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Last Modified: 11/24/2009     First Published: 7/1/2002  
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Phase III Randomized Study of Adjuvant Cyclophosphamide and Doxorubicin Versus Single-Agent Paclitaxel in Women With Operable Breast Cancer and 0-3 Positive Axillary Lymph Nodes

Alternate Title
Basic Trial Information
Objectives
Entry Criteria
Expected Enrollment
Outcomes
Outline
Trial Contact Information
Related Information
Registry Information

Alternate Title

Cyclophosphamide and Doxorubicin or Paclitaxel in Treating Women With Breast Cancer

Basic Trial Information

PhaseTypeStatusAgeSponsorProtocol IDs
Phase IIITreatmentActive18 and overNCICALGB-40101
NCT00041119

Special Category: CTSU trial, NCI Web site featured trial

Objectives

Primary

  1. Compare the disease-free survival of women with operable breast cancer and 0-3 positive axillary lymph nodes treated with two different schedules (4 vs 6 courses) of adjuvant cyclophosphamide and doxorubicin vs paclitaxel. (Arms II and IV closed to accrual as of 1/30/2008)
  2. Compare the disease-free survival of patients treated with these regimens.

Secondary

  1. Compare overall survival, local control, and time to distant metastasis in patients treated with these regimens.
  2. Compare the toxic effects of these regimens in these patients.
  3. Compare the effect of these regimens on the induction of menopause in premenopausal patients.
  4. Determine the discrepancy of myelosuppression in patients with MDR1 haplotypes on the CA treatment arm.
  5. Compare the disease-free survival of patients with MDR1 haplotypes treated with these regimens.
  6. Correlate CYP3A5, CYP2C8, and CYP2B6 polymorphisms with disease-free survival and toxicity in patients treated with these regimens.

Entry Criteria

Disease Characteristics:

  • Histologically confirmed invasive carcinoma of the breast with 0-3 positive axillary lymph nodes
    • Meets 1 of the following criteria for node-negative disease:
      • Negative sentinel lymph node biopsy
      • At least 6 negative axillary lymph nodes removed and determined to be negative by axillary dissection

    • Meets 1 of the following criteria for node-positive disease (1-3 positive axillary lymph nodes):
      • At least 1 positive lymph node by sentinel lymph node biopsy AND at least 6 axillary lymph nodes removed by axillary dissection; of all the nodes removed from both the sentinel lymph node biopsy and the axillary dissection, 1-3 must be positive
      • At least 6 lymph nodes removed by axillary dissection; 1-3 nodes from the axillary dissection must be positive

  • "High-risk" disease that warrants chemotherapy (ultimately determined by the treating physician)

  • Modified radical mastectomy or lumpectomy within the past 84 days required
    • Negative tumor margins for invasive cancer and ductal carcinoma in situ (DCIS)
    • Lobular carcinoma in situ (LCIS) at the margin allowed

  • Multicentric disease allowed provided margins and axillary nodes are negative after resection

  • Bilateral synchronous disease allowed

  • Invasive cancer on one side and DCIS or LCIS on the contralateral side is allowed provided all other eligibility criteria are met

  • No locally advanced, inflammatory, or metastatic breast cancer

  • No dermal lymphatics involvement, even if there are no clinical signs of inflammatory cancer

  • HER2/neu positive, negative, or unknown

  • Hormone receptor status:
    • Any estrogen and/or progesterone receptor status

Prior/Concurrent Therapy:

Biologic therapy:

  • No prior trastuzumab (Herceptin®) for this malignancy

Chemotherapy:

  • See Disease Characteristics
  • No prior chemotherapy for this malignancy
  • No other concurrent chemotherapy

Endocrine therapy:

  • No prior hormonal therapy for this malignancy except tamoxifen given for up to 4 weeks
  • Prior tamoxifen or other selective estrogen receptor modulators (SERMs) for prevention or other indications (e.g., osteoporosis) allowed
  • No concurrent exogenous hormonal therapy (including oral contraceptives, postmenopausal hormone replacement therapy, or raloxifene) except:
    • Steroids for adrenal failure
    • Hormonal agents for nondisease-related conditions (e.g., insulin for diabetes or synthroid for hypothyroidism)
    • Intermittent dexamethasone as an antiemetic and premedication for paclitaxel
  • No concurrent tamoxifen or other SERMs

Surgery:

  • See Disease Characteristics

Other:

  • No concurrent dexrazoxane
  • No concurrent raloxifene
  • Concurrent bisphosphonates for osteoporosis allowed
  • Concurrent trastuzumab (Herceptin®) allowed for patients with HER2-positive disease
  • Concurrent enrollment on adjuvant bisphosphonate studies allowed
  • Concurrent enrollment on adjuvant hormonal studies allowed provided hormonal therapy does not commence until completion of study chemotherapy

Patient Characteristics:

Age:

  • 18 and over

Sex:

  • Female

Menopausal status:

  • Premenopausal or postmenopausal

Performance status:

  • CTC 0-1

Life expectancy:

  • Not specified

Hematopoietic:

  • Absolute neutrophil count at least 1,000/mm3
  • Platelet count at least 100,000/mm3

Hepatic:

  • Bilirubin no greater than 1.5 times upper limit of normal

Renal:

  • Creatinine no greater than 2.0 mg/dL

Cardiovascular:

  • No active congestive heart failure
  • No myocardial infarction within the past 6 months

Other:

  • Not pregnant or nursing
  • Fertile patients must use effective nonhormonal contraception during and for at least 2 months after study participation
  • No other malignancy within the past 5 years except curatively treated basal cell or squamous cell skin cancer or carcinoma in situ of the cervix

Expected Enrollment

4646

A total of 4,646 patients will be accrued for this study within 29 months.

Outcomes

Primary Outcome(s)

Disease-free survival

Secondary Outcome(s)

Overall survival
Toxicity
Myelosuppression in patients with MDR1 haplotypes
CYP3A5, CYP2C8, and CYP2B6 polymorphisms

Outline

This is a randomized study. Patients are stratified according to menopausal status (premenopausal vs postmenopausal), estrogen receptor (ER)/progesterone receptor (PR) status (ER and/or PR positive or unknown vs ER and PR negative), and HER2/neu status (negative vs unknown vs positive [by immunohistochemistry 3+ staining or gene amplification by fluorescence in situ hybridization]). Patients are randomized to 1 of 4 treatment arms (arms II and IV closed to accrual as of 1/30/2008).

  • Arm I: Patients receive doxorubicin IV and cyclophosphamide IV on day 1. Treatment repeats every 14 days for 4 courses.

  • Arm II (closed to accrual as of 1/30/2008): Patients receive doxorubicin and cyclophosphamide as in arm I. Treatment repeats every 14 days for 6 courses.

  • Arm III: Patients receive paclitaxel IV over 1 hour on day 1. Treatment repeats every 14 days for 4 courses.

  • Arm IV (closed to accrual as of 1/30/2008): Patients receive paclitaxel as in arm III. Treatment repeats every 14 days for 6 courses.

Treatment in all arms continues in the absence of disease progression or unacceptable toxicity.

Lumpectomy patients must then undergo radiotherapy. Mastectomy patients undergo radiotherapy at the discretion of the treating physician.

Patients are followed every 6 months for 2 years and then annually for 15 years.

