NCI invites applications that are focused on research leading to the elucidation of mechanism(s) by which dietary factors influence epigenetic processes as well as increasing the understanding of these processes in cancer prevention. The objective is to encourage collaboration between nutrition and epigenetic experts to study bioactive food components with cancer preventive properties and to examine key epigenetic events in cancer processes so that investigators can begin to establish linkages between epigenetics, methylation pattern, and tumor incidence/behavior.
The PA will use the NIH Investigator-Initiated Research Project Grant (R01), the NIH Exploratory/Developmental Grant (R21), and the NIH Small Grants Program (R03) as award mechanisms.
For more information see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=2063
Inquiries: Dr. Sharon A. Ross, email@example.com
Characterization, Behavior, and Plasticity of Pluripotent Stem Cells
NCI, along with other branches of NIH, invites applications for studies on the characterization, behavior, and plasticity of human and nonhuman stem cells; regulation of their replication, differentiation, integration, and function in the nervous system; and identification and characterization of normal and tumor stem cells.
The PA will use the Exploratory/Developmental Grants (R21) mechanism and the Research Project (R01) grant mechanism.
For more information see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=2062
Inquiries: Dr. Neeraja Sathyamoorthy, firstname.lastname@example.org
Phased Application Awards in Cancer Prognosis and Prediction
This PA replaces PAR-03-098. NCI's Cancer Diagnosis Program invites applications for research projects to evaluate the utility and pilot the application of new strategies for determining prognosis or predicting response to therapy, thus providing tools to improve clinical decision-making in the care of cancer patients. This PA provides support for a first phase (R21) for technical development and a second phase (R33) for application and evaluation of clinical utility.
The PA will use the Exploratory/Developmental Research Grant Phase 2 (R33) and the combined R21/R33 Phased-Innovation Award mechanisms.
For more information see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=2060
Testing Tobacco Products Promoted To Reduce Harm
The purpose of this PA is to stimulate multidisciplinary research on potential reduced-exposure tobacco products, both smoked and smokeless, through the interplay of basic, biological, and behavioral research, surveillance, and epidemiology.
The PA will use the NIH Investigator-Initiated Research Project Grant (R01) and the Exploratory/Developmental Grant (R21) award mechanisms.
For more information see http://cri.nci.nih.gov/4abst.cfm?initiativeparfa_id=2061
Inquiries: Dr. Mirjana V. Djordjevic, email@example.com