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Understanding Cancer Series

  • Posted: 01/28/2005
  • Reviewed: 09/01/2006

Slide 24

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SNPs in Coding Regions No Changes in Protein

When a SNP occurs within a coding region, it is possible that there is no effect. For example, when the DNA sequence GAC becomes GAG, the codon in the mRNA changes from CUG to CUC. Since both codons stand for the same amino acid leucine, there is no change in the protein. The change in the DNA is called a silent change.

SNPs in Coding Regions No Changes in Protein