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  • Posted: 12/29/2009

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Slide 9

:

Genetic Variation in Coding Regions

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The remaining SNPs occur in coding regions. They may alter the protein made by that coding region, which in turn could influence a person's health.

Some of the variations that occur in the coding and regulatory regions of genes simply contribute to the normal variation observed among people. They can, for example, change the way a person looks. Some people have blue eyes, others brown; some are tall, others short.

Other variations in coding regions are harmless because they occur in regions of a gene that do not affect the function of the protein made.

Graphic shows that even when the little flags representing single nucleotide polymorphisms occur in coding regions, some change can occur that is still not harmful, such as differences in a person's height.