Soft Tissue Sarcoma Histologic Subtype	Agent Under Study
Myxoid liposarcoma	Trabectedin[11]
Alveolar soft part sarcoma	Sunitinib[12,13]
Desmoplastic small round cell tumor
Angiosarcoma	Sorafenib[14]
Perivascular epithelioid cell tumor (PEcoma)	Mammalian target of rapamycin (mTOR)-inhibitors[15,16]
Malignant peripheral nerve sheath tumor
Synovial sarcoma	Pazopanib[17]
Leiomyosarcoma

References

11. Grosso F, Jones RL, Demetri GD, et al.: Efficacy of trabectedin (ecteinascidin-743) in advanced pretreated myxoid liposarcomas: a retrospective study. Lancet Oncol 8 (7): 595-602, 2007.  [PUBMED Abstract]
    
    
12. Stacchiotti S, Tamborini E, Marrari A, et al.: Response to sunitinib malate in advanced alveolar soft part sarcoma. Clin Cancer Res 15 (3): 1096-104, 2009.  [PUBMED Abstract]
    
    
13. George S, Merriam P, Maki RG, et al.: Multicenter phase II trial of sunitinib in the treatment of nongastrointestinal stromal tumor sarcomas. J Clin Oncol 27 (19): 3154-60, 2009.  [PUBMED Abstract]
    
    
14. Maki RG, D'Adamo DR, Keohan ML, et al.: Phase II study of sorafenib in patients with metastatic or recurrent sarcomas. J Clin Oncol 27 (19): 3133-40, 2009.  [PUBMED Abstract]
    
    
15. Davies DM, Johnson SR, Tattersfield AE, et al.: Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis. N Engl J Med 358 (2): 200-3, 2008.  [PUBMED Abstract]
    
    
16. Johansson G, Mahller YY, Collins MH, et al.: Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Mol Cancer Ther 7 (5): 1237-45, 2008.  [PUBMED Abstract]
    
    
17. Sleijfer S, Ray-Coquard I, Papai Z, et al.: Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European organisation for research and treatment of cancer-soft tissue and bone sarcoma group (EORTC study 62043). J Clin Oncol 27 (19): 3126-32, 2009.  [PUBMED Abstract]