Trial Contact Information

Trial Lead Organizations

Cancer and Leukemia Group B

Lawrence Shulman, MD, Protocol chair
Ph: 617-632-2277; 866-790-4500
Email: Lawrence_Shulman@dfci.harvard.edu

Trial Sites

U.S.A.
Alabama
  Anniston
 Regional Medical Center
 Pramod Vadlamani
Ph: 256-235-5877
  Birmingham
 UAB Comprehensive Cancer Center
 Clinical Trials Office - UAB Comprehensive Cancer Center
Ph: 205-934-0309
  Mobile
 Providence Cancer Center at Providence Hospital
 Thaddeus Beeker
Ph: 251-633-1890
Arizona
  Scottsdale
 Mayo Clinic Scottsdale
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
Arkansas
  Ft. Smith
 Hembree Mercy Cancer Center at St. Edward Mercy Medical Center
 John Wells, MD
Ph: 479-484-4700
California
  Berkeley
 Alta Bates Summit Comprehensive Cancer Center
 Clinical Trials Office - Alta Bates Summit Comprehensive Cancer Center
Ph: 510-204-3428
  Burlingame
 Peninsula Medical Center
 David Irwin, MD
Ph: 510-204-1591
  Castro Valley
 East Bay Radiation Oncology Center
 James Feusner, MD
Ph: 510-428-3689
 Valley Medical Oncology Consultants - Castro Valley
 James Feusner, MD
Ph: 510-428-3689
  Fairfield
 North Bay Cancer Center
 Clinical Trials Office - North Bay Cancer Center
Ph: 707-429-6976
  Fremont
 Valley Medical Oncology
 James Feusner, MD
Ph: 510-428-3689
  Fresno
 California Cancer Center - Woodward Park Office
 Dina Ibrahim
Ph: 559-451-3647
 Cancer Care Associates
 Steven Hager, DO
Ph: 559-326-1222
  Greenbrae
 Marin Cancer Institute at Marin General Hospital
 David Irwin, MD
Ph: 510-204-1591
 Sutter Health - Western Division Cancer Research Group
 David Irwin, MD
Ph: 510-204-1591
  La Jolla
 Rebecca and John Moores UCSD Cancer Center
 Clinical Trials Office - Rebecca and John Moores UCSD Cancer Center
Ph: 858-822-5354
 Email: cancercto@ucsd.edu
  Los Angeles
 USC/Norris Comprehensive Cancer Center and Hospital
 Clinical Trials Office - USC/Norris Comprehensive Cancer Center and Hospital
Ph: 323-865-0451
  Martinez
 Contra Costa Regional Medical Center
 James Feusner, MD
Ph: 510-428-3689
  Marysville
 Tibotec Therapeutics - Division of Ortho Biotech Products, LP
 Helen Chew, MD
Ph: 916-734-3771
  Modesto
 Memorial Medical Center
 Clinical Trials Office - Memorial Medical Center
Ph: 209-572-7116
  Oakland
 Alta Bates Summit Medical Center - Summit Campus
 Clinical Trials Office - Alta Bates Summit Medical Center - Summit Campus
Ph: 510-204-1414
 Bay Area Breast Surgeons, Incorporated
 James Feusner, MD
Ph: 510-428-3689
 CCOP - Bay Area Tumor Institute
 James Feusner, MD
Ph: 510-428-3689
 Highland General Hospital
 James Feusner, MD
Ph: 510-428-3689
 Larry G Strieff MD Medical Corporation
 James Feusner, MD
Ph: 510-428-3689
 Tom K Lee, Incorporated
 James Feusner, MD
Ph: 510-428-3689
  Pleasanton
 Valley Care Medical Center
 James Feusner, MD
Ph: 510-428-3689
 Valley Medical Oncology Consultants - Pleasanton
 James Feusner, MD
Ph: 510-428-3689
  Redding
 Mercy Regional Cancer Center at Mercy Medical Center
 Clinical Trials Office - Mercy Regional Cancer Center
Ph: 530-225-7471
  Sacramento
 University of California Davis Cancer Center
 Clinical Trials Office - University of California Davis Cancer Center
Ph: 916-734-3089
  San Diego
 Naval Medical Center - San Diego
 Preston Gable, MD, FACP
Ph: 619-532-7319
 Veterans Affairs Medical Center - San Diego
 Barbara Parker
Ph: 858-552-8585
  San Francisco
 California Pacific Medical Center - California Campus
 David Irwin, MD
Ph: 510-204-1591
  San Pablo
 Doctors Medical Center - San Pablo Campus
 James Feusner, MD
Ph: 510-428-3689
  Sana Rosa
 CCOP - Santa Rosa Memorial Hospital
 Ian Anderson, MD
Ph: 707-521-3830
  Truckee
 Tahoe Forest Cancer Center
 Helen Chew, MD
Ph: 916-734-3771
Colorado
  Aurora
 Aurora Presbyterian Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Boulder
 Boulder Community Hospital
 Clinical Trials Office - Boulder Community Hospital
Ph: 303-938-5253
  Colorado Springs
 Memorial Hospital Cancer Center - Colorado Springs
 Clinical Trials Office - Memorial Hospital
Ph: 719-365-2406
 Penrose Cancer Center at Penrose Hospital
 Clinical Trials Office - Penrose Cancer Center
Ph: 719-776-5275
  Denver
 CCOP - Colorado Cancer Research Program
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Porter Adventist Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 Presbyterian - St. Luke's Medical Center
 Clinical Trials Office - Presbyterian - St. Luke's Medical Center
Ph: 303-839-6000
 Rose Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Anthony Central Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
 St. Joseph Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Englewood
 Swedish Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Grand Junction
 St. Mary's Regional Cancer Center at St. Mary's Hospital and Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Greeley
 North Colorado Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Lone Tree
 Sky Ridge Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Longmont
 Hope Cancer Care Center at Longmont United Hospital
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Loveland
 McKee Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Pueblo
 St. Mary - Corwin Regional Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Thornton
 North Suburban Medical Center
 Eduardo Pajon, MD
Ph: 303-399-8020ext2261
  Wheat Ridge
 Exempla Lutheran Medical Center
 Clinical Trials Office - Exempla Lutheran Medical Center
Ph: 303-403-3605
Connecticut
  Hartford
 Helen and Harry Gray Cancer Center at Hartford Hospital
 Clinical Trials Office - Helen and Harry Gray Cancer Center
Ph: 860-545-5363
 Saint Francis/Mount Sinai Regional Cancer Center at Saint Francis Hospital and Medical Center
 Zia Rahman, MD
Ph: 860-714-4593
  Middletown
 Middlesex Hospital Cancer Center
 Susanna Hong
Ph: 860-358-2050
  Norwich
 Eastern Connecticut Hematology and Oncology Associates
 Dennis Slater, MD
Ph: 860-886-8362
Delaware
  Lewes
 Tunnell Cancer Center at Beebe Medical Center
 Clinical Trials Office - Tunnell Cancer Center
Ph: 302-645-3171
  Newark
 CCOP - Christiana Care Health Services
 Clinical Trial Office - CCOP - Christiana Care Health Services
Ph: 302-733-6227
District of Columbia
  Washington
 Sibley Memorial Hospital
 Frederick Smith, MD
Ph: 301-657-4588
 Walter Reed Army Medical Center
 Clinical Trials Office - Walter Reed Army Medical Center
Ph: 202-782-7840
Florida
  Daytona Beach
 Herbert D. Kerman Regional Oncology Center - Daytona Beach
 Ruby Anne Deveras
Ph: 386-254-4211
  Fort Lauderdale
 Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
 Clinical Trials Office - Michael and Dianne Bienes Comprehensive Cancer Center
Ph: 954-776-3239
  Hollywood
 Memorial Cancer Institute at Memorial Regional Hospital
 Clinical Trials Office - Memorial Cancer Institute
Ph: 954-985-3443
  Jacksonville
 Mayo Clinic - Jacksonville
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Jupiter
 Ella Milbank Foshay Cancer Center at Jupiter Medical Center
 Clinical Trials Office - Ella Milbank Foshay Cancer Center
Ph: 561-745-5768
  Lakeland
 Lakeland Regional Cancer Center at Lakeland Regional Medical Center
 Madhavi Venigalla, MD
