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Table 3. Distant Metastasis (M)a

aReprinted with permission from AJCC: Colon and rectum. In: Edge SB, Byrd DR, Compton CC, et al., eds.: AJCC Cancer Staging Manual. 7th ed. New York, NY: Springer, 2010, pp 143-164.
M0No distant metastasis.
M1Distant metastasis.
M1aMetastasis confined to 1organ or site (e.g., liver, lung, ovary, nonregional node).
M1bMetastases in >1 organ/site or the peritoneum.