National Cancer Institute NCI Cancer Bulletin: A Trusted Source for Cancer Research News
January 26, 2010 • Volume 7 / Number 2

Cancer.gov Update

Recovery Web Site Highlights the NCI Community Cancer Centers Program

The NCI Recovery Act Web site has added new content that highlights the NCI Community Cancer Centers Program (NCCCP) and describes how the program is moving cancer care forward. The site features “Better Cancer Care, Close to Home,” a 5-minute video about the bond between a cancer patient and his cancer team at St. Joseph Cancer Institute in Towson, MD, one of the 16 community cancer centers in the NCCCP pilot. ARRA funds are being used to sustain jobs, including additional patient navigators, at existing NCCCP hospitals and to expand the entire program to more communities in 2010. An accompanying article looks at community cancer care at three NCCCP centers and how patient navigators are helping cancer patients access the medical, social, and financial services they need throughout treatment and follow up.

NCI Launches Web Site for the Alliance of Glycobiologists

NCI’s Division of Cancer Prevention has launched a Web site for the trans-NIH Alliance of Glycobiologists for Detection of Cancer and Cancer Risk. The alliance is a consortium that is working to reveal the cancer-related dynamics of complex carbohydrates and to develop biomarkers for early cancer detection and risk assessment.

Glycomic biomarkers based on the sugar part of a glycoprotein are a new target area for early cancer detection due to emerging technologies. The Web site details the alliance’s findings, publications, resources, and organizational structure. There is a dedicated page for each of the seven NCI-supported Tumor Glycomics Laboratories, which make up the primary component of the alliance, and links to the alliance’s NIH research partners: the Consortium for Functional Glycomics, funded by the National Institute of General Medical Sciences; the Glycomics and Glycotechnology Resource Centers, supported by the National Center for Research Resources; and NCI’s Early Detection Research Network.

Online Resource on Menthol and Tobacco Now Available from NCI

NCI’s Division of Cancer Control and Population Sciences has launched a new menthol and tobacco Web page that provides background information on the pharmacological properties of menthol and its use in tobacco products as a cigarette additive and flavoring. The page also highlights research on the tobacco industry’s targeted marketing practices to promote the use of menthol tobacco products, and it includes updated information on menthol cigarette use among current smokers by sociodemographic characteristics, based on national data from the 2006–07 Tobacco Use Supplement to the U.S. Census Bureau's Current Population Survey. Other resources, including information on the 2002 First Conference on Menthol Cigarettes, related publications, and links to national and state-level surveys that include questions on menthol, are also available.

Most recently, NCI posted a comprehensive bibliography that includes 343 peer-reviewed research articles related to menthol and tobacco and the final report from the recent Second Conference on Menthol Cigarettes, held in October 2009.

NCI's Reagents Data Portal Features Added Content

Reagents Data Portal banner

NCI recently expanded the Proteomic Reagents and Resources Portal, a community site made available by NCI’s Clinical Proteomic Technologies for Cancer initiative. The portal was created in response to input by the research community on the need for high-quality proteomic reagents and resources.

Added content that is publicly accessible now includes:

  • Data sets to a landmark clinical performance study published in Nature Biotechnology on the reproducibility and transferability of MRM-mass spectrometry across multiple sites
  • Mass spectrometry analytical performance mixtures
  • Standard operating procedures for reagent development and platform usage
  • Computational science (software) tools that enhance instrumentation accuracy and data mining
  • Highly characterized monoclonal antibodies and hybridomas with side-by-side feature comparisons

NCI is transforming clinical proteomics by developing workflows that use metrics and standards with open access to data and reagents, providing researchers with the necessary tools to accurately and quantitatively study cancer etiology at the protein level.