investigator

Brewer

Lafayette Family Cancer Center-EMMC

Thomas H. Openshaw
Ph: 207-973-7807
Email: topenshaw@emh.org

Thomas H. Openshaw
Principal Investigator

Rockport

Penobscot Bay Medical Center

Thomas H. Openshaw
Ph: 207-973-7807
Email: topenshaw@emh.org

Thomas H. Openshaw
Principal Investigator

Maryland
Baltimore

Johns Hopkins University/Sidney Kimmel Cancer Center

Emmanuel S. Antonarakis
Ph: 410-955-8804
Email: jhcccro@jhmi.edu

Emmanuel S. Antonarakis
Principal Investigator

Frederick

Frederick Memorial Hospital

Elhamy D. Eskander
Ph: 240-566-3584
Email: clinicaltrials@fmh.org

Elhamy D. Eskander
Principal Investigator

Olney

Montgomery General Hospital-Olney

Nancy Ann Dawson
Ph: 202-444-0381

Nancy Ann Dawson
Principal Investigator

Westminster

William E Kahlert Regional Cancer Center/Sinai Hospital

Flavio Wainberg Kruter
Ph: 410-871-6400
Email: fkruter@carrollhospitalcenter.org

Flavio Wainberg Kruter
Principal Investigator

Massachusetts
Boston

Tufts Medical Center

Paul Mathew
Ph: 617-636-5000
Email: ContactUsCancerCenter@TuftsMedicalCenter.org

Paul Mathew
Principal Investigator

Fitchburg

Simonds-Sinon Regional Cancer Center

William V. Walsh
Ph: 508-856-3216
Email: cancer.research@umassmed.edu

William V. Walsh
Principal Investigator

Newton

Newton-Wellesley Hospital

Caroline Cole Block
Ph: 617-658-6001
Email: cblock@partners.org

Caroline Cole Block
Principal Investigator

Springfield

Baystate Medical Center

Leslie Marion Howard
Ph: 413-794-3565
Email: tamara.wrenn@baystatehealth.org

Leslie Marion Howard
Principal Investigator

Worcester

University of Massachusetts Medical School

William V. Walsh
Ph: 508-856-3216
Email: cancer.research@umassmed.edu

William V. Walsh
Principal Investigator

Michigan
Ann Arbor

Saint Joseph Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

University of Michigan Comprehensive Cancer Center

Maha H. A. Hussain
Ph: 800-865-1125
Email: mahahuss@umich.edu

Maha H. A. Hussain
Principal Investigator

Detroit

Henry Ford Hospital

Robert Anthony Chapman
Ph: 313-916-1784

Robert Anthony Chapman
Principal Investigator

Wayne State University/Karmanos Cancer Institute

Ulka N. Vaishampayan
Ph: 313-576-9363

Ulka N. Vaishampayan
Principal Investigator

Escanaba

Green Bay Oncology - Escanaba

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Grand Rapids

Mercy Health Saint Mary's

Kathleen J. Yost
Ph: 616-954-2116
Email: connie.szczepanek@grcop.org

Kathleen J. Yost
Principal Investigator

Spectrum Health at Butterworth Campus

Kathleen J. Yost
Ph: 616-954-2116
Email: connie.szczepanek@grcop.org

Kathleen J. Yost
Principal Investigator

Iron Mountain

Green Bay Oncology - Iron Mountain

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Lansing

Sparrow Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Livonia

Saint Mary Mercy Hospital

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Reed City

Spectrum Health Reed City Hospital

Kathleen J. Yost
Ph: 616-954-2116
Email: connie.szczepanek@grcop.org

Kathleen J. Yost
Principal Investigator

Saginaw

Saint Mary's of Michigan

Philip J. Stella
Ph: 734-712-4673

Philip J. Stella
Principal Investigator

Traverse City

Munson Medical Center

Kathleen J. Yost
Ph: 616-954-2116
Email: connie.szczepanek@grcop.org

Kathleen J. Yost
Principal Investigator

Minnesota
Bemidji

Sanford Clinic North-Bemidgi

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Burnsville

Fairview Ridges Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Coon Rapids

Mercy Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Duluth

Essentia Health Cancer Center

Bret E.B. Friday
Ph: 888-203-7267

Bret E.B. Friday
Principal Investigator

Saint Luke's Hospital of Duluth

Basem Said Goueli
Ph: 218-249-3083
Email: kdean@slhduluth.com

Basem Said Goueli
Principal Investigator

Fridley

Unity Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Mankato

Mayo Clinic Health Systems-Mankato

Alan Haruo Bryce
Ph: 480-301-4675
Email: bryce.alan@mayo.edu

Alan Haruo Bryce
Principal Investigator

Maplewood

Minnesota Oncology Hematology PA-Maplewood

Daniel M. Anderson
Ph: 952-993-1550
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Saint John's Hospital - Healtheast

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Minneapolis

Abbott-Northwestern Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Health Partners Inc

Daniel M. Anderson
Ph: 952-993-1550
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Hennepin County Medical Center

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Minneapolis Veterans Medical Center

