Ibrutinib and Rituximab Compared With Fludarabine Phosphate, Cyclophosphamide, and Rituximab in Treating Patients With Untreated Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

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Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIIBiomarker/Laboratory analysis, TreatmentActive18 to 70NCINCI-2014-00118
ECOG-E1912, E1912, U10CA180820, U10CA021115, NCT02048813

Trial Description

Summary

This randomized phase III trial studies ibrutinib and rituximab to see how well they work compared to fludarabine phosphate, cyclophosphamide, and rituximab in treating patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. It is not yet known whether fludarabine phosphate, cyclophosphamide, and rituximab are more effective than ibrutinib and rituximab in treating patients with untreated chronic lymphocytic leukemia or small lymphocytic lymphoma.

Further Study Information

PRIMARY OBJECTIVES:

I. To evaluate the ability of Ibrutinib-based induction therapy to prolong progression free survival (PFS) compared to standard fludarabine phosphate, cyclophosphamide, and rituximab (FCR) chemoimmunotherapy for younger patients with chronic lymphocytic leukemia (CLL).

SECONDARY OBJECTIVES:

I. Evaluate overall survival (OS) of patients based on treatment arm. II. Monitor and assess toxicity of treatment with Ibrutinib-based induction relative to standard FCR chemotherapy.

III. To compare quality of life (QOL) in CLL patients during the first 6 months of treatment among patients receiving Ibrutinib-based induction therapy relative to standard FCR chemoimmunotherapy.

IV. To compare QOL over the long-term in CLL patients receiving continuous therapy using Ibrutinib to that of CLL patients who completed FCR therapy.

V. Determine the effect of pretreatment clinical and biological characteristics (e.g. disease stage, immunoglobulin heavy chain variable region gene [IGHV] mutation status, fluorescent in situ hybridization [FISH]) on clinical outcomes (e.g. complete response, PFS) of the different arms.

VI. Determine if the minimal residual disease (MRD) status as assessed by flow cytometry at different time points during and after treatment is an effective surrogate marker for prolonged PFS and overall survival.

VII. Compare the genetic abnormalities and dynamics of intra-clonal architecture of CLL patients before and after treatment with chemoimmunotherapy (CIT) and non-CIT approaches and explore relationships with treatment resistance.

VIII. Explore the effects of FCR and Ibrutinib-based therapy on T-cell immune function.

IX. Conduct confirmatory validation genotyping of single nucleotide polymorphisms (SNPs) associated with the efficacy and toxicity of fludarabine-based therapy as in a prior Eastern Cooperative Oncology Group (ECOG) genome-wide association study (GWAS) analysis in the E2997 trial.

X. Evaluate the ability of prognostic model that incorporates clinical and biologic characters to predict a response to therapy and clinical outcome (PFS, OS).

XI. Evaluate signaling networks downstream of the B-cell receptor in patients receiving Ibrutinib-based therapy.

XII. Collect relapse samples to study mechanisms of resistance to both FCR and Ibrutinib-based therapy.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM A: Patients receive ibrutinib orally (PO) once daily (QD) on days 1-28. Beginning course 2, patients also receive rituximab intravenously (IV) over 4 hours on day 1 (days 1 and 2 of course 2 only). Treatment repeats every 28 days for 7 courses. In the absence of disease progression, patients may continue ibrutinib PO QD.

ARM B: Patients receive rituximab as seen in Arm A and fludarabine phosphate IV over 30 minutes and cyclophosphamide IV over 30 minutes on days 1-3. Treatment repeats every 28 days for 6 courses.

After completion of study treatment, patients are followed up for 10 years.

Eligibility Criteria

Inclusion Criteria:

  • Diagnosis of CLL according to the National Cancer Institute (NCI)/Internal Workshop on Chronic Lymphocytic Leukemia (IWCLL) criteria or small lymphocytic lymphoma (SLL) according to the World Health Organization (WHO) criteria; this includes previous documentation of:
  • Biopsy-proven small lymphocytic lymphoma OR
  • Diagnosis of CLL according to the NCI/IWCLL criteria as evidenced by all of the following:
  • Peripheral blood lymphocyte count of greater than 5 x10^9/L
  • Immunophenotype consistent with CLL defined as:
  • The predominant population of lymphocytes share both B-cell antigens (cluster of differentiation [CD]19, CD20 [typically dim expression], or CD23) as well as CD5 in the absence of other pan-T-cell markers (CD3, CD2, etc)
  • Clonality as evidenced by kappa or lambda light chain restriction (typically dim immunoglobulin expression)
  • Negative FISH analysis for t(11;14)(immunoglobulin heavy locus [IgH]/cyclin D1 [CCND1]) on peripheral blood or tissue biopsy (e.g. marrow aspirate) or negative immunohistochemical stains for cyclin D1 staining on involved tissue biopsy (e.g. marrow aspirate or lymph node biopsy)
  • No prior chemotherapy or monoclonal anti-body therapy for treatment of CLL or SLL
  • Has met at least one of the following indications for treatment:
  • Evidence of progressive marrow failure as manifested by the development of worsening anemia (hemoglobin [Hg] < 11 g/dl) and/or thrombocytopenia (platelets < 100 x 10^9/L)
  • Symptomatic or progressive lymphadenopathy, splenomegaly, or hepatomegaly
  • One or more of the following disease-related symptoms:
  • Weight loss >= 10% within the previous 6 months
  • Grade 2 or 3 fatigue attributed to CLL
  • Fevers > 100.5 Fahrenheit (F) for 2 weeks without evidence of infection
  • Clinically significant night sweats without evidence of infection
  • Progressive lymphocytosis (not due to the effects of corticosteroids) with an increase of > 50% over a two-month period or an anticipated doubling time of less than six months
  • ECOG performance status between 0-2
  • Life expectancy of >= 12 months
  • Ability to tolerate FCR based therapy
  • No deletion of 17p13 on cytogenetic analysis by FISH
  • Glomerular filtration rate (GFR) > 40 mL/minute as calculated by the Cockcroft-Gault formula
  • Total bilirubin =< 2.5 x upper limit of normal (ULN) unless due to Gilbert's disease; for those with a total bilirubin > 2.5 x ULN, a direct bilirubin should be performed and must be < 1.5 mg/dL for Gilbert's to be diagnosed; if value is higher due to hepatic involvement by CLL, patient is eligible
  • Serum glutamic oxaloacetic transaminase (SGOT) =< 2.5 x ULN; if value is higher due to hepatic involvement by CLL, patient is eligible
  • No active hemolytic anemia requiring immunosuppressive therapy or other pharmacologic treatment; patients who have a positive Coombs test but no evidence of hemolysis are NOT excluded from participation
  • No current use of corticosteroids; EXCEPTION: low doses of steroids (< 10 mg of prednisone or equivalent dose of other steroid) used for treatment of non-hematologic medical condition (e.g. chronic adrenal insufficiency) is permitted
  • No previous use of corticosteroids for autoimmune complications that have developed since the initial diagnosis of CLL; prior use of corticosteroids for reasons other than treatment of autoimmune complications is allowed
  • No other active primary malignancy (other than non-melanomatous skin cancer or carcinoma in situ of the cervix) requiring treatment or limiting expected survival to =< 2 years; NOTE: if there is a history of prior malignancy, they must not be receiving other specific treatment (other than hormonal therapy for their cancer)
  • Able to adhere to the study visit schedule and other protocol requirements
  • No major surgery within the last 28 days prior to registration or minor surgery within the last 5 days
  • No radiation therapy =< 4 weeks prior to registration
  • Patients with human immunodeficiency virus (HIV) infection may be eligible provided they meet the following criteria:
  • CD4-positive cell count >= lower limit of institutional normal
  • HIV viral load < 10,000 copies HIV ribonucleic acid (RNA)/mL (if not on anti-HIV therapy) OR < 50 copies HIV RNA/mL (if on anti-HIV therapy)
  • No evidence of hepatitis B or C infection
  • No evidence of resistant strains of HIV
  • No history of acquired immune deficiency syndrome (AIDS)-defining condition
  • Patients must not have any of the following conditions:
  • New York Heart Association class III or IV heart disease
  • Recent myocardial infarction (=< 3 months)
  • Uncontrolled infection
  • Cerebral vascular accident or intracranial bleed within the last 6 months
  • Infection with known chronic, active hepatitis C
  • Positive serology for hepatitis B defined as a positive test for hepatitis B surface antigen (HBsAg); in addition, if negative for HBsAg but hepatitis B core antibody (HBcAb) positive (regardless of HBsAb status), a hepatitis B deoxyribonucleic acid (DNA) test will be performed and, if positive the subject will be ineligible
  • Patients are not eligible if they require chronic use of strong or moderate cytochrome P450, family 3, subfamily A, polypeptide 4 (CYP3A4)/5 inhibitors or inducers at the time of registration
  • Patients may not be on any other investigational agents
  • Patients may not have received warfarin or another vitamin K antagonist in the preceding 30 days
  • Women must not be pregnant or breast-feeding; all females of childbearing potential must have a blood test or urine study within 2 weeks prior to registration to rule out pregnancy; a female of childbearing potential is any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria:
  • Has not undergone a hysterectomy or bilateral oophorectomy; or
  • Has not been naturally postmenopausal for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)
  • Women of childbearing potential and sexually active males must be strongly advised to use an accepted and effective method of contraception or to abstain from sexual intercourse for the duration of their participation in the study

Trial Contact Information

Trial Lead Organizations/Sponsors

National Cancer Institute

    Tait Shanafelt, Principal Investigator

    Trial Sites

    U.S.A.

