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Vulvar Cancer Treatment (PDQ®)

  • Updated: 03/12/2014

Table 1. Carcinoma of the Vulvaa

Stage ITumor confined to the vulva.
IALesions ≤2 cm in size, confined to the vulva or perineum and with stromal invasion ≤1.0 mmb, no nodal metastasis.
IBLesions >2 cm in size or with stromal invasion >1.0 mmb, confined to the vulva or perineum, with negative nodes.
Stage IITumor of any size with extension to adjacent perineal structures (1/3 lower urethra, 1/3 lower vagina, anus) with negative nodes.
Stage IIITumor of any size with or without extension to adjacent perineal structures (1/3 lower urethra, 1/3 lower vagina, anus) with positive inguino-femoral lymph nodes.
IIIA(i) With 1 lymph node metastasis (≥5 mm), or
(ii) 1–2 lymph node metastasis(es) (<5 mm).
IIIB(i) With 2 or more lymph node metastases (≥5 mm), or
(ii) 3 or more lymph node metastases (<5 mm).
IIICWith positive nodes with extracapsular spread.
Stage IVTumor invades other regional (2/3 upper urethra, 2/3 upper vagina), or distant structures.
IVATumor invades any of the following:
(i) upper urethral and/or vaginal mucosa, bladder mucosa, rectal mucosa, or fixed to pelvic bone, or
(ii) fixed or ulcerated inguino-femoral lymph nodes.
IVBAny distant metastasis including pelvic lymph nodes.

aAdapted from FIGO Committee on Gynecologic Oncology.[2]
bThe depth of invasion is defined as the measurement of the tumor from the epithelial-stromal junction of the adjacent most superficial dermal papilla to the deepest point of invasion.

References

  1. Pecorelli S: Revised FIGO staging for carcinoma of the vulva, cervix, and endometrium. Int J Gynaecol Obstet 105 (2): 103-4, 2009.  [PUBMED Abstract]