Sharon Davis Luikart
Ph: 612-725-2149
Email: sharon.luikart@va.gov

Sharon Davis Luikart
Principal Investigator

Rochester

Mayo Clinic

Alan Haruo Bryce
Ph: 480-301-4675
Email: bryce.alan@mayo.edu

Alan Haruo Bryce
Principal Investigator

Saint Cloud

Coborn Cancer Center at Saint Cloud Hospital

Donald James Jurgens
Ph: 877-229-4907
Email: coborncancercenter@centracare.com

Donald James Jurgens
Principal Investigator

Saint Louis Park

Park Nicollet Clinic - Saint Louis Park

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Saint Paul

Regions Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Shakopee

Saint Francis Regional Medical Center

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Stillwater

Lakeview Hospital

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Woodbury

Minnesota Oncology and Hematology PA-Woodbury

Daniel M. Anderson
Ph: 952-993-1517
Email: MMCCOP@parknicollet.com

Daniel M. Anderson
Principal Investigator

Mississippi
Corinth

The West Clinic - Corinth

Bradley G. Somer
Ph: 901-685-2969
Email: bsomer@westclinic.com

Bradley G. Somer
Principal Investigator

Missouri
Cape Girardeau

Saint Francis Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Southeast Cancer Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Chesterfield

Saint Luke's Hospital

Donald F. Busiek
Ph: 314-576-2378
Email: Donald.Busiek@stlukes-stl.com

Donald F. Busiek
Principal Investigator

Creve Coeur

Barnes-Jewish West County Hospital

Joel Picus
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Joel Picus
Principal Investigator

Jefferson City

Capital Region Medical Center-Goldschmidt Cancer Center

James Lloyd Wade
Ph: 217-876-6606
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Kansas City

Kansas City Veterans Affairs Medical Center

Peter J. Van Veldhuizen
Ph: 913-498-7470
Email: petervan1000@gmail.com

Peter J. Van Veldhuizen
Principal Investigator

Research Medical Center

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

Saint Luke's Hospital of Kansas City

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

The University of Kansas Cancer Center-North

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

The University of Kansas Cancer Center-South

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Truman Medical Center

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Lee's Summit

Saint Luke's East - Lee's Summit

Rakesh Gaur
Ph: 816-932-2677
Email: SLCIResearch1@saint-lukes.org

Rakesh Gaur
Principal Investigator

The University of Kansas Cancer Center-Lee's Summit

Priyanka Sharma
Ph: 913-588-7727
Email: ctnursenav@kumc.edu

Priyanka Sharma
Principal Investigator

Saint Louis

Mercy Hospital Saint Louis

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Missouri Baptist Medical Center

