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Breast Cancer: Treatment

Information Summaries from PDQ

Clinical Trials

  • Find Clinical Trials to Treat Breast Cancer

    Check for breast cancer treatment trials from NCI's list of cancer clinical trials now accepting patients. The list of clinical trials can be refined by location, stage of disease, drug, and other features.

  • The ALTTO Breast Cancer Trial

    A collection of material about the Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation, or ALTTO, study that will compare the targeted agents lapatinib and trastuzumab alone, in sequence, or in combination as adjuvant therapy for HER2-positive breast cancer.

  • The TAILORx Breast Cancer Trial

    A collection of material about the Trial Assigning IndividuaLized Options for Treatment (Rx), or TAILORx, which will examine whether a molecular test can assign women with early-stage breast cancer to the most appropriate and effective treatment.

Research Findings

Types of Breast Cancer Therapies

  • Surgery Choices for Women With DCIS or Breast Cancer

    Women diagnosed with DCIS or breast cancer may face a decision about which surgery to have. The choices of breast-sparing surgery, mastectomy, or mastectomy with reconstruction are explained and compared.

  • Sentinel Lymph Node Biopsy

    A fact sheet that describes the sentinel lymph node biopsy (SLNB) procedure, its use in determining the extent, or stage, of cancer in the body, and the results of research on the use of SLNB in breast cancer and melanoma.

  • Breast Reconstruction After Mastectomy

    A fact sheet that describes breast reconstruction after mastectomy, including surgical options, follow-up care, and breast cancer screening after reconstruction.

  • Drugs Approved for Breast Cancer

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for breast cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  • Adjuvant and Neoadjuvant Therapy for Breast Cancer

    A fact sheet that explains different types of adjuvant therapy (treatment given after primary therapy to increase the chance of long-term survival) and neoadjuvant therapy (treatment given before primary therapy). Discusses side effects, risks, and benefits of adjuvant and neoadjuvant therapy for breast cancer.

  • Hormone Therapy for Breast Cancer

    A fact sheet that describes hormone therapy (including antiestrogens, LH-RH agonists, aromatase inhibitors, and SERMs) and its role in preventing and treating breast cancer. Includes information about possible side effects.

  • NIH Report on the Diagnosis and Management of Ductal Carcinoma In Situ

    An NIH panel urges further research to determine which ductal carcinoma in situ (DCIS) patients may be candidates for less invasive therapy.

  • Inflammatory Breast Cancer

    A fact sheet about the diagnosis and treatment of inflammatory breast cancer (IBC), an uncommon type of cancer in which the breast becomes red, swollen, and warm.

  • Paget Disease of the Breast

    A fact sheet about Paget disease of the breast, a rare type of cancer that is sometimes called Paget disease of the nipple or mammary Paget disease.

Related Treatment Information

  • Angiogenesis Inhibitors

    A fact sheet that describes the process of eliminating the blood supply to tumors. Lists the cancers in which this approach is being tested.

  • Biological Therapies for Cancer

    A fact sheet that provides an overview of how the immune system functions and describes the actions of biological therapies, such as monoclonal antibodies, cytokines, therapeutic vaccines, the bacterium bacillus Calmet-Guérin, cancer-killing viruses, gene therapy, and adoptive T-cell transfer.

  • Radiation Therapy for Cancer

    A fact sheet that defines the different types of radiation therapy and discusses scientific advances that improve the effectiveness of this treatment.

  • Targeted Cancer Therapies

    A fact sheet that describes targeted cancer therapies, which are drugs that interfere with specific molecules involved in cancer cell growth and survival.

  • Cancer Vaccines

    A fact sheet that discusses cancer vaccines. Explains how they work, how they are made, and describes research related to their use.