    Alabama
    Birmingham

    UAB Comprehensive Cancer Center

    Harry Paul Erba
    Ph: 205-934-0309

    Alaska
    Anchorage

    Alaska Breast Care and Surgery LLC

    Keith S. Lanier
    Ph: 503-215-6412

    Alaska Women's Cancer Care

    Keith S. Lanier
    Ph: 503-215-6412

    Anchorage Oncology Centre

    Keith S. Lanier
    Ph: 503-215-6412

    Katmai Oncology Group

    Keith S. Lanier
    Ph: 503-215-6412

    Providence Cancer Center

    Keith S. Lanier
    Ph: 503-215-6412

    Fairbanks

    Fairbanks Cancer Treatment Center at Fairbanks Memorial Hospital

    John A Keech
    Ph: 907-458-5380

    Arizona
    Scottsdale

    Mayo Clinic Scottsdale

    Tait D. Shanafelt
    Ph: 507-538-7623

    Arkansas
    Jonesboro

    NEA Medical Clinic - East Matthews

    Carroll Dean Scroggin
    Ph: 870-972-7235

    Little Rock

    Arkansas Cancer Research Center at University of Arkansas for Medical Sciences

    Rangaswamy Govindarajan
    Ph: 501-686-8274

    California
    Anaheim

    Kaiser Permanente Medical Center - Anaheim/Orange County

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Antioch

    Kaiser Permanente - Deer Valley

    Tatjana Kolevska
    Ph: 626-564-3455

    Auburn

    Auburn Radiation Oncology

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Sutter Auburn Faith Hospital

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Baldwin Park

    Kaiser Permanente Medical Center - Baldwin Park

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Bellflower

    Kaiser Permanente Medical Center - Bellflower

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Berkeley

    Alta Bates Summit Comprehensive Cancer Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Burbank

    Roy and Patricia Disney Family Cancer Center at Providence Saint Joseph Medical Center

    Keith S. Lanier
    Ph: 503-215-6412

    Burlingame

    Peninsula Medical Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Cameron Park

    Radiation Oncology Centers - Cameron Park

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Campbell

    Southbay Oncology / Hematology Medical Group

    Steven E Coutre
    Ph: 650-498-7061
    Email: ccto-office@stanford.edu

    Davis

    Sutter Davis Hospital

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Fontana

    Kaiser Permanente Medical Center - Fontana

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Fremont

    Kaiser Permanente - Fremont

    Tatjana Kolevska
    Ph: 626-564-3455

    Fresno

    Kaiser Permanente Fresno Medical Center

    Tatjana Kolevska
    Ph: 626-564-3455

    Greenbrae

    Marin Cancer Institute at Marin General Hospital

    Peter D. Eisenberg
    Ph: 415-925-5000
    Email: info@marinspecialtycare.com

    Peter D. Eisenberg
    Ph: 415-925-5000
    Email: info@marinspecialtycare.com

    Harbor City

    Kaiser Permanente Medical Center - Harbor City

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Irvine

    Kaiser Permanente - Irvine

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Los Angeles

    Kaiser Foundation Hospital - West Los Angeles

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Kaiser Permanente Medical Center - Los Angeles

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Modesto

    Kaiser Permanente-Modesto

    Tatjana Kolevska
    Ph: 626-564-3455

    Memorial Medical Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Mountain View

    Palo Alto Medical Foundation

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Novato

    Sutter Health Western Division Cancer Research Group

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Oakland

    Kaiser Permanente-Oakland

    Tatjana Kolevska
    Ph: 626-564-3455

    Orange

    Chao Family Comprehensive Cancer Center at University of California Irvine Medical Center

    Deepa Jeyakumar
    Ph: 877-827-8839
    Email: ucstudy@uci.edu

    Palo Alto

    Palo Alto Medical Foundation - Palo Alto

    Peter P. Yu
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Stanford Cancer Center

    Steven E Coutre
    Ph: 650-498-7061
    Email: ccto-office@stanford.edu

    Panorama City

    Kaiser Permanente Medical Group

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Paradise

    Feather River Hospital Cancer Center

    Sam Mazj
    Ph: 530-876-7995
    Email: haleew@ah.org

    Redwood City

    Kaiser Permanente Medical Center - Redwood City

    Tatjana Kolevska
    Ph: 626-564-3455

    Richmond

    Kaiser Permanente Medical Center - Richmond

    Tatjana Kolevska
    Ph: 626-564-3455

    Riverside

    Kaiser Permanente Medical Center - Riverside

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Roseville

    Kaiser Permanente Medical Center - Roseville

    Tatjana Kolevska
    Ph: 626-564-3455

    Radiation Oncology Center - Roseville

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Sutter Cancer Center at Roseville Medical Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Sacramento

    Kaiser Permanente Medical Center - Sacramento

    Tatjana Kolevska
    Ph: 626-564-3455

    South Sacramento Kaiser-Permanente Medical Center

    Tatjana Kolevska
    Ph: 626-564-3455

    Sutter Cancer Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    San Diego

    Kaiser Permanente Medical Center - Kaiser Foundation Hospital - San Diego

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Kaiser Permanente Medical Office -Vandever Medical Office

    Jonathan A. Polikoff
    Ph: 626-564-3455

    San Francisco

    California Pacific Medical Center - California Campus

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Kaiser Permanente Medical Center - San Francisco Geary Campus

    Tatjana Kolevska
    Ph: 626-564-3455

    San Jose

    Kaiser Permanente Medical Center - Santa Teresa

    Tatjana Kolevska
    Ph: 626-564-3455

    San Leandro

    Kaiser Permanente Medical Center - Hayward

    Tatjana Kolevska
    Ph: 626-564-3455

    San Marcos

    Kaiser Permanente Health Care

    Jonathan A. Polikoff
    Ph: 626-564-3455

    San Rafael

    Kaiser Foundation Hospital - San Rafael

    Tatjana Kolevska
    Ph: 626-564-3455

    Santa Clara

    Kaiser Permanente Medical Center - Santa Clara Homestead Campus

    Tatjana Kolevska
    Ph: 626-564-3455

    Santa Cruz

    Palo Alto Medical Foundation-Santa Cruz

    Peter P. Yu
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Santa Rosa

    Kaiser Permanente Medical Center - Santa Rosa

    Tatjana Kolevska
    Ph: 626-564-3455

    Sutter Pacific Medical Foundation

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    South San Francisco

    Kaiser Permanente Medical Center - South San Francisco

    Tatjana Kolevska
    Ph: 626-564-3455

    Stockton

    Kaiser Permanente Medical Facility - Stockton

    Tatjana Kolevska
    Ph: 626-564-3455

    Sunnyvale

    Palo Atlo Medical Foundation-Sunnyvale

    Peter P. Yu
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Vacaville

    Kaiser Permanente Medical Center - Vacaville

    Tatjana Kolevska
    Ph: 626-564-3455

    Solano Radiation Oncology Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Vallejo

    Kaiser Permanente Medical Center - Vallejo

    Tatjana Kolevska
    Ph: 626-564-3455

    Sutter Solano Medical Center

    David A Shiba
    Ph: 415-209-2686
    Email: bernicl@sutterhealth.org

    Walnut Creek

    Kaiser Permanente Medical Center - Walnut Creek

    Tatjana Kolevska
    Ph: 626-564-3455

    Woodland Hills

    Kaiser Permanente Medical Cener - Woodland Hills

    Jonathan A. Polikoff
    Ph: 626-564-3455

    Colorado
    Aurora

    Medical Center of Aurora - South Campus

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers - Aurora

    Keren Sturtz
    Ph: 888-785-6789

    Boulder

    Boulder Community Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers-Boulder

    Keren Sturtz
    Ph: 888-785-6789

    Colorado Springs

    Penrose Cancer Center at Penrose Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers at the Pavilion

    Keren Sturtz
    Ph: 888-785-6789

    Denver

    CCOP - Colorado Cancer Research Program

    Keren Sturtz
    Ph: 888-785-6789

    Colorado Blood Cancer Institute

    Keren Sturtz
    Ph: 888-785-6789

    Kaiser Permanente of Colorado

    Alexander Menter
    Ph: 303-614-1300

    Porter Adventist Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Presbyterian - St. Luke's Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers - Denver Midtown

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers-Rose

    Keren Sturtz
    Ph: 888-785-6789

    Rose Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    St. Joseph Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Durango

    Mercy Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Southwest Oncology, PC

    Keren Sturtz
    Ph: 888-785-6789

    Englewood

    Comprehensive Cancer Care and Research Institute of Colorado LLC

    Keren Sturtz
    Ph: 888-785-6789

    Swedish Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Golden

    Mountain Blue Cancer Care Center

    Keren Sturtz
    Ph: 888-785-6789

    Greeley

    North Colorado Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Greenwood Village

    Breast Cancer Care Consultants

    Keren Sturtz
    Ph: 888-785-6789

    Lafayette

    Kaiser Permanente - Lafayette

    Alexander Menter
    Ph: 303-614-1300

    Lakewood

    Rocky Mountain Cancer Centers-Lakewood

    Keren Sturtz
    Ph: 888-785-6789

    St. Anthony Central Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Littleton