James Lloyd Wade
Ph: 217-876-4740
Email: kcheek@dmhhs.org

James Lloyd Wade
Principal Investigator

Washington University School of Medicine

Joel Picus
Ph: 800-600-3606
Email: info@siteman.wustl.edu

Joel Picus
Principal Investigator

Springfield

Mercy Hospital Springfield

Jay W. Carlson
Ph: 800-821-7532

Jay W. Carlson
Principal Investigator

Montana
Billings

Saint Vincent Healthcare

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Bozeman

Bozeman Deaconess Hospital

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Butte

Saint James Community Hospital and Cancer Treatment Center

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Great Falls

Benefis Healthcare- Sletten Cancer Institute

Benjamin T. Marchello
Ph: 800-648-6274

Benjamin T. Marchello
Principal Investigator

Kalispell

Kalispell Regional Medical Center

Benjamin T. Marchello
Ph: 406-237-5470
Email: bmarchello@mtcancer.org

Benjamin T. Marchello
Principal Investigator

Nebraska
Grand Island

CHI Health Saint Francis

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Kearney

CHI Health Good Samaritan

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Lincoln

Nebraska Hematology and Oncology

Gamini S. Soori
Ph: 402-991-8070
Email: gsoori@mvcc.cc

Gamini S. Soori
Principal Investigator

Southeast Nebraska Cancer Center

Gamini S. Soori
Ph: 402-991-8070
Email: gsoori@mvcc.cc

Gamini S. Soori
Principal Investigator

Omaha

Nebraska Methodist Hospital

Ralph J. Hauke
Ph: 402-343-8511
Email: rhauke@nebraskacancer.com

Ralph J. Hauke
Principal Investigator

Nevada
Las Vegas

Comprehensive Cancer Centers of Nevada

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

Comprehensive Cancer Centers of Nevada - Central Valley

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-San Martin

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

John Allan Ellerton
Ph: 702-384-0013

John Allan Ellerton
Principal Investigator

New Hampshire
Concord

New Hampshire Oncology Hematology PA-Concord

Douglas J. Weckstein
Ph: 603-224-2556

Douglas J. Weckstein
Principal Investigator

Dover

Wentworth-Douglass Hospital

Henry Leo Sonneborn
Ph: 603-740-2150

Henry Leo Sonneborn
Principal Investigator

Hooksett

New Hampshire Oncology Hematology PA-Hooksett

Douglas J. Weckstein
Ph: 603-224-2556

Douglas J. Weckstein
Principal Investigator

Laconia

LRGHealthcare-Lakes Region General Hospital

Charles H. Catcher
Ph: 800-339-6484

Charles H. Catcher
Principal Investigator

Lebanon

Dartmouth Hitchcock Medical Center

Sergey Devitskiy
Ph: 800-639-6918
Email: cancer.research.nurse@dartmouth.edu

Sergey Devitskiy
Principal Investigator

Manchester

Norris Cotton Cancer Center-Manchester

Sergey Devitskiy
Ph: 603-650-7791
Email: cancer.research.nurse@dartmouth.edu

Sergey Devitskiy
Principal Investigator

Nashua

Norris Cotton Cancer Center Nashua

Sergey Devitskiy
Ph: 603-650-7791
Email: cancer.research.nurse@dartmouth.edu

Sergey Devitskiy
Principal Investigator

Portsmouth

Portsmouth Regional Hospital

Christine Wasilewski
Ph: 603-433-5226

Christine Wasilewski
Principal Investigator

New Jersey
Basking Ridge

Memorial Sloan Kettering Cancer Center at Basking Ridge

Michael J. Morris
Ph: 212-988-0701
Email: morrism@mskcc.org

Michael J. Morris
Principal Investigator

East Orange

Veterans Adminstration New Jersey Health Care System

Victor Tsu-Shih Chang
Ph: 800-475-2336
Email: patricia.goyer@med.va.gov

Victor Tsu-Shih Chang
Principal Investigator

Hackensack

Hackensack University Medical Center

Samuel A. Goldlust
Ph: 201-996-2879

Samuel A. Goldlust
Principal Investigator

Mount Holly

Virtua Memorial

James W. Lee
Ph: 888-847-8823

James W. Lee
Principal Investigator

Paramus

The Valley Hospital-Luckow Pavilion

Eli D. Kirshner
Ph: 201-634-5792

Eli D. Kirshner
Principal Investigator

Voorhees

Virtua Voorhees

James W. Lee
Ph: 888-847-8823

James W. Lee
Principal Investigator

Westwood

Valley Health System-Hematology/Oncology

Eli D. Kirshner
Ph: 201-634-5792

Eli D. Kirshner
Principal Investigator

New Mexico
Albuquerque

University of New Mexico Cancer Center

Richard C. Lauer
Ph: 505-272-6972

Richard C. Lauer
Principal Investigator

Las Cruces

Memorial Medical Center - Las Cruces

Richard C. Lauer
Ph: 505-272-6972

Richard C. Lauer
Principal Investigator

Santa Fe

Christus Saint Vincent Regional Cancer Center

Richard C. Lauer
Ph: 505-272-6972

Richard C. Lauer
Principal Investigator

New York
Bronx

Bronx Veterans Administration Medical Center

Yeun-Hee Anna Park
Ph: 212-305-8615

Yeun-Hee Anna Park
Principal Investigator

Montefiore Medical Center - Moses Campus

Benjamin Adam Gartrell
Ph: 718-798-7474
Email: aecc@aecom.yu.edu

Benjamin Adam Gartrell
Principal Investigator

Montefiore Medical Center-Einstein Campus

Benjamin Adam Gartrell
Ph: 718-798-7474
Email: aecc@aecom.yu.edu

Benjamin Adam Gartrell
Principal Investigator

Brooklyn

Maimonides Medical Center

Kevin Becker
Ph: 718-765-2500

Kevin Becker
Principal Investigator

Buffalo

Roswell Park Cancer Institute

Saby George
Ph: 716-845-8008
Email: saby.george@roswellpark.org

Saby George
Principal Investigator

Veterans Affairs Western New York Health Care System-Buffalo

Lynn M. Steinbrenner
Ph: 716-862-3191

Lynn M. Steinbrenner
Principal Investigator

Commack

Memorial Sloan Kettering Cancer Center Commack

Michael J. Morris
Ph: 212-988-0701
Email: morrism@mskcc.org

Michael J. Morris
Principal Investigator

Elmira

Arnot Ogden Medical Center/Falck Cancer Center

William Thomas Muuse
Ph: 607-271-7000

William Thomas Muuse
Principal Investigator

New Hyde Park

North Shore-LIJ Health System/Center for Advanced Medicine

Xinhua Zhu
Ph: 516-734-8954
Email: xzhu1@nshs.edu

Xinhua Zhu
Principal Investigator

New York

Columbia University/Herbert Irving Cancer Center

Emerson A. Lim
Ph: 212-305-8615

Emerson A. Lim
Principal Investigator

Laura and Isaac Perlmutter Cancer Center at NYU Langone

Arjun V. Balar
Ph: 212-731-5459
Email: prmc.coordinator@nyumc.org

Arjun V. Balar
Principal Investigator

Memorial Sloan-Kettering Cancer Center

Michael J. Morris
