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Understanding Cancer Series

  • Posted: 01/28/2005
  • Reviewed: 09/01/2006

Slide 14

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Meiosis and Germline Mutations

Unlike other human body cells, maturing germ cells, like ova or sperm, must cut their chromosome number from 46 to 23, from 2N to N. They do this through two specialized cell divisions in a process called meiosis. After meiosis is complete, each germ cell has only one-half of the 44 original body chromosomes (or autosomes) plus either an X or a Y sex chromosome.

Meiosis and Germline Mutations