Ph: 508-368-3168
  Miami Beach
 CCOP - Mount Sinai Medical Center
 Rogerio Lilenbaum, MD
Ph: 305-535-3310
  Orange Park
 Integrated Community Oncology Network - Orange Park
 Linda Struhar-Sylvester, MD, FACP
Ph: 904-272-3139
  Orlando
 Florida Hospital Cancer Institute at Florida Hospital Orlando
 Clinical Trials Office - Florida Hospital Cancer Institute
Ph: 407-303-5623
  West Palm Beach
 Palm Beach Cancer Institute - West Palm Beach
 Elisabeth McKeen, MD
Ph: 561-366-4151
Georgia
  Altanta
 Winship Cancer Institute of Emory University
 Ruth O'Regan, MD
Ph: 404-778-2208
  Columbus
 John B. Amos Cancer Center
 Clinical Trials Office - John B. Amos Cancer Center
Ph: 706-660-6404
  Gainesville
 Northeast Georgia Medical Center
 Richard LoCicero, MD
Ph: 770-297-5700
  Macon
 Medical Center of Central Georgia
 Frederick Schnell, MD, FACP
Ph: 478-743-7068
  Savannah
 Curtis and Elizabeth Anderson Cancer Institute at Memorial Health University Medical Center
 Clinical Trials Office - Curtis and Elizabeth Anderson Cancer Institute
Ph: 912-350-8568
 Nancy N. and J. C. Lewis Cancer and Research Pavilion at St. Joseph's/Candler
 Mark Taylor, MD
Ph: 912-354-6187
Idaho
  Boise
 Mountain States Tumor Institute at St. Luke's Regional Medical Center
 Theodore Walters, MD
Ph: 208-381-2711
Illinois
  Alton
 Saint Anthony's Hospital at Saint Anthony's Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Chicago
 Creticos Cancer Center at Advocate Illinois Masonic Medical Center
 Clinical Trials Office - Creticos Cancer Center at Advocate Illinois Masonic Medical Center
Ph: 773-296-5360
 Hematology and Oncology Associates
 Clinical Trails Office - Hematology and Oncology Associates
Ph: 312-695-1301
 University of Chicago Cancer Research Center
 Clinical Trials Office - University of Chicago Cancer Research Center
Ph: 773-834-7424
 University of Illinois Cancer Center
 Clinical Trial Office - University of Illinois Cancer Center
Ph: 312-355-3046
  Decatur
 Decatur Memorial Hospital Cancer Care Institute
 Clinical Trials Office - Decatur Memorial Hospital Cancer Care Institute
Ph: 217-876-6601
  Elk Grove Village
 Alexian Brothers Radiation Oncology
 Bruce Bank, MD
Ph: 847-437-3312
  Harvey
 Ingalls Cancer Care Center at Ingalls Memorial Hospital
 Clinical Trials Office - Ingalls Cancer Care Center at Ingalls Memorial Hospital
Ph: 708-915-6747
  Joliet
 Joliet Oncology-Hematology Associates, Limited - West
 Kendrith Rowland, MD
Ph: 217-383-3019
 Midwest Center for Hematology/Oncology
 William Gradishar, MD
Ph: 312-695-4125
  Kankakee
 Provena St. Mary's Regional Cancer Center - Kankakee
 Riaz Elahi, MD
Ph: 708-873-4500
  Maywood
 Cardinal Bernardin Cancer Center at Loyola University Medical Center
 Clinical Trials Office - Cardinal Bernardin Cancer Center
Ph: 708-226-4357
  Moline
 Trinity Cancer Center at Trinity Medical Center - 7th Street Campus
 Costas Constantinou, MD
Ph: 563-359-9876
  Mt. Vernon
 Good Samaritan Regional Health Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Oak Lawn
 Advocate Christ Medical Center
 Thomas M. Hoeltgen, MD
Ph: 708-424-9710
  Olympia Fields
 Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields
 Clinical Trials Office - Saint James Hospital and Health Centers Comprehensive Cancer Institute - Olympia Fields
Ph: 708-679-2217
  Park Ridge
 Advocate Lutheran General Cancer Care Center
 Clinical Trials Office - Advocate Lutheran General Cancer Care Center
Ph: 847-384-3621
  Rockford
 Center for Cancer Care at OSF Saint Anthony Medical Center
 Clinical Trials Office - Center for Cancer Care at OSF Saint Anthony Medical Center
Ph: 815-227-2633
 Swedish-American Regional Cancer Center
 Clinical Trials Office - Swedish-American Regional Cancer Center
Ph: 815-489-4413
  Springfield
 Regional Cancer Center at Memorial Medical Center
 Clinical Trials Office - Regional Cancer Center at Memorial Medical Center
Ph: 217-788-4233
Indiana
  Beech Grove
 St. Francis Hospital and Health Centers - Beech Grove Campus
 Howard Gross, MD
Ph: 937-832-1093
  Elkhart
 Elkhart General Hospital
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  Fort Wayne
 Fort Wayne Medical Oncology and Hematology
 Sreenivasa Nattam, MD
Ph: 260-484-8830
  Indianapolis
 Community Regional Cancer Care at Community Hospital East
 Radhika Walling
Ph: 317-355-5347
 Community Regional Cancer Care at Community Hospital North
 Radhika Walling
Ph: 317-621-4300
  Kokomo
 Howard Community Hospital
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  La Porte
 Center for Cancer Therapy at LaPorte Hospital and Health Services
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  Richmond
 Reid Hospital & Health Care Services
 Howard Gross, MD
Ph: 937-832-1093
  South Bend
 CCOP - Northern Indiana CR Consortium
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
 Memorial Hospital of South Bend
 Clinical Trials Office - Memorial Hospital of South Bend
Ph: 800-284-7370
 Saint Joseph Regional Medical Center
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
 South Bend Clinic
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
Iowa
  Ames
 McFarland Clinic, PC
 Clinical Trials Office - McFarland Clinic, PC
Ph: 515-239-2621
  Bettendorf
 Hematology Oncology Associates of the Quad Cities
 Shobha Chitneni, MD, MBBS
Ph: 563-355-7733
  Cedar Rapids
 Cedar Rapids Oncology Associates
 Clinical Trials Office - Cedar Rapids Oncology Associates
Ph: 319-363-2690
 Iowa Blood and Cancer Care
 David Zenk, MD
Ph: 319-369-7091
 Mercy Regional Cancer Center at Mercy Medical Center
 David Zenk, MD
Ph: 319-369-7091
 St. Luke's Hospital
 David Zenk, MD
Ph: 319-369-7091
  Council Bluffs
 Heartland Oncology and Hematology
 John Okerbloom, MD
Ph: 712-322-4136
  Davenport
 Genesis Regional Cancer Center at Genesis Medical Center
 George Kovach, MD
Ph: 563-421-1960
  Des Moines
 CCOP - Iowa Oncology Research Association
 Robert Behrens
Ph: 515-244-7586
888-244-6061
 John Stoddard Cancer Center at Iowa Lutheran Hospital
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Lutheran Hospital
Ph: 515-241-8704
 John Stoddard Cancer Center at Iowa Methodist Medical Center
 Clinical Trials Office - John Stoddard Cancer Center at Iowa Methodist Medical Center
Ph: 515-241-6727
 Medical Oncology and Hematology Associates at John Stoddard Cancer Center
 Robert Behrens
Ph: 515-282-2921
 Medical Oncology and Hematology Associates at Mercy Cancer Center
 Robert Behrens
Ph: 515-643-8740
 Mercy Cancer Center at Mercy Medical Center - Des Moines
 Robert Behrens
Ph: 515-643-8206
888-221-4849
  Iowa City
 Holden Comprehensive Cancer Center at University of Iowa
 Cancer Information Service
Ph: 800-237-1225
Kansas
  Chanute
 Cancer Center of Kansas, PA - Chanute
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Dodge City
 Cancer Center of Kansas, PA - Dodge City
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  El Dorado
 Cancer Center of Kansas, PA - El Dorado
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Independence
 Cancer Center of Kansas-Independence
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Kingman
 Cancer Center of Kansas, PA - Kingman
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Lawrence