Ph: 212-988-0701
Email: morrism@mskcc.org

Michael J. Morris
Principal Investigator

Weill Medical College of Cornell University

Scott Tadashi Tagawa
Ph: 212-746-1848

Scott Tadashi Tagawa
Principal Investigator

Rochester

University of Rochester

Jonathan Willmann Friedberg
Ph: 585-275-5830

Jonathan Willmann Friedberg
Principal Investigator

Rockville Centre

Memorial Sloan-Kettering Cancer Center Rockville Centre

Michael J. Morris
Ph: 212-988-0701
Email: morrism@mskcc.org

Michael J. Morris
Principal Investigator

Sleepy Hollow

Memorial Sloan-Kettering Cancer Center Sleepy Hollow

Michael J. Morris
Ph: 212-988-0701
Email: morrism@mskcc.org

Michael J. Morris
Principal Investigator

Syracuse

State University of New York Upstate Medical University

Sam Benjamin
Ph: 315-464-5476

Sam Benjamin
Principal Investigator

West Harrison

Memorial Sloan-Kettering Cancer Center West Harrison

Michael J. Morris
Ph: 212-988-0701
Email: morrism@mskcc.org

Michael J. Morris
Principal Investigator

North Carolina
Asheboro

Randolph Hospital

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Burlington

Cone Health Cancer Center at Alamance Regional

James Mitchell Granfortuna
Ph: 336-832-0770
Email: james.granfortuna@conehealth.com

James Mitchell Granfortuna
Principal Investigator

Chapel Hill

UNC Lineberger Comprehensive Cancer Center

Young E. Whang
Ph: 877-668-0683
Email: cancerclinicaltrials@med.unc.edu

Young E. Whang
Principal Investigator

Charlotte

Novant Health Presbyterian Medical Center

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Oncology Specialists of Charlotte

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Southern Oncology Specialists-Charlotte

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Durham

Duke University Medical Center

Jeffrey Crawford
Ph: 888-275-3853

Jeffrey Crawford
Principal Investigator

Durham Veterans Affairs Medical Center

Daphne R. Friedman
Ph: 919-286-6926
Email: John.Whited@va.gov

Daphne R. Friedman
Principal Investigator

Goldsboro

Wayne Memorial Hospital

James N. Atkins
Ph: 919-580-0000

James N. Atkins
Principal Investigator

Greensboro

Cone Health Cancer Center

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Huntersville

Lake Norman Hematology Oncology Specialists-Huntersville

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Southern Oncology Specialists-Huntersville

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Kernersville

Novant Health Oncology Specialists-Kernersville

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Kinston

Kinston Medical Specialists PA

Peter Robins Watson
Ph: 252-559-2200

Peter Robins Watson
Principal Investigator

Lexington

Novant Health Oncology Specialists-Davidson County

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Matthews

Novant Health Cancer Specialists-Matthews

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Mooresville

Lake Norman Hematology Oncology Specialists-Mooresville

Justin Peter Favaro
Ph: 704-384-5369

Justin Peter Favaro
Principal Investigator

Mount Airy

Novant Health Oncology Specialists-Mount Airy

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Reidsville

Annie Penn Memorial Hospital

James Mitchell Granfortuna
Ph: 336-832-0821

James Mitchell Granfortuna
Principal Investigator

Salisbury

Carolina Oncology Associates PA

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Veterans Administration Medical Center.

Michael Moses Goodman
Ph: 336-713-6771
Email: mgoodman@wakehealth.edu

Michael Moses Goodman
Principal Investigator

Stateville

Novant Health Oncology Specialists-Statesville

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Wilkesboro

Novant Health Oncology Specialists-Wilkesboro

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Winston-Salem

Novant Health Forsyth Medical Center

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Novant Health Oncology Specialists

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

Wake Forest University Health Sciences

Rhonda Lynn Bitting
Ph: 336-713-6771

Rhonda Lynn Bitting
Principal Investigator

Winston-Salem Health Care

Judith Owen Hopkins
Ph: 336-277-8887

Judith Owen Hopkins
Principal Investigator

North Dakota
Bismarck

Sanford Bismarck Medical Center

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Fargo

Sanford Clinic North-Fargo

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Sanford Medical Center-Fargo

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Grand Forks

Altru Cancer Center

Grant Richard Seeger
Ph: 701-780-1729
Email: gseeger@altru.org

Grant Richard Seeger
Principal Investigator

Minot

Trinity Cancer Care Center

Patanit Watanaboonyakhet
Ph: 800-862-0005

Patanit Watanaboonyakhet
Principal Investigator

Ohio
Akron

Summa Akron City Hospital/Cooper Cancer Center

Jennifer Eileen Payne
Ph: 330-375-6101

Jennifer Eileen Payne
Principal Investigator

Barberton

Summa Barberton Hospital

Jennifer Eileen Payne
Ph: 330-375-6101

Jennifer Eileen Payne
Principal Investigator

Beachwood

UHHS-Chagrin Highlands Medical Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Centerville

Dayton Physicians LLC-Miami Valley South

Howard M. Gross
Ph: 937-832-5344
Email: hgross@woh.rr.com

Howard M. Gross
Principal Investigator

Chardon

Geaugra Hospital

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Cincinnati

University of Cincinnati

Nilesh Narsingrao Patil
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Nilesh Narsingrao Patil
Principal Investigator

Cleveland

Case Western Reserve University

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Cleveland Clinic Cancer Center/Fairview Hospital

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Cleveland Clinic Foundation

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

MetroHealth Medical Center

Bruce J. Averbook
Ph: 216-778-8526
Email: kbauchens@metrohealth.org

Bruce J. Averbook
Principal Investigator

Columbus

Mount Carmel Health Center West

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Ohio State University Comprehensive Cancer Center

