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Hypercalcemia (PDQ®)     
Last Modified: 06/30/2009
Health Professional Version
Incidence by Cancer Type

Hypercalcemia occurs more frequently in some malignancies (e.g., squamous cell cancers of the lung, head, neck, and esophagus) than in others. Within each disease type, the incidence of hypercalcemia varies greatly in reported series. The frequency of hypercalcemia in some of the commonly involved neoplastic disorders is shown in Table 1.

Table 1. Incidence of Hypercalcemia by Tumor Typea
Tumor Type  Percentage of Patients Who Develop Hypercalcemia 
aAdapted from Lang-Kummer.[1]
Lung 27.3
Breast 25.7
Multiple myeloma 7.3
Head and neck 6.9
Unknown primary 4.7
Lymphoma/leukemia 4.3
Renal 4.3
Gastrointestinal 4.1

References

  1. Lang-Kummer J: Hypercalcemia. In: Groenwald SL, Goodman M, Frogge MH, et al., eds.: Cancer Nursing: Principles and Practice. 4th ed. Sudbury, Mass: Jones and Bartlett Publishers, 1997, pp 684-701. 



Table of Links

1http://www.cancer.gov/cancertopics/pdq/supportivecare/hypercalcemia/HealthProfe
ssional/Table1