 Lawrence Memorial Hospital
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Liberal
 Southwest Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Newton
 Cancer Center of Kansas, PA - Newton
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Overland Park
 Menorah Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Parsons
 Cancer Center of Kansas, PA - Parsons
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Pratt
 Cancer Center of Kansas, PA - Pratt
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Salina
 Cancer Center of Kansas, PA - Salina
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Shawnee Mission
 Shawnee Mission Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Topeka
 Cotton-O'Neil Cancer Center
 Clinical Trials Office - Cotton-O'Neil Cancer Center
Ph: 785-270-4963
 St. Francis Comprehensive Cancer Center
 Michael Hurwitz, MD
Ph: 785-295-7800
  Wellington
 Cancer Center of Kansas, PA - Wellington
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Wichita
 Associates in Womens Health, PA - North Review
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Cancer Center of Kansas, PA - Medical Arts Tower
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 CCOP - Wichita
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
 Via Christi Cancer Center at Via Christi Regional Medical Center
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
  Winfield
 Cancer Center of Kansas, PA - Winfield
 Shaker Dakhil, MD, FACP
Ph: 316-262-4467
Kentucky
  Ashland
 Cancer Resource Center at King's Daughters Medical Center
 Clinical Trial Office - Cancer Resource Center at Kings Daughter's Medical Center
Ph: 606-327-6499
  Madisonville
 Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
 Clinical Trials Office - Merle M. Mahr Cancer Center at Regional Medical Center of Hopkins County
Ph: 800-733-2312
Louisiana
  Baton Rouge
 Mary Bird Perkins Cancer Center - Baton Rouge
 Robert Veith
Ph: 225-767-0847
 Ochsner Health Center - Bluebonnet
 Jyotsna Fuloria
Ph: 225-761-5200
 Pennington Cancer Center at Baton Rouge General
 Clinical Trials Office - Pennington Cancer Center at Baton Rouge General
Ph: 225-381-6451
  Houma
 Terrebonne General Medical Center
 Jyotsna Fuloria
Ph: 985-850-6300
  New Orleans
 CCOP - Ochsner
 Jyotsna Fuloria
Ph: 504-842-3910
 MBCCOP - LSU Health Sciences Center
 Robert Veith
Ph: 504-568-5151
 Medical Center of Louisiana - New Orleans
 Robert Veith
Ph: 504-903-2311
 Ochsner Cancer Institute at Ochsner Clinic Foundation
 Jyotsna Fuloria
Ph: 504-842-4360
888-624-7637
Maine
  Bangor
 CancerCare of Maine at Eastern Maine Medical Center
 Clinical Trials Office - CancerCare of Maine
Ph: 207-973-4274
  Scarborough
 Maine Center for Cancer Medicine and Blood Disorders - Scarborough
 Tracey Weisberg, MD
Ph: 207-885-7634
  Waterville
 MaineGeneral Medical Center - Waterville
 Clinical Trials Office - MaineGeneral Medical Center - Waterville
Ph: 207-872-1792
Maryland
  Baltimore
 Alvin and Lois Lapidus Cancer Institute at Sinai Hospital
 Cristina Truica, MD
Ph: 410-601-4710
 Greenebaum Cancer Center at University of Maryland Medical Center
 Clinical Trials Office - Greenebaum Cancer Center at University of Maryladn Medical Center
Ph: 800-888-8823
 Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
 Clinical Trials Office - Sidney Kimmel Comprehensive Cancer Center at John Hopkins
Ph: 410-955-8804
 Email: jhcccro@jhmi.edu
  Elkton MD
 Union Hospital Cancer Program at Union Hospital
 Stephen Grubbs, MD
Ph: 302-366-1200
  Frederick
 Frederick Memorial Hospital Regional Cancer Therapy Center
 Brian O'Connor, MD
Ph: 301-662-8477
  Salisbury
 Peninsula Regional Medical Center
 Clinical Trials Office - Peninsula Regional Medical Center
Ph: 410-543-7000
Massachusetts
  Attleboro
 Sturdy Memorial Hospital
 Michael Vasconcelles, MD
Ph: 617-632-5301
  Boston
 Dana-Farber/Brigham and Women's Cancer Center
 Clinical Trials Office
Ph: 617-724-5200
 Dana-Farber/Harvard Cancer Center at Dana Farber Cancer Institute
 Lawrence Shulman, MD
Ph: 617-632-2277
 Massachusetts General Hospital
 Clinical Trials Office - Massachusetts General Hospital
Ph: 877-726-5130
  Burlington
 Lahey Clinic Medical Center - Burlington
 Clinical Trials Office - Lahey Clinic Medical Center - Burlington
Ph: 781-744-8027
  Fall River
 Hudner Oncology Center at Saint Anne's Hospital - Fall River
 Clinical Trials Office - Hudner Oncology Center at Saint Anne's Hospital - Fall River
Ph: 508-674-5600 ext. 2019
  Gloucester
 Addison Gilbert Hospital
 Angus McIntyre, MD
Ph: 978-927-6850
  Hyannis
 Cape Cod Hospital
 David Lovett, MD
Ph: 508-862-7575
  Lowell
 Lowell General Hospital
 Lawrence Shulman, MD
Ph: 617-632-2277
  Norwood
 Caritas Norwood Hospital
 Karen Scanlan
Ph: 781-769-2950
  Peabody
 NSMC Cancer Center - Peabody
 Joel Schwartz, MD
Ph: 978-977-3434
  Pittsfield
 Berkshire Hematology Oncology, PC
 Harvey Zimbler, MD
Ph: 413-496-8205
  South Weymouth
 South Shore Hospital
 Lawrence Shulman, MD
Ph: 617-632-2277
  Westfield
 Noble Hospital
 Philip Glynn
Ph: 413-568-2811
  Worcester
 UMASS Memorial Cancer Center - University Campus
 Kathryn Edmiston, MD
Ph: 508-334-5141
Michigan
  Adrian
 Hickman Cancer Center at Bixby Medical Center
 Clinical Trials Office - Hickman Cancer Center at Bixby Medical Center
Ph: 517-265-0116
  Ann Arbor
 CCOP - Michigan Cancer Research Consortium
 Philip Stella, MD
Ph: 734-712-1000
 Saint Joseph Mercy Cancer Center
 Philip Stella, MD
Ph: 734-712-1000
 University of Michigan Comprehensive Cancer Center
 Clinical Trials Office - University of Michigan Comprehensive Cancer Center
Ph: 800-865-1125
  Battle Creek
 Battle Creek Health System Cancer Care Center
 Martin Bury
Ph: 616-966-8000
  Big Rapids
 Mecosta County Medical Center
 Martin Bury
Ph: 231-796-8691
  Dearborn
 Oakwood Cancer Center at Oakwood Hospital and Medical Center
 Clinical Trials Office - Oakwood Cancer Center at Oakwood Hospital and Medical Center
Ph: 313-593-8090
  Flint
 Genesys Hurley Cancer Institute
 Clinical Trials Office - Genesys Hurley Cancer Institute
Ph: 810-762-8057
 Hurley Medical Center
 Clinical Trials Office - Hurley Medical Center
Ph: 810-762-8057
  Grand Rapids
 Butterworth Hospital at Spectrum Health
 Martin Bury
Ph: 616-391-2799
 CCOP - Grand Rapids
 Martin Bury
Ph: 616-391-1230
 Lacks Cancer Center at Saint Mary's Health Care
 Martin Bury
Ph: 616-752-5222
  Grosse Pointe Woods
 Van Elslander Cancer Center at St. John Hospital and Medical Center
 Clincial Trials Office - Van Elslander Cancer Center at St. John Hospital and Medical Center
Ph: 313-343-3166
  Jackson
 Foote Memorial Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Kalamazoo
 Borgess Medical Center
 Raymond Lord, MD
Ph: 269-373-7458
 Bronson Methodist Hospital
 Raymond Lord, MD
Ph: 269-373-7458
 West Michigan Cancer Center
 Clinical Trials Office - West Michigan Cancer Center
Ph: 269-373-7458
  Lambertville
 Haematology-Oncology Associates of Ohio and Michigan, PC
 Paul Schaefer, MD
Ph: 419-479-5605
  Lansing
 Sparrow Regional Cancer Center
 Clinical Trials Office - Sparrow Regional Cancer Center
Ph: 517-364-2890
  Livonia
