Questions About Cancer? 1-800-4-CANCER

Cancer Drug Information

  • Posted: 10/05/2006
  • Updated: 05/05/2011

Bortezomib

listen 1  (bor-TEH-zoh-mib)

This page contains brief information about bortezomib and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s): VELCADE
FDA Approved: Yes

FDA Approval for Bortezomib 2

Use in Cancer

Bortezomib is approved to treat:

Bortezomib is also being studied in the treatment of other types of cancer.

More About Bortezomib

Definition from the NCI Drug Dictionary 3 - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Bortezomib 4 - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Targeted Cancer Therapies 5 - Information about the use of this drug to treat cancer.

Research Results

Clinical Trial Results: Less-intensive Treatment Regimen Effective against Multiple Myeloma 6 - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Bortezomib Approved for First-Line Treatment of Multiple Myeloma 7 - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Drug Combination Shows Benefit in Relapsed/Refractory Multiple Myeloma 8 - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Bortezomib Delays Progression of Multiple Myeloma Longer than Standard Therapy: Results of the APEX Trial 9 - Important clinical trial results for this drug, background information, and how the trial was done.

Compounds Found in Green Tea Block Bortezomib 10 - Information about the use of this drug to treat cancer.

Clinical Trials Accepting Patients

Find Clinical Trials for Bortezomib 11 - Check for trials from NCI's list of cancer clinical trials now accepting patients.

Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.


Back to TopBack to Top



Glossary Terms

cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
mantle cell lymphoma (MAN-tul sel lim-FOH-muh)
An aggressive (fast-growing) type of B-cell non-Hodgkin lymphoma that usually occurs in middle-aged or older adults. It is marked by small- to medium-size cancer cells that may be in the lymph nodes, spleen, bone marrow, blood, and gastrointestinal system.
multiple myeloma (MUL-tih-pul MY-eh-LOH-muh)
A type of cancer that begins in plasma cells (white blood cells that produce antibodies). Also called Kahler disease, myelomatosis, and plasma cell myeloma.

Table of Links

1http://www.cancer.gov/PublishedContent/Media/CDR/Media/710188.mp3
2http://www.cancer.gov/cancertopics/druginfo/fda-bortezomib
3http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=43560
4http://www.nlm.nih.gov/medlineplus/druginfo/meds/a607007.html
5http://www.cancer.gov/cancertopics/factsheet/Therapy/targeted
6http://www.cancer.gov/clinicaltrials/results/less-intensive-myeloma0910
7http://www.cancer.gov/clinicaltrials/results/bortezomib0908
8http://www.cancer.gov/clinicaltrials/results/myeloma0807
9http://www.cancer.gov/clinicaltrials/results/bortezomib0604
10http://www.cancer.gov/ncicancerbulletin/022409/page3#d
11http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=43560&idtype=1
12http://www.cancer.gov/cancertopics/druginfo/alphalist
13http://www.cancer.gov/cancertopics/druginfo/drug-page-index
14http://www.cancer.gov/clinicaltrials/learningabout/approval-process-for-cancer-
drugs
15http://www.cancer.gov/cancertopics/factsheet/Therapy/investigational-drug-access