In English | En español
Questions About Cancer? 1-800-4-CANCER

Understanding Cancer Series

< Back to Main
  • Posted: 01/28/2005
  • Reviewed: 09/01/2006

Page Options

  • Print This Page
  • Print This Document
  • View Entire Document
  • Email This Document
  • View/Print PDF
  • View/Print PowerPoint

Slide 52

:

Mutations in Tumor Suppressor Genes

< Previous SectionNext Section >

Both copies of a tumor suppressor gene must be lost or mutated for cancer to occur. A person who carries a germline mutation in a tumor suppressor gene has only one functional copy of the gene in all cells. For this person, loss or mutation of the second copy of the gene in any of these cells can lead to cancer.

Mutations in Tumor Suppressor Genes