Tamoxifen Citrate

¹  (tuh-MOK-sih-FEN SIH-trayt)

This page contains brief information about tamoxifen citrate and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s):		Nolvadex
		Novaldex
FDA Approved:		Yes

Use in Cancer

Tamoxifen citrate is approved to treat:

• Breast cancer in women and men.

Tamoxifen citrate is also approved to prevent:

• Breast cancer in women who are at high risk for the disease.

Tamoxifen citrate is also being studied in the treatment of other types of cancer.

Definition from the NCI Drug Dictionary ² - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Tamoxifen Citrate ³ - A lay language summary of important information about this drug that may include the following:

• warnings about this drug,
• what this drug is used for and how it is used,
• what you should tell your doctor before using this drug,
• what you should know about this drug before using it,
• other drugs that may interact with this drug, and
• possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Hormone Therapy for Breast Cancer ⁴ - Information about the use of this drug to prevent and treat cancer.

Commonly Prescribed Antidepressant May Reduce Effectiveness of Tamoxifen in Women with Breast Cancer ⁵ - Information from NCI about this drug.

Targeted Cancer Therapies ⁶ - Information about the use of this drug to treat cancer.

Clinical Trial Results: Exemestane Following Tamoxifen Reduces Breast Cancer Recurrences and Prolongs Survival ⁷ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Study Confirms Letrozole Prevents More Breast Cancer Recurrences Than Tamoxifen ⁸ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Long-Term Data from 20 Trials Confirm Tamoxifen’s Long-Lasting Benefit ⁹ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Tool Weighs Benefits, Risks of Raloxifene or Tamoxifen to Prevent Breast Cancer ¹⁰ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Five Years of Tamoxifen Continues to Benefit Women 15 Years after Treatment ¹¹ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Some Older Women Can Forgo Radiation after Breast Cancer Surgery ¹² - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Zoledronic Acid Improves Early Breast Cancer Treatment ¹³ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Anastrozole, Tamoxifen, and Bone Loss on the ATAC (Arimidex, Tamoxifen Alone or in Combination) Trial ¹⁴ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Studies Affirm Tamoxifen's Long-Term Preventive Benefit ¹⁵ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Anastrozole After Tamoxifen Better for Early Breast Cancer than Tamoxifen Alone ¹⁶ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Advanced Breast Cancer Patients Benefit More from Aromatase Inhibitors than Tamoxifen ¹⁷ - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Anastrozole May Be Better than Tamoxifen at Shrinking Large Breast Tumors Before Surgery ¹⁸ - Important clinical trial results for this drug, background information, and how the trial was done.

Results of the Study of Tamoxifen and Raloxifene (STAR) Released: Osteoporosis Drug Raloxifene Shown to be as Effective as Tamoxifen in Preventing Invasive Breast Cancer ¹⁹ - Information from the NCI Press Office about this drug.

Benefits and Risks of Tamoxifen are Similar in African American and White Women ²⁰ - Information from the NCI Press Office about this drug.

The Study of Tamoxifen and Raloxifene (STAR): Questions and Answers ²¹ - Information from the NCI Press Office about this drug.

Find Clinical Trials for Tamoxifen Citrate ²² - Check for trials from NCI's list of cancer clinical trials now accepting patients.

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