 St. Mary Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Monroe
 Community Cancer Center of Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
 Mercy Memorial Hospital - Monroe
 Paul Schaefer, MD
Ph: 419-479-5605
  Petoskey
 Northern Michigan Hospital
 Lisa Galloway
Ph: 231-487-4000
800-248-6777
  Pontiac
 St. Joseph Mercy Oakland
 Philip Stella, MD
Ph: 734-712-1000
  Port Huron
 Mercy Regional Cancer Center at Mercy Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Royal Oak
 William Beaumont Hospital - Royal Oak Campus
 Clinical Trials Office - William Beaumont Hospital - Royal Oak Campus
Ph: 248-551-7695
  Saginaw
 Seton Cancer Institute at Saint Mary's - Saginaw
 Clinical Trials Office - Seton Cancer Institute - Saginaw
Ph: 989-776-8411
  Saint Joseph
 Oncology Care Associates, PLLC
 Eric Lester, MD
Ph: 269-985-0029
  Southfield
 Providence Cancer Institute at Providence Hospital - Southfield Campus
 Judie Goodman, DO
Ph: 248-552-6000
  St. Joseph
 Lakeland Regional Cancer Care Center - St. Joseph
 Rafat Ansari, MD, FACP
Ph: 574-234-5123
  Traverse City
 Munson Medical Center
 Martin Bury
Ph: 231-935-6202
  Warren
 St. John Macomb Hospital
 Philip Stella, MD
Ph: 734-712-1000
  Wyoming
 Metro Health Hospital
 Martin Bury
Ph: 616-252-7200
Minnesota
  Bemidji
 MeritCare Bemidji
 Preston Steen, MD
Ph: 701-234-2397
  Burnsville
 Fairview Ridges Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Coon Rapids
 Mercy and Unity Cancer Center at Mercy Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Duluth
 CCOP - Duluth
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 Duluth Clinic Cancer Center - Duluth
 Clinical Trials Office - Duluth Clinic Cancer Center - Duluth
Ph: 218-786-3308
 Miller - Dwan Medical Center
 Daniel Nikcevich, MD, PhD
Ph: 218-786-3625
 St. Luke's Hospital Cancer Care Center
 Tanya Repka, MD, FACP
Ph: 218-726-3081
  Edina
 Fairview Southdale Hospital
 Clinical Trials Office - Fairview Southdale Hospital
Ph: 612-625-3650
  Fergus Falls
 Donald Jurgens
Ph: 320-229-4907
  Fridley
 Mercy and Unity Cancer Center at Unity Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Hutchinson
 Hutchinson Area Health Care
 Daniel Anderson
Ph: 320-234-5000
800-454-3903
  Mankato
 Immanuel St. Joseph's
 Glenn Harman, MD
Ph: 815-777-1536
  Maplewood
 HealthEast Cancer Care at St. John's Hospital
 Daniel Anderson
Ph: 651-232-7970
 Minnesota Oncology Hematology, PA - Maplewood
 Patrick Flynn, MD
Ph: 612-863-8585
  Minneapolis
 Hennepin County Medical Center - Minneapolis
 Clinical Trials Office - Hennepin County Medical Center - Minneapolis
Ph: 612-873-5911
 Masonic Cancer Center at University of Minnesota
 Clinical Trials Office - Masonic Cancer Center at University of Minnesota
Ph: 612-624-2620
 Virginia Piper Cancer Institute at Abbott - Northwestern Hospital
 Clinical Trials Office - Virginia Piper Cancer Institute
Ph: 612-863-5654
  Robbinsdale
 Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
 Clinical Trials Office - Hubert H. Humphrey Cancer Center at North Memorial Outpatient Center
Ph: 763-520-1893
  Rochester
 Mayo Clinic Cancer Center
 Clinical Trials Office - All Mayo Clinic Locations
Ph: 507-538-7623
  Saint Cloud
 CentraCare Clinic - River Campus
 Donald Jurgens
Ph: 320-229-4907
  Saint Louis Park
 CCOP - Metro-Minnesota
 Patrick Flynn, MD
Ph: 612-863-8585
 Park Nicollet Cancer Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Saint Paul
 United Hospital
 Patrick Flynn, MD
Ph: 612-863-8585
  Shakopee
 St. Francis Cancer Center at St. Francis Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  St. Paul
 Regions Hospital Cancer Care Center
 Clinical Trials Office - Regions Hospital Cancer Care Center
Ph: 651-254-1517
  Waconia
 Ridgeview Medical Center
 Patrick Flynn, MD
Ph: 612-863-8585
  Woodbury
 Minnesota Oncology Hematology, PA - Woodbury
 Patrick Flynn, MD
Ph: 612-863-8585
Mississippi
  Hattiesburg
 Hattiesburg Clinic, PA at Forrest General
 Jyotsna Fuloria
Ph: 601-288-8282
 Hematology & Oncology Clinic
 Jyotsna Fuloria
Ph: 601-268-5150
  Jackson
 University of Mississippi Cancer Clinic
 Barbara Craft
Ph: 601-984-5590
  Pascagoula
 Regional Cancer Center at Singing River Hospital
 James Clarkson, MD
Ph: 228-374-6296
Missouri
  Cape Girardeau
 Saint Francis Medical Center
 Bethany Sleckman, MD
Ph: 314-251-7057
  Chesterfield
 Saint Luke's Hospital
 Donald Busiek, MD
Ph: 314-205-6737
  Independence
 Independence Regional Health Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Joplin
 St. John's Regional Medical Center
 Clinical Trials Office - St. John's Regional Medical Center
Ph: 417-625-2488 ext. 2949
  Kansas City
 CCOP - Kansas City
 Rakesh Gaur, MD
Ph: 816-823-0555
 North Kansas City Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
 Parvin Radiation Oncology
 Rakesh Gaur, MD
Ph: 816-823-0555
 Research Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Saint Luke's Cancer Institute at Saint Luke's Hospital
 Rakesh Gaur, MD
Ph: 816-823-0555
 St. Joseph Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
 Truman Medical Center - Hospital Hill
 Rakesh Gaur, MD
Ph: 816-823-0555
  Saint Joseph
 Heartland Regional Medical Center
 Rakesh Gaur, MD
Ph: 816-823-0555
  Saint Louis
 Arch Medical Services, Incorporated at Center for Cancer Care and Research
 Alan Lyss, MD
Ph: 314-996-5514
 CCOP - St. Louis-Cape Girardeau
 Bethany Sleckman, MD
Ph: 314-251-7057
 David C. Pratt Cancer Center at St. John's Mercy
 Clinical Trials Office - David C. Pratt Cancer Center at St. John's Mercy
Ph: 314-251-6770
 Midwest Hematology Oncology Group, Incorporated
 Bethany Sleckman, MD
Ph: 314-251-7057
 Missouri Baptist Cancer Center
 Alan Lyss, MD
Ph: 314-996-5514
 Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
 Michael Naughton, MD
Ph: 314-996-8872
  Springfield
 CCOP - Cancer Research for the Ozarks
 Robert Carolla
Ph: 417-269-4520
 Hulston Cancer Center at Cox Medical Center South
 Robert Carolla
Ph: 417-269-5257
 St. John's Regional Health Center
 Robert Carolla
Ph: 417-820-2000
Montana
  Billings
 Billings Clinic - Downtown
 Clinical Trials Office - Billings Clinic - Downtown
Ph: 800-996-2663
 Email: research@billingsclinic.org
 CCOP - Montana Cancer Consortium
 Benjamin Marchello, MD
Ph: 406-238-6290
 Hematology-Oncology Centers of the Northern Rockies - Billings
 Benjamin Marchello, MD
Ph: 406-238-6290
 Northern Rockies Radiation Oncology Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 St. Vincent Healthcare Cancer Care Services
 Benjamin Marchello, MD
Ph: 406-238-6290
  Bozeman
 Bozeman Deaconess Cancer Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Butte
 St. James Healthcare Cancer Care
 Benjamin Marchello, MD
Ph: 406-238-6290
  Great Falls
 Benjamin Marchello, MD
Ph: 406-238-6290
 Great Falls Clinic - Main Facility
 Benjamin Marchello, MD
Ph: 406-238-6290
 Sletten Cancer Institute at Benefis Healthcare
 Grant Harrer, MD, FACP, CCTI
Ph: 406-731-8100
  Helena
 St. Peter's Hospital
 Benjamin Marchello, MD
Ph: 406-238-6290
  Kalispell
 Glacier Oncology, PLLC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Medical Oncology at KRMC
 Benjamin Marchello, MD
Ph: 406-238-6290
 Kalispell Regional Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
