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Table 6. Anatomic Stage/Prognostic Groupsa

Group T N M PSA ng/ml Gleason 
IT1a–cN0M0PSA <10Gleason ≤6
T2aN0M0PSA <10Gleason ≤6
T1–2aN0M0PSA XGleason X
IIAT1a–cN0M0PSA <20Gleason 7
T1a–cN0M0PSA ≥10 <20Gleason ≤6
T2aN0M0PSA <20Gleason ≤7
T2bN0M0PSA <20Gleason ≤7
T2bN0M0PSA XGleason X
IIBT2cN0M0Any PSAAny Gleason
T1–2N0M0PSA ≥20Any Gleason
T1–2N0M0Any PSAGleason ≥8
IIIT3a–bN0M0Any PSAAny Gleason
IVT4N0M0Any PSAAny Gleason
Any TN1M0Any PSAAny Gleason
Any TAny NM1Any PSAAny Gleason

T = Primary tumor; N = Regional lymph nodes; M = Distant metastasis; PSA = Prostate-specific antigen.
Reprinted with permission from AJCC: Prostate. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 457-68.
aWhen either PSA or Gleason is not available, grouping should be determined by T stage and/or either PSA or Gleason as available.