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Table 4. Comparison of Adult BEP and Pediatric PEB and JEB Chemotherapy Dosing Schedulesa

Regimen Bleomycin Etoposide Cisplatin Carboplatin 
Adult BEP (every 21 days)b [15,18]30 units/m2, days 1, 8, 15100mg/m2, days 1–520 mg/m2, days 1–5
Pediatric PEB (every 21 days) [1,2]15 units/m², day 1100 mg/m², days 1–520 mg/m², days 1–5
Pediatric JEB (every 21–28 days) [3]15 units/m², day 3120 mg/m², days 1–3600 mg/m² or GFR-based dosing, day 2

BEP = bleomycin, etoposide, and cisplatin; GFR = glomerular filtration rate; JEB = carboplatin, etoposide, and bleomycin; PEB = cisplatin, etoposide, and bleomycin.
aAdult doses of PEB and JEB chemotherapy are different from pediatric doses.
bThe adult BEP regimen is provided here for comparison only; BEP is not used in the treatment of children.


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