Screening Test Administered		PSA	DRE	PSA or DRE
Number of Men Receiving Test		34,233	34,115	34,224
Positive Test (%): DRE Suspicious for Cancer; PSA >4 ng/mL		2,717 (7.9)	2,482 (7.3)	4,801 (14.1)
Biopsies (% of positives)		1,112 (40.9)	639 (25.7)	1,510 (31.5)
Prostate Cancer (% of biopsies)		489 (44.0)	219 (34.3)	556 (36.8)
Prostate Cancer (% of positives)		489 (18.0)	219 (8.8)	556 (11.6)

DRE = digital rectal exam; PSA = prostate-specific antigen.

aProstate cancer diagnosis rates increased as PSA concentrations increased among both DRE-positive and DRE-negative men.[44]

References

44. Andriole GL, Levin DL, Crawford ED, et al.: Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized trial. J Natl Cancer Inst 97 (6): 433-8, 2005.  [PUBMED Abstract]