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Understanding Cancer Series

  • Posted: 01/28/2005
  • Reviewed: 09/01/2006

Slide 40


Autosomal Dominant Inheritance

Most hereditary cancer syndromes are inherited in autosomal dominant fashion.

Dominant inheritance occurs when only one copy of an allele is required for a particular trait to be expressed (phenotype). In autosomal dominant inheritance, multiple generations express the traits, with no skipped generations (assuming complete penetrance).

Autosomal Dominant Inheritance