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Smoking Cessation and Continued Risk in Cancer Patients (PDQ®)

Patient Version
Last Modified: 03/20/2012

Poorer Treatment Response in Cancer Patients

If cancer is diagnosed in a smoker, studies have found that quitting smoking will still be helpful. Even recent quitters are more likely to recover from cancer than smoking patients are. Continuing to smoke may decrease the effectiveness of treatment and may worsen treatment side effects. For example, patients who have received radiation therapy for laryngeal cancer are less likely to regain satisfactory voice quality if they continue to smoke. Also, wound healing following surgery will be more difficult if one continues to smoke. Studies have found that prostate cancer patients who keep smoking have an increased risk of earlier recurrence and death from prostate cancer. Prostate cancer patients who quit smoking for 10 years or longer, however, have about the same risk of death as nonsmokers.



Glossary Terms

cancer (KAN-ser)
A term for diseases in which abnormal cells divide without control and can invade nearby tissues. Cancer cells can also spread to other parts of the body through the blood and lymph systems. There are several main types of cancer. Carcinoma is a cancer that begins in the skin or in tissues that line or cover internal organs. Sarcoma is a cancer that begins in bone, cartilage, fat, muscle, blood vessels, or other connective or supportive tissue. Leukemia is a cancer that starts in blood-forming tissue such as the bone marrow, and causes large numbers of abnormal blood cells to be produced and enter the blood. Lymphoma and multiple myeloma are cancers that begin in the cells of the immune system. Central nervous system cancers are cancers that begin in the tissues of the brain and spinal cord. Also called malignancy.
diagnosis (DY-ug-NOH-sis)
The process of identifying a disease, such as cancer, from its signs and symptoms.
laryngeal (luh-RIN-jee-ul)
Having to do with the larynx.
prostate cancer (PROS-tayt KAN-ser)
Cancer that forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the rectum). Prostate cancer usually occurs in older men.
radiation therapy (RAY-dee-AY-shun THAYR-uh-pee)
The use of high-energy radiation from x-rays, gamma rays, neutrons, protons, and other sources to kill cancer cells and shrink tumors. Radiation may come from a machine outside the body (external-beam radiation therapy), or it may come from radioactive material placed in the body near cancer cells (internal radiation therapy). Systemic radiation therapy uses a radioactive substance, such as a radiolabeled monoclonal antibody, that travels in the blood to tissues throughout the body. Also called irradiation and radiotherapy.
recover (ree-KUH-ver)
To become well and healthy again.
recurrence (ree-KER-ents)
Cancer that has recurred (come back), usually after a period of time during which the cancer could not be detected. The cancer may come back to the same place as the original (primary) tumor or to another place in the body. Also called recurrent cancer.
side effect (side eh-FEKT)
A problem that occurs when treatment affects healthy tissues or organs. Some common side effects of cancer treatment are fatigue, pain, nausea, vomiting, decreased blood cell counts, hair loss, and mouth sores.
surgery (SER-juh-ree)
A procedure to remove or repair a part of the body or to find out whether disease is present. An operation.
wound (woond)
A break in the skin or other body tissues caused by injury or surgical incision (cut).