Drugs Approved for Colon and Rectal Cancer

This page lists cancer drugs approved by the Food and Drug Administration (FDA) for colon and rectal cancer. The list includes generic and brand names. This page also lists common drug combinations used in colon and rectal cancer. The individual drugs in the combinations are FDA-approved. However, the drug combinations themselves usually are not approved, although they are widely used.

The drug names link to NCI's Cancer Drug Information summaries. There may be drugs used in colon cancer and rectal cancer that are not listed here.

On this page:

• Drugs Approved for Colon Cancer
• Drugs Approved for Rectal Cancer

Drugs Approved for Colon Cancer

Adrucil (Fluorouracil)
¹Avastin (Bevacizumab)
Bevacizumab
²Camptosar (Irinotecan Hydrochloride)
³Capecitabine
⁴Cetuximab ^5
4Efudex (Fluorouracil)
¹Eloxatin (Oxaliplatin)
⁶Erbitux (Cetuximab)
⁵Fluoroplex (Fluorouracil)
Fluorouracil
¹Irinotecan Hydrochloride
³Leucovorin Calcium
⁷Oxaliplatin
⁶Panitumumab
Vectibix (Panitumumab)
⁸Wellcovorin (Leucovorin Calcium)
⁷Xeloda (Capecitabine) ⁴

Drug Combinations Used in Colon Cancer

CAPOX
⁹FOLFIRI 
¹⁰FOLFIRI-BEVACIZUMAB
¹¹FOLFOX
¹²XELOX ¹³

Drugs Approved for Rectal Cancer

Adrucil (Fluorouracil)
¹Avastin (Bevacizumab)
Bevacizumab
²Camptosar (Irinotecan Hydrochloride)
³Cetuximab ^5
4Efudex (Fluorouracil)
¹Erbitux (Cetuximab)
⁵Fluoroplex (Fluorouracil)
Fluorouracil
¹Irinotecan Hydrochloride
³Panitumumab
Vectibix (Panitumumab)
⁸

Drug Combinations Used in Rectal Cancer

CAPOX
⁹FOLFIRI 
¹⁰FOLFIRI-BEVACIZUMAB
¹¹FOLFOX
¹²XELOX ¹³

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