Related pages Drug Information Summaries 1 Approval Process for New Cancer Treatments 2 Access to Investigational Drugs 3

This page contains brief information about aprepitant and a collection of links to more information about the use of this drug, related research results, and ongoing clinical trials.

US Brand Name(s):		Emend
FDA Approved:		Yes

Aprepitant is approved by the Food and Drug Administration (FDA) to be used together with other drugs to prevent and control nausea and vomiting caused by chemotherapy. It is also used by itself to prevent nausea and vomiting after surgery.

Definition from the NCI Drug Dictionary ⁴ - Detailed scientific definition and other names for this drug.

Clinical Trial Results: Aprepitant Reduces Chemotherapy-Induced Vomiting in Breast Cancer ⁵ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Added to Standard Antinausea Medicines, Aprepitant Improves Results ⁶ - Important clinical trial results for this drug, background information, and how the trial was done.

MedlinePlus Information on Aprepitant ⁷ - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This NLM patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Clinical Trials for Aprepitant ⁸ - Check for trials from NCI's PDQ Cancer Clinical Trials Registry now accepting patients.

Glossary Terms

Treatment with drugs that kill cancer cells.

An agency in the U.S. federal government whose mission is to protect public health by making sure that food, cosmetics, and nutritional supplements are safe to use and truthfully labeled. The Food and Drug Administration also makes sure that drugs, medical devices, and equipment are safe and effective, and that blood for transfusions and transplant tissue are safe. Also called FDA.

A feeling of sickness or discomfort in the stomach that may come with an urge to vomit. Nausea is a side effect of some types of cancer therapy.

To eject some or all of the contents of the stomach through the mouth.