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Trastuzumab

listen  (tras-TOO-zoo-mab)

This page contains brief information about trastuzumab and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s): Herceptin
FDA Approved: Yes

FDA Approval for Trastuzumab

Use in Cancer

Trastuzumab is approved to be used alone or with other drugs to treat:

Trastuzumab is also being studied in the treatment of other types of cancer.

More About Trastuzumab

Definition from the NCI Drug Dictionary - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Trastuzumab - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Targeted Cancer Therapies - Information about the use of this drug to treat cancer.

Biological Therapies for Cancer - Information about the use of this drug to treat cancer.

Adjuvant and Neoadjuvant Therapy for Breast Cancer - Information about the use of this drug to treat cancer.

Research Results

ALTTO (Adjuvant Lapatinib and/or Trastuzumab Treatment Optimisation): Optimising Targeted Therapy for HER2 Breast Cancer - Information about a major NCI-supported clinical trial for this drug.

Clinical Trial Results: For Some Breast Cancers, New Drug May Be Treatment Option - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Two Drugs That Hit One Target Show Efficacy Against Metastastic Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Chemotherapy Less Toxic to the Heart May Be Option for Some Women with HER2-Positive Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trial Results: Trastuzumab after Chemotherapy Is Effective in HER2-Positive Breast Cancer - Important clinical trial results for this drug, background information, and how the trial was done.

Clinical Trials Accepting Patients

Find Clinical Trials for Trastuzumab - Check for trials from NCI's list of cancer clinical trials now accepting patients.

Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.


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  • Posted: October 5, 2006
  • Updated: October 23, 2014