We will accelerate the discovery, development, and delivery of cancer prevention interventions by investing in research focused on risk assessment, systems biology, behavior modifications, environmental and policy influences, medical and nutritional approaches, and training and education for research and health professionals.

Prevention is our first line of defense against cancer. Preventing cancer focuses on understanding and modifying behaviors that increase risk, mitigating the influence of genetic and environmental risk factors, and interrupting carcinogenesis through early medical intervention. Dramatic developments in technology and a more complete understanding of the causes and mechanisms of cancer will enable us to provide more effective ways to prevent the disease. Identifying critical molecular pathways of pre-cancers will provide new drug targets for preempting cancer. Transdisciplinary research will provide a more complete understanding of the interplay of molecular, behavioral, genetic, and other factors contributing to cancer susceptibility. We must systematically identify the most promising advances, harness their application for new prevention approaches, and encourage and monitor the adoption of prevention interventions in public health and clinical settings. It is imperative that evidence-based advances shown to inform and motivate people are disseminated and made accessible.

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