    Littleton Adventist Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers - Littleton

    Keren Sturtz
    Ph: 888-785-6789

    Lone Tree

    Kaiser Permanente-Lone Tree

    Alexander Menter
    Ph: 303-614-1300

    Rocky Mountain Cancer Centers - Lone Tree

    Keren Sturtz
    Ph: 888-785-6789

    Sky Ridge Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Longmont

    Hope Cancer Care Center at Longmont United Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers - Longmont

    Keren Sturtz
    Ph: 888-785-6789

    Loveland

    McKee Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Parker

    Parker Adventist Hospital

    Keren Sturtz
    Ph: 888-785-6789

    Rocky Mountain Cancer Centers - Parker

    Keren Sturtz
    Ph: 888-785-6789

    Pueblo

    Rocky Mountain Cancer Centers - Pueblo

    Keren Sturtz
    Ph: 888-785-6789

    St. Mary - Corwin Regional Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Thornton

    Rocky Mountain Cancer Centers - Thornton

    Keren Sturtz
    Ph: 888-785-6789

    Wheat Ridge

    Exempla Lutheran Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Connecticut
    Derby

    Griffin Hospital

    Iris Isufi
    Ph: 203-785-5702

    Hartford

    Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Middletown

    Middlesex Hospital Cancer Center

    Susanna Hong
    Ph: 860-358-2058

    New Haven

    Smilow Cancer Hospital at Yale-New Haven

    Iris Isufi
    Ph: 203-785-5702

    Yale Cancer Center

    Iris Isufi
    Ph: 203-785-5702

    North Haven

    Yale-New Haven Hospital North Haven Medical Center

    Iris Isufi
    Ph: 203-785-5702

    Orange

    Smilow Cancer Hospital-Orange Care Center

    Iris Isufi
    Ph: 203-785-5702

    Torrington

    Connecticut Oncology & Hematology - Torrington

    Iris Isufi
    Ph: 203-785-5702

    Waterbury

    Harold Leever Regional Cancer Center

    Iris Isufi
    Ph: 203-785-5702

    Delaware
    Lewes

    Tunnell Cancer Center at Beebe Medical Center

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Newark

    Christiana Gynecologic Oncology, LLC

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Delaware Clinical and Laboratory Physicians

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Helen F. Graham Cancer Center at Christiana Hospital

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Medical Oncology Hematology Consultants, PA at Helen F. Graham Cancer Center

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Regional Hematology/Oncology, PA - Newark

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Rehoboth Beach

    Beebe Health Campus

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Seaford

    Nanticoke Memorial Hospital

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Wilmington

    Christiana Care Health System-Wilmington Hospital

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Florida
    Lakeland

    Lakeland Regional Cancer Center at Lakeland Regional Medical Center

    Sushma S Nakka
    Ph: 863-904-1900

    Georgia
    Albany

    Phoebe Cancer Center at Phoebe Putney Memorial Hospital

    Jose M. Tongol
    Ph: 229-312-2251

    Atlanta

    Winship Cancer Institute of Emory University

    Leonard Thompson Heffner
    Ph: 404-778-1868

    Macon

    Medical Center of Central Georgia

    Frederick M. Schnell
    Ph: 404-501-3279

    Savannah

    Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler

    Grant C Lewis
    Ph: 912-350-8568

    Hawaii
    Honolulu

    Kaiser Permanente - Moanalua Medical Center and Clinic

    Tatjana Kolevska
    Ph: 626-564-3455

    Idaho
    Boise

    Saint Alphonsus Cancer Care Center at Saint Alphonsus Regional Medical Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Illinois
    Aurora

    Rush-Copley Cancer Care Center

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Bloomington

    Illinois CancerCare - Bloomington

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    St. Joseph Medical Center

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Canton

    Illinois CancerCare - Canton

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Carbondale

    Memorial Hospital of Carbondale

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Carthage

    Illinois CancerCare - Carthage

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Centralia

    Centralia Oncology Clinic

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Chicago

    Robert H. Lurie Comprehensive Cancer Center at Northwestern University

    Shuo Ma
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    University of Chicago Cancer Research Center

    Michael J Thirman
    Ph: 773-834-7424

    Danville

    Carle on Vermilion

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Decatur

    Cancer Care Center of Decatur

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Decatur Memorial Hospital Cancer Care Institute

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Effingham

    Carle Physician Group-Effingham

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Crossroads Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Elk Grove Village

    Cancer Institute at Alexian Brothers

    Bruce B. Bank
    Ph: 847-952-7164
    Email: fredianc@alexian.net

    Eureka

    Illinois CancerCare - Eureka

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Evanston

    CCOP - Evanston

    David L. Grinblatt
    Ph: 847-570-2109

    Galesburg

    Galesburg Clinic, PC

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    InterCommunity Cancer Center of Western Illinois

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Medical and Surgical Specialists, LLC

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Glenview

    Glenbrook Hospital

    David L. Grinblatt
    Ph: 847-570-2109

    Highland Park

    Hematology Oncology Associates of Illinois-Highland Park

    Shuo Ma
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Highland Park Hospital

    David L. Grinblatt
    Ph: 847-570-2109

    Joliet

    Joliet Oncology-Hematology Associates, Limited - West

    Kulumani M Sivarajan
    Ph: 815-730-3098
    Email: maureenc@jolietoncology.com

    Kankakee

    Provena St. Mary's Regional Cancer Center - Kankakee

    Shuo Ma
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Kewanee

    Illinois CancerCare - Kewanee Clinic

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Libertyville

    North Shore Oncology and Hematology Associates, Limited - Libertyville

    Shuo Ma
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Macomb

    Illinois CancerCare - Macomb

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Mattoon

    Carle Physician Group-Mattoon/Charleston

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Maywood

    Cardinal Bernardin Cancer Center at Loyola University Medical Center

    Kathleen W Phelan
    Ph: 708-226-4357

    Mount Vernon

    Good Samaritan Regional Health Center

    Jay W Carlson
    Ph: 800-821-7532

    Niles

    Cancer Care and Hematology Specialists of Chicagoland - Niles

    Shuo Ma
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Oak Lawn

    Advocate Christ Medical Center

    Rami Y Haddad
    Ph: 800-323-8622

    Ottawa

    Illinois CancerCare - Ottawa

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Radiation Oncology of Northern Illinois

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Pekin

    Cancer Treatment Center at Pekin Hospital

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Illinois CancerCare - Pekin

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Peoria

    Illinois CancerCare - Peoria

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Methodist Medical Center of Illinois

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    OSF Saint Francis Medical Center Radiation Oncology Service at the Central Illinois Comprehensive CC

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    OSF St. Francis Medical Center

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Peru

    Illinois CancerCare - Princeton

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Valley Cancer Center

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Princeton

    Illinois CancerCare - Princeton

    Nguyet A Le-Lindqwister
    Ph: 800-793-2262

    Rockford

    Advanced Care and Treatment Medical Group, PC

    Harvey Eric Einhorn
    Ph: 779-696-9400
    Email: cancercare@swedishamerican.org

    Skokie

    Hematology Oncology Associates - Skokie

    Shuo Ma
    Ph: 312-695-1301
    Email: cancer@northwestern.edu

    Rush North Shore Medical Center

    David L. Grinblatt
    Ph: 847-570-2109

    Springfield

    Central Illinois Hematology Oncology Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Regional Cancer Center at Memorial Medical Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Simmons Cooper Cancer Institute

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Springfield Clinic - Main Campus

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Swansea

    Cancer Care Specialists of Illinois-Swansea

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Urbana

    Carle Cancer Center at Carle Foundation Hospital

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Warrenville

    Central Dupage Cancer Center

    Robert A. Bayer
    Ph: 630-208-4563
    Email: kevin.tomczyk@delnor.com

    Yorkville

    Rush-Copley Healthcare Center

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Indiana
    Michigan City

    Saint Anthony Memorial Health Centers

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Woodland Cancer Care Center

    Maria T Grosse-Perdekamp
    Ph: 800-446-5532

    Richmond

    Reid Hospital & Health Care Services

    Howard M. Gross
    Ph: 937-775-1350

    Iowa
    Ames

    McFarland Clinic, PC

    Joseph James Merchant
    Ph: 515-239-2621

    William R. Bliss Cancer Center at Mary Greeley Medical Center

    Joseph James Merchant
    Ph: 515-239-2621

    Boone

    McFarland Clinic PC-Boone

    Joseph James Merchant
    Ph: 515-239-2621

    Clive

    Medical Oncology and Hematology Associates-West Des Moines

    Mehmet S. Copur
    Ph: 800-998-2119

    Mercy Cancer Center - West Lakes

    Mehmet S. Copur
    Ph: 800-998-2119

    Council Bluffs

    Alegent Health Mercy Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Des Moines

    Medical Oncology and Hematology Associates at Mercy Cancer Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Mercy Cancer Center at Mercy Medical Center - Des Moines

