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Changing the Conversation

The Nation’s Investment in Cancer Research

Provocative Questions

Due to recent technological advances in many fields, especially in genomics, molecular biology, and computational sciences, there has never been a better time for doing cancer research. We have made large leaps in our basic knowledge about cancers — especially about the genetic and biochemical mechanisms by which they arise. Now we have an opportunity to take a step back from the momentum of these discoveries and make sure we have left no stone unturned and no important but perhaps non-obvious question left unexplored. The new leaders at the NCI are eager to influence the state of cancer research by attempting to define more potentially game-changing scientific questions that could influence the directions taken by NCI-sponsored research in the future.

Related Links

Provocative Questions Project Website.


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NCI Director Harold Varmus, M.D., discusses the Provocative Questions Project and urges researchers to tackle the "perplexing" questions in cancer research. For more information, visit http://provocativequestions.nci.nih.gov

Provocative Questions (PDF) From Cancer | Changing the Conversation: The Nation's Investment in Cancer Research - 2012