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Clinical Trials for Supportive and Palliative Care

Clinical trials for supportive and palliative care explore ways to improve the comfort and quality of life of cancer patients and cancer survivors. These trials study ways to help people who are experiencing symptoms related to cancer and its treatment, such as nausea, pain, weight loss, sleep disorders, and depression. Some of these trials also look at nutrition, group therapy, and other interventions to help cancer patients and survivors.

The following links identify supportive and palliative care clinical trials for specific conditions and symptoms that are now accepting patients in the United States. We have also included a link to all supportive and palliative care trials being conducted in the United States. Trial descriptions are from NCI's list of cancer clinical trials.

Management of Physical Symptoms

  • Anemia

    Check for clinical trials about anemia, a common blood disorder in which the number of red blood cells is below normal.

  • Anorexia (Loss of Appetite)

    Check for clinical trials about anorexia, the medical term for an abnormal loss of appetite for food.

  • Fatigue

    Check for clinical trials about fatigue, a condition marked by extreme tiredness and inability to function due to lack of energy.

  • Fever, Sweats, Hot Flashes

    Check for clinical trials about fever, sweats, and hot flashes. A hot flash is a sudden, temporary onset of body warmth, or flushing.

  • Gastrointestinal Complications

    Check for clinical trials about gastrointestinal complications such as constipation, diarrhea, and bowel obstruction.

  • Heart and Circulation Problems (Cardiovascular Complications of Chemotherapy)

    Check for clinical trials about heart and circulation complications of chemotherapy, such as fluid around the heart, difficulty breathing, or swelling of the face, neck, or upper body.

  • Hypercalcemia

    Check for clinical trials about hypercalcemia, the medical term for an abnormally high level of calcium in the blood.

  • Long-Term Effects of Cancer Treatment

    Check for clinical trials about long-term effects of cancer treatment such as physical and mental problems and second cancers.

  • Lymphedema

    Check for clinical trials about lymphedema, a condition in which excess fluid collects in tissue and causes swelling. Such swelling can occur in the arm, leg, or other parts of the body after lymph vessels or lymph nodes in the underarm or groin are removed or treated with radiation.

  • Malignant Pleural Effusion

    Check for clinical trials about malignant pleural effusion, a condition in which cancer causes an abnormal amount of fluid to collect between the thin layers of tissue (pleura) lining the outside of the lung and the wall of the chest cavity. Malignant pleural effusions are most commonly caused by breast cancer, lung cancer, leukemia, or lymphoma.

  • Nausea and Vomiting

    Check for clinical trials about preventing and controlling nausea and vomiting.

  • Nutrition in Cancer Care

    Check for clinical trials about preventing and controlling nutrition problems related to cancer and its treatment.

  • Oral Complications of Cancer and Chemotherapy

    Check for clinical trials about oral complications of cancer and chemotherapy such as infection, bleeding, tooth decay, or dry mouth.

  • Pain

    Check for clinical trials about preventing and controlling pain from cancer or its treatment.

  • Sexuality and Reproductive Issues

    Check for clinical trials about cancer treatment-related sexual function problems and treatment-related reproductive issues such as infertility.

  • Skin Changes Due to Radiation Therapy

    Check for clinical trials about skin changes due to radiation therapy. Skin changes due to radiation therapy include dry or peeling skin, swollen or moist skin.

  • Sleep Disorders

    Check for clinical trials about disorders of the sleep-awake cycle, such as insomnia, anxiety, headaches, itching, night sweats, and treatment-related changes in usual nighttime routine.

Management of Mental and Emotional Symptoms

  • Anxiety

    Check for clinical trials about anxiety, a condition in which feelings of fear, dread, and uneasiness may occur as a reaction to stress.

  • Cognitive/Functional Effects

    Check for clinical trials about cognitive disorders, such as confused mental state or changes in behavior due to cancer or its treatment.

  • Depression

    Check for clinical trials about depression, a mental condition marked by ongoing feelings of sadness, despair, loss of energy, and difficulty dealing with normal daily life.

Management of Spirituality, Quality of Life, and End-of-Life Concerns

  • Quality of Life

    Check for clinical trials about quality of life issues, including trials studying a person's overall enjoyment of life, sense of well-being, and ability to carry out various activities.

  • Spirituality in Cancer Care

    Check for clinical trials about spirituality issues in cancer care, including trials studying a person's sense of peace, purpose, connection to others, and beliefs about the meaning of life.

All Supportive Care Trials

  • Posted: August 8, 2008
  • Updated: February 27, 2010