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Table 1. Primary Tumor (T)a

aReprinted with permission from AJCC: Gallbladder. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 211-7.
TXPrimary tumor cannot be assessed.
T0No evidence of primary tumor.
TisCarcinoma in situ.
T1Tumor invades lamina propria or muscular layer.
T1aTumor invades lamina propria.
T1bTumor invades muscular layer.
T2Tumor invades perimuscular connective tissue; no extension beyond serosa or into liver.
T3Tumor perforates the serosa (visceral peritoneum) and/or directly invades the liver and/or one other adjacent organ or structure, such as the stomach, duodenum, colon, pancreas, omentum, or extrahepatic bile ducts.
T4Tumor invades main portal vein or hepatic artery or invades at least two extrahepatic organs or structures.