In English | En español
Questions About Cancer? 1-800-4-CANCER

Genetics of Endocrine and Neuroendocrine Neoplasias (PDQ®)

  • Updated: 05/08/2014

Table 3. Percentage of Patients with Clinical Features of MEN2 by Subtype

Subtype  Medullary Thyroid Carcinoma (%)a Pheochromocytoma (%)a Parathyroid Disease (%)a 
MEN2A955015–30
FMTC~10000
MEN2B10050Uncommon

FMTC = familial medullary thyroid carcinoma; MEN2 = multiple endocrine neoplasia type 2.
aPercentages based on observations in referral populations.[5-9]

References

  1. Eng C: Seminars in medicine of the Beth Israel Hospital, Boston. The RET proto-oncogene in multiple endocrine neoplasia type 2 and Hirschsprung's disease. N Engl J Med 335 (13): 943-51, 1996.  [PUBMED Abstract]

  2. Gagel RF, Tashjian AH Jr, Cummings T, et al.: The clinical outcome of prospective screening for multiple endocrine neoplasia type 2a. An 18-year experience. N Engl J Med 318 (8): 478-84, 1988.  [PUBMED Abstract]