Amir Mortazavi
Ph: 800-293-5066
Email: Jamesline@osumc.edu

Amir Mortazavi
Principal Investigator

The Mark H Zangmeister Center

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Dayton

Good Samaritan Hospital - Dayton

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Miami Valley Hospital

Howard M. Gross
Ph: 937-832-5344
Email: hgross@woh.rr.com

Howard M. Gross
Principal Investigator

Samaritan North Health Center

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Elyria

Hematology Oncology Center Incorporated

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Mercy Cancer Center-Elyria

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Findlay

Armes Family Cancer Center

Howard M. Gross
Ph: 937-832-5344
Email: hgross@woh.rr.com

Howard M. Gross
Principal Investigator

Blanchard Valley Hospital

Howard M. Gross
Ph: 937-775-1350

Howard M. Gross
Principal Investigator

Orion Cancer Care

Howard M. Gross
Ph: 937-832-5344
Email: hgross@woh.rr.com

Howard M. Gross
Principal Investigator

Independence

Cleveland Clinic Cancer Center Independence

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Kettering

Greater Dayton Cancer Center

Howard M. Gross
Ph: 937-832-5344
Email: hgross@woh.rr.com

Howard M. Gross
Principal Investigator

Mansfield

Cleveland Clinic Cancer Center Mansfield

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Maumee

Toledo Clinic Cancer Centers-Maumee

Rex B. Mowat
Ph: 800-444-3561

Rex B. Mowat
Principal Investigator

Mayfield Heights

Hillcrest Hospital Cancer Center

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Ireland Cancer Center Landerbrook Health Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Medina

Summa Health Center at Lake Medina

Jennifer Eileen Payne
Ph: 330-375-6101

Jennifer Eileen Payne
Principal Investigator

Mentor

Lake University Ireland Cancer Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Middleburg Heights

Southwest General Health Center Ireland Cancer Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Parma

University Hospitals Parma Medical Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Portsmouth

Southern Ohio Medical Center

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Sandusky

Ireland Cancer Center at Firelands Regional Medical Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

North Coast Cancer Care

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Strongsville

Cleveland Clinic Cancer Center Strongsville

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Toledo

Toledo Clinic Cancer Centers-Toledo

Rex B. Mowat
Ph: 800-444-3561

Rex B. Mowat
Principal Investigator

University of Toledo

Samay Jain
Ph: 419-383-6583

Samay Jain
Principal Investigator

Wadsworth

University Hospitals Sharon Health Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Warrensville Heights

South Pointe Hospital

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

West Chester

University Pointe

Nilesh Narsingrao Patil
Ph: 513-558-4553
Email: uchealthnews@uc.edu

Nilesh Narsingrao Patil
Principal Investigator

Westerville

Saint Ann's Hospital

John Philip Kuebler
Ph: 614-488-2745
Email: sheree@columbusccop.org

John Philip Kuebler
Principal Investigator

Westlake

UHHS-Westlake Medical Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

UH-Seidman Cancer Center at Saint John Medical Center

Matthew Morrissey Cooney
Ph: 800-641-2422

Matthew Morrissey Cooney
Principal Investigator

Wooster

Cleveland Clinic Wooster Family Health and Surgery Center

Anjali S. Advani
Ph: 866-223-8100

Anjali S. Advani
Principal Investigator

Wright-Patterson Afb

Wright-Patterson Medical Center

Susannah Catherine Cooper
Ph: 937-656-1615
Email: susannah.cooper@us.af.mil

Susannah Catherine Cooper
Principal Investigator

Oklahoma
Lawton

Cancer Centers of Southwest Oklahoma Research

Nadim Fouad Nimeh
Ph: 877-231-4440

Nadim Fouad Nimeh
Principal Investigator

Oklahoma City

Mercy Hospital Oklahoma City

Vikki A. Canfield
Ph: 405-751-4343

Vikki A. Canfield
Principal Investigator

University of Oklahoma Health Sciences Center

Kelly L. Stratton
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Kelly L. Stratton
Principal Investigator

Tulsa

Oklahoma Cancer Specialists and Research Institute-Tulsa

Kelly L. Stratton
Ph: 405-271-4272
Email: julie-traylor@ouhsc.edu

Kelly L. Stratton
Principal Investigator

Oregon
Corvallis

Good Samaritan Hospital

Kimberly A. McGregor
Ph: 888-823-5923
Email: ctsucontact@westat.com

Kimberly A. McGregor
Principal Investigator

Newberg

Providence Newberg Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Oregon City

Providence Willamette Falls Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Portland

