250 Years of Advances Against Cancer - 1700s
John Hill suggests that there may be relationship between the use of tobacco snuff and the development of nasal cancer. His report is the first known to describe an association between exposure to a substance in the environment and the development of cancer.
Percivall Pott identifies a relationship between exposure to chimney soot and the incidence of squamous cell carcinoma of the scrotum among chimney sweeps. His report is the first to clearly link exposure to an environmental carcinogen and the development of cancer.