    Mehmet S. Copur
    Ph: 800-998-2119

    Fort Dodge

    Trinity Regional Medical Center

    Joseph James Merchant
    Ph: 515-239-2621

    Jefferson

    McFarland Clinic PC-Jefferson

    Joseph James Merchant
    Ph: 515-239-2621

    Marshalltown

    McFarland Clinic PC-Marshalltown

    Joseph James Merchant
    Ph: 515-239-2621

    Mason City

    Mercy Cancer Center at Mercy Medical Center - North Iowa

    Arvind Y Vemula
    Ph: 800-433-3883

    Sioux City

    Siouxland Hematology-Oncology Associates, LLP

    Donald Bruce Wender
    Ph: 712-252-0088

    Waterloo

    Covenant Cancer Treatment Center

    Mohammed T. Masri
    Ph: 319-272-2070

    West Des Moines

    Methodist West Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Kansas
    Chanute

    Cancer Center of Kansas, PA - Chanute

    Shaker R. Dakhil
    Ph: 316-262-4467

    Dodge City

    Cancer Center of Kansas, PA - Dodge City

    Shaker R. Dakhil
    Ph: 316-262-4467

    El Dorado

    Cancer Center of Kansas, PA - El Dorado

    Shaker R. Dakhil
    Ph: 316-262-4467

    Fort Scott

    Cancer Center of Kansas - Fort Scott

    Shaker R. Dakhil
    Ph: 316-262-4467

    Independence

    Cancer Center of Kansas-Independence

    Shaker R. Dakhil
    Ph: 316-262-4467

    Kingman

    Cancer Center of Kansas, PA - Kingman

    Shaker R. Dakhil
    Ph: 316-262-4467

    Lawrence

    Lawrence Memorial Hospital

    Shaker R. Dakhil
    Ph: 316-262-4467

    Liberal

    Cancer Center of Kansas, PA - Liberal

    Shaker R. Dakhil
    Ph: 316-262-4467

    Newton

    Cancer Center of Kansas, PA - Newton

    Shaker R. Dakhil
    Ph: 316-262-4467

    Parsons

    Cancer Center of Kansas, PA - Parsons

    Shaker R. Dakhil
    Ph: 316-262-4467

    Pratt

    Cancer Center of Kansas, PA - Pratt

    Shaker R. Dakhil
    Ph: 316-262-4467

    Salina

    Cancer Center of Kansas, PA - Salina

    Shaker R. Dakhil
    Ph: 316-262-4467

    Topeka

    Cotton-O'Neil Cancer Center

    Mehmood H Hashmi
    Ph: 785-270-4963

    Wellington

    Cancer Center of Kansas, PA - Wellington

    Shaker R. Dakhil
    Ph: 316-262-4467

    Wichita

    Associates in Women's Health, PA - North Hillside

    Shaker R. Dakhil
    Ph: 316-262-4467

    Cancer Center of Kansas, PA - Medical Arts Tower

    Shaker R. Dakhil
    Ph: 316-262-4467

    Cancer Center of Kansas, PA - Wichita

    Shaker R. Dakhil
    Ph: 316-262-4467

    Via Christi Cancer Center at Via Christi Regional Medical Center

    Shaker R. Dakhil
    Ph: 316-262-4467

    Winfield

    Cancer Center of Kansas, PA - Winfield

    Shaker R. Dakhil
    Ph: 316-262-4467

    Kentucky
    Bardstown

    Flaget Memorial Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Corbin

    Commonwealth Cancer Center-Corbin

    Mehmet S. Copur
    Ph: 800-998-2119

    Crestview Hills

    Oncology Hematology Care, Incorporated - Crestview Hills

    Howard M. Gross
    Ph: 937-775-1350

    Lexington

    Saint Joseph East

    Mehmet S. Copur
    Ph: 800-998-2119

    United Radiation Oncology - Bob-O-Link Drive Office

    Mehmet S. Copur
    Ph: 800-998-2119

    Louisville

    Jewish Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Jewish Hospital Medical Center Northeast

    Mehmet S. Copur
    Ph: 800-998-2119

    Saints Mary and Elizabeth Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Shepherdsville

    Jewish Hospital Medical Center South

    Mehmet S. Copur
    Ph: 800-998-2119

    Louisiana
    Baton Rouge

    Ochsner Health Center - Bluebonnet

    Robert V. Emmons
    Ph: 888-562-4763

    Kenner

    Ochsner Health Center - Kenner

    Robert V. Emmons
    Ph: 888-562-4763

    New Orleans

    Ochsner Cancer Institute at Ochsner Clinic Foundation

    Robert V. Emmons
    Ph: 888-562-4763

    Maine
    Augusta

    Harold Alfond Center for Cancer Care

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Brewer

    Lafayette Family Cancer Center-EMMC

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Rockport

    Penobscot Bay Medical Center Cancer Care Center

    Thomas Henry Openshaw
    Ph: 207-973-4274

    Massachusetts
    Beverly

    Beverly Hospital

    Angus P. McIntyre
    Ph: 978-283-4000ext559

    Boston

    Eastern Cooperative Oncology Group

    Tait D. Shanafelt
    Ph: 507-284-2358
    Email: shanafelt.tait@mayo.edu

    Tufts Medical Center Cancer Center

    Andreas K Klein
    Ph: 617-636-5000
    Email: ContactUsCancerCenter@TuftsMedicalCenter.org

    Gloucester

    Addison Gilbert Hospital

    Angus P. McIntyre
    Ph: 978-283-4000ext559

    Springfield

    Baystate Medical Center

    Syed S Ali
    Ph: 413-794-3565
    Email: tamara.wrenn@baystatehealth.org

    Worcester

    UMASS Memorial Cancer Center - University Campus

    Muthalagu Ramanathan
    Ph: 508-856-3216
    Email: cancer.research@umassmed.edu

    Michigan
    Adrian

    Hickman Cancer Center at Bixby Medical Center

    Rex B Mowat
    Ph: 800-444-3561

    Ann Arbor

    Saint Joseph Mercy Cancer Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Dearborn

    Oakwood Cancer Center at Oakwood Hospital and Medical Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Detroit

    Van Elslander Cancer Center at St. John Hospital and Medical Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Wayne State University

    Jay Yang
    Ph: 313-576-9363

    Escanaba

    Green Bay Oncology, Limited - Escanaba

    Brian L Burnette
    Ph: 800-432-6049

    Farmington

    Botsford Oncology Practice at Botsford General Hospital

    Susanna S Gaikazian
    Ph: 248-551-7695

    Farmington Hills

    Weisberg Cancer Treatment Center

    Jay Yang
    Ph: 313-576-9363

    Flint

    Genesys Hurley Cancer Institute

    Christopher M Reynolds
    Ph: 734-712-4673

    Hurley Medical Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Iron Mountain

    Green Bay Oncology - Iron Mountain

    Brian L Burnette
    Ph: 800-432-6049

    Jackson

    Gayle M. Jacob Cancer Center at Allegiance Health

    Christopher M Reynolds
    Ph: 734-712-4673

    Kalamazoo

    West Michigan Cancer Center

    Sunil Nagpal
    Ph: 269-373-7458

    Lansing

    Sparrow Regional Cancer Center

    Christopher M Reynolds
    Ph: 734-712-4673

    Livonia

    St. Mary Mercy Hospital

    Christopher M Reynolds
    Ph: 734-712-4673

    Monroe

    Community Cancer Center of Monroe

    Rex B Mowat
    Ph: 800-444-3561

    Pontiac

    St. Joseph Mercy Oakland

    Christopher M Reynolds
    Ph: 734-712-4673

    Port Huron

    Mercy Regional Cancer Center at Mercy Hospital

    Christopher M Reynolds
    Ph: 734-712-4673

    Roseville

    Michigan Cancer Specialists

    Susanna S Gaikazian
    Ph: 248-551-7695

    Royal Oak

    Cancer Care Associates - Royal Oak

    Susanna S Gaikazian
    Ph: 248-551-7695

    Comprehensive Medical Center PLLC

    Susanna S Gaikazian
    Ph: 248-551-7695

    Hematology-Oncology Consultants - Royal Oak

    Susanna S Gaikazian
    Ph: 248-551-7695

    Oakland Colon and Rectal Associates, PC

    Susanna S Gaikazian
    Ph: 248-551-7695

    Oakland Medical Group

    Susanna S Gaikazian
    Ph: 248-551-7695

    William Beaumont Hospital - Royal Oak Campus

    Susanna S Gaikazian
    Ph: 248-551-7695

    Saginaw

    Seton Cancer Institute at Saint Mary's - Saginaw

    Christopher M Reynolds
    Ph: 734-712-4673

    Sterling Heights

    Mitchell Folbe MD PC

    Susanna S Gaikazian
    Ph: 248-551-7695

    Premier Hematology Oncology Care

    Susanna S Gaikazian
    Ph: 248-551-7695

    Troy

    Claudia BR Herke MD PC

    Susanna S Gaikazian
    Ph: 248-551-7695

    Hematology Oncology Consultants - Troy

    Susanna S Gaikazian
    Ph: 248-551-7695

    Michigan Institute of Urology, PC - Troy

    Susanna S Gaikazian
    Ph: 248-551-7695

    William Beaumont Hospital - Troy Campus

    Susanna S Gaikazian
    Ph: 248-551-7695

    Warren

    St. John Macomb Hospital

    Christopher M Reynolds
    Ph: 734-712-4673

    Minnesota
    Bemidji

    MeritCare Bemidji

    Preston D. Steen
    Ph: 701-234-6161

    Brainerd

    St. Joseph's Medical Center

    Bret E Friday
    Ph: 888-203-7267

    Burnsville

    Fairview Ridges Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Coon Rapids

    Mercy and Unity Cancer Center at Mercy Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Duluth

