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Understanding Cancer Series

  • Posted: 01/28/2005
  • Reviewed: 09/01/2006

Slide 25

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SNPs in Coding Regions - Subtle, Harmless Changes in Protein

There are also SNPs within coding regions that lead to very subtle changes in proteins. For example, if a SNP causes the codon GAU to change to GAG, the amino acid changes from aspartic acid to glutamic acid. These amino acids have very similar chemical properties, but glutamic acid is just a little bigger. If the SNP causes a change in a part of the protein that is not important to its function, the result may be very subtle or totally harmless. The cell continues to function normally.

SNPs in Coding Regions - Subtle, Harmless Changes in Protein