In English | En español
Questions About Cancer? 1-800-4-CANCER

Wilms Tumor and Other Childhood Kidney Tumors Treatment (PDQ®)

  • Updated: 08/15/2014

Table 1. Syndromes and Conditions Associated With Wilms Tumor

Syndrome/Condition  Gene Overgrowth Phenotype  Nonovergrowth Phenotype 
WAGR = Wilms tumor, aniridia, genitourinary anomaly, and mental retardation.
9q22.3 microdeletion syndrome9q22.3X
Beckwith-Wiedemann syndromeWT2 X
Isolated hemihypertrophyX
Perlman syndromeDIS3L2 X
Simpson-Golabi-Behemel syndromeGPC3 X
Sotos syndromeNSD1 X
Bloom syndromeBLM X
Denys-Drash syndromeWT1 X
Familial Wilms tumorFWT1 X
FWT2
Frasier syndromeWT1 X
Genitourinary anomaliesWT1 X
Fanconi anemia with biallelic mutations in BRCA2 (FANCD1) or PALB2 (FANCN)BRCA2 X
PALB2
Li-Fraumeni syndromeTP53 X
CHEK2
Sporadic aniridiaWT1 X
Trisomy 18X
WAGR syndromeWT1 X