Can Genome-Wide Profiles Predict Cancer Risk?
Not yet. Cancer is a complex disease that is driven by genetic, lifestyle, and environmental factors. Furthermore, each individual and each tumor are unique. Thus, it has proven difficult to identify a predictive genomic profile that is valid for multiple populations. Claims that a particular genomic profile can predict cancer risk should be interpreted with caution. It is likely that genomic profiles will need to be used in conjunction with other genetic and clinical information to accurately assess a person's cancer risk.