  Missoula
 Community Medical Center
 Benjamin Marchello, MD
Ph: 406-238-6290
 Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
 Clinical Trials Office - Montana Cancer Center at St. Patrick Hospital and Health Sciences Center
Ph: 406-329-7029
 Montana Cancer Specialists at Montana Cancer Center
 Clinical Trials Office - Montana Cancer Specialists at Montana Cancer Center
Ph: 406-238-6962
Nebraska
  Grand Island
 Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center
 Elizabeth Reed, MD
Ph: 402-559-5388
  Kearney
 Good Samaritan Cancer Center at Good Samaritan Hospital
 Clinical Trials Office - Good Samaritan Cancer Center at Good Samaritan Hospital
Ph: 308-865-7963
  Lincoln
 Cancer Resource Center - Lincoln
 Alan Berg, MD
Ph: 402-420-7000
  North Platte
 Callahan Cancer Center at Great Plains Regional Medical Center
 Clinical Trials Office - Callahan Cancer Center at Great Plains Regional Medical Center
Ph: 308-696-7864
  Omaha
 Alegant Health Cancer Center at Bergan Mercy Medical Center
 Clinical Trials Office - Alegant Health Cancer Center at Bergen Mercy Medical Center
Ph: 402-398-6060
 CCOP - Missouri Valley Cancer Consortium
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Creighton University Medical Center
 Clinical Trials Office - Creighton University Medical Center
Ph: 402-280-4100
 Immanuel Medical Center
 Gamini Soori, MD, FACP, FRCP, MBA
Ph: 402-393-3110
 Methodist Estabrook Cancer Center
 Robert Langdon, MD
Ph: 402-399-8762
 UNMC Eppley Cancer Center at the University of Nebraska Medical Center
 Clinical Trials Office - UNMC Eppley Cancer Center at the University of Nebraska Medical Center
Ph: 800-999-5465
Nevada
  Las Vegas
 CCOP - Nevada Cancer Research Foundation
 John Ellerton, MD, CM
Ph: 702-384-0013
 University Medical Center of Southern Nevada
 John Ellerton, MD, CM
Ph: 702-384-0013
New Hampshire
  Concord
 New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
 Charles Catcher, MD
Ph: 603-224-2556
  Hooksett
 New Hampshire Oncology - Hematology, PA - Hooksett
 Charles Catcher, MD
Ph: 603-224-2556
  Laconia
 Lakes Region General Hospital
 Charles Catcher, MD
Ph: 603-224-2556
  Lebanon
 Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
 Clinical Trials Office - Norris Cotton Cancer Center
Ph: 603-650-7609
 Email: cancerhelp@dartmouth.edu
  Manchester
 Elliot Regional Cancer Center at Elliot Hospital
 Douglas Weckstein, MD
Ph: 603-622-6484
  Portsmouth
 Portsmouth Regional Hospital
 Paul Poulin
Ph: 603-436-5110
800-685-8282
New Jersey
  Morristown
 Carol G. Simon Cancer Center at Morristown Memorial Hospital
 Steven Papish, MD
Ph: 973-538-5210
  New Brunswick
 Cancer Institute of New Jersey at UMDNJ - Robert Wood Johnson Medical School
 Clinical Trials Office - Cancer Institute of New Jersey
Ph: 732-235-8675
  Somerville
 Somerset Medical Center
 Clinical Trials Office - Somerset Medical Center
Ph: 908-685-2481
  Summit
 Overlook Hospital
 Steven Papish, MD
Ph: 973-538-5210
  Vineland
 Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare
 Clinical Trials Office - Franklin & Edith Scarpa Regional Cancer Center at South Jersey Healthcare
Ph: 856-641-7933
  Voorhees
 Cancer Institute of New Jersey at Cooper - Voorhees
 Clinical Trials Office - Cancer Institute of New Jersey at Cooper University Hospital - Voorhees
Ph: 856-325-6757
New York
  Bronx
 Albert Einstein Cancer Center at Albert Einstein College of Medicine
 Clinical Trials Office - Albert Einstein Cancer Center at Albert Einstein College of Medicine
Ph: 718-904-2730
 Email: aecc@aecom.yu.edu
 Our Lady of Mercy Medical Center Comprehensive Cancer Center
 Peter Wiernik, MD
Ph: 718-304-7200
  Buffalo
 Roswell Park Cancer Institute
 Clinical Trials Office - Roswell Park Cancer Institute
Ph: 877-275-7724
  East Syracuse
 CCOP - Hematology-Oncology Associates of Central New York
 Jeffrey Kirshner, MD
Ph: 315-472-7504
  Elmhurst
 Elmhurst Hospital Center
 Clinical Trials Office - Elmhurst Hospital Center
Ph: 718-883-3177
  Jamaica
 Queens Cancer Center of Queens Hospital
 Lewis Silverman, MD
Ph: 212-241-5520
  New York
 Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
 Clinical Trials Office - Herbert Irving Comprehensive Cancer Center at Columbia University Medical Center
Ph: 212-305-8615
 Memorial Sloan-Kettering Cancer Center
 Diana Lake, MD
Ph: 212-639-8953
 Mount Sinai Medical Center
 Lewis Silverman, MD
Ph: 212-241-5520
  Plattsburgh
 Fitzpatrick Cancer Center at Champlain Valley Physicians Hospital Medical Center
 Jan Duus, MD
Ph: 518-562-7110
  Rochester
 Highland Hospital of Rochester
 Richard Fisher, MD
Ph: 585-275-0842
 James P. Wilmot Cancer Center at University of Rochester Medical Center
 Richard Fisher, MD
Ph: 585-275-0842
 Lipson Cancer and Blood Center at Rochester General Hospital
 Peter Bushunow, MD
Ph: 585-922-4020
  Stony Brook
 Stony Brook University Cancer Center
 Clinical Trials Office - Stony Brook University Cancer Center
Ph: 800-862-2215
  Syracuse
 SUNY Upstate Medical University Hospital
 Clinical Trials Office - SUNY Upstate Medical University Hospital
Ph: 315-464-5476
  Utica
 Faxton Regional Cancer Center
 Atul Butala, MD, FACP
Ph: 315-798-9300
North Carolina
  Asheboro
 Randolph Hospital
 Clinical Trails Office - Randolph Hospital
Ph: 336-832-0821
  Chapel Hill
 Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
 Clinical Trials Office - Lineberger Comprehensive Cancer Center
Ph: 877-668-0683; 919-966-4432
  Concord
 Batte Cancer Center at Northeast Medical Center
 James Wall, MD
Ph: 704-783-1370
  Durham
 Duke Comprehensive Cancer Center
 Clinical Trials Office - Duke Comprehensive Cancer Center
Ph: 888-275-3853
  Fayetteville
 Cape Fear Valley Medical Center Cancer Center
 Clinical Trial Office - Cape Fear Valley Medical Center Cancer Center
Ph: 910-609-4561
  Goldsboro
 Wayne Memorial Hospital, Incorporated
 James Atkins, MD
Ph: 919-580-0000
  Greensboro
 Moses Cone Regional Cancer Center at Wesley Long Community Hospital
 Clinical Trials Office - Moses Cone Regional Cancer Center at Wesley Long Community Hospital
Ph: 336-621-8374
  Greenville
 Leo W. Jenkins Cancer Center at ECU Medical School
 Clinical Trials Office - Leo W. Jenkins Cancer Center at ECU Medical School
Ph: 252-744-2391
  Henderson
 Maria Parham Medical Center
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Hendersonville
 Pardee Memorial Hospital
 James Radford, MD
Ph: 828-692-8045
  Kinston
 Kinston Medical Specialists
 Peter Watson, MD
Ph: 252-559-2200ext.201
  Lumberton
 Southeastern Regional Medical Center
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Oxford
 Granville Medical Center
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Raleigh
 Duke Health Raleigh Hospital
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Reidsville
 Annie Penn Cancer Center
 Clinical Trials Office - Annie Penn Cancer Center
Ph: 336-621-8374
  Roxboro
 Person Memorial Hospital
 Jeffrey Crawford, MD
Ph: 919-681-9509
  Statesville
 Iredell Memorial Hospital
 Ruby Grimm, MD
Ph: 704-873-2219
  Washington
 Marion L. Shepard Cancer Center at Beaufort County Hospital
 Jennie Crews
Ph: 252-975-4308
  Wilmington
