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Cancer Drug Information

  • Posted: 10/10/2006
  • Updated: 11/04/2011

Vorinostat

listen 1  (vor-IN-oh-stat)

This page contains brief information about vorinostat and a collection of links to more information about the use of this drug, research results, and ongoing clinical trials.

US Brand Name(s): Zolinza
FDA Approved: Yes

FDA Approval for Vorinostat 2

Use in Cancer

Vorinostat is approved to treat:

Vorinostat is also being studied in the treatment of other types of cancer.

More About Vorinostat

Definition from the NCI Drug Dictionary 3 - Detailed scientific definition and other names for this drug.

MedlinePlus Information on Vorinostat 4 - A lay language summary of important information about this drug that may include the following:

  • warnings about this drug,
  • what this drug is used for and how it is used,
  • what you should tell your doctor before using this drug,
  • what you should know about this drug before using it,
  • other drugs that may interact with this drug, and
  • possible side effects.

Drugs are often studied to find out if they can help treat or prevent conditions other than the ones they are approved for. This patient information sheet applies only to approved uses of the drug. However, much of the information may also apply to unapproved uses that are being studied.

Targeted Cancer Therapies 5 - Information about the use of this drug to treat cancer.

Clinical Trials Accepting Patients

Find Clinical Trials for Vorinostat 6 - Check for trials from NCI's list of cancer clinical trials now accepting patients.

Important: The drug information on this page is meant to be educational. It is not a substitute for medical advice. The information may not cover all possible uses, actions, interactions, or side effects of this drug, or precautions to be taken while using it. Please see your health care professional for more information about your specific medical condition and the use of this drug.


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Glossary Terms

cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
chemotherapy (KEE-moh-THAYR-uh-pee)
Treatment with drugs that kill cancer cells.
cutaneous T-cell lymphoma (kyoo-TAY-nee-us … lim-FOH-muh)
Any of a group of T-cell non-Hodgkin lymphomas that begins in the skin as an itchy, red rash that can thicken or form a tumor. The most common types are mycosis fungoides and Sézary syndrome.
recurrent cancer (ree-KER-ent KAN-ser)
Cancer that has recurred (come back), usually after a period of time during which the cancer could not be detected. The cancer may come back to the same place as the original (primary) tumor or to another place in the body. Also called recurrence.

Table of Links

1http://www.cancer.gov/PublishedContent/Media/CDR/Media/703924.mp3
2http://www.cancer.gov/cancertopics/druginfo/fda-vorinostat
3http://www.cancer.gov/Templates/drugdictionary.aspx?CdrID=37944
4http://www.nlm.nih.gov/medlineplus/druginfo/meds/a607050.html
5http://www.cancer.gov/cancertopics/factsheet/Therapy/targeted
6http://www.cancer.gov/Search/ClinicalTrialsLink.aspx?id=37944&idtype=1
7http://www.cancer.gov/cancertopics/druginfo/alphalist
8http://www.cancer.gov/cancertopics/druginfo/drug-page-index
9http://www.cancer.gov/clinicaltrials/learningabout/approval-process-for-cancer-
drugs
10http://www.cancer.gov/cancertopics/factsheet/Therapy/investigational-drug-access