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Endometrial Cancer Prevention (PDQ®)
Patient VersionHealth Professional VersionLast Modified: 05/02/2008
Average Annual Rates of Invasive and In Situ Endometrial Cancer

  Placebo   Tamoxifen  
Type of Event No. of Events Rate per 1,000 Women No. of Events Rate per 1,000 Women Risk Ratio 95% Confidence Interval
Invasive Cancer 15 0.91 36 2.30 2.53 1.35–4.97
Age ≤49 8 1.09 9 1.32 1.21 0.41–3.60
Age ≥50 7 0.76 27 3.05 4.01 1.70–10.90
In Situ Cancer 3 0.18 1 0.06 0.35 0.01–4.38

No. = number.
Table adapted from Fisher et al. Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. Journal of the National Cancer Institute 90 (18): 1371–1388, 1998.


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