 Zimmer Cancer Center at New Hanover Regional Medical Center
 Cyrus Kotwall, MD
Ph: 910-763-4630
  Winston-Salem
 Wake Forest University Comprehensive Cancer Center
 Clinical Trials Office - Wake Forest University Comprehensive Cancer Center
Ph: 336-713-6771
North Dakota
  Bismarck
 Bismarck Cancer Center
 Edward Wos, DO
Ph: 701-323-5741
 Medcenter One Hospital Cancer Care Center
 Edward Wos, DO
Ph: 701-323-5741
 Mid Dakota Clinic, PC
 Clinical Trials Office - Mid Dakota Clinic, PC
Ph: 701-530-6950
 St. Alexius Medical Center Cancer Center
 Clinical Trials Office - St. Alexius Medical Center Cancer Center
Ph: 701-530-6950
  Fargo
 CCOP - MeritCare Hospital
 Preston Steen, MD
Ph: 701-234-2397
 MeritCare Broadway
 Preston Steen, MD
Ph: 701-234-2397
  Grand Forks
 Altru Cancer Center at Altru Hospital
 Clinical Trails Office - Altru Cancer Center at Altru Hospital
Ph: 701-780-6520
  Minot
 Trinity CancerCare Center
 Contact Person
Ph: 701-857-3535
800-862-0005
Ohio
  Akron
 Summa Center for Cancer Care at Akron City Hospital
 Clinical Trials Office - Akron City Hospital
Ph: 330-375-6101
  Barberton
 Barberton Citizens Hospital
 Jennifer Payne
Ph: 330-745-1611
  Bowling Green
 Wood County Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
  Canton
 Aultman Cancer Center at Aultman Hospital
 Clinical Trials Office - Aultman Cancer Center at Aultman Hospital
Ph: 330-363-6891
 Mercy Cancer Center at Mercy Medical Center
 Mitchell Haut, MD
Ph: 330-453-9993
  Chillicothe
 Adena Regional Medical Center
 Clinical Trials Office - Adena Regional Medical Center
Ph: 877-779-7585
  Cleveland
 Case Comprehensive Cancer Center
 Clinical Trials Office - Case Comprehensive Cancer Center
Ph: 800-641-2422
 Cleveland Clinic Taussig Cancer Center
 Clinical Trials Office - Cleveland Clinic Taussig Cancer Center
Ph: 866-223-8100
 MetroHealth Cancer Care Center at MetroHealth Medical Center
 Bruce Averbook, MD, FACS
Ph: 216-778-4795
  Columbus
 Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center
 Ohio State University Cancer Clinical Trial Matching Service
Ph: 866-627-7616
 Email: osu@emergingmed.com
 CCOP - Columbus
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Doctors Hospital at Ohio Health
 Clinical Trials Office - Doctors Hospital at Ohio Health
Ph: 614-566-3275
 Grant Medical Center Cancer Care
 Clinical Trials Office - Grant Medical Center Cancer Care
Ph: 614-566-4475
 Mount Carmel Health - West Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Riverside Methodist Hospital Cancer Care
 Clinical Trials Office - Riverside Methodist Hospital Cancer Care
Ph: 614-566-4475
  Dayton
 CCOP - Dayton
 Howard Gross, MD
Ph: 937-832-1093
 David L. Rike Cancer Center at Miami Valley Hospital
 Clinical Trials Office - David L. Rike Cancer Center at Miami Valley Hospital
Ph: 937-208-2079
 Good Samaritan Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Grandview Hospital
 Howard Gross, MD
Ph: 937-832-1093
 Samaritan North Cancer Care Center
 Howard Gross, MD
Ph: 937-832-1093
  Delaware
 Grady Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Findlay
 Blanchard Valley Medical Associates
 Howard Gross, MD
Ph: 937-832-1093
  Franklin
 Middletown Regional Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Greenville
 Wayne Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Kettering
 Charles F. Kettering Memorial Hospital
 Clinical Trials Office - Charles F. Kettering Memorial Hospital
Ph: 937-298-3399 ext. 57556
  Lancaster
 Fairfield Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Lima
 Lima Memorial Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Rita's Medical Center
 Clinical Trials Office - St. Rita's Medical Center
Ph: 419-226-9617
  Marietta
 Strecker Cancer Center at Marietta Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Maumee
 Northwest Ohio Oncology Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Luke's Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
  Newark
 Licking Memorial Cancer Care Program at Licking Memorial Hospital
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Oregon
 St. Charles Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic - Oregon
 Paul Schaefer, MD
Ph: 419-479-5605
  Sandusky
 North Coast Cancer Care, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Springfield
 Community Hospital of Springfield and Clark County
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
 Mercy Medical Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Sylvania
 Flower Hospital Cancer Center
 Clinical Trials Office - Flower Hospital Cancer Center
Ph: 419-824-1842
  Tiffin
 Mercy Hospital of Tiffin
 Paul Schaefer, MD
Ph: 419-479-5605
  Toledo
 CCOP - Toledo Community Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 Medical University of Ohio Cancer Center
 Clinical Trials Office - Medical University of Ohio Cancer Center
Ph: 419-383-6583
 St. Anne Mercy Hospital
 Paul Schaefer, MD
Ph: 419-479-5605
 St. Vincent Mercy Medical Center
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Clinic, Incorporated - Main Clinic
 Paul Schaefer, MD
Ph: 419-479-5605
 Toledo Hospital
 Clinical Trials Office - Toledo Hospital
Ph: 419-824-1842
  Troy
 UVMC Cancer Care Center at Upper Valley Medical Center
 Clinical Trials Office - UVMC Cancer Care Center at Upper Valley Medical Center
Ph: 937-440-4842
  Wauseon
 Fulton County Health Center
 Clinical Trials Office - Fulton County Health Center
Ph: 419-330-2708
  Westerville
 Mount Carmel St. Ann's Cancer Center
 J. Philip Kuebler, MD, PhD
Ph: 614-442-3130
  Wilmington
 Clinton Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
  Wooster
 Cleveland Clinic - Wooster
 Clinical Trials Office - Cleveland Clinic - Wooster
Ph: 800-862-7798
  Wright-Patterson Afb
 United States Air Force Medical Center - Wright-Patterson
 Roger Wood
Ph: 937-257-9133
  Xenia
 Ruth G. McMillan Cancer Center at Greene Memorial Hospital
 Howard Gross, MD
Ph: 937-832-1093
Oklahoma
  Lawton
 Cleo Craig Cancer Research Clinic
 Nadim Nimeh, MD
Ph: 580-536-2121ext.113
  Oklahoma City
 Cancer Care Associates - Mercy Campus
 Howard Ozer, MD, PhD
Ph: 405-271-4022
 Oklahoma University Cancer Institute
 Howard Ozer, MD, PhD
Ph: 405-271-4022
  Tulsa
 Natalie Warren Bryant Cancer Center at St. Francis Hospital
 David Barnes, MD, FACS
Ph: 423-778-8582
Oregon
  Grants Pass
 Three Rivers Community Hospital
 Charles Dibb, MD
Ph: 541-774-5853
  Gresham
 Legacy Mount Hood Medical Center
 Clinical Trials Office - Legacy Mount Hood Medical Center
Ph: 503-413-2150
  Medford
 Dubs Cancer Center at Rogue Valley Medical Center
 Charles Dibb, MD
Ph: 541-774-5853
 Providence Cancer Center at PMCC
 Charles Dibb, MD
Ph: 541-774-5853
  Milwaukie
 Providence Milwaukie Hospital
 Janet Ruzich
Ph: 503-513-8300
  Portland
 Adventist Medical Center
 Janet Ruzich
Ph: 503-257-2500
 CCOP - Columbia River Oncology Program
 Janet Ruzich
Ph: 503-216-6260
 Kaiser Permanente Health Care - Portland
 Nagendra Tirumali, MD
Ph: 503-331-6500
 Legacy Emanuel Hospital and Health Center and Children's Hospital
 Clinical Trials Office - Legacy Emanuel Hospital and Health Center and Children's Hospital
Ph: 503-413-8199
 Legacy Good Samaritan Hospital & Comprehensive Cancer Center
