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Ponatinib Hydrochloride

listen  (poh-NA-tih-nib HY-droh-KLOR-ide)

This page contains brief information about ponatinib hydrochloride and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s): Iclusig
FDA Approved: Yes

FDA Approval for Ponatinib Hydrochloride

Use in Cancer

Ponatinib hydrochloride is approved to treat:

For patients with these types of leukemia that do not have the T315I mutation, ponatinib hydrochloride is used when other tyrosine kinase inhibitors cannot be used.

Ponatinib hydrochloride is being studied in the treatment of other types of cancer.

More About Ponatinib Hydrochloride

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Ponatinib Hydrochloride - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Research Results

Clinical Trial Results: New Drug Shows Promise Against Drug-Resistant Leukemias - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trials Accepting Patients

Find Clinical Trials for Ponatinib Hydrochloride - Check for trials from NCI's list of cancer clinical trials now accepting patients.

Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.

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  • Posted: December 26, 2012
  • Updated: March 12, 2014