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Understanding Cancer Series

  • Posted: 01/28/2005
  • Reviewed: 09/01/2006

Slide 39

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Mutations in Cancer Susceptibility Genes: BRCA2

Here is an example of the mutations seen in the BRCA2 breast cancer susceptibility gene.

Inheriting these mutated alleles greatly increases a person's lifetime risk for developing cancer. This may explain why cancers linked to germline mutations in susceptibility genes often occur at an earlier age and in multiple sites.

Mutations in Cancer Susceptibility Genes: <i>BRCA2</i>