    CCOP - Duluth

    Bret E Friday
    Ph: 888-203-7267

    Essentia Health - Duluth Clinic

    Bret E Friday
    Ph: 888-203-7267

    Miller - Dwan Medical Center

    Bret E Friday
    Ph: 888-203-7267

    Edina

    Fairview Southdale Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Fergus Falls

    Lake Region Healthcare Corporation-Cancer Care

    Bret E Friday
    Ph: 888-203-7267

    Fridley

    Mercy and Unity Cancer Center at Unity Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Hutchinson

    Hutchinson Area Health Care

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Maplewood

    HealthEast Cancer Care at St. John's Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Minnesota Oncology - Maplewood

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Minneapolis

    Health Partners Inc

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Hennepin County Medical Center - Minneapolis

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Virginia Piper Cancer Institute at Abbott - Northwestern Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    New Ulm

    New Ulm Medical Center

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Robbinsdale

    Humphrey Cancer Center at North Memorial Outpatient Center

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Rochester

    Mayo Clinic Cancer Center

    Tait D. Shanafelt
    Ph: 507-538-7623

    Saint Louis Park

    Park Nicollet Cancer Center

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Saint Paul

    Regions Hospital Cancer Care Center

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    United Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Shakopee

    St. Francis Cancer Center at St. Francis Medical Center

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Stillwater

    Lakeview Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Waconia

    Ridgeview Medical Center

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Willmar

    Willmar Cancer Center at Rice Memorial Hospital

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Woodbury

    Minnesota Oncology - Woodbury

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Missouri
    Bolivar

    Central Care Cancer Center at Carrie J. Babb Cancer Center

    Jay W Carlson
    Ph: 800-821-7532

    Bonne Terre

    Parkland Health Center-Bonne Terre

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Branson

    Skaggs Cancer Center at Skaggs Regional Medical Center

    Jay W Carlson
    Ph: 800-821-7532

    Cape Girardeau

    Saint Francis Medical Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Southeast Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Jefferson City

    Goldschmidt Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Joplin

    Freeman Cancer Institute at Freeman Health System

    Jay W Carlson
    Ph: 800-821-7532

    St. John's Regional Medical Center

    Jay W Carlson
    Ph: 800-821-7532

    Rolla

    Mercy Clinic Cancer and Hematology - Rolla

    Jay W Carlson
    Ph: 800-821-7532

    Phelps County Regional Medical Center

    Jay W Carlson
    Ph: 800-821-7532

    Saint Louis

    David C. Pratt Cancer Center at St. John's Mercy

    Jay W Carlson
    Ph: 800-821-7532

    Mercy Clinic St. Louis Cancer and Breast Institute

    Jay W Carlson
    Ph: 800-821-7532

    Missouri Baptist Cancer Center

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis

    Nancy L. Bartlett
    Ph: 800-600-3606
    Email: info@siteman.wustl.edu

    Sainte Genevieve

    Sainte Genevieve County Memorial Hospital

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Springfield

    Hulston Cancer Center at Cox Medical Center South

    Jay W Carlson
    Ph: 800-821-7532

    St. John's Regional Health Center

    Jay W Carlson
    Ph: 800-821-7532

    Sullivan

    Missouri Baptist Sullivan Hospital

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Sunset Hills

    Missouri Baptist Outpatient Center-Sunset Hills

    James L. Wade
    Ph: 217-876-4740
    Email: kcheek@dmhhs.org

    Montana
    Billings

    Billings Clinic Cancer Center - 801 N 29th Street

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    CCOP - Montana Cancer Consortium

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    St. Vincent Healthcare Cancer Care Services

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Bozeman

    Bozeman Deaconess Cancer Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Butte

    St. James Healthcare Cancer Care

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Great Falls

    Benefis Sletten Cancer Institute

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Helena

    St. Peter's Hospital

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Kalispell

    Kalispell Regional Medical Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Missoula

    Montana Cancer Center at St. Patrick Hospital and Health Sciences Center

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Nebraska
    Grand Island

    Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Kearney

    Good Samaritan Cancer Center at Good Samaritan Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Heartland Hematology and Oncology

    Mehmet S. Copur
    Ph: 800-998-2119

    Lincoln

    Cancer Resource Center - Lincoln

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Nebraska Hematology and Oncology

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Saint Elizabeth Cancer Institute at Saint Elizabeth Regional Medical Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Southeast Nebraska Hematology Oncology Consultants at Southeast Nebraska Cancer Center

    Gamini S. Soori
    Ph: 402-991-8070
    Email: mwilwerding@mvcc.cc

    Norfolk

    Carson Cancer Center at Faith Regional Hospital

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    North Platte

    Callahan Cancer Center at Great Plains Regional Medical Center

    Gamini S. Soori
    Ph: 402-991-8070
    Email: mwilwerding@mvcc.cc

    Omaha

    Alegant Health Cancer Center at Bergan Mercy Medical Center

    Mehmet S. Copur
    Ph: 800-998-2119

    CCOP - Missouri Valley Cancer Consortium

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Creighton University Medical Center

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Fred and Pamela Buffett Cancer Center

    Robert Bociek
    Ph: 402-559-6941
    Email: unmcrsa@unmc.edu

    Hematology/Oncology Consultants

    Mehmet S. Copur
    Ph: 800-998-2119

    Immanuel Medical Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Lakeside Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Oncology Hematology West PC

    Gamini S. Soori
    Ph: 402-991-8070
    Email: mwilwerding@mvcc.cc

    Oncology Hematology West, PC - Omaha Bergan

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Papillion

    Midlands Cancer Center at Midlands Community Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Scottsbluff

    Cancer Treatment Center at Regional West Medical Center

    Gamini S. Soori
    Ph: 402-991-8070ext202
    Email: mwilwerding@mvcc.cc

    Nevada
    Henderson

    21st Century Oncology - Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada-Southeast Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Las Vegas Cancer Center - Henderson

    John Allan Ellerton
    Ph: 702-384-0013

    Las Vegas

    21st Century Oncology - Fort Apache

    John Allan Ellerton
    Ph: 702-384-0013

    21st Century Oncology - Vegas Sunrise

    John Allan Ellerton
    Ph: 702-384-0013

    21st Century Oncology - Vegas Tenaya

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Fort Apache

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Shadow

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer and Blood Specialists-Tenaya

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer Institute of Nevada at Summerlin Hospital Medical Center

    John Allan Ellerton
    Ph: 702-384-0013

    John Allan Ellerton
    Ph: 702-384-0013

    Cancer Therapy and Integrative Medicine

    John Allan Ellerton
    Ph: 702-384-0013

    CCOP - Nevada Cancer Research Foundation

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Central Valley

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Northwest

    John Allan Ellerton
    Ph: 702-384-0013

    Comprehensive Cancer Centers of Nevada - Southwest

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-San Martin

    John Allan Ellerton
    Ph: 702-384-0013

    HealthCare Partners Medical Group Oncology/Hematology-Tenaya

    John Allan Ellerton
    Ph: 702-384-0013

    Las Vegas Cancer Center-Medical Center

    John Allan Ellerton
    Ph: 702-384-0013

    Radiation Oncology Centers of Las Vegas - Downtown Location

    John Allan Ellerton
    Ph: 702-384-0013

    Radiation Oncology Centers of Las Vegas - Eastern Location

    John Allan Ellerton
    Ph: 702-384-0013

    New Hampshire
    Dover

    Seacoast Cancer Center at Wentworth - Douglass Hospital

    Taylor M Ortiz
    Ph: 603-740-2150

    New Jersey
    East Orange

    Veterans Affairs Medical Center - East Orange

    Victor T Chang
    Ph: 800-475-2336
    Email: patricia.goyer@med.va.gov

    Newark

    Newark Beth Israel Medical Center

    Lori Schleicher
    Ph: 973-926-7230

    New Mexico
    Albuquerque

    University of New Mexico Cancer Center

    Cecilia Y Arana Yi
    Ph: 505-272-6972

    New York
    Albany

    New York Oncology Hematology, PC at Albany Medical Center

    Charles H Weissman
    Ph: 518-489-3612
    Email: gerryann.currier@usoncology.com

