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Genetics of Colorectal Cancer (PDQ®)

  • Updated: 10/10/2014

Table 6. Spigelman Classification

Points Polyp Number Polyp Size (mm) Histology Dysplasia 
Stage I, 1–4 points; Stage II, 5–6 points; Stage III, 7–8 points; Stage IV, 9–12 points [88]
11–41–4TubularMild
25–204–10TubulovillousModerate
3>20>10VillousSevere

References

  1. Spigelman AD, Williams CB, Talbot IC, et al.: Upper gastrointestinal cancer in patients with familial adenomatous polyposis. Lancet 2 (8666): 783-5, 1989.  [PUBMED Abstract]