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NCI Center for Global Health

United States–Latin America Cancer Research Network (US-LA CRN)

In 2009, NCI formally launched the United States–Latin America Cancer Research Network (US-LA CRN) through signed Letters of Intent (LOI) between the U.S. NCI and institutions in five Latin American countries:

Map of the Americas highlighting the six countries participating in the US-LA CRN: Argentina, Brazil, Chile, Mexico, United States and Uruguay


The first project of the US-LA CRN, "Molecular Profiling of Stage II and III Breast Cancer in Latin American Women receiving Standard of Care Treatment" will generate data that can be used in determining and differentiating the effects of standard therapies on breast cancers in Latin American women. The NCI Center for Global Health (CGH) is utilizing its training program, along with advanced technology and a capacity building program, to implement this study.  

Collaborating on Multiple Levels

CGH envisions a unique approach to forming international scientific partnerships. Successful collaborations require common purpose, adequate resources, and the commitment of governments, foundations, and other stakeholders. CGH's approach—engaging at the government-to-government as well as investigator levels—will build a sustainable, strong partnership among network participants.

Building a Foundation

  • Bringing state-of-the-art cancer research to Latin America including best practice recommendations for establishing biobanks, use of bioinformatics and data management principles, and adherence to high ethical standards
  • Building collaborative relationships across Latin America that will enable the co-development and in-country sustainability of cancer research, including high-quality clinical studies
  • Providing specialized training through workshops and webinars in adapting standards from the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) and other guidelines
  • Increasing the pool of Latin American investigators and providing greater visibility at international cancer meetings and publications in peer-reviewed international scientific journals
  • Creating strong partnerships in Latin America for international cancer research