    Auburn

    Hematology Oncology Associates of Central New York-Auburn

    Jeffrey J. Kirshner
    Ph: 315-472-7504

    Glens Falls

    Charles R. Wood Cancer Center at Glens Falls Hospital

    Mark M. Hoffman
    Ph: 518-926-6700

    Manhasset

    Don Monti Comprehensive Cancer Center at North Shore University Hospital

    Jacqueline C Barrientos
    Ph: 516-562-3467

    Middletown

    Tucker Center for Cancer Care at Orange Regional Medical Center

    Jeffrey M. Stewart
    Ph: 845-342-7609

    New Hyde Park

    Long Island Jewish Medical Center

    Jacqueline C Barrientos
    Ph: 516-562-3467

    Monter Cancer Center of the North Shore-LIJ Health System

    Jacqueline C Barrientos
    Ph: 516-562-3467

    Rochester

    James P. Wilmot Cancer Center at University of Rochester Medical Center

    Jonathan W Friedberg
    Ph: 585-275-5830

    Syracuse

    Hematology Oncology Associates of Central New York-Onondaga Hill

    Jeffrey J. Kirshner
    Ph: 315-472-7504

    SUNY Upstate Medical University Hospital

    Teresa C. Gentile
    Ph: 315-464-5476

    North Carolina
    Asheville

    Cancer Care of Western North Carolina

    Christopher H Chay
    Ph: 828-213-4150

    Mission Hospitals - Memorial Campus

    Christopher H Chay
    Ph: 828-213-4150

    Clinton

    Sampson Radiation Oncology

    James N. Atkins
    Ph: 919-580-0000

    Southeastern Medical Oncology Center-Clinton

    James N. Atkins
    Ph: 919-580-0000

    Goldsboro

    Southeastern Medical Oncology Center - Goldsboro

    James N. Atkins
    Ph: 919-580-0000

    Wayne Memorial Hospital, Incorporated

    James N. Atkins
    Ph: 919-580-0000

    Wayne Radiation Oncology

    James N. Atkins
    Ph: 919-580-0000

    Hendersonville

    Comprehensive Cancer Center at Pardee Hospital

    James E. Radford
    Ph: 828-696-4716

    Hendersonville Hematology and Oncology

    James E. Radford
    Ph: 828-696-4716

    Jacksonville

    Onslow Memorial Hospital

    James N. Atkins
    Ph: 919-580-0000

    Southeastern Medical Oncology Center-Jacksonville

    James N. Atkins
    Ph: 919-580-0000

    Kinston

    Kinston Medical Specialists

    Peter R. Watson
    Ph: 252-559-2200

    Wilson

    Southeastern Medical Oncology Center - Wilson

    James N. Atkins
    Ph: 919-580-0000

    Winston-Salem

    Wake Forest University Comprehensive Cancer Center

    Leslie R Ellis
    Ph: 336-713-6771

    North Dakota
    Bismarck

    Medcenter One Hospital Cancer Care Center

    Preston D. Steen
    Ph: 701-234-6161

    Fargo

    Dakota Cancer Institute at Dakota Clinic - South University

    Bret E Friday
    Ph: 888-203-7267

    Roger Maris Cancer Center at MeritCare Hospital

    Preston D. Steen
    Ph: 701-234-6161

    Preston D. Steen
    Ph: 701-234-6161

    Sanford Clinic North-Fargo

    Preston D. Steen
    Ph: 701-234-6161

    Ohio
    Beachwood

    UHHS Chagrin Highlands Medical Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Belpre

    Strecker Cancer Center-Belpre

    J. Philip Kuebler
    Ph: 614-566-3275

    Centerville

    Miami Valley Hospital South

    Howard M. Gross
    Ph: 937-775-1350

    Chardon

    Geauga Regional Hospital

    Hillard M. Lazarus
    Ph: 800-641-2422

    Chillicothe

    Adena Regional Medical Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Cincinnati

    Bethesda North Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Good Samaritan Hospital Cancer Treatment Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Oncology Hematology Care Inc - Western Hills

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Anderson

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Blue Ash

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Kenwood

    Howard M. Gross
    Ph: 937-775-1350

    Oncology Hematology Care, Incorporated - Mt. Auburn/Taft Road

    Howard M. Gross
    Ph: 937-775-1350

    TriHealth Cancer Institute-Anderson

    Mehmet S. Copur
    Ph: 800-998-2119

    TriHealth Cancer Institute-Westside

    Mehmet S. Copur
    Ph: 800-998-2119

    Cleveland

    Case Comprehensive Cancer Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Columbus

    Columbus Oncology Associates, Incorporated

    J. Philip Kuebler
    Ph: 614-566-3275

    Doctors Hospital at Ohio Health

    J. Philip Kuebler
    Ph: 614-566-3275

    Grant Medical Center Cancer Care

    J. Philip Kuebler
    Ph: 614-566-3275

    Mount Carmel Health - West Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Riverside Methodist Hospital Cancer Care

    J. Philip Kuebler
    Ph: 614-566-3275

    Zangmeister Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Dayton

    David L. Rike Cancer Center at Miami Valley Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Good Samaritan Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Samaritan North Cancer Care Center

    Howard M. Gross
    Ph: 937-775-1350

    Delaware

    Delaware Health Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Delaware Radiation Oncology

    J. Philip Kuebler
    Ph: 614-566-3275

    Grady Memorial Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Elyria

    Mercy Cancer Center - Elyria

    Hillard M. Lazarus
    Ph: 800-641-2422

    Fairfield

    Oncology Hematology Care, Incorporated - Fairfield Healthplex

    Howard M. Gross
    Ph: 937-775-1350

    Findlay

    Blanchard Valley Regional Cancer Center

    Howard M. Gross
    Ph: 937-775-1350

    Franklin

    Atrium Medical Center

    Howard M. Gross
    Ph: 937-775-1350

    Greenville

    Wayne Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Kettering

    Charles F. Kettering Memorial Hospital

    Howard M. Gross
    Ph: 937-775-1350

    Lancaster

    Fairfield Medical Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Marietta

    Strecker Cancer Center at Marietta Memorial Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Maumee

    Northwest Ohio Oncology Center

    Rex B Mowat
    Ph: 800-444-3561

    Rex B Mowat
    Ph: 800-444-3561

    Mayfield Heights

    University Hospitals Ireland Cancer Center at Landerbrook Health Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Mentor

    Lake/University Ireland Cancer Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Middleburg Heights

    Southwest General Health Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Mount Vernon

    Knox Community Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Newark

    Licking Memorial Cancer Care Program at Licking Memorial Hospital

    J. Philip Kuebler
    Ph: 614-566-3275

    Newark Radiation Oncology

    J. Philip Kuebler
    Ph: 614-566-3275

    Oregon

    St. Charles Mercy Hospital

    Rex B Mowat
    Ph: 800-444-3561

    Parma

    Parma Community General Hospital

    Hillard M. Lazarus
    Ph: 800-641-2422

    Portsmouth

    Southern Ohio Medical Center Cancer Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Springfield

    Community Hospital of Springfield and Clark County

    J. Philip Kuebler
    Ph: 614-566-3275

    Sylvania

    Flower Hospital Cancer Center

    Rex B Mowat
    Ph: 800-444-3561

    Toledo

    CCOP - Toledo Community Hospital

    Rex B Mowat
    Ph: 800-444-3561

    St. Anne Mercy Hospital

    Rex B Mowat
    Ph: 800-444-3561

    Toledo Clinic, Incorporated - Main Clinic

    Rex B Mowat
    Ph: 800-444-3561

    University of Toledo Medical Center

    Rex B Mowat
    Ph: 800-444-3561

    Troy

    UVMC Cancer Care Center at Upper Valley Medical Center

    Howard M. Gross
    Ph: 937-775-1350

    Wadsworth

    University Hospitals Sharon Health Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Westerville

