MRI-Guided Radiotherapy for Prostate Cancer
Name of the Trial
Why This Trial Is Important
In this study, doctors will use a new method called intensity-modulated external-beam radiation therapy (IMRT) to treat men with localized prostate cancer. Patients will undergo a magnetic resonance imaging (MRI) procedure, and doctors will use the resulting images to pinpoint areas of the prostate containing cancer cells. The presence of cancer in these areas will be confirmed with biopsies. Doctors will then treat the areas identified as cancerous with higher doses of radiation, while delivering a standard dose of radiation to the rest of the prostate and surrounding normal tissue.
"When treating prostate cancer, higher radiation doses have produced better outcomes," said Dr. Singh. "This trial is an attempt to use IMRT and MRI imaging, confirmed by MRI-guided biopsy, to direct much higher doses of radiation to those areas of the prostate containing tumor cells. The remainder of the prostate will receive standard radiation doses. This may allow us to more effectively treat the tumor without increasing toxicity to normal tissue."
With this phase I trial, researchers will study the side effects and determine the best dose of MRI-guided radiation therapy for treating patients with prostate cancer.
Who Can Join This Trial
Study Site and Contact Information
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