NEWS
Independent Task Force Updates Recommendations on Breast Cancer Screening
Yesterday, the United States Preventive Services Task Force updated recommendations on breast cancer screening, suggesting that women ages 50 to 74 who are at average risk for getting the disease undergo a routine screening mammogram every 2 years. The recommendations were published in the November 17 Annals of Internal Medicine. Read more > >
New Drug Blocks "Undruggable" Target in Cancer Cells
Compound kills cancer cells by suppressing the Notch signaling pathwayTreatment for Pancreatic Cancer May Target Tumor Microenvironment
Mouse study suggests mechanism to explain earlier trial results in humansSurvey Finds Pain Is Common Years after Breast Cancer Surgery
A nationwide study in Denmark identifies risk factors for chronic pain after surgeryHormone Therapy Use Linked to Benign Breast Condition
Since 2002, rates of atypical ductal hyperplasia have dropped along with hormone useTargeted Treatment Shows Promise for Older Patients with Advanced Leukemia
I131 with CD45 antibody achieves results on par with those in easier-to-treat patientsPotential Strategy for Treating Diffuse Large B-cell Lymphoma Found
Blocking a protein called MALT1 results in the death of certain lymphoma cells
COMMENTARY
Guest Director's Update: Modeling for Research Success
by Dr. Eric J. (Rocky) Feuer
NCI's Cancer Intervention and Surveillance Modeling Network (CISNET) is a large coordinated program that uses complex, multi-cohort modeling to better understand at the population level the impact of both existing and emerging cancer control interventions—whether they are screening modalities or drug therapies or a multi-modal approach to smoking cessation—on trends in cancer incidence and mortality. Nine years since CISNET was launched, this innovative program is providing important insights on the prevention, diagnosis, and treatment of the four most common cancer types: prostate, lung, colorectal, and breast. Read more > >
A MESSAGE TO READERS
Special Issue on Training
Don’t miss our December 1 special issue on training, which will highlight important resources available through NCI’s intramural and extramural programs to help prepare the oncology workforce for the future.
NCI Cancer Bulletin special issues are some of the most popular among our readers. Past special issues have focused on personalized drug development, cancer imaging, and bioinformatics.
IN DEPTH
Exploring the Reasons Women Choose Mastectomies
Several studies examined why patients who were judged to be good candidates for breast-conserving surgery chose mastectomy insteadFeatured Clinical Trial: Combination Therapy for Patients with Myelodysplastic Syndromes
Will combining lenalidomide and epoetin alfa reduce need for transfusions in anemic MDS patients?U.S.-China Cancer Research Collaborations to Be Expanded
At a meeting earlier this month, researchers discussed how to build on this 30 year collaboration in the years ahead
UPDATES
FDA Update
- New Treatment for Rare Skin Cancer Approved by FDA
Cancer.gov Update
- NCI Web Site Consolidates Supportive and Palliative Care Information
Notes
- NCI's Radiation Biology Branch Chief Honored with ASTRO Fellowship
- NIH to Host "Drug Repositioning" Conference Next Month
- 2009 NCI Translational Science Meeting Held
- President's Cancer Panel Explores Genetic Differences in Cancer Burden
The NCI Cancer Bulletin is produced by the National Cancer Institute (NCI), which was established in 1937. Through basic, clinical, and population-based biomedical research and training, NCI conducts and supports research that will lead to a future in which we can identify the environmental and genetic causes of cancer, prevent cancer before it starts, identify cancers that do develop at the earliest stage, eliminate cancers through innovative treatment interventions, and biologically control those cancers that we cannot eliminate so they become manageable, chronic diseases.
For more information about cancer, call 1-800-4-CANCER or visit http://www.cancer.gov.
NCI Cancer Bulletin staff can be reached at ncicancerbulletin@mail.nih.gov.