 Clinical Trials Office - Legacy Good Samaritan Hospital & Comprehensive Cancer Center
Ph: 503-413-1742
 Providence Cancer Center at Providence Portland Medical Center
 Clinical Trials Office - Providence Cancer Center at Providence Portland Medical Center
Ph: 503-215-6412
 Providence St. Vincent Medical Center
 Clinical Trials Office - Providence St. Vincent Medical Center
Ph: 503-215-6412
  Tualatin
 Legacy Meridian Park Hospital
 Clinical Trials Office - Legacy Meridian Park Hospital
Ph: 503-413-1742
Pennsylvania
  Hershey
 Penn State Cancer Institute at Milton S. Hershey Medical Center
 Clinical Trials Office - Penn State Cancer Institute at Milton S. Hershey Medical Center
Ph: 717-531-3779
 Email: CTO@hmc.psu.edu
  Lancaster
 Lancaster General Hospital
 Randall Oyer
Ph: 717-544-5511
  Lewistown
 Lewistown Hospital
 Harold Harvey, MD
Ph: 717-531-8677
  Philadelphia
 Fox Chase Cancer Center - Philadelphia
 Clinical Trials Office - Fox Chase Cancer Center - Philadelphia
Ph: 215-728-4790
 Joan Karnell Cancer Center at Pennsylvania Hospital
 Bernard Mason, MD
Ph: 215-829-6088
 Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
 Clinical Trials Office - Kimmel Cancer Center at Thomas Jefferson University - Philadelphia
Ph: 215-955-6084
  Pittsburgh
 Allegheny Cancer Center at Allegheny General Hospital
 Robert Keenan, MD
Ph: 412-359-6202
 UPMC Cancer Centers
 Clinical Trials Office - UPMC Cancer Centers
Ph: 412-647-8073
 Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
 John Lister
Ph: 412-578-5000
  Reading
 St. Joseph Medical Center
 Patrick Colarusso, DO
Ph: 610-378-2385
  Sayre
 Guthrie Cancer Center at Guthrie Clinic Sayre
 Clinical Trials Office - Guthrie Cancer Center at Guthrie Clinic Sayre
Ph: 800-836-0388
  Scranton
 Hematology and Oncology Associates of Northeastern Pennsylvania
 Martin Hyzinski, MD
Ph: 570-558-3020
 Mercy Hospital Cancer Center - Scranton
 Martin Hyzinski, MD
Ph: 570-558-3020
  Sellersville
 Grand View Hospital
 Anthony Magdalinski, III
Ph: 215-453-4000
  State College
 Mount Nittany Medical Center
 Harold Harvey, MD
Ph: 717-531-8677
Rhode Island
  Cranston
 Hematology and Oncology Associates of Rhode Island
 Adam Olszewski
Ph: 401-943-4660
  Pawtucket
 Memorial Hospital of Rhode Island
 Humera Khurshid
Ph: 401-729-2000
  Providence
 Miriam Hospital
 Clinical Trials Office - Miriam Hospital
Ph: 401-793-2224
 Rhode Island Hospital Comprehensive Cancer Center
 Clinical Trials Office - Rhode Island Hospital Comprehensive Cancer Center
Ph: 401-444-1488
  Warwick
 Kent County Memorial Hospital
 Clinical Trials Office - Kent County Memorial Hospital
Ph: 401-737-7010 ext. 1864
South Carolina
  Charleston
 Hollings Cancer Center at Medical University of South Carolina
 Clinical Trials Office - Hollings Cancer Center at Medical University of South Carolina
Ph: 843-792-9321
 Roper St. Francis Cancer Center at Roper Hospital
 James Orcutt, MD
Ph: 843-577-2276
  Columbia
 Palmetto Health South Carolina Cancer Center
 Clinical Trials Office - Palmetto Health South Carolina Cancer Center
Ph: 803-434-3680
  Florence
 McLeod Regional Medical Center
 Clinical Trials Office - McLeod Regional Medical Center
Ph: 843-679-7256
  Greenville
 CCOP - Greenville
 Jeffrey Giguere, MD, FACP
Ph: 864-987-7000
South Dakota
  Aberdeen
 Oncology Services of Aberdeen
 Richard Conklin, MD
Ph: 605-622-5613
  Rapid City
 Rapid City Regional Hospital
 Richard Tenglin
Ph: 605-719-2360
  Sioux Falls
 Medical X-Ray Center, PC
 Loren Tschetter, MD
Ph: 605-328-8000
 Sanford Cancer Center at Sanford USD Medical Center
 Clinical Trials Office - Sanford Cancer Center
Ph: 605-328-1367
Tennessee
  Chattanooga
 Erlanger Cancer Center at Erlanger Hospital - Baroness
 Clinical Trials Office - Erlanger Cancer Center
Ph: 423-778-6947
  Knoxville
 Thompson Cancer Survival Center
 Clinical Trials Office - Thompson Cancer Survival Center
Ph: 865-541-1812
  Nashville
 MBCCOP - Meharry Medical College - Nashville
 Steven Wolff, MD
Ph: 615-327-6277
 Nashville Oncology Associates, PC
 Steven Wolff, MD
Ph: 615-327-6277
Texas
  Amarillo
 Harrington Cancer Center
 Clinical Trials Officec - Harrington Cancer Center
Ph: 806-359-4673
 Email: ryokubaitis@harringtoncc.org
  Dallas
 Medical City Dallas Hospital
 Barry Mirtsching, MD
Ph: 972-566-5588
 Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
 Clinical Trials Office - Simmons Comprehensive Cancer Center at University of Texas Southwestern Medical Center - Dallas
Ph: 866-460-4673; 214-648-7097
  Fort Sam Houston
 Brooke Army Medical Center
 Clinical Trials Office - Brooke Army Medical Center
Ph: 210-916-4837
  Lackland AFB
 Wilford Hall Medical Center
 Douglas Nelson, MD
Ph: 228-377-6588
Vermont
  Bennington
 Green Mountain Oncology Group
 Orion Howard
Ph: 802-442-1290
  Berlin
 Mountainview Medical
 Hyman Muss, MD
Ph: 802-656-5487
  Burlington
 Fletcher Allen Health Care - University Health Center Campus
 Clinical Trials Office - Fletcher Allen Health Care
Ph: 802-656-8990
Virginia
  Charlottesville
 Martha Jefferson Hospital Cancer Care Center
 Stefan Gorsch, MD
Ph: 434-982-8410
  Fredericksburg
 Fredericksburg Oncology, Incorporated
 Paul Schaefer, MD
Ph: 419-479-5605
  Hampton
 Virginia Oncology Associates - Hampton
 Paul Conkling, MD
Ph: 757-466-8683
  Lynchburg
 Lynchburg Hematology-Oncology Clinic
 John Leach MacNeill, MD
Ph: 434-947-5925
  Roanoke
 Carilion Cancer Center of Western Virginia
 Paul Richards, MD
Ph: 540-774-8660
Washington
  Auburn
 Auburn Regional Center for Cancer Care
 Lauren Colman, MD
Ph: 253-403-1677
  Bellingham
 St. Joseph Cancer Center
 Saul Rivkin, MD
Ph: 206-386-2441
  Bremerton
 Olympic Hematology and Oncology
 Saul Rivkin, MD
Ph: 206-386-2441
  Centralia
 Providence Centralia Hospital
 Clinical Trials Office - Providence Centralia Hospital
Ph: 360-493-4300
  Federal Way
 St. Francis Hospital
 Lauren Colman, MD
Ph: 253-403-1677
  Kennewick
 Columbia Basin Hematology
 Saul Rivkin, MD
Ph: 206-386-2441
  Kirkland
 Cascade Cancer Center at Evergreen Hospital Medical Center
 Eva Perdahl-Wallace
Ph: 425-899-3181
  Olympia
 Providence St. Peter Hospital Regional Cancer Center
 Lauren Colman, MD
Ph: 253-403-1677
  Port Angeles
 Olympic Medical Center
 Eva Perdahl-Wallace
Ph: 360-417-7139
  Puyallup
 Good Samaritan Cancer Center
 Lauren Colman, MD
Ph: 253-403-1677
  Renton
 Valley Medical Center
 Eva Perdahl-Wallace
Ph: 425-228-3450
  Seattle
 CCOP - Virginia Mason Research Center
 Eva Perdahl-Wallace
Ph: 206-341-0446
 Group Health Central Hospital
 Clinical Trials Office - Group Health Central Hospital
Ph: 206-287-2900
 Minor and James Medical, PLLC
 Saul Rivkin, MD
Ph: 206-386-2441
 Polyclinic First Hill
 Saul Rivkin, MD
Ph: 206-386-2441
 Swedish Cancer Institute at Swedish Medical Center - First Hill Campus
 Saul Rivkin, MD
Ph: 206-386-2441
 University Cancer Center at University of Washington Medical Center
 Clinical Trials Office - University Cancer Center at University of Washington Medical Center
Ph: 206-616-8289
  Spokane
 Cancer Care Northwest - Spokane South
 Clinical Trials Office - Cancer Care Northwest - Spokane South
Ph: 509-228-1083
 Providence Cancer Center at Holy Family Hospital