    Mount Carmel St. Ann's Cancer Center

    J. Philip Kuebler
    Ph: 614-566-3275

    Westlake

    UH-Seidman Cancer Center at Saint John Medical Center

    Hillard M. Lazarus
    Ph: 800-641-2422

    Zanesville

    Genesis - Good Samaritan Hospital

    J. Philip Kuebler
    Ph: 614-488-2745
    Email: sheree@columbusccop.org

    Oklahoma
    Lawton

    Cancer Centers of Southwest Oklahoma, LLC - Lawton

    Nadim F. Nimeh
    Ph: 877-231-4440

    Oklahoma City

    Stephenson Cancer Center at the University of Oklahoma

    Mohamad Cherry
    Ph: 405-271-4272
    Email: julie-traylor@ouhsc.edu

    Oregon
    Clackamas

    Clackamas Radiation Oncology Center

    Keith S. Lanier
    Ph: 503-215-6412

    Providence Oncology and Hematology Care Southeast

    Keith S. Lanier
    Ph: 503-215-6412

    Newberg

    Providence Newberg Medical Center

    Keith S. Lanier
    Ph: 503-215-6412

    Oregon City

    Willamette Falls Hospital

    Keith S. Lanier
    Ph: 503-215-6412

    Portland

    Kaiser Permanente Health Care - Portland

    Nagendra Tirumali
    Ph: 503-335-2400

    Providence Cancer Center at Providence Portland Medical Center

    Keith S. Lanier
    Ph: 503-215-6412

    Providence St. Vincent Medical Center

    Keith S. Lanier
    Ph: 503-215-6412

    Pennsylvania
    Allentown

    Morgan Cancer Center at Lehigh Valley Hospital - Cedar Crest

    Eliot Lawrence Friedman
    Ph: 610-402-2273

    Beaver

    UPMC Cancer Center at Beaver Medical Center

    Alison R Sehgal
    Ph: 412-647-8073

    Bethlehem

    Lehigh Valley Hospital - Muhlenberg

    Eliot Lawrence Friedman
    Ph: 610-402-2273

    Bryn Mawr

    Bryn Mawr Hospital

    Albert S DeNittis
    Ph: 866-225-5654

    Chadds Ford

    Christiana Care Concord Health Center

    Stephen Scott Grubbs
    Ph: 302-733-6227

    Clairton

    UPMC Cancer Center at Jefferson Regional Medical Center

    Alison R Sehgal
    Ph: 412-647-8073

    Danville

    Geisinger Cancer Institute at Geisinger Health

    Edward J Gorak
    Ph: 570-271-5251

    Greensburg

    UPMC Cancer Center - Arnold Palmer Pavilion

    Alison R Sehgal
    Ph: 412-647-8073

    Hazleton

    Geisinger Hazleton Cancer Center

    Edward J Gorak
    Ph: 570-271-5251

    Hershey

    Penn State Hershey Cancer Institute at Milton S. Hershey Medical Center

    Jeffrey J Pu
    Ph: 717-531-3779
    Email: CTO@hmc.psu.edu

    Johnstown

    UPMC Cancer Center at the John P. Murtha Pavilion

    Alison R Sehgal
    Ph: 412-647-8073

    Lancaster

    Lancaster General Hospital

    Shyam S Balepur
    Ph: 717-544-0511

    Lewisburg

    Geisinger Medical Oncology at Evangelical Community Hospital

    Edward J Gorak
    Ph: 570-271-5251

    Lewistown

    Lewistown Hospital

    Edward J Gorak
    Ph: 570-271-5251

    McKeesport

    UPMC Cancer Center at UPMC McKeesport

    Alison R Sehgal
    Ph: 412-647-8073

    Media

    Riddle Memorial Hospital Cancer Center

    Albert S DeNittis
    Ph: 866-225-5654

    Moon Township

    UPMC - Moon

    Alison R Sehgal
    Ph: 412-647-8073

    Paoli

    Cancer Center of Paoli Memorial Hospital

    Albert S DeNittis
    Ph: 866-225-5654

    Philadelphia

    Abramson Cancer Center of the University of Pennsylvania

    Anthony R Mato
    Ph: 800-474-9892

    Kimmel Cancer Center at Thomas Jefferson University - Philadelphia

    Amy R Mackenzie
    Ph: 215-955-6084

    Pittsburgh

    St. Clair Memorial Hospital Cancer Center

    Alison R Sehgal
    Ph: 412-647-8073

    UPMC - Shadyside

    Alison R Sehgal
    Ph: 412-647-8073

    UPMC Cancer Center at Magee-Womens Hospital

    Alison R Sehgal
    Ph: 412-647-8073

    UPMC Cancer Center at UPMC Passavant

    Alison R Sehgal
    Ph: 412-647-8073

    UPMC Cancer Center at UPMC Presbyterian

    Alison R Sehgal
    Ph: 412-647-8073

    UPMC Cancer Center at UPMC St. Margaret

    Alison R Sehgal
    Ph: 412-647-8073

    UPMC Cancer Centers

    Alison R Sehgal
    Ph: 412-647-8073

    Pottstown

    Pottstown Memorial Regional Cancer Center

    Wei Song
    Ph: 610-327-7544

    Pottsville

    Geisinger Medical Oncology-Pottsville

    Edward J Gorak
    Ph: 570-271-5251

    Scranton

    Hematology and Oncology Associates of North East Pennsylvania

    Amy R Mackenzie
    Ph: 215-955-6084

    Seneca

    UPMC Cancer Center at UPMC Northwest

    Alison R Sehgal
    Ph: 412-647-8073

    State College

    Geisinger Medical Group - Scenery Park

    Edward J Gorak
    Ph: 570-271-5251

    Uniontown

    UPMC Cancer Center - Uniontown

    Alison R Sehgal
    Ph: 412-647-8073

    Washington

    Washington Hospital Cancer Center

    Alison R Sehgal
    Ph: 412-647-8073

    West Reading

    McGlinn Family Regional Cancer Center at Reading Hospital and Medical Center

    Terrence P. Cescon
    Ph: 610-988-9323

    Wilkes-Barre

    Frank M. and Dorothea Henry Cancer Center at Geisinger Wyoming Valley Medical Center

    Edward J Gorak
    Ph: 570-271-5251

    Williamsport

    Susquehanna Cancer Center at Divine Providence Hospital

    Warren L Robinson
    Ph: 800-598-4282

    Wynnewood

    Lankenau Cancer Center at Lankenau Hospital

    Albert S DeNittis
    Ph: 866-225-5654

    South Carolina
    Easley

    Cancer Centers of the Carolinas - Easley

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Greenville

    Bon Secours St. Francis Health System

    Robert D. Siegel
    Ph: 864-255-1713

    Cancer Centers of the Carolinas - Andrews

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Cancer Centers of the Carolinas - Faris Road

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Cancer Centers of the Carolinas - Grove Commons

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    CCOP - Greenville

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Greenville Memorial Hospital

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Saint Francis Cancer Center

    Robert D. Siegel
    Ph: 864-255-1713

    Greer

    Cancer Centers of the Carolinas - Greer Radiation Oncology

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Seneca

    Cancer Centers of the Carolinas - Seneca

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    Spartanburg

    Cancer Centers of the Carolinas - Spartanburg

    Jeffrey Kent Giguere
    Ph: 864-241-6251

    South Dakota
    Rapid City

    Rapid City Regional Hospital

    Joshua C Lukenbill
    Ph: 605-716-3982
    Email: research@rcrh.org

    Sioux Falls

    Avera Cancer Institute

    Addison R Tolentino
    Ph: 800-657-4377
    Email: Jan.Healy@avera.org

    Sanford Cancer Center at Sanford USD Medical Center

    Preston D. Steen
    Ph: 701-234-6161

    Preston D. Steen
    Ph: 701-234-6161

    Tennessee
    Bristol

    Wellmont-Bristol Regional Medical Center

    Asheesh Shipstone
    Ph: 423-578-8538

    Chattanooga

    H. Clay Evans Johnson Cancer Center at Memorial Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Hixson

    Pulmonary Medicine Center of Chattanooga-Hixson

    Mehmet S. Copur
    Ph: 800-998-2119

    Johnson City

    Wellmont Medical Associates Oncology and Hematology-Johnson City

    Asheesh Shipstone
    Ph: 423-578-8538

    Kingsport

    Christine LaGuardia Phillips Cancer Center at Wellmont Holston Valley Medical Center

    Asheesh Shipstone
    Ph: 423-578-8538

    Kingsport Hematology-Oncology Associates

    Asheesh Shipstone
    Ph: 423-578-8538

    Nashville

    MBCCOP - Meharry Medical College - Nashville

    Philip E Lammers
    Ph: 615-327-5724
    Email: jmurray@mmc.edu

    Ooltewah

    Memorial GYN Plus

    Mehmet S. Copur
    Ph: 800-998-2119

    Texas
    Amarillo

    Harrington Cancer Center

    Stewart Allen Sharp
    Ph: 806-359-4673
    Email: ryokubaitis@harringtoncc.org

    Dallas

    Parkland Memorial Hospital

    Harris V Naina
    Ph: 214-648-7097

    Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas

    Harris V Naina
    Ph: 214-648-7097

    Lubbock

    Covenant Medical Center

    Donald P Quick
    Ph: 806-725-8000
    Email: jaccresearch@covhs.org

    San Antonio

    University Hospital - San Antonio

    Anand B. Karnad
    Ph: 210-450-3800

    University of Texas Health Science Center at San Antonio

    Anand B. Karnad
    Ph: 210-450-3800

    Vermont
    Berlin

    Mountainview Medical

    George F Atweh
    Ph: 802-656-4101

    Burlington

    University of Vermont Cancer Center

    George F Atweh
    Ph: 802-656-4101

    Virginia
    Danville

    Danville Hematology and Oncology, Incorporated

    Ashantice K Higgins
    Ph: 434-793-0044

    Fredericksburg

    Hematology Oncology Associates of Fredericksburg Inc

    Beata Holkova
    Ph: 804-628-1939

    Lynchburg

    Lynchburg Hematology-Oncology Clinic

    Beata Holkova
    Ph: 804-628-1939

    Martinsville

    Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County

    Sreedhar Katragadda
    Ph: 276-666-7827

    Norton

    Southwest Virginia Regional Cancer Center at Wellmonth Health

    Asheesh Shipstone
    Ph: 423-578-8538

    Richmond

    Virginia Cancer Institute - West End

    Beata Holkova
    Ph: 804-628-1939

    Virginia Commonwealth University Massey Cancer Center

    Beata Holkova
    Ph: 804-628-1939

    South Hill

    Community Memorial Health Center

    Beata Holkova
    Ph: 804-628-1939

    Washington
    Auburn

    Auburn Regional Center for Cancer Care

    John A Keech
    Ph: 907-458-5380

    Bainbridge Island

    Virginia Mason Bainbridge Island Medical Center

    John A Keech
    Ph: 907-458-5380

    Bellevue

    Overlake Cancer Center at Overlake Hospital Medical Center

    John A Keech
    Ph: 907-458-5380

    Bellingham

    St. Joseph Cancer Center

    Michael Andre Taylor
    Ph: 360-788-8223
    Email: cpatz@peacehealth.org

    Bremerton

    Harrison Medical Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Olympic Hematology and Oncology

    Mehmet S. Copur
    Ph: 800-998-2119

    Burien

    Highline Medical Center Cancer Center

    Mehmet S. Copur
    Ph: 800-998-2119

    Enumclaw

    Saint Elizabeth Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Federal Way

    St. Francis Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Virginia Mason Federal Way Medical Center