Kaiser Permanente

Nagendra Ranganatha Tirumali
Ph: 503-335-2400

Nagendra Ranganatha Tirumali
Principal Investigator

Legacy Good Samaritan Hospital and Medical Center

Regan Mon Look
Ph: 503-280-1223

Regan Mon Look
Principal Investigator

Providence Portland Medical Center

Keith S. Lanier
Ph: 503-215-6412

Keith S. Lanier
Principal Investigator

Pennsylvania
Abington

Abington Memorial Hospital

Willard G. Andrews
Ph: 215-481-2402

Willard G. Andrews
Principal Investigator

Allentown

Lehigh Valley Hospital-Cedar Crest

Suresh G. Nair
Ph: 610-402-2273

Suresh G. Nair
Principal Investigator

Bethlehem

Lehigh Valley Hospital - Muhlenberg

Suresh G. Nair
Ph: 610-402-2273

Suresh G. Nair
Principal Investigator

Danville

Geisinger Medical Center

Joseph Joe Lukose Vadakara
Ph: 570-271-6195
Email: jvadakara@geisinger.edu

Joseph Joe Lukose Vadakara
Principal Investigator

Gettysburg

Adams Cancer Center

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

Langhorne

Saint Mary Medical and Regional Cancer Center

Robert E. Reilly
Ph: 215-750-6514
Email: hogpc@aol.com

Robert E. Reilly
Principal Investigator

Natrona Heights

Allegheny Valley Hospital

Shifeng Stefan Mao
Ph: 877-284-2000

Shifeng Stefan Mao
Principal Investigator

Pittsburgh

Allegheny General Hospital

Shifeng Stefan Mao
Ph: 877-284-2000

Shifeng Stefan Mao
Principal Investigator

University of Pittsburgh Cancer Institute (UPCI)

Leonard Joseph Appleman
Ph: 412-647-8073

Leonard Joseph Appleman
Principal Investigator

York

WellSpan Health-York Hospital

Amir Tabatabai
Ph: 877-441-7957

Amir Tabatabai
Principal Investigator

PR
San Juan

Fundacion De Investigacion de Diego

Deana Hallman Navarro
Ph: 787-765-2363

Deana Hallman Navarro
Principal Investigator

San Juan City Hospital

Luis Baez-Diaz
Ph: 787-758-7348
Email: baez.luis@sanjuanccop.org

Luis Baez-Diaz
Principal Investigator

Rhode Island
Providence

Roger Williams Medical Center

Emily Baiyee
Ph: 401-456-2268
Email: rdavies@rwmc.org

Emily Baiyee
Principal Investigator

South Carolina
Charleston

Bon Secours Saint Francis Hospital

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Charleston Hematology Oncology Associates PA-St. Francis

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Charleston Hematology Oncology Associates-Roper

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Lowcountry Hematology Oncology PA-North Charleston

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Lowcountry Hematology Oncology PA-West Ashley

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Roper Hospital

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Easley

Greenville Health System Cancer Institute-Easley

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

Greenville

Greenville Health System Cancer Institute-Butternut

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

Greenville Health System Cancer Institute-Eastside

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

Greenville Health System Cancer Institute-Faris

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

Saint Francis Cancer Center

Robert D. Siegel
Ph: 864-603-6140
Email: robert_siegel@bshsi.org

Robert D. Siegel
Principal Investigator

Saint Francis Hospital

Robert D. Siegel
Ph: 864-255-1713

Robert D. Siegel
Principal Investigator

Greer

Greenville Health System Cancer Institute-Greer

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

Mount Pleasant

Lowcountry Hematology Oncology PA-Mount Pleasant

Steven Alan Akman
Ph: 843-720-8386
Email: elizabeth.strojny@roperstfrancis.com

Steven Alan Akman
Principal Investigator

Seneca

Greenville Health System Cancer Institute-Seneca

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

Spartanburg

Greenville Health System Cancer Institute-Spartanburg

Jeffrey K. Giguere
Ph: 864-241-6251

Jeffrey K. Giguere
Principal Investigator

South Dakota
Aberdeen

Avera Cancer Institute-Aberdeen

Amy K. Krie
Ph: 605-322-6901
Email: oncregulatory@avera.org

Amy K. Krie
Principal Investigator

Rapid City

Rapid City Regional Hospital

Joshua Cole Lukenbill
Ph: 605-716-3982
Email: research@rcrh.org

Joshua Cole Lukenbill
Principal Investigator

Sioux Falls

Avera Cancer Institute

Amy K. Krie
Ph: 605-322-6901
Email: oncregulatory@avera.org

Amy K. Krie
Principal Investigator

Sanford Cancer Center-Oncology Clinic

Preston D. Steen
Ph: 701-234-6161

Preston D. Steen
Principal Investigator

Tennessee
Germantown

The West Clinic - Wolf River

Bradley G. Somer
Ph: 901-685-2969
Email: bsomer@westclinic.com

Bradley G. Somer
Principal Investigator

Memphis

University of Tennessee Health Science Center

Bradley G. Somer
Ph: 901-448-3303

Bradley G. Somer
Principal Investigator

Texas
Dallas

Parkland Memorial Hospital

Kevin Dale Courtney
Ph: 214-648-1955
Email: kevin.courtney@utsouthwestern.edu

Kevin Dale Courtney
Principal Investigator

UT Southwestern/Simmons Cancer Center-Dallas

Kevin Dale Courtney
Ph: 214-648-7097

Kevin Dale Courtney
Principal Investigator

Fort Worth

UT Southwestern/Simmons Cancer Center-Fort Worth

Kevin Dale Courtney
Ph: 214-648-1955
Email: kevin.courtney@utsouthwestern.edu

Kevin Dale Courtney
Principal Investigator

Houston

Baylor College of Medicine

Aihua Edward Yen
Ph: 713-798-1354
Email: burton@bcm.edu

Aihua Edward Yen
Principal Investigator

Ben Taub General Hospital

Aihua Edward Yen
Ph: 713-798-1354
Email: burton@bcm.edu

Aihua Edward Yen
Principal Investigator

San Antonio

University of Texas Health Science Center at San Antonio

Devalingam Mahalingam
Ph: 210-450-1686
Email: mahalingam@uthscsa.edu

Devalingam Mahalingam
Principal Investigator

Vermont
Burlington

University of Vermont College of Medicine

Steven Ades
Ph: 802-656-4101

Steven Ades
Principal Investigator

White River Junction

White River Junction Veteran Administration Medical Center

Alexander David Fuld
Ph: 802-296-6476
Email: alexander.fuld@va.gov

Alexander David Fuld
Principal Investigator

Virginia
Charlottesville

University of Virginia Cancer Center

Robert Dreicer
Ph: 434-243-6322
Email: JME3D@hscmail.mcc.virginia.edu

Robert Dreicer
Principal Investigator

Hampton

Virginia Oncology Associates-Hampton

Paul R. Conkling
Ph: 757-873-9400
Email: Paul.conkling@usoncology.com

Paul R. Conkling
Principal Investigator

Lynchburg

Lynchburg Hematology-Oncology Clinic

Hetal R. Vachhani
Ph: 804-628-1939

Hetal R. Vachhani
Principal Investigator

Martinsville

Memorial Hospital Of Martinsville

Sreedhar Katragadda
Ph: 276-666-7827

Sreedhar Katragadda
Principal Investigator

Mechanicsville

Bon Secours Memorial Regional Medical Center

William Johnson Irvin
Ph: 804-594-3131
Email: william_irvin@bshsi.org

William Johnson Irvin
Principal Investigator

Midlothian

Bon Secours Saint Francis Medical Center

William Johnson Irvin
Ph: 804-594-4900

William Johnson Irvin
Principal Investigator

Richmond

Virginia Cancer Institute

Hetal R. Vachhani
Ph: 804-628-1939

Hetal R. Vachhani
Principal Investigator

Virginia Commonwealth University/Massey Cancer Center

Hetal R. Vachhani
Ph: 804-628-1939

Hetal R. Vachhani
Principal Investigator

Winchester

Shenandoah Oncology Associates PC

Hetal R. Vachhani
Ph: 804-628-1939

Hetal R. Vachhani
Principal Investigator

Washington
Issaquah

Swedish Cancer Institute-Issaquah

Keith S. Lanier
Ph: 503-216-6324
Email: keith.lanier@providence.org

Keith S. Lanier
Principal Investigator

Poulsbo

Harrison HealthPartners Hematology and Oncology-Poulsbo

Mehmet Sitki Copur
Ph: 800-998-2119

Mehmet Sitki Copur
Principal Investigator

Seattle

Minor and James Medical PLLC

Keith S. Lanier
Ph: 503-216-6324
Email: keith.lanier@providence.org

Keith S. Lanier
Principal Investigator

Swedish Medical Center-First Hill

Keith S. Lanier
Ph: 503-216-6324
Email: keith.lanier@providence.org

Keith S. Lanier
Principal Investigator

West Virginia
Charleston

West Virginia University Charleston

Steven James Jubelirer
Ph: 304-344-3457

Steven James Jubelirer
Principal Investigator

Wisconsin
Antigo

Langlade Hospital and Cancer Center

Christopher Gary Peterson
Ph: 715-847-2409
Email: christopher.peterson@aspirus.org

Christopher Gary Peterson
Principal Investigator

Burlington

Aurora Cancer Care-Burlington

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Eau Claire

Marshfield Clinic Cancer Center at Sacred Heart

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Sacred Heart Hospital

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Elkhorn

Aurora Cancer Care-Southern Lakes

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Fond Du Lac

Saint Agnes Hospital/Agnesian Cancer Center

Michael W. Jones
Ph: 800-494-2927

Michael W. Jones
Principal Investigator

Grafton

Aurora Cancer Care-Grafton

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Green Bay

Aurora BayCare Medical Center

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Green Bay Oncology at Saint Vincent Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Green Bay Oncology Limited at Saint Mary's Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Saint Mary's Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Saint Vincent Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Janesville

Mercy Health System

Emily Gray Robinson
Ph: 608-756-6836
Email: erobinson@mhsjvl.org

Emily Gray Robinson
Principal Investigator

Kenosha

Aurora Cancer Care-Kenosha South

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

La Crosse

Gundersen Lutheran Medical Center

Michael O Ojelabi
Ph: 608-775-2385
Email: cancerctr@gundersenhealth.org

Michael O Ojelabi
Principal Investigator

Madison

William S Middleton VA Medical Center

Justine Yang-Bruce
Ph: 608-265-0614
Email: jybruce@medicine.wisc.edu

Justine Yang-Bruce
Principal Investigator

Manitowoc

Holy Family Memorial Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Marinette

