In English | En español
Questions About Cancer? 1-800-4-CANCER

Childhood Central Nervous System Embryonal Tumors Treatment (PDQ®)

  • Posted: 02/13/2008
  • Updated: 10/29/2014

Table 3. Standard Treatment Options for Childhood Central Nervous System (CNS) Embryonal Tumors

Stage and/or Histopathologic Classification Standard Treatment Options 
Newly diagnosed childhood medulloblastoma:
Children older than 3 years with average-risk medulloblastomaSurgery
Adjuvant therapy (radiation therapy and chemotherapy)
Children older than 3 years with high-risk medulloblastomaSurgery
Adjuvant therapy (radiation therapy and chemotherapy)
Children aged 3 years and youngerSurgery
Adjuvant chemotherapy
Newly diagnosed CNS primitive neuroectodermal tumor:
Children older than 3 yearsSurgery
Adjuvant therapy (radiation therapy and chemotherapy)
Children aged 3 years and youngerSimilar to children aged 3 years and younger with medulloblastoma (surgery and adjuvant chemotherapy)
Newly diagnosed medulloepithelioma and ependymoblastomaSame as for children with high-risk medulloblastoma (surgery and adjuvant therapy) and children aged 3 years and younger with other embryonal tumors
Newly diagnosed pineoblastoma:
Children older than 3 yearsSurgery
Adjuvant therapy (radiation therapy and chemotherapy)
Children aged 3 years and youngerBiopsy (for diagnosis)
Chemotherapy
High-dose, marrow-ablative chemotherapy with autologous bone marrow rescue or peripheral stem cell rescue
Recurrent childhood CNS embryonal tumors (treatment options not considered standard)Surgery
Radiation therapy
Chemotherapy
High-dose chemotherapy with stem cell rescue