    John A Keech
    Ph: 907-458-5380

    Gig Harbor

    MultiCare Gig Harbor Medical Park

    John A Keech
    Ph: 907-458-5380

    Tacoma/Valley Radiation Oncology Centers-Gig Harbor

    John A Keech
    Ph: 907-458-5380

    Kennewick

    Northwest Cancer Clinic

    John A Keech
    Ph: 907-458-5380

    Lakewood

    St. Clare Hospital

    Mehmet S. Copur
    Ph: 800-998-2119

    Longview

    Lower Columbia Regional Cancer Center at PeaceHealth-St. John Medical Center

    Keith S. Lanier
    Ph: 503-215-6412

    Lynnwood

    Virginia Mason Lynnwood Medical Center

    John A Keech
    Ph: 907-458-5380

    Poulsbo

    Harrison Poulsbo Hematology and Onocology

    Mehmet S. Copur
    Ph: 800-998-2119

    Peninsula Cancer Center

    John A Keech
    Ph: 907-458-5380

    Puyallup

    Good Samaritan Cancer Center

    John A Keech
    Ph: 907-458-5380

    Takoma/Valley Radiation Oncology Center at Good Samaritan

    John A Keech
    Ph: 907-458-5380

    Seattle

    Virginia Mason Medical Center

    John A Keech
    Ph: 907-458-5380

    Tacoma

    Franciscan Research Center-Northwest Medical Plaza

    Mehmet S. Copur
    Ph: 800-998-2119

    MultiCare Regional Cancer Center at Tacoma General Hospital

    John A Keech
    Ph: 907-458-5380

    Northwest Medical Specialties, PLLC - Tacoma

    Mehmet S. Copur
    Ph: 800-998-2119

    Tacoma/Valley Radiation Oncology Center - St. Joseph

    John A Keech
    Ph: 907-458-5380

    Tacoma/Valley Radiation Oncology Centers-Jackson Hall

    John A Keech
    Ph: 907-458-5380

    Vancouver

    Southwest Washington Medical Center Cancer Center

    Keith S. Lanier
    Ph: 503-215-6412

    West Virginia
    Morgantown

    Mary Babb Randolph Cancer Center at West Virginia University Hospitals

    Abraham S Kanate
    Ph: 304-293-2745
    Email: sfilburn@hsc.wvu.edu

    Wisconsin
    Antigo

    Langlade Memorial Hospital

    Hamied R. Rezazadeh
    Ph: 877-405-6866

    Burlington

    Aurora Cancer Care-Burlington

    Rubina Qamar
    Ph: 888-709-2080

    Chippewa Falls

    Marshfield Clinic - Chippewa Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Eau Claire

    Center for Cancer Treatment & Prevention at Sacred Heart Hospital

    Ali W. Bseiso
    Ph: 715-389-4457

    Marshfield Clinic Cancer Care at Regional Cancer Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Elkhorn

    Vince Lombardi Cancer Center at Aurora Lakeland Medical Center - Elkhorn

    Rubina Qamar
    Ph: 888-709-2080

    Fond Du Lac

    Aurora Health Center-Fond du Lac

    Rubina Qamar
    Ph: 888-709-2080

    Grafton

    Aurora Cancer Care-Grafton

    Rubina Qamar
    Ph: 888-709-2080

    Green Bay

    Bellin Memorial Hospital

    Patrick J Mansky
    Ph: 240-566-3584
    Email: clinicaltrials@fmh.org

    Green Bay Oncology, Limited at St. Mary's Hospital

    Brian L Burnette
    Ph: 800-432-6049

    Green Bay Oncology, Limited at St. Vincent Hospital Regional Cancer Center

    Brian L Burnette
    Ph: 800-432-6049

    St. Mary's Hospital Medical Center - Green Bay

    Brian L Burnette
    Ph: 800-432-6049

    St. Vincent Hospital Regional Cancer Center

    Brian L Burnette
    Ph: 800-432-6049

    Vince Lombardi Cancer Clinic - Green Bay at Aurora BayCare Medical Center

    Rubina Qamar
    Ph: 888-709-2080

    Kenosha

    Oncology Alliance - Kenosha South

    Rubina Qamar
    Ph: 888-709-2080

    La Crosse

    Gundersen Lutheran Center for Cancer and Blood

    Kurt Oettel
    Ph: 608-775-2385
    Email: cancerctr@gundluth.org

    Ladysmith

    Marshfield Clinic - Ladysmith Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Manitowoc

    Holy Family Memorial Medical Center Cancer Care Center

    Brian L Burnette
    Ph: 800-432-6049

    Marinette

    Vince Lombardi Cancer Clinic - Marinette

    Rubina Qamar
    Ph: 888-709-2080

    Marshfield

    Marshfield Clinic - Marshfield Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Saint Joseph's Hospital

    Ali W. Bseiso
    Ph: 715-389-4457

    Menomonee Falls

    Aurora Advanced Healthcare Inc-Menomonee Falls

    Rubina Qamar
    Ph: 888-709-2080

    Milwaukee

    Aurora Cancer Care-Milwaukee

    Rubina Qamar
    Ph: 888-709-2080

    Aurora Sinai Medical Center

    Rubina Qamar
    Ph: 888-709-2080

    Froedtert Hospital and Medical College of Wisconsin

    Laura C Michaelis
    Ph: 414-805-4380

    Oncology Alliance, SC - Milwaukee - South

    Rubina Qamar
    Ph: 888-709-2080

    Vince Lombardi Cancer Clinic at Aurora St. Luke's Medical Center

    Rubina Qamar
    Ph: 888-709-2080

    Minocqua

    Marshfield Clinic - Lakeland Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Mukwonago

    D.N. Greenwald Center

    Timothy R Wassenaar
    Ph: 262-928-7878

    New Richmond

    Cancer Center of Western Wisconsin

    Joseph W Leach
    Ph: 952-993-1517
    Email: MMCCOP@parknicollet.com

    Oconomowoc

    Regional Cancer Center at Oconomowoc Memorial Hospital

    Timothy R Wassenaar
    Ph: 262-928-7878

    Oconto Falls

    Green Bay Oncology, Limited - Oconto Falls

    Brian L Burnette
    Ph: 800-432-6049

    Oshkosh

    Vince Lombardi Cancer Clinic - Oshkosh

    Rubina Qamar
    Ph: 888-709-2080

    Racine

    Aurora Health Center - Racine

    Rubina Qamar
    Ph: 888-709-2080

    Rhinelander

    Ministry Medical Group at Saint Mary's Hospital

    Ali W. Bseiso
    Ph: 715-389-4457

    Ali W. Bseiso
    Ph: 715-389-4457

    Rice Lake

    Marshfield Clinic - Indianhead Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Sheboygan

    Saint Nicholas Hospital

    Brian L Burnette
    Ph: 800-432-6049

    Vince Lombardi Cancer Clinic - Sheboygan

    Rubina Qamar
    Ph: 888-709-2080

    Stevens Point

    Marshfield Clinic at Saint Michael's Hospital

    Ali W. Bseiso
    Ph: 715-389-4457

    Saint Michael's Hospital Cancer Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Sturgeon Bay

    Green Bay Oncology, Limited - Sturgeon Bay

    Brian L Burnette
    Ph: 800-432-6049

    Summit

    Aurora Medical Center

    Rubina Qamar
    Ph: 888-709-2080

    Two Rivers

    Vince Lombardi Cancer Clinic - Two Rivers

    Rubina Qamar
    Ph: 888-709-2080

    Waukesha

    Aurora Cancer Care-Waukesha

    Rubina Qamar
    Ph: 888-709-2080

    Waukesha Memorial Hospital Regional Cancer Center

    Timothy R Wassenaar
    Ph: 262-928-7878

    Wausau

    Marshfield Clinic - Wausau Center

    Ali W. Bseiso
    Ph: 715-389-4457

    University of Wisconcin Cancer Center at Aspirus Wausau Hospital

    Hamied R. Rezazadeh
    Ph: 877-405-6866

    Wauwatosa

    Oncology Alliance, SC - Milwaukee - West

    Rubina Qamar
    Ph: 888-709-2080

    West Allis

    Aurora Women's Pavilion of West Allis Memorial Hospital

    Rubina Qamar
    Ph: 888-709-2080

    Weston

    Diagnostic and Treatment Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Marshfield Clinic - Weston Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Ministry Saint Clare's Hospital

    Ali W. Bseiso
    Ph: 715-389-4457

    Wisconsin Rapids

    Marshfield Clinic - Wisconsin Rapids Center

    Ali W. Bseiso
    Ph: 715-389-4457

    Riverview UW Cancer Center at Riverview Hospital

    Ron James Kirschling
    Ph: 877-405-6866

    Wyoming
    Cheyenne

    Cheyenne Regional Medical Center

    Keren Sturtz
    Ph: 888-785-6789

    Sheridan

    Welch Cancer Center at Sheridan Memorial Hospital

    Benjamin Thomas Marchello
    Ph: 800-648-6274

    Link to the current ClinicalTrials.gov record.
    NLM Identifier NCT02048813
    ClinicalTrials.gov processed this data on May 19, 2015

    Note: Information about this trial is from the ClinicalTrials.gov database. The versions designated for health professionals and patients contain the same text. Minor changes may be made to the ClinicalTrials.gov record to standardize the names of study sponsors, sites, and contacts. Cancer.gov only lists sites that are recruiting patients for active trials, whereas ClinicalTrials.gov lists all sites for all trials. Questions and comments regarding the presented information should be directed to ClinicalTrials.gov.