Vince Lombardi Cancer Clinic-Marinette

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Marshfield

Marshfield Clinic

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Saint Joseph's Hospital

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Menomonee Falls

Aurora Advanced Healthcare Inc-Menomonee Falls

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Milwaukee

Aurora Cancer Care-Milwaukee

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Aurora Saint Luke's Medical Center

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Aurora Sinai Medical Center

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Froedtert and the Medical College of Wisconsin

Kathryn A. Bylow
Ph: 414-805-4380

Kathryn A. Bylow
Principal Investigator

Zablocki Veterans Administration Medical Center

Elizabeth M. Gore
Ph: 414-805-4380

Elizabeth M. Gore
Principal Investigator

Minocqua

Marshfield Clinic-Minocqua Center

Seth Olusegun Fagbemi
Ph: 715-221-8940
Email: fagbemi.seth@marshfieldclinic.org

Seth Olusegun Fagbemi
Principal Investigator

Mukwonago

D N Greenwald Center

Timothy Robert Wassenaar
Ph: 262-928-5539
Email: Chanda.miller@phci.org

Timothy Robert Wassenaar
Principal Investigator

Oconomowoc

Oconomowoc Memorial Hospital-ProHealth Care Inc

Timothy Robert Wassenaar
Ph: 262-928-5539
Email: Chanda.miller@phci.org

Timothy Robert Wassenaar
Principal Investigator

Oconto Falls

Green Bay Oncology - Oconto Falls

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Oshkosh

Vince Lombardi Cancer Clinic - Oshkosh

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Racine

Aurora Cancer Care-Racine

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Wheaton Franciscan Cancer Care - All Saints

Young M. (Mark) Choi
Ph: 262-687-5098
Email: young.choi@wfhc.org

Young M. (Mark) Choi
Principal Investigator

Rice Lake

Marshfield Clinic-Rice Lake Center

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Sheboygan

Saint Nicholas Hospital

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Vince Lombardi Cancer Clinic-Sheboygan

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Stevens Point

Marshfield Clinic Cancer Care at Saint Michael's Hospital

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Saint Michael's Hospital

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Sturgeon Bay

Green Bay Oncology - Sturgeon Bay

Anthony John Jaslowski
Ph: 800-432-6049

Anthony John Jaslowski
Principal Investigator

Summit

Aurora Medical Center in Summit

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Two Rivers

Vince Lombardi Cancer Clinic

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Waukesha

Aurora Cancer Care-Waukesha

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Waukesha Memorial Hospital

Timothy Robert Wassenaar
Ph: 262-928-5539
Email: Chanda.miller@phci.org

Timothy Robert Wassenaar
Principal Investigator

Wausau

Aspirus Regional Cancer Center

Christopher Gary Peterson
Ph: 715-847-2409
Email: christopher.peterson@aspirus.org

Christopher Gary Peterson
Principal Investigator

Wauwatosa

Aurora Cancer Care-Milwaukee West

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

West Allis

Aurora West Allis Medical Center

Dhimant R. Patel
Ph: 800-252-2990

Dhimant R. Patel
Principal Investigator

Weston

Diagnostic and Treatment Center

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Marshfield Clinic - Weston Center

Seth Olusegun Fagbemi
Ph: 715-389-4457

Seth Olusegun Fagbemi
Principal Investigator

Wisconsin Rapids

Aspirus UW Cancer Center

Christopher Gary Peterson
Ph: 715-847-2409
Email: christopher.peterson@aspirus.org

Christopher Gary Peterson
Principal Investigator

Canada

Alberta
Edmonton

Cross Cancer Institute

Scott Arthur North
Ph: 780-432-8500

Scott Arthur North
Principal Investigator

British Columbia
Vancouver

BCCA-Vancouver Cancer Centre

Kim Nguyen Chi
Ph: 888-939-3333

Kim Nguyen Chi
Principal Investigator

New Brunswick
Moncton

The Moncton Hospital

Mahmoud Abdelsalam
Ph: 506-857-5241
Email: dr.mahmoud.abdelsalam@horizonnb.ca

Mahmoud Abdelsalam
Principal Investigator

The Vitalite Health Network - Dr Leon Richard Oncology Centre

Ali Benjelloun
Ph: 506-862-4005

Ali Benjelloun
Principal Investigator

Saint John

Atlantic Health Sciences Corporation-Saint John Regional Hospital

Samantha Lee Gray
Ph: 506-648-6890

Samantha Lee Gray
Principal Investigator

Newfoundland and Labrador
St. John's

Doctor H. Bliss Murphy Cancer Centre

Sohaib Al-Asaaed
Ph: 709-777-7589

Sohaib Al-Asaaed
Principal Investigator

Ontario
Cambridge

Cambridge Memorial Hospital

Edmond Emilien Chouinard
Ph: 519-740-7722
Email: echouinard@cmh.org

Edmond Emilien Chouinard
Principal Investigator

Kitchener

Grand River Regional Cancer Centre at Grand River Hospital

Stacey Hubay
Ph: 519-749-4300ext2307

Stacey Hubay
Principal Investigator

Link to the current ClinicalTrials.gov record.
NLM Identifier NCT01949337

Note: Information about participating sites on pharmaceutical industry trials may be incomplete. Please visit the ClinicalTrials.